Radiocarbon and DNA evidence for a pre-Columbian introduction of Polynesian chickens to Chile.

abstract：:Some pathogenesis-related genes are expressed in fungi only when the pathogen is in the host, but the host signals that trigger these gene expressions have not been identified. Virulent Nectria haematococca infects pea plants and requires either pelA, which is induced by pectin, or pelD, which is induced only in plant...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yang Z,Rogers LM,Song Y,Guo W,Kolattukudy PE

更新日期：2005-03-15 00:00:00

abstract：:Although aquaporin 5 (AQP5) is the major water channel expressed in alveolar type I cells in the lung, its actual role in the lung is a matter of considerable speculation. By using immunohistochemical staining, we show that AQP5 expression in mouse lung is not restricted to type I cells, but is also detected in alveol...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Krane CM,Fortner CN,Hand AR,McGraw DW,Lorenz JN,Wert SE,Towne JE,Paul RJ,Whitsett JA,Menon AG

更新日期：2001-11-20 00:00:00

abstract：:We report potent inhibition of the Mg(II).ATP-dependent protein phosphatase, Fc.M, by the regulatory subunit dimer of type II cAMP-dependent protein kinase, RII2. The protein kinase catalytic subunit has no effect on phosphatase activity and is unable to substitute for kinase FA in the kinase FA- and Mg(II).ATP-mediat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jurgensen SR,Chock PB,Taylor S,Vandenheede JR,Merlevede W

更新日期：1985-11-01 00:00:00

abstract：:AB5 bacterial toxins and polyomaviruses induce membrane curvature as a mechanism to facilitate their entry into host cells. How membrane bending is accomplished is not yet fully understood but has been linked to the simultaneous binding of the pentameric B subunit to multiple copies of glycosphingolipid receptors. Her...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kabbani AM,Raghunathan K,Lencer WI,Kenworthy AK,Kelly CV

更新日期：2020-06-30 00:00:00

abstract：:Estimates of 21st Century global-mean surface temperature increase have generally been based on scenarios that do not include climate policies. Newly developed multigas mitigation scenarios, based on a wide range of modeling approaches and socioeconomic assumptions, now allow the assessment of possible impacts of clim...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Van Vuuren DP,Meinshausen M,Plattner GK,Joos F,Strassmann KM,Smith SJ,Wigley TM,Raper SC,Riahi K,de la Chesnaye F,den Elzen MG,Fujino J,Jiang K,Nakicenovic N,Paltsev S,Reilly JM

更新日期：2008-10-07 00:00:00

abstract：:The operon model was proposed by Jacob and Monod in 1961 to explain the regulation of enzyme synthesis in bacteria. The model requires two genetic elements: a locus i which directs the synthesis of a repressor, and a locus called the operon which contains an operator gene and associated structural genes. The repressor...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zubay G,Lederman M

更新日期：1969-02-01 00:00:00

abstract：:A deficit in early clearance of Pseudomonas aeruginosa (P. aeruginosa) is crucial in nosocomial pneumonia and in chronic lung infections. Few studies have addressed the role of Toll-like receptors (TLRs), which are early pathogen associated molecular pattern receptors, in pathogen uptake and clearance by alveolar macr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Descamps D,Le Gars M,Balloy V,Barbier D,Maschalidi S,Tohme M,Chignard M,Ramphal R,Manoury B,Sallenave JM

更新日期：2012-01-31 00:00:00

abstract：:Endogenous retroviruses (ERVs) are the remnants of ancient retroviral infections of germ cells and have been maintained in whole or part as heritable genomic elements. The last known endogenization events occurred several million years ago, and therefore stepwise analysis of retroviral endogenization has not been poss...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Oliveira NM,Satija H,Kouwenhoven IA,Eiden MV

更新日期：2007-10-30 00:00:00

abstract：:Malignant myeloid leukemic cells and normal macrophages and granulocytes have functional beta-adrenergic receptors, which have been quantitated by radioreceptor binding with the beta-adrenergic antagonist [(3)H]dihydroalprenolol and by induction of cyclic AMP by adrenergic hormones. Both the normal and leukemic cells ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Simantov R,Sachs L

更新日期：1978-04-01 00:00:00

abstract：:Transient cytosolic Ca(2+) ([Ca(2+)](cyt)) elevations are early events in plant signaling pathways including those related to abiotic stress. The restoration of [Ca(2+)](cyt) to prestimulus levels involves ATP-driven Ca(2+) pumps, but direct evidence for an essential role of a plant Ca(2+)-ATPase in abiotic stress ada...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Qudeimat E,Faltusz AM,Wheeler G,Lang D,Holtorf H,Brownlee C,Reski R,Frank W

更新日期：2008-12-09 00:00:00

abstract：:Color and black and white line stimulation produce qualitatively and quantitatively different 2-deoxy[14C]glucose column patterns in the striate cortex of macaque monkeys. Microdensitometry of these stimulus-dependent columns reveals interlaminar density differences that serve as a signature for the stimulus condition...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Crawford ML,Meharg LS,Johnston DA

更新日期：1982-11-01 00:00:00

abstract：:In normal vision, shifts of attention are usually followed by saccadic eye movements. Neurons in extrastriate area V4 are modulated by focal attention when eye movements are withheld, but they also respond in advance of visually guided saccadic eye movements. We have examined the visual selectivity of saccade-related ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moore T,Tolias AS,Schiller PH

更新日期：1998-07-21 00:00:00

abstract：:The dansyl-conjugated (Dns) peptides Dns-Pro-Gly-Gly-Gln-Gln-Ile-Val and Dns-Ala-Gln-Gln-Ile-Val, patterned on the N-terminal sequence of fibronectin, were synthesized and used for the transglutaminase (protein-glutamine:amine gamma-glutamyltransferase, EC 2.3.2.13)-directed selective blocking of lens proteins that ot...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lorand L,Parameswaran KN,Velasco PT

更新日期：1991-01-01 00:00:00

abstract：:Linkage disequilibrium between polymorphisms in a natural population may result from various evolutionary forces, including random genetic drift due to sampling of gametes during reproduction, restricted migration between subpopulations in a subdivided population, or epistatic selection. In this report, we present evi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kirby DA,Muse SV,Stephan W

更新日期：1995-09-26 00:00:00

abstract：:We recently isolated an RNA polymerase II elongation factor from rat liver nuclei and found it to be homologous to the product of the human ELL gene, a frequent target for translocations in acute myeloid leukemia. To further our understanding of the possible role(s) of ELL in transcriptional regulation and human disea...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shilatifard A,Duan DR,Haque D,Florence C,Schubach WH,Conaway JW,Conaway RC

更新日期：1997-04-15 00:00:00

abstract：:In colloidal systems, the interplay between the short range attraction and long-range repulsion can lead to a low density associated state consisting of clusters of individual particles. Recently, such an equilibrium cluster phase was also reported for concentrated solutions of lysozyme at low ionic strength and close...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shukla A,Mylonas E,Di Cola E,Finet S,Timmins P,Narayanan T,Svergun DI

更新日期：2008-04-01 00:00:00

abstract：:In layered materials, a common mode of deformation involves buckling of the layers under tensile deformation in the direction perpendicular to the layers. The instability mechanism, which operates in elastic materials from geological to nanometer scales, involves the elastic contrast between different layers. In a reg...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Makke A,Perez M,Lame O,Barrat JL

更新日期：2012-01-17 00:00:00

abstract：:An epithelial cell line, designated COMMA-1D, was derived from mammary tissue of BALB/c mice in the middle of pregnancy. This line, in continuous cell culture for 12 months, exhibits several characteristics distinctive of normal mammary epithelial cells, including induction of casein synthesis in vitro and normal duct...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Danielson KG,Oborn CJ,Durban EM,Butel JS,Medina D

更新日期：1984-06-01 00:00:00

abstract：:Nitric oxide (NO), synthesized from L-arginine by NO synthases (NOS), plays an essential role in the regulation of cerebrovascular tone. Adenoviral vectors have been widely used to transfer recombinant genes to different vascular beds. To determine whether the recombinant endothelial NOS (eNOS) gene can be delivered i...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chen AF,Jiang SW,Crotty TB,Tsutsui M,Smith LA,O'Brien T,Katusic ZS

更新日期：1997-11-11 00:00:00

abstract：:Division of labor among the workers of insect societies is a conspicuous feature of their biology. Social tasks are commonly shared among age groups but not between larvae and adults with completely different morphologies, as in bees, wasps, ants, and beetles (i.e., Holometabola). A unique yet hardly studied holometab...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Biedermann PH,Taborsky M

更新日期：2011-10-11 00:00:00

abstract：:How cells achieve their final sizes is a pervasive biological question. One strategy to increase cell size is for the cell to amplify its chromosomal DNA content through endoreduplication cycles. Although endoreduplication is widespread in eukaryotes, we know very little about its molecular mechanisms. Successful prog...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sugimoto-Shirasu K,Roberts GR,Stacey NJ,McCann MC,Maxwell A,Roberts K

更新日期：2005-12-20 00:00:00

abstract：:The kinetics of biomolecular isomerization processes, such as protein folding, is governed by a free-energy surface of high dimensionality and complexity. As an alternative to projections into one or two dimensions, the free-energy surface can be mapped into a weighted network where nodes and links are configurations ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gfeller D,De Los Rios P,Caflisch A,Rao F

更新日期：2007-02-06 00:00:00

abstract：:Many of the mutagenic or lethal effects of ionization radiation can be attributed to damage caused to the DNA by low-energy electrons. To gain insight on the parameters affecting this process, we measured the low-energy electron (<2 eV) transmission yield through self-assembled monolayers of short DNA oligomers. The e...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ray SG,Daube SS,Naaman R

更新日期：2005-01-04 00:00:00

abstract：:Circadian rhythms describe biological phenomena that oscillate with an approximately 24-hour cycle. These rhythms include blood pressure, body temperature, hormone levels, the number of immune cells in blood, and the sleep-wake cycle. In this paper, we will focus on common genes between species that are responsible fo...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ishida N,Kaneko M,Allada R

更新日期：1999-08-03 00:00:00

abstract：:The nuclear receptor REV-ERBα integrates the circadian clock with hepatic glucose and lipid metabolism by nucleating transcriptional comodulators at genomic regulatory regions. An interactomic approach identified O-GlcNAc transferase (OGT) as a REV-ERBα-interacting protein. By shielding cytoplasmic OGT from proteasoma...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Berthier A,Vinod M,Porez G,Steenackers A,Alexandre J,Yamakawa N,Gheeraert C,Ploton M,Maréchal X,Dubois-Chevalier J,Hovasse A,Schaeffer-Reiss C,Cianférani S,Rolando C,Bray F,Duez H,Eeckhoute J,Lefebvre T,Staels B,Lef

更新日期：2018-11-20 00:00:00

abstract：:The folate-binding protein of rat liver mitochondria [Zamierowski, M. & Wagner, C. (1977) J. Biol. Chem. 252, 933-938] has been purified to homogeneity by a combination of gel filtration, DEAE-cellulose, and affinity chromatography. This protein was assayed by its ability to bind tetrahydro[3H]folic acid in vitro. the...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wittwer AJ,Wagner C

更新日期：1980-08-01 00:00:00

abstract：:Positively acting, rate-limiting regulatory factors that influence tissue-specific expression of the human cardiac alpha-actin gene in a mouse muscle cell line are shown by in vivo competition and gel mobility-shift assays to bind to upstream regions of its promoter but to neither vector DNA nor a beta-globin promoter...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Miwa T,Boxer LM,Kedes L

更新日期：1987-10-01 00:00:00

abstract：:We previously purified a 48-kDa protein (p48) that specifically reacts with an antiserum directed against the 12 carboxyl-terminal amino acids of the c-myc gene product. Using an antiserum directed against the purified p48, we have cloned a cDNA from a human expression library. This cDNA hybrid-selects an mRNA that tr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Giallongo A,Feo S,Moore R,Croce CM,Showe LC

更新日期：1986-09-01 00:00:00

abstract：:The improvement of motor behavior, based on experience, is a form of learning that is critically dependent on the cerebellum. A well studied example of cerebellar motor learning is short-term saccadic adaptation (STSA). In STSA, information on saccadic errors is used to improve future saccades. The information optimiz...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Catz N,Dicke PW,Thier P

更新日期：2008-05-20 00:00:00

abstract：:The immunoglobulin light chain is thought to be organized into two structural domains, the constant and the variable regions, linked by a switch region of lesser tertiary organization. Light chains of homogeneous rabbit antibodies to pneumococcal polysaccharides labeled with (125)I were subjected to trypsin digestion ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Poulsen K,Fraser KJ,Haber E

更新日期：1972-09-01 00:00:00