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Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported.

Abstract：

OBJECTIVE:To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 25-year-old woman with left adnexal mass and extremely elevated serum CA-125 level, 7,900 U/mL, underwent laparoscopy. There were unilateral endometrioma and stage IV endometriosis. INTERVENTION(S):Laparoscopic excision of the endometrioma, unilateral salpingectomy, adhesiolysis, ablation of endometriotic foci, and partial omentectomy were performed, and histopathologic results confirmed the diagnosis of endometriosis. MAIN OUTCOME MEASURE(S):Extremely elevated serum CA-125 levels and unruptured ovarian endometrioma. RESULT(S):On the second, sixth, and 13th days of the menstrual period, serum CA-125 levels were 7,900 U/mL, 1,577 U/mL, and 627 U/mL, respectively. On the third postoperative day serum CA-125 level was 56 U/mL. CONCLUSION(S):Ovarian endometrioma and advanced endometriosis may be associated with extremely elevated serum CA-125 levels. For this reason ovarian endometrioma should be considered with respect to differential diagnosis of reproductive-age women presenting with an ovarian mass even if it resembles an ovarian malignancy.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Kahraman K,Ozguven I,Gungor M,Atabekoglu CS

doi

10.1016/j.fertnstert.2006.12.076

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

968.e15-7

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(07)00063-5

journal_volume

88

pub_type

杂志文章

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