Group A streptococcal infections in children.

Abstract:

:The group A streptococcus causes the widest range of disease in humans of all bacterial pathogens. Group A streptococcal diseases are more common in children than adults with diseases ranging from pharyngitis and impetigo to invasive infections and the post-streptococcal sequelae--acute rheumatic fever and acute post-streptococcal glomerulonephritis. The global burden of severe group A streptococcal disease is concentrated largely in developing countries and Indigenous populations such as Aboriginal Australians. Control of group A streptococcal disease is poor in these settings and the need for a vaccine has been argued. With an ever-increasing understanding of the group A streptococcus at a molecular level, new and sophisticated vaccines are currently in human trials and the next decade holds exciting prospects for curbing group A streptococcal diseases.

authors

Steer AC,Danchin MH,Carapetis JR

doi

10.1111/j.1440-1754.2007.01051.x

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

203-13

issue

4

eissn

1034-4810

issn

1440-1754

pii

JPC1051

journal_volume

43

pub_type

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