Abstract:
:We investigated the role of single nucleotide polymorphisms in genes encoding for drug-metabolizing enzymes in 209 newly diagnosed multiple myeloma patients included in a clinical trial comparing single with double intensive therapy. We observed no significant association between polymorphisms in CYP3A4, CYP3A5, MDR1, GSTM1 and GSTT1 and outcome either after treatment with induction chemotherapy or after high-dose therapy.
journal_name
Haematologicajournal_title
Haematologicaauthors
Schilthuizen C,Broyl A,van der Holt B,de Knegt Y,Lokhorst H,Sonneveld Pdoi
10.3324/haematol.10618subject
Has Abstractpub_date
2007-02-01 00:00:00pages
277-8issue
2eissn
0390-6078issn
1592-8721journal_volume
92pub_type
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