A comparative review of charged particle microbeam facilities.

Abstract:

:At the low doses (and low dose rates) relevant to environmental and occupational radiation exposure (0-50 mSv), which are of practical concern for radiation protection, very few cells in the human organism experience more than one traversal by densely ionising particles in their lifetime, the intervals between the tracks, if any, typically being months or years. The biological effects of exactly one particle are not well known and cannot be simulated in vitro by conventional broad-beam exposures, due to the random Poisson distribution of tracks. Charged particle microbeam facilities are a unique tool that allows targeting of single cells and analysis of the induced damage on a cell-by-cell basis. In the past few years, many charged particle microbeam facilities for radiobiology have come into operation or are under development worldwide. Different experimental designs have been adopted at various laboratories regarding the achievement of micrometre (or sub-micrometre) ion beam size, by mechanical collimation or focusing, particle detection, and cell recognition and positioning systems. The different approaches are reviewed and discussed in this paper.

journal_name

Radiat Prot Dosimetry

authors

Gerardi S

doi

10.1093/rpd/ncl444

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

285-91

issue

1-4

eissn

0144-8420

issn

1742-3406

pii

ncl444

journal_volume

122

pub_type

杂志文章,评审
  • Radiation protection at low energy proton accelerators.

    abstract::A sample is provided of the radiological safety issues particular to low energy proton accelerators. 'Low' energy in this context is taken to mean proton energies of less than about 1 GeV. Many of the radiation issues are common to all particle accelerators. Here, those issues are addressed that may require perhaps no...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.rpd.a006619

    authors: Moritz LE

    更新日期:2001-01-01 00:00:00

  • Thermoluminescence properties of LiMgF3 doped with Ce, Er and Dy.

    abstract::The main dosimetric properties are reported of a new perovskite, LiMgF3, doped with Ce, Er and Dy impurities. An annealing temperature of 400 degrees C for one hour is necessary to erase any previous signal and to stabilise its sensitivity. A readout up to 450 degrees C gives the same result. The glow curve structure ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.rpd.a005858

    authors: Kitis G,Furetta C,Sanipoli C

    更新日期:2002-01-01 00:00:00

  • A software tool for increased efficiency in observer performance studies in radiology.

    abstract::Observer performance studies are time-consuming tasks, both for the participating observers and for the scientists collecting and analysing the data. A possible way to optimise such studies is to perform them in a completely digital environment. A software tool-ViewDEX (Viewer for Digital Evaluation of X-ray images)-h...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nch550

    authors: Börjesson S,Håkansson M,Båth M,Kheddache S,Svensson S,Tingberg A,Grahn A,Ruschin M,Hemdal B,Mattsson S,Månsson LG

    更新日期:2005-01-01 00:00:00

  • ORGAN ABSORBED DOSE ESTIMATION REFLECTING SPECIFIC ORGAN MASSES WITH SIMPLE SCALING OF REFERENCE DOSES USING THE ORGAN MASSES.

    abstract::Estimating organ absorbed doses in consideration of person-specific parameters is important for radiation protection in diagnostic nuclear medicine. This study proposes a straightforward method for estimating the organ dose that reflects a specific organ mass by scaling the reference organ dose using the inverse ratio...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncaa058

    authors: Manabe K,Koyama S

    更新日期:2020-07-24 00:00:00

  • Energy responses of the LiF series TL pellets to high-energy photons in the energy range from 1.25 to 21 MV.

    abstract::The energy responses for the KLT-300(LiF:Mg,Cu,Na,Si, Korea), GR-200(LiF:Mg,Cu,P, China) and MCP-N(LiF:Mg,Cu,P, Poland) thermoluminescence(TL) pellets were studied for a photon radiation with energies from 1.25 MeV(60Co) to 21 MV (Microtron) to verify the usefulness of the calibration for the radiotherapy beams. The I...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci627

    authors: Kim JL,Lee JI,Ji YH,Kim BH,Kim JS,Chang SY

    更新日期:2006-01-01 00:00:00

  • A new method for determining HT deposition velocity and dependence of the velocity on environmental factors.

    abstract::A new method was developed to determine HT deposition velocity and to investigate how environmental factors affect the deposition processes including the diffusion into soil and the biochemical conversion by microorganisms to HTO in soil. This method, using a chamber and two tritium samplers, enables determination of ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.rpd.a006435

    authors: Koarashi J,Amano H,Andoh M,Iida T,Koma T

    更新日期:2001-01-01 00:00:00

  • THE CHALLENGE IN USING THE RETROSPECTIVE ASSESSMENT OF RESIDENTIAL RADON CONCENTRATION.

    abstract::In the present study, the contemporary indoor radon activity concentration and the surface-deposited 210Po activity were measured in 65 Romanian dwellings. The activity of trapped 210Po on the glass surface was measured using the (CR-LR) difference technique. The retrospective radon activity concentration estimated on...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncy095

    authors: Dicu T,Burghele BD,Lupulescu D,Cucos A

    更新日期:2018-09-01 00:00:00

  • Measured proton sensitivities of bubble detectors.

    abstract::The neutron dose equivalent in aircraft is measured using commercial bubble detectors, but at high altitudes there are not only neutrons but also protons. Bubble detectors have been used because they are considered not to be sensitive to protons, but this has been the subject of only a few studies. In this study, by i...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nch330

    authors: Takada M,Kitamura H,Koi T,Nakamura T,Fujitaka K

    更新日期:2004-01-01 00:00:00

  • IDACstar: A MCNP Application to Perform Realistic Dose Estimations from Internal or External Contamination of Radiopharmaceuticals.

    abstract::A Monte Carlo-based stand-alone program, IDACstar (Internal Dose Assessment by Computer), was developed, dedicated to perform radiation dose calculations using complex voxel simulations. To test the program, two irradiation situations were simulated, one hypothetical contamination case with 600 MBq of 99mTc and one ex...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncw221

    authors: Ören Ü,Hiller M,Andersson M

    更新日期:2017-04-28 00:00:00

  • The TRADE experiment: shielding calculations for the building hosting the subcritical system.

    abstract::The TRADE project (TRiga Accelerator Driven Experiment), to be performed at the existing TRIGA reactor at ENEA Casaccia, has been proposed as a validation of the accelerator-driven system (ADS) concept. TRADE will be the first experiment in which the three main components of an ADS--the accelerator, spallation target ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci219

    authors: Burn KW,Carta M,Casalini L,Kadi Y,Monti S,Nava E,Palomba M,Petrovich C,Picardi L,Rubbia C,Troiani F

    更新日期:2005-01-01 00:00:00

  • EURADOS coordinated action on research, quality assurance and training of internal dose assessments.

    abstract::EURADOS working group on 'Internal Dosimetry (WG7)' represents a frame to develop activities in the field of internal exposures as coordinated actions on quality assurance (QA), research and training. The main tasks to carry out are the update of the IDEAS Guidelines as a reference document for the internal dosimetry ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncq435

    authors: Lopez MA,Balásházy I,Bérard P,Blanchardon E,Breustedt B,Broggio D,Castellani CM,Franck D,Giussani A,Hurtgen C,James AC,Klein W,Kramer GH,Li WB,Marsh JW,Malatova I,Nosske D,Oeh U,Pan G,Puncher M,Peixoto Telles P,

    更新日期:2011-03-01 00:00:00

  • On the use of LiF TLD-600 in neutron-gamma mixed fields.

    abstract::A new procedure allowing the separate estimation of neutron and gamma dose in mixed radiation fields has been developed in our laboratory. In this communication, a description of the main features of the discrimination procedure and some preliminary results obtained by its use are presented. The procedure is based on ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm210

    authors: Delgado A,Muñiz JL,Gómez Ros JM,Romero AM,Rodríguez R

    更新日期:2007-01-01 00:00:00

  • Shielding design of a brachytherapy unit at the Korle Bu teaching hospital in Ghana: comparison of theoretical calculations and experimental study.

    abstract::A theoretical study was carried out to re-evaluate the integrity of the biological shielding of (137)Cs brachytherapy unit at the Korle Bu Teaching Hospital, Ghana, and the results were verified by measurement of the dose rates at selected locations. The primary objective was to determine the current state of protecti...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncq001

    authors: Arwui CC,Schandorf C,Nani K,Darko EO,Deatanyah P

    更新日期:2010-06-01 00:00:00

  • Soil gas radon measurements in a region of the Bohemian Massif: investigations in the framework of an Austrian pilot study.

    abstract::Soil gas radon measurements are carried out in a pilot study in three municipalities in Upper Austria. The selected municipalities are characterised by a high radon potential. Sixty measuring sites--well distributed over the region and over the different geological areas--were selected. Additionally, the permeability ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncr089

    authors: Seidel C,Baumgartner A,Ringer W,Gräser J,Friedmann H,Kaineder H,Maringer FJ

    更新日期:2011-05-01 00:00:00

  • Dose conversion of radon exposure according to new epidemiological findings.

    abstract::In 1993, ICRP-65 recommended that dose conversion of radon exposure should be based on the comparison of detriments between radon exposure and effective dose. The lifetime detriment from the radon exposure was projected according to the epidemiological studies of uranium miners then available. The projection model (GS...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncn117

    authors: Tomasek L,Rogel A,Laurier D,Tirmarche M

    更新日期:2008-01-01 00:00:00

  • Characterisation of non-constant background in counting measurements.

    abstract::A 'moving-target' method for characterising background in a counting measurement in which the instantaneous background count rate is a function of time, rather than being fixed, is proposed. This model treats the average Poisson mean in observation period P as coming from a gamma distribution with parameters αP and βP...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncu297

    authors: Klumpp J,Miller G,Brandl A

    更新日期:2015-04-01 00:00:00

  • Issues, considerations and recommendations on emergency preparedness for vulnerable population groups.

    abstract::The Workshop on Emergency Preparedness for Vulnerable Population Groups was held on 2 and 3 March 2009 in Ottawa, ON, Canada. The purpose of the workshop was to enhance communications within the emergency community response network and to identify the needs and gaps of emergency preparedness against chemical, biologic...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncp083

    authors: Chen J,Wilkinson D,Richardson RB,Waruszynski B

    更新日期:2009-06-01 00:00:00

  • Assessment of patient organ doses and effective doses using the VIP-Man adult male phantom for selected cone-beam CT imaging procedures during image guided radiation therapy.

    abstract::A Monte Carlo based computational procedure for determining organ doses and effective doses has been described for two procedures used in newly developed image-guided radiation treatment: kilovoltage cone-beam computed tomography (kV CBCT) and mega-voltage computed tomography (MV CBCT). A whole-body patient computatio...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncn200

    authors: Gu J,Bednarz B,Xu XG,Jiang SB

    更新日期:2008-01-01 00:00:00

  • ESTIMATION OF ORGAN DOSES AMONG DIAGNOSTIC MEDICAL RADIATION WORKERS IN SOUTH KOREA.

    abstract::This study aimed to estimate the radiation organ doses from occupational exposure in 94 396 Korean medical radiation workers. Data on badge doses (i.e. personal dose equivalent at 10 mm) between 1996 and 2011 obtained from a national dosimetry registry, survey data from 2012 to 2013, and organ dose conversion coeffici...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncx239

    authors: Choi Y,Shil Cha E,Jin Bang Y,Ko S,Ha M,Lee C,Jin Lee W

    更新日期:2018-04-01 00:00:00

  • VALIDATION OF A BEAMNRC MONTE CARLO SIMULATION OF A BROAD BEAM DIAGNOSTIC X-RAY UNIT.

    abstract::A BEAMnrc Monte Carlo simulation of a diagnostic X-ray unit in a broad beam geometry intended for the derivation of effective linear attenuation coefficients was validated against measurements made on the X-ray unit on which the simulation was based. The validation process assessed the size of the beam, the first and ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncz032

    authors: Worrall M,Sutton DG

    更新日期:2019-12-31 00:00:00

  • Maximum likelihood estimates of mean and variance of occupation radiation doses subjected to minimum detection levels.

    abstract::Data collection and its analysis in the field of nuclear safety is an important task in the sense that it powers the improvement of safety as well as reliability of the plant. Thus, occupational exposure data analysis is presented to measure the safety or reliability of radiation protection of a given facility. It als...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm483

    authors: Datta D,Singh S,Johnson BE,Kushwaha HS

    更新日期:2008-01-01 00:00:00

  • Secondary neutron doses in proton therapy treatments of ocular melanoma and craniopharyngioma.

    abstract::Monte Carlo simulations were used to assess secondary neutron doses received by patients treated with proton therapy for ocular melanoma and craniopharyngioma. MCNPX calculations of out-of-field doses were done for ∼20 different organs considering realistic treatment plans and using computational phantoms representati...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nct283

    authors: Farah J,Sayah R,Martinetti F,Donadille L,Lacoste V,Hérault J,Delacroix S,Nauraye C,Vabre I,Lee C,Bolch WE,Clairand I

    更新日期:2014-10-01 00:00:00

  • Shielding design of the ITER NBI duct for nuclear and bremsstrahlung radiation.

    abstract::Three-dimensional Monte Carlo shielding analyses are conducted on the ITER Neutral Beam Injection (NBI) duct for the nuclear and bremsstrahlung radiation. The detailed distribution is evaluated about the nuclear heating rate and surface heat load of the NBI duct wall by the neutron and photon transport calculation. Th...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci195

    authors: Sato S,Iida H,Yamauchi M,Nishitani T

    更新日期:2005-01-01 00:00:00

  • Discrimination between natural and other gamma ray sources from environmental gamma ray dose rate monitoring data.

    abstract::In this study, a method to discriminate between natural and other γ-ray sources from environmental γ-ray dose rate monitoring data was developed, and it was successfully applied to actual monitoring data around nuclear facilities. The environmental dose rate is generally monitored by NaI(Tl) detector systems in the lo...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncv265

    authors: Kumagai K,Ookubo H,Kimura H

    更新日期:2015-11-01 00:00:00

  • Quality assurance (QA) procedures for software: evaluation of an ADC quality system.

    abstract::Image viewing and processing software in computed radiography manipulates image contrast in such a way that all relevant image features are rendered to an appropriate degree of visibility, and improves image quality using enhancement algorithms. The purpose of this study was to investigate procedures for the quality a...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci742

    authors: Efstathopoulos EP,Benekos O,Molfetas M,Charou E,Kottou S,Argentos S,Kelekis NL

    更新日期:2005-01-01 00:00:00

  • Bayesian approach for quantifying the uncertainty of neutron doses derived from spectrometric measurements.

    abstract::Bayesian methods provide a unified framework for combining information in the presence of uncertainty. All uncertainties that enter into the description of a measurement are modelled using probability distributions, and these are handled according to the rules of probability theory, ensuring that the approach is free ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncl096

    authors: Reginatto M

    更新日期:2006-01-01 00:00:00

  • Nodule detection in digital chest radiography: effect of anatomical noise.

    abstract::The image background resulting from imaged anatomy can be divided into those components that are meaningful to the observers, in the sense that they are recognised as separate structures, and those that are not. These latter components (reffered to as anatomical noise) can be removed using a method developed within th...

    journal_title:Radiation protection dosimetry

    pub_type: 临床试验,杂志文章

    doi:10.1093/rpd/nch526

    authors: Båth M,Håkansson M,Börjesson S,Hoeschen C,Tischenko O,Kheddache S,Vikgren J,Månsson LG

    更新日期:2005-01-01 00:00:00

  • A review of the properties of the dosimetric systems and the quality assurance programmes of 48 dosimetric services in the European Union and Switzerland.

    abstract::This paper summarises the evaluation of the 1997 EURADOS questionnaire on dosimetric systems able to assess personal dose equivalent. In total, 56 approved dosimetric services in the European Union and Switzerland responded, together monitoring approximately 615,000 occupationally exposed persons. Of these services, 4...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.rpd.a006572

    authors: van Dijk JW,Bordy JM,Vanhavere F,Wernli C,Zamani-Valasiadou M

    更新日期:2001-01-01 00:00:00

  • LEAD COMPOSITE VS. NONLEAD PROTECTIVE GARMENTS: WHICH ARE BETTER? A MULTIVENDOR COMPARISON.

    abstract::This study aims to provide more insight in attenuation characteristics and corresponding lead (Pb) equivalences of a broad range of commercially available lead composite and nonlead protective garments. Thirty garments of five manufacturers (listed as 0.25-0.35-0.50 mm Pb equivalent) were tested. Transmission values w...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncw373

    authors: Peters SMB,Zweers D,de Lange F,Mourik JEM

    更新日期:2017-08-01 00:00:00

  • Evaluation of internal exposure of nuclear medicine staff through in vivo and in vitro bioassay techniques.

    abstract::The manipulation of a wide variety of unsealed sources in Nuclear Medicine results in a significant risk of internal exposure of the workers. 131I should be highlighted among the most frequently used radionuclides because of its large application for diagnosis and therapy of thyroid diseases. The increasing use of rad...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm365

    authors: Lucena EA,Rebelo AM,Araújo F,Sousa WO,Dantas AL,Dantas BM,Corbo R

    更新日期:2007-01-01 00:00:00