Contraction-induced interleukin-6 transcription in rat slow-type muscle is partly dependent on calcineurin activation.

abstract：:Construction of artificial organs and tissues by tissue engineering is strongly dependent on the availability of viable cells. For that reason, the viability and the physiological status of cells kept in culture must be evaluated before the cells can be used for clinical purposes. In this work, we determined the viabi...

journal_title：Journal of cellular physiology

authors： Alaminos M,Sanchez-Quevedo MC,Muñoz-Avila JI,García JM,Crespo PV,González-Andrades M,Campos A

更新日期：2007-06-01 00:00:00

abstract：:A novel, serum albumin-binding glycoprotein of molecular weight (mw) 43,000 (43K protein) was initially purified from the culture medium of bovine aortic endothelial (BAE) cells (Sage, H., Johnson, C., and Bornstein, P., J. Biol. Chem. 259:3993-4007, 1984). Its secretion by normal mesenchymal cells and by transformed ...

journal_title：Journal of cellular physiology

authors： Sage H,Tupper J,Bramson R

更新日期：1986-06-01 00:00:00

abstract：:Factors inhibiting cell growth have been isolated from different cell types. However, little information is available concerning their mode of action. A novel growth inhibitory factor of 45 kDa (IDF45) was recently purified to homogeneity from medium conditioned by 3T3 cells. This molecule was able to inhibit DNA synt...

journal_title：Journal of cellular physiology

authors： Delbe J,Villaudy J,Blat C,Desauty G,Golde A,Harel L

更新日期：1990-02-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family of cytokines are involved in diverse physiological processes. Although TGF-β is known to play multiple roles in the mammalian central nervous system (CNS), its role in neuronal development has not been explored. We have studied the effects of TGF-β1 on the ele...

journal_title：Journal of cellular physiology

authors： Zhuang JL,Wang CY,Zhou MH,Duan KZ,Mei YA

更新日期：2012-01-01 00:00:00

abstract：:Concanavalin A (ConA)-induced hepatitis is an experimental model of human autoimmune hepatitis induced in rodents by i.v. injection of Con A. The disease is characterized by increase in serum levels of transaminases and massive immune infiltration of the livers. Type 1, type 2, and type 17 cytokines play a pathogenic ...

journal_title：Journal of cellular physiology

authors： Mangano K,Cavalli E,Mammana S,Basile MS,Caltabiano R,Pesce A,Puleo S,Atanasov AG,Magro G,Nicoletti F,Fagone P

更新日期：2018-05-01 00:00:00

abstract：:A mutant of BHK cells (ts422E) temperature-sensitive for processing 32S rRNA to 28S rRNA (Toniolo et al., '73) also loses the ability to synthesize polyamines and 5.8S rRNA when shifted to the non-permissive temperature (39 degrees). The activity of several enzymes not involved with polyamine synthesis, methylation of...

journal_title：Journal of cellular physiology

authors： Levin EG,Clark JL

更新日期：1979-12-01 00:00:00

abstract：:There is compelling in vitro and in vivo evidence to implicate mast cells in the development of fibrosis. However, an important question remains as to the mechanisms by which mast cells mediate fibrosis. Recent evidence from our laboratory (Gruber et al., 1997, J. Immunol. , 158:2310-2317) has revealed that tryptase, ...

journal_title：Journal of cellular physiology

authors： Zhang J,Gruber BL,Marchese MJ,Zucker S,Schwartz LB,Kew RR

更新日期：1999-11-01 00:00:00

abstract：:Loss of TSC1 function, a crucial negative regulator of mTOR signaling, is a common alteration in bladder cancer. Mutations in other members of the PI3K pathway, leading to mTOR activation, are also found in bladder cancer. This provides rationale for targeting mTOR for treatment of bladder cancer characterized by TSC1...

journal_title：Journal of cellular physiology

authors： Alayev A,Salamon RS,Schwartz NS,Berman AY,Wiener SL,Holz MK

更新日期：2017-02-01 00:00:00

abstract：:It is well known that cell proliferation (and hence, DNA synthesis) declines in human diploid fibroblast-like cells with increasing passage number. It is not clear whether DNA synthesis declines in the remaining cells that are still actively proliferating. Estimations of cell kinetic parameters permitted extrapolation...

journal_title：Journal of cellular physiology

authors： Collins JM,Chu AK

更新日期：1985-07-01 00:00:00

abstract：:The effects of the glucose supply on growth and metabolism of an SP2/0 derived recombinant myeloma cell line were studied in chemostat culture during growth on IMDM medium at a fixed dilution rate of 0.032 h-1. Lowering of the feed medium glucose concentration from 25.0 to 1.4 mmol/L resulted in a decrease of steady-s...

journal_title：Journal of cellular physiology

authors： Meijer JJ,van Dijken JP

更新日期：1995-02-01 00:00:00

abstract：:We reported that Disabled-2 (Dab2) is located at the apical membrane in suckling rat intestine. Here, we discovered that, in colon of suckling and adult mouse and of adult human, Dab2 is only at lateral crypt cell membrane and colocalized with E-cadherin. Dab2 depletion in Caco-2 cells led to E-cadherin internalizatio...

journal_title：Journal of cellular physiology

authors： Vazquez-Carretero MD,García-Miranda P,Balda MS,Matter K,Ilundáin AA,Peral MJ

更新日期：2021-02-01 00:00:00

abstract：:This study establishes a causal link between the limitation of myofibre transitions and modulation of calcineurin activity, during different exercise paradigms. We have designed a new swimming-based training protocol in order to draw a comparison between a high frequency and amplitude exercise (swimming) and low frequ...

journal_title：Journal of cellular physiology

authors： Grondard C,Biondi O,Pariset C,Lopes P,Deforges S,Lécolle S,Gaspera BD,Gallien CL,Chanoine C,Charbonnier F

更新日期：2008-01-01 00:00:00

abstract：:The expression of parathyroid hormone-related protein (PTHrP) was studied in a range of cell cultures representative of the osteoblast lineage and in rat calvarial sections. Primary newborn rat calvarial cells, a rat preosteoblastic cell line (UMR 201), a mouse stromal cell line (ST 2), a mouse calvaria-derived osteob...

journal_title：Journal of cellular physiology

authors： Suda N,Gillespie MT,Traianedes K,Zhou H,Ho PW,Hards DK,Allan EH,Martin TJ,Moseley JM

更新日期：1996-01-01 00:00:00

abstract：:The increased levels of c-Myc protein observed previously in an ovarian carcinoma cell line stably transfected to express HER2 has suggested a role for the HER2 pathway in c-Myc expression. Analysis of HER2-transfected cells stimulated with heregulin beta1 (HRG) revealed increased c-Myc protein levels but not a corres...

journal_title：Journal of cellular physiology

authors： Galmozzi E,Casalini P,Iorio MV,Casati B,Olgiati C,Ménard S

更新日期：2004-07-01 00:00:00

abstract：:Zinc finger E-box binding homeobox 1 (ZEB1), an important transcription factor belonging to the ZEB family, plays a crucial role in regulating gene expression required for both normal physiological and pathological processes. Accumulating evidence has shown that ZEB1 participates in the initiation and progression of a...

journal_title：Journal of cellular physiology

authors： Li H,Zou J,Yu XH,Ou X,Tang CK

更新日期：2020-12-04 00:00:00

abstract：:The toxicity of cationic fluorescent dye, rhodamine 123, towards a number of independently established cell lines from three different species, namely human, mouse, and Chinese hamster, has been examined. All of the cell lines from any one species that were examined were found to exhibit similar sensitivities towards ...

journal_title：Journal of cellular physiology

authors： Gupta RS,Dudani AK

更新日期：1987-03-01 00:00:00

abstract：:Tobacco smoking is associated with many diseases. Addiction is of the most notorious tobacco-related syndrome and is mainly attributed to nicotine. In this study, we employed Caenorhabditis elegans as a biological model to systemically investigate the effect of chronic nicotine exposure on microRNA (miRNA) expression ...

journal_title：Journal of cellular physiology

authors： Taki FA,Pan X,Zhang B

更新日期：2014-01-01 00:00:00

abstract：:Butyrate and acetate are bacterial metabolites present in the large intestine lumen. Although butyrate is well known to inhibit the in vitro proliferation of human colon carcinoma cells in a process involving the hyperacetylation of specific nuclear histones, little is known about the possible link between butyrate me...

journal_title：Journal of cellular physiology

authors： Andriamihaja M,Chaumontet C,Tome D,Blachier F

更新日期：2009-01-01 00:00:00

abstract：:The effect of transforming growth factor-beta 1 (TGF-beta 1) on collagen biosynthesis was investigated in confluent primary monolayer cultures of rabbit articular chondrocytes (RAC). Exposure to TGF-beta (0.1, 1, and 10 ng/ml) in serum-free medium caused a dose- and time-dependent stimulation of collagen biosynthesis ...

journal_title：Journal of cellular physiology

authors： Galéra P,Vivien D,Pronost S,Bonaventure J,Rédini F,Loyau G,Pujol JP

更新日期：1992-12-01 00:00:00

abstract：:This study describes the alterations induced by Interleukin-1 alpha and -beta (IL-1 alpha and IL-1 beta) on fibroblast-synthesized extracellular matrix. Fibroblasts were grown between pieces of dentin or in collagen-coated Terasaki wells for 3 or 6-9 weeks to create 3-dimensional cell-containing matrices constituted p...

journal_title：Journal of cellular physiology

authors： Qwarnström EE,MacFarlane SA,Page RC

更新日期：1989-06-01 00:00:00

abstract：:Myocardin is a transcriptional co-activator of serum response factor (SRF) and can be degraded through ubiquitin-proteasome system. Our preliminary studies unexpectedly revealed that accumulation of myocardin in response to proteasome inhibition by MG132 or lactacystin resulted in decrease of transcriptional activity ...

journal_title：Journal of cellular physiology

authors： Yin H,Jiang Y,Li H,Li J,Gui Y,Zheng XL

更新日期：2011-07-01 00:00:00

abstract：:Hair follicle stem cells (HFSCs) are able to differentiate into neurons and glial cells. Distinct microRNAs (miRNAs) regulate the proliferation and differentiation of HFSCs. However, the exact role of miR-124 in the neural differentiation of HFSCs has not been elucidated. HFSCs were isolated from mouse whisker follicl...

journal_title：Journal of cellular physiology

authors： Mokabber H,Najafzadeh N,Mohammadzadeh Vardin M

更新日期：2019-06-01 00:00:00

abstract：:The trabecular meshwork (TM) is a specialized tissue located at the chamber angle of the eye next to the cornea. This tissue is believed to be responsible for regulation of the aqueous humor outflow and control of the intraocular pressure (IOP). Alterations in functions of the TM may lead to IOP elevation and developm...

journal_title：Journal of cellular physiology

authors： Wentz-Hunter K,Ueda J,Shimizu N,Yue BY

更新日期：2002-01-01 00:00:00

abstract：:Norepinephrine (NE) produced a dose-dependent inhibition of 125I-epidermal growth factor (EGF) binding to adult rat hepatocytes in primary culture. This effect was maximal after 1 hr of incubation with NE and could be blocked by the presence of an alpha 1-specific adrenergic receptor antagonist. The inhibition of bind...

journal_title：Journal of cellular physiology

authors： Cruise JL,Cotecchia S,Michalopoulos G

更新日期：1986-04-01 00:00:00

abstract：:Growth-contingent alterations in potassium and sodium fluxes, ouabain binding, and potassium ion content were examined following serum stimulation of quiescent, density-inhibited chicken embryo fibroblasts. Serum stimulation resulted in very rapid 1.5- to 1.8-fold increases in ouabain-sensitive potassium influx and le...

journal_title：Journal of cellular physiology

authors： Johnson MA,Weber MJ

更新日期：1980-05-01 00:00:00

abstract：:The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progester...

journal_title：Journal of cellular physiology

authors： Sirotkin AV,Ovcharenko D,Grossmann R,Lauková M,Mlyncek M

更新日期：2009-05-01 00:00:00

abstract：:This study is carried out to elucidate the role of long noncoding RNAs (lncRNAs) MT1JP in proliferation, invasion, migration, and apoptosis of glioma cells through the regulation of PTEN/Akt signaling pathway. The expression of MT1JP in 80 normal brain tissues and 138 glioma tissues, as well as glioma cell lines, was ...

journal_title：Journal of cellular physiology

authors： Zhang Y,Sui R,Chen Y,Liang H,Shi J,Piao H

更新日期：2019-11-01 00:00:00

abstract：:In this study, we examine whether an anti-inflammatory thiourea derivative, compound #326, actions on ion channels. The effects of compound #326 on Ca2+ -activated K+ channels were evaluated by patch-clamp recordings obtained in cell-attached, inside-out or whole-cell configuration. In pituitary GH3 cells, compound #3...

journal_title：Journal of cellular physiology

authors： Wu SN,Chern JH,Shen S,Chen HH,Hsu YT,Lee CC,Chan MH,Lai MC,Shie FS

更新日期：2017-12-01 00:00:00

abstract：:Osteopontin (OPN) is a major non-collagenous bone matrix protein implicated in the regulation of cell function. Although OPN is rich in the cementum of the tooth, the significance of OPN in this tissue is not understood. Tooth root resorption is the most frequent complication of orthodontic tooth movement (TM). The ob...

journal_title：Journal of cellular physiology

authors： Chung CJ,Soma K,Rittling SR,Denhardt DT,Hayata T,Nakashima K,Ezura Y,Noda M

更新日期：2008-03-01 00:00:00

abstract：:3-Hydroxy 3-methylglutaryl coenzyme A reductase (HMG-CoAR) is the key and rate-limiting enzyme of cholesterol biosynthetic pathway. Although HMG-CoAR activity has already been related to the differentiation of some cellular lines there are no studies that analyze the role of HMG-CoAR, and the pathway it is involved wi...

journal_title：Journal of cellular physiology

authors： Martini C,Trapani L,Narciso L,Marino M,Trentalance A,Pallottini V

更新日期：2009-08-01 00:00:00