Abstract:
:Depolarization of an excitable membrane has a dual effect; excitatory in that it causes rapid opening of calcium and/or sodium channels but inhibitory in that it also causes those channels to inactivate. We considered whether apparently paradoxical or dual behavior might be exhibited by excitatory and inhibitory synaptic inputs. We used the classic Hodgkin-Huxley model for voltage-gated channels plus leakage channels of appropriate selectivity for ligand-gated postsynaptic channels. We summarize a model cell's behavior by calculating elicited firing frequency as a function of reversal potential and conductance of summed synaptic inputs, using stability theory and direct simulations. Dual behavior is elicited in the model with reasonable densities of ligand-gated channels. Thus a particular synaptic input to a neuron may be either excitatory or inhibitory depending on simultaneous activity of other synaptic inputs to the cell. This input-output map may give rise to biologically realistic and rich behaviors as an element of computed neural networks, and still be computationally tractable.
journal_name
Biol Cybernjournal_title
Biological cyberneticsauthors
Davenport R,Jakobsson E,Gerber Bdoi
10.1007/BF00197289subject
Has Abstractpub_date
1991-01-01 00:00:00pages
47-53issue
1eissn
0340-1200issn
1432-0770journal_volume
65pub_type
杂志文章abstract::A pacemaker cell pair model and the dynamic interaction between the two pacemaker cells is described in this paper. It is an extension of our single pacemaker cell model, in which we studied its response to repetitive external depolarization stimulations. This model is a simple model based on the two most important fu...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220050460
更新日期:1998-07-01 00:00:00
abstract::The peripheral auditory system of lizards has been extensively studied, because of its remarkable directionality. In this paper, we review the research that has been performed on this system using a biorobotic approach. The various robotic implementations developed to date, both wheeled and legged, of the auditory mod...
journal_title:Biological cybernetics
pub_type: 杂志文章,评审
doi:10.1007/s00422-016-0701-y
更新日期:2016-10-01 00:00:00
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journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00337450
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abstract::The present report presents an attempt to define the physiological parameter used to describe "voice tremor" in psychological stress evaluating machines, and to find its sources. This parameter was found to be a low frequency (5-20 Hz) random process which frequency modulates the vocal cord waveform and (independently...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00340063
更新日期:1983-01-01 00:00:00
abstract::We offer a hypothesis on the organization of multi-effector motor synergies and illustrate it with the task of force production with a set of fingers. A physical metaphor, a leaking bucket, is analyzed to demonstrate that an inanimate structure can show apparent error compensation among its elements. A neural model is...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-005-0548-0
更新日期:2005-03-01 00:00:00
abstract::The impact of dendritic geometry on somatopetal transfer of the current generated by steady uniform activation of excitatory synaptic conductance distributed over passive, or active (Hodgkin-Huxley type), dendrites was studied in simulated neurons. Such tonic activation was delivered to the uniform dendrite and to the...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220050473
更新日期:1998-09-01 00:00:00
abstract::Beck (1972, 1973) hypothesized that textural segmentation occurs strongly on the basis of simple properties such as brightness, color, size, and the slopes of contours and lines of the elemental descriptors of a texture or textural elements. The experiment reported supports the hypothesis that specific stimulus featur...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00344396
更新日期:1983-01-01 00:00:00
abstract::Highly-interconnected networks of nonlinear analog neurons are shown to be extremely effective in computing. The networks can rapidly provide a collectively-computed solution (a digital output) to a problem on the basis of analog input information. The problems to be solved must be formulated in terms of desired optim...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00339943
更新日期:1985-01-01 00:00:00
abstract::The order parameter equation for the relative phase of correlated hand movements, derived in a previous paper by Haken et al. (1985), is extended to a time-dependent stochastic differential equation. Its solutions are determined close to stationary points and for the transition region. Remarkably good agreement betwee...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00336995
更新日期:1986-01-01 00:00:00
abstract::We study weakly connected networks of neural oscillators near multiple Andronov-Hopf bifurcation points. We analyze relationships between synaptic organizations (anatomy) of the networks and their dynamical properties (function). Our principal assumptions are: (1) Each neural oscillator comprises two populations of ne...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220050279
更新日期:1996-08-01 00:00:00
abstract::Estimating the behavior of a network of neurons requires accurate models of the individual neurons along with accurate characterizations of the connections among them. Whereas for a single cell, measurements of the intracellular voltage are technically feasible and sufficient to characterize a useful model of its beha...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-014-0601-y
更新日期:2014-06-01 00:00:00
abstract::Motion control of musculoskeletal systems for functional electrical stimulation (FES) is a challenging problem due to the inherent complexity of the systems. These include being highly nonlinear, strongly coupled, time-varying, time-delayed, and redundant. The redundancy in particular makes it difficult to find an inv...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-008-0258-5
更新日期:2008-12-01 00:00:00
abstract::Stochastic resonance is demonstrated in a simple energy detector model, as a non-monotonic relationship between signal-to-noise ratio and detection of a sinusoid signal in bandpass-limited Gaussian noise. The behaviour of the model detecting signals of various intensities and signal-to-noise ratios was investigated. S...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220000176
更新日期:2000-11-01 00:00:00
abstract::The human optokinetic response to a horizontally moving stripped pattern surrounding the subject was investigated under quasi-open and closed loop conditions. Open loop conditions were produced by the addition of an external signal from measured slow phase eye velocity to stripe velocity. A comparison of open and clos...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00453373
更新日期:1981-01-01 00:00:00
abstract::A neural network model of the mechanism of selective attention in visual pattern recognition is proposed and simulated on a digital computer. When a complex figure consisting of two patterns or more is presented to the model, it is segmented into individual patterns, and each pattern is recognized separately. Even if ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00363973
更新日期:1986-01-01 00:00:00
abstract::The evolutionary transition from water to land required new locomotor modes and corresponding adjustments of the spinal "central pattern generators" for locomotion. Salamanders resemble the first terrestrial tetrapods and represent a key animal for the study of these changes. Based on recent physiological data from sa...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-012-0538-y
更新日期:2013-10-01 00:00:00
abstract::A signal-tuned approach has been recently introduced for modeling stimulus-dependent cortical receptive fields. The approach is based on signal-tuned Gabor functions, which are Gaussian-modulated sinusoids whose parameters are obtained from a "tuning" signal. Given a stimulus to a cell, it is taken as the tuning signa...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-015-0653-7
更新日期:2015-10-01 00:00:00
abstract::An important step in visual processing is the segregation of objects in a visual scene from one another and from the embedding background. According to current theories of visual neuroscience, the different features of a particular object are represented by cells which are spatially distributed across multiple visual ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00203232
更新日期:1994-01-01 00:00:00
abstract::Nonlinear oscillators are usually utilized by bionic scientists for establishing central pattern generator models for imitating rhythmic motions by bionic scientists. In the natural word, many rhythmic motions possess asymmetric time ratios, which means that the forward and the backward motions of an oscillating proce...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-018-0746-1
更新日期:2018-06-01 00:00:00
abstract::With regular trains of stimuli at a high frequency, the contribution of each stimulus to the force generated over time declines from the second to about the tenth stimulus, but then begins to increase again. This late increase is referred to as tetanic potentiation in analogy with the post-tetanic potentiation of the ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00340074
更新日期:1982-01-01 00:00:00
abstract::The correspondence between afferent discharges and sinusoidal length modulations (0.2--10 cps, under 10% of the natural length variations) was studied in isolated fast-adapting stretch receptor organs (FAO) of crayfish, largely using average displays of rate vs. length (or derivatives) along the cycle. Rate modulation...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00336926
更新日期:1983-01-01 00:00:00
abstract::This paper deals with the problem of representing and generating unconstrained aiming movements of a limb by means of a neural network architecture. The network produced time trajectories of a limb from a starting posture toward targets specified by sensory stimuli. Thus the network performed a sensory-motor transform...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF02414903
更新日期:1989-01-01 00:00:00
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journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-014-0621-7
更新日期:2014-12-01 00:00:00
abstract::This paper develops a novel control system for functional electrical stimulation (FES) locomotion, which aims to generate normal locomotion for paraplegics via FES. It explores the possibility of applying ideas from biology to engineering. The neural control mechanism of the biological motor system, the central patter...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-006-0107-3
更新日期:2007-01-01 00:00:00
abstract::Within a linear field approach, an architectural model for simple cell direction selectivity in the visual cortex is proposed. The origin of direction selectivity is related to recurrent intracortical interactions with a spatially asymmetric character along the axis of stimulus motion. No explicit asymmetric temporal ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220050515
更新日期:1999-03-01 00:00:00
abstract::For over 75 years it has been clear that the number of spikes in a neural response is an important part of the neuronal code. Starting as early as the 1950's with MacKay and McCullough, there has been speculation over whether each spike and its exact time of occurrence carry information. Although it is obvious that th...
journal_title:Biological cybernetics
pub_type: 杂志文章,评审
doi:10.1007/s00422-009-0321-x
更新日期:2009-06-01 00:00:00
abstract::The vestibuloocular reflex and other oculomotor functions are subserved by populations of neurons operating in parallel. This distributed aspect of the system's organization has been largely ignored in previous block diagram models. Neurons that transmit oculomotor signals, such as those in the vestibular nucleus (VN)...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00204592
更新日期:1989-01-01 00:00:00
abstract::The visual system is constantly confronted with the problem of integrating local signals into more global arrangements. This arises from the nature of early cell responses, whether they signal localized measures of luminance, motion, retinal position differences, or discontinuities. Consequently, from sparse, local me...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220100258
更新日期:2001-11-01 00:00:00
abstract::To investigate the dynamic effects of external forces on the displacement of the otolith membrane and subsequent neuronal responses of otoliths, we performed numerical analyses of otolith membrane displacements. In these studies we included the full geometry of the human otolith maculae, including their 3D curvature. ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-003-0456-0
更新日期:2004-03-01 00:00:00
abstract::This article compiles an expose of Valentino Braitenberg's singular view on neuroanatomy and neuroscience. The review emphasizes his topologically informed work on neuroanatomy and his dialectics of brain-based explanations of motor behavior. Some of his early ideas on topologically informed neuroanatomy are presented...
journal_title:Biological cybernetics
pub_type: 传,历史文章,杂志文章,评审
doi:10.1007/s00422-012-0533-3
更新日期:2014-10-01 00:00:00