Abstract：
AIM:Management of congenital pulmonary airway malformations (CPAM) is controversial, especially for asymptomatic patients. We aim to describe the clinical manifestations and management of CPAM at a tertiary paediatric hospital using a retrospective audit. METHODS:Infants with CPAM were identified on the Fetal Diagnostic Unit database from 2007 to 2014. Information on antenatal and post-natal management was collected from medical record. RESULTS:Thirty-five infants with antenatally diagnosed CPAM were included. Fetal CPAM volume ratio (CVR) was calculated from antenatal ultrasound measurement and used to categorise the infants into three groups of large (CVR ≥ 1.6, n = 8), medium (CVR of 0.5-1.6, n = 12) and small CPAM (CVR of ≤0.5, n = 15), respectively. Ten infants (10/35 = 29%) were symptomatic in the neonatal period. Overall, nine infants (26%) had surgical resection, among whom eight had large or medium-sized CPAM lesions as defined by the antenatal CVR. Three infants had neonatal emergency surgery and the remaining six had late elective surgery. Histology of eight cases showed CPAM, but one case showed congenital lobar emphysema. Criteria for surgery varied and included persistent symptoms after birth, complications during childhood and persistently abnormal chest X-ray. Most asymptomatic infants with CPAM were safely managed using a conservative approach, with no significant increase in late symptoms or complications. CONCLUSIONS:Conservative management of CPAM may be considered for infants/children who remain asymptomatic, especially those with a small lesion. For large and medium-sized CPAM, delineation using computed tomography is required, and surgery may be beneficial to prevent late symptoms and the risk of emergency surgery.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Makhijani AV,Wong FYdoi
10.1111/jpc.13727subject
Has Abstractpub_date
2018-03-01 00:00:00pages
267-271issue
3eissn
1034-4810issn
1440-1754journal_volume
54pub_type
杂志文章abstract：:Two hundred and seven Australian paediatricians were sent a questionnaire to determine whether they undertook developmental screening and/or assessment. Replies were received from 140 (68%) paediatricians of whom 115 (82%) stated they did developmental screening and 58 (41%) said they did developmental assessment. The...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1993.tb00534.x
更新日期：1993-10-01 00:00:00
abstract：:Clinical audits should underpin everything we do as clinicians - to constantly evaluate and improve our day-to-day clinical practice. Errors in practice, suboptimal practice or inefficiencies can occur in any part of our health-care system, despite the training and best intentions of health-care professionals. Audits ...
journal_title：Journal of paediatrics and child health
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journal_title：Journal of paediatrics and child health
pub_type： 临床试验,杂志文章
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更新日期：2004-08-01 00:00:00
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doi：10.1111/jpc.12684
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journal_title：Journal of paediatrics and child health
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1993.tb03016.x
更新日期：1993-12-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2011.02178.x
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journal_title：Journal of paediatrics and child health
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doi：10.1111/j.1440-1754.2012.02432.x
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journal_title：Journal of paediatrics and child health
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1994-08-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13775
更新日期：2018-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00642.x
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2003.00074.x
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journal_title：Journal of paediatrics and child health
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journal_title：Journal of paediatrics and child health
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doi：10.1111/j.1440-1754.1994.tb00626.x
更新日期：1994-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00040.x
更新日期：2002-10-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
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更新日期：2021-01-15 00:00:00
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journal_title：Journal of paediatrics and child health
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更新日期：2016-07-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.1999.00339.x
更新日期：1999-02-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14964
更新日期：2020-09-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1996.tb00917.x
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVES:We observed a reduced incidence of necrotizing enterocolitis (NEC) despite increased survival of extremely premature infants over the last two decades. A different susceptibility pattern to NEC according to gestation has been proposed. We aim to examine the influence of perinatal risk factors for NEC in infa...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00583.x
更新日期：2005-04-01 00:00:00
