Adrenal cortical tumours: 25 years' experience at the Royal Children's Hospital, Melbourne.

Abstract:

AIMS:Adrenal cortical tumours remain a rare entity with inconsistent consensus about treatment and follow up. This article reviews 25 years of experience in the Royal Children's Hospital, Melbourne, Australia. METHODS:All records with the diagnosis of adrenal adenoma or carcinoma between 1976 and 2001 were reviewed, excluding tumours of the adrenal medulla. Details were recorded for age, gender, family history, presentation, biochemistry, imaging, histology, diagnosis, treatment and outcome. RESULTS:Twelve children (six boys, six girls) were diagnosed with adrenal cortical tumours in this period. Median age at diagnosis was 2.5 years (range 0.5-15.6 years). Six of the 12 children presented with virilization. The remaining six identified by ultrasound performed for hemi-hypertrophy (2), hypertension (2), and fever with abdominal pain (2). Five children had a family history of tumour and two of these five had a p53 mutation demonstrated on molecular genetic analysis. Tumours in five of the 12 children were defined as malignant on histology. Surgery was deemed curative in nine cases. Only one case required further surgery and two required chemotherapy. Time since diagnosis ranged from 1 to 25.8 years. Two children died from complications of the tumour. One other child died following development of a second tumour. CONCLUSION:Adrenal cortical tumours should always be considered in the differential for adrenal hormone excess. New information provided by mutational analysis may predict ongoing risks. Lifelong regular follow up is required.

authors

McDonnell CM,Zacharin MR

doi

10.1046/j.1440-1754.2003.00268.x

keywords:

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

682-5

issue

9

eissn

1034-4810

issn

1440-1754

pii

268

journal_volume

39

pub_type

杂志文章
  • Shopping trolley-related injuries to children in New Zealand, 1988-97.

    abstract:OBJECTIVE:To describe the epidemiology of shopping trolley related injuries (fatalities and hospitalizations) to children in New Zealand prior to the introduction of a voluntary standard for shopping trolleys. METHODOLOGY:To identify cases, a key word search was conducted of national mortality and hospitalization data...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2002.00708.x

    authors: Parry ML,Morrison LG,Chalmers DJ,Wright CS

    更新日期:2002-02-01 00:00:00

  • Factors impacting parental burden in food-allergic children.

    abstract:AIM:This study aims to determine factors impacting the parental burden in immunoglobulin E (IgE)-mediated food-allergic children (FAC), focusing on attitudes towards adrenaline autoinjectors (AAIs). METHODS:Questionnaires were sent to parents of diagnosed IgE-mediated FAC attending follow-up allergy clinic appointment...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.12794

    authors: Allen CW,Bidarkar MS,vanNunen SA,Campbell DE

    更新日期:2015-07-01 00:00:00

  • Pre- and post-intervention study examining immunisation rates, documentation, catch-up delivery and the impact of a dedicated immunisation service at a tertiary paediatric hospital.

    abstract:AIM:To explore immunisation rates and catch-up delivery to children admitted to hospital before and after an immunisation service was commenced. METHODS:This pre- and post-intervention study examined 300 admissions prior to (cohort 1) and 300 following (cohort 2) the introduction of an immunisation service. Immunisati...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.15217

    authors: Tarca AJ,Lau GT,Mascaro F,Clifford P,Campbell AJ,Taylor E

    更新日期:2020-10-14 00:00:00

  • Increased prevalence of constipation in pre-school children is attributable to under-consumption of plant foods: A community-based study.

    abstract:AIM:To evaluate consumption of foods rich in dietary fibre and its relation to the prevalence of constipation in pre-school children. METHODS:In total, 368 children aged 3-5 years were randomly selected from kindergartens in Hong Kong. Constipation was confirmed by Rome-criteria. Children with normal bowel habits serv...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2007.01212.x

    authors: Lee WT,Ip KS,Chan JS,Lui NW,Young BW

    更新日期:2008-04-01 00:00:00

  • Diagnostic accuracy of paediatric echocardiograms interpreted by individuals other than paediatric cardiologists.

    abstract:OBJECTIVE:To assess the diagnostic error rate among echocardiograms undertaken by individuals other than paediatric cardiologists in our referral area. METHODOLOGY:External group: The charts and echocardiographic results of all patients who had undergone outside echocardiograms between January 1996 and December 1999 w...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00695.x

    authors: Ward CJ,Purdie J

    更新日期:2001-08-01 00:00:00

  • Acquired facial palsy with hypertension secondary to Guillain-Barre syndrome.

    abstract::Most cases of facial nerve paresis are idiopathic (Bell's palsy). However, rare and potentially dangerous conditions may present in this manner. We report 2 children presenting with unilateral lower motor neuron facial nerve palsy and hypertension. A diagnosis of Guillain-Barre syndrome was made in both; literature li...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2009.01650.x

    authors: Smith N,Grattan-Smith P,Andrews IP,Kainer G

    更新日期:2010-03-01 00:00:00

  • Asthma and sleep disturbance in adolescents and young adults: A cohort study.

    abstract:AIMS:A longitudinal birth cohort provides an opportunity to study the impact of childhood conditions persisting into adulthood. This study examines the cross-sectional association of asthma with sleep quality and snoring in the adolescent and young adult population and the extent to which asthma, sleep quality and snor...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.13234

    authors: Garden M,O'Callaghan M,Suresh S,Mamum AA,Najman JM

    更新日期:2016-11-01 00:00:00

  • Rollerblading injuries in young people.

    abstract:OBJECTIVE:To study injuries in young people associated with the use of rollerblades, draw comparisons with skateboarding and rollerskating injuries, and suggest strategies for injury prevention. METHODOLOGY:Injuries associated with the use of rollerblades, skateboards and rollerskates in young people aged < or = 14 ye...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1996.tb01538.x

    authors: Heller DR,Routley V,Chambers S

    更新日期:1996-02-01 00:00:00

  • Outbreak of variant hand-foot-and-mouth disease caused by coxsackievirus A6 in Auckland, New Zealand.

    abstract::Hand-foot-and-mouth disease is a common, usually mild childhood illness caused by enteroviruses. Over the last five years, coxsackievirus A6 has been identified as a causative agent in outbreaks in Europe, South-East Asia and America. It has an atypical presentation compared with other enteroviruses, with more widespr...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.12708

    authors: Hayman R,Shepherd M,Tarring C,Best E

    更新日期:2014-10-01 00:00:00

  • Pre-excitation syndrome secondary to cardiac rhabdomyomas in tuberous sclerosis.

    abstract::Rhabdomyomas are not uncommon in infants with tuberous sclerosis. We describe a neonate who presented with hydrops fetalis arising from a tachyarrhythmia during fetal life related to rhabdomyomas. After reversion of the arrhythmia, pre-excitation was noted on an interval electrocardiogram. Following regression of the ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2000.00443.x

    authors: Mas C,Penny DJ,Menahem S

    更新日期:2000-02-01 00:00:00

  • Factors associated with breastfeeding at discharge and duration of breastfeeding.

    abstract:OBJECTIVE:To identify determinants of the initiation and duration of breastfeeding amongst Australian women. METHODS:A prospective cohort study of 556 women in Perth, Western Australia and 503 women from the Darling Downs area, Queensland, Australia. RESULTS:Breastfeeding at discharge was most strongly associated wit...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00646.x

    authors: Scott JA,Landers MC,Hughes RM,Binns CW

    更新日期:2001-06-01 00:00:00

  • Sudden infant death syndrome in South Australia 1968-97. Part 3: is bed sharing safe for infants?

    abstract:OBJECTIVE:To examine the risk of death for bed-sharing infants. METHODOLOGY:All unexpected infant deaths occurring in South Australia between 1970 and 1997, occurring after the infant was put to rest and diagnosed by after death scene investigation and autopsy as sudden death infant syndrome, accidental death, or 'und...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2000.00548.x

    authors: Beal SM,Byard RW

    更新日期:2000-12-01 00:00:00

  • Two unusual tumours of the gastrointestinal tract in a patient with tuberous sclerosis.

    abstract::A 16 year old girl with an established diagnosis of tuberous sclerosis presented with a 1 year history of swelling of the left cheek. A 2 cm diameter tumour was excised which showed histological features of a solid variant of a minor salivary gland basal cell adenoma. One year later during laparotomy and excision of m...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1754.1991.tb00365.x

    authors: Byard RW,Phillips GE,Dardick I,Robertson E,Carter RF,Bourne AJ

    更新日期:1991-04-01 00:00:00

  • Ethical considerations in paediatric neurology: neuromuscular disease and epilepsy.

    abstract::The pace of developing technology with respect to many diagnostic tests, as well as available treatments including artificial ventilation, may have progressed at a faster rate than our ethical, humane ability to decide on the optimal choices for our patients. In fact, who should make these choices; physicians or patie...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2011.02159.x

    authors: Bodensteiner JB,Ng YT

    更新日期:2011-09-01 00:00:00

  • Macronutrient and fibre intake of young Spanish children with reference to their in utero growth status: Are they eating a healthy diet?

    abstract:AIM:To compare macronutrient and fibre intake by pre-school children born with intra-uterine growth restriction (IUGR) or as appropriate for gestational age (AGA) and to compare their intake with paediatric nutritional recommendations for identification of potential areas of modification during early life. METHODS:A p...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.13815

    authors: Nuruddin R,Urpi-Sarda M,Rodriguez-Lopez M,Garcia-Arenas D,Gratacos E,Crispi F,Acosta-Rojas R

    更新日期:2018-05-01 00:00:00

  • Sudden infant death syndrome and infant mortality in aboriginal and non-aboriginal infants.

    abstract::The aim of this study was to investigate sudden infant death syndrome (SIDS) in the context of total infant mortality for Aboriginal and non-Aboriginal infants. Deaths for infants born in Western Australia from 1980 to 1988 inclusive were ascertained from a total population data base. Infant mortality rates and rates ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1994.tb00626.x

    authors: Alessandri LM,Read AW,Stanley FJ,Burton PR,Dawes VP

    更新日期:1994-06-01 00:00:00

  • Epidemiology of childhood nocturnal enuresis in Malaysia.

    abstract:OBJECTIVES:To estimate the prevalence of nocturnal enuresis in primary school children in Malaysia and to determine the factors associated with primary nocturnal enuresis. METHODS:This was a cross-sectional survey. A total of 3371 self-administered questionnaires were distributed to parents of children aged 7, 9 and 1...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2003.00105.x

    authors: Kanaheswari Y

    更新日期:2003-03-01 00:00:00

  • Current legal and clinical framework for treatment of trans and gender diverse youth in Australia.

    abstract::Legal and clinical complexities surrounding consent to medical treatment for trans and gender diverse (TGD) youth in Australia continue to develop. New Australian Standards of Care and Treatment Guidelines have also introduced substantial clinical developments. Significant changes to legal principles from court decisi...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.15181

    authors: Jowett S,Mathews B

    更新日期:2020-12-01 00:00:00

  • Parental attitudes to the identification of their infants as carriers of cystic fibrosis by newborn screening.

    abstract:AIM:To investigate parental attitudes to cystic fibrosis (CF) carrier detection of their infant by newborn screening (NBS). METHODS:Data were collected from a postal questionnaire sent to parents of infants identified as CF carriers by NBS in 1996-1997 (inclusive) and 2001 in Victoria, Australia (n = 66). RESULTS:Alm...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2006.00917.x

    authors: Lewis S,Curnow L,Ross M,Massie J

    更新日期:2006-09-01 00:00:00

  • Hair-thread tourniquet syndrome.

    abstract::We report a case of hair-thread tourniquet syndrome involving the labia majora of a 14-year-old autistic child. 'Hair-thread tourniquet' refers to the process whereby a thread of hair leads to the ischaemic strangulation of an appendage or other piece of tissue. Uncommonly recognized, this syndrome has gradually gaine...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1754.2005.00569.x

    authors: Golshevsky J,Chuen J,Tung PH

    更新日期:2005-03-01 00:00:00

  • Severity of rotavirus infection in relation to serotype, monotype and electropherotype.

    abstract::The aim of this study was to determine whether the severity of symptoms associated with rotavirus infection was related to the serotype of the infecting virus. Severity of clinical symptoms in 108 children admitted to hospital for treatment of rotavirus diarrhoea was retrospectively assessed using a scoring system for...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1992.tb02618.x

    authors: Barnes GL,Unicomb L,Bishop RF

    更新日期:1992-02-01 00:00:00

  • Engaging parents in child obesity prevention: support preferences of parents.

    abstract::Helping parents engage in practices that are likely to prevent childhood obesity is a considerable challenge for health professionals, policy makers and researchers. The aim of the study was to determine who is likely to use services designed to help parents prevent overweight and obesity and what types of services th...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2010.01776.x

    authors: Wolfenden L,Bell C,Wiggers J,Butler M,James E,Chipperfield K

    更新日期:2012-02-01 00:00:00

  • Neuronal ceroid lipofuscinosis type 2: an Australian case series.

    abstract:AIM:Late infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease is a rare neurodegenerative disorder presenting in children aged 2-4 years with seizures and loss of motor and language skills, followed by blindness and death in late childhood. Initial presenting features are similar to a range of common epilepsi...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.14890

    authors: Johnson AM,Mandelstam S,Andrews I,Boysen K,Yaplito-Lee J,Fietz M,Nagarajan L,Rodriguez-Casero V,Ryan MM,Smith N,Scheffer IE,Ellaway C

    更新日期:2020-08-01 00:00:00

  • World Health Organization growth charts for monitoring the growth of Australian children: time to begin the debate.

    abstract::The recently released World Health Organization growth charts are methodologically robust, as well as clinically useful tools for monitoring the growth of children. They have been endorsed by premier organisations such as the Royal College of Paediatrics and Child Health (UK), Canadian Pediatric Society, Australian Br...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1754.2011.02214.x

    authors: Rao S,Simmer K

    更新日期:2012-02-01 00:00:00

  • Sensitivity and specificity of General Movements Assessment for diagnostic accuracy of detecting cerebral palsy early in an Australian context.

    abstract:AIM:The aim of this study was to calculate the sensitivity and specificity of the General Movements Assessment (GMA) for estimating diagnostic accuracy in detecting cerebral palsy (CP) in an Australian context by a newly established NSW rater network. METHODS:A prospective longitudinal cross-sectional study was conduc...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.12995

    authors: Morgan C,Crowle C,Goyen TA,Hardman C,Jackman M,Novak I,Badawi N

    更新日期:2016-01-01 00:00:00

  • Reference ranges for blood pressure in preschool Australians, obtained by oscillometry.

    abstract:OBJECTIVE:To derive reference centiles for blood pressure in children aged 1-6 years which seek to address shortcomings in available reference ranges. METHODS:Prospective cohort study of 2876 children in Perth, Western Australia, commenced in 1989 with serial blood pressure measurements through early childhood obtaine...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2000.00445.x

    authors: Blake KV,Gurrin LC,Evans SF,Newnham JP,Landau LI,Stanley FJ,Beilin LJ

    更新日期:2000-02-01 00:00:00

  • Superior vena cava obstruction: dangers of a missed diagnosis.

    abstract::We report the case of a 7 year old girl who presented to the Children's Emergency Department with a 6 week history of bilateral facial and neck swelling. She had felt generally unwell, tired, with a recent onset of dry cough, and had presented multiple times to her general practitioner (GP) who after initially unsucce...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2010.01741.x

    authors: Holme H,Nanduri V

    更新日期:2011-03-01 00:00:00

  • Call for a national plan for rare diseases.

    abstract::Australia requires a national plan, similar to plans developed internationally, to address the impacts of rare diseases on individuals, the community and health services. Rare diseases often present in childhood, many are chronic, some life threatening and others associated with significant disability. However, diagno...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2009.01608.x

    authors: Jaffe A,Zurynski Y,Beville L,Elliott E

    更新日期:2010-01-01 00:00:00

  • Are teething gels safe or even necessary for our children? A review of the safety, efficacy and use of topical lidocaine teething gels.

    abstract::Lidocaine-based teething gels have been widely available in Australia for decades in both commercial preparations and those compounded by pharmacies. However, many case reports have highlighted potential risks and toxicity associated with lidocaine-based teething gels when used in infants and young children, including...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1111/jpc.14769

    authors: Teoh L,Moses GM

    更新日期:2020-04-01 00:00:00

  • A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze.

    abstract::The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study. A 4 week no-medication baseline phase preceded the 16 week treatment phase in which infants took 2.5 ...

    journal_title:Journal of paediatrics and child health

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1440-1754.1992.tb02714.x

    authors: van Asperen PP,McKay KO,Mellis CM,Loh RK,Harth SC,Thong YH,Harris M,Robertson IF,Gibbeson M,Rhodes L

    更新日期:1992-12-01 00:00:00