Abstract：
:Anaesthetic management in asthmatic patients has been focused on avoiding bronchoconstriction and inducing bronchodilation. However, the definition of asthma has changed over the past decade. Asthma has been defined as a clinical syndrome characterized by an inflammatory process that extends beyond the central airways to the distal airways and lung parenchyma. With this concept in mind, and knowing that asthma is a common disorder with increasing prevalence rates and severity worldwide, a rational choice of anaesthetic agents and procedures is mandatory. Thus, we pursued an update on the pharmacologic and technical anaesthetic approach for the asthmatic patient. When feasible, regional anaesthesia should be preferred because it reduces airway irritation and postoperative complications. If general anaesthesia is unavoidable, a laryngeal mask airway is safer than endotracheal intubation. Lidocaine inhalation, alone or combined with albuterol, minimizes histamine-induced bronchoconstriction. Propofol and ketamine inhibit bronchoconstriction, decreasing the risk of bronchospasm during anaesthesia induction. Propofol yields central airway dilation and is more reliable than etomidate or thiopental. Halothane, enflurane, and isoflurane are potent bronchodilators and can be helpful even in status asthmaticus. Sevoflurane has shown controversial results in asthmatic patients. Vecuronium, rocuronium, cisatracurium, and pancuronium do not induce bronchospasm, while atracurium and mivacurium can dose-dependently release histamine and should be cautiously administered in those patients. Further knowledge about the sites of action of anaesthetic agents in the lung, allied with our understanding of asthma pathophysiology, will establish the best anaesthetic approach for people with asthma.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Burburan SM,Xisto DG,Rocco PRsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
357-65issue
6eissn
0375-9393issn
1827-1596pii
R02064887journal_volume
73pub_type
杂志文章,评审abstract：:This article is a review of present knowledge of the hormonal and metabolic responses to trauma and surgery. The factors which may mediate the responses are discussed and the potential value of different therapeutic manipulations are reviewed. The accelerated breakdown of muscle following significant injury is the mos...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1992-06-01 00:00:00
abstract：:Fifteen to 30% of patients develop acute renal failure (ARF) following rhabdomyolysis and rhabdomyolysis accounts for 5 to 9% of all ARF. Experimental studies revealed two critical factors that predispose to myoglobinuric ARF: hypovolemia/dehydration and aciduria. At the nephron level, three basic mechanisms underlie ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：:Excessive adrenergic stimulation may be associated with several adverse events and contribute to increase mortality in critically ill septic patients. Few clinical data exist on the effects of adrenergic blockade in this setting. The objective of this study was to investigate the effect of a short acting b-blocker (es...
journal_title：Minerva anestesiologica
pub_type： 评论,杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：:Arrhythmias are common in hospitalized patients and during surgery. We present a case of positional atrial arrhythmia related to a peripherally inserted central catheter (PICC). There are other documented case reports of ventricular tachycardia precipitated by body position changes with a PICC. The immediate correctio...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：:The introduction of use of propofol in the anesthetists' pharmacopoeia has reinvigorated the research for a totally intravenous anaesthesia, for which the Authors propose a diagram. However, in experience related to the supplementary use of N2O, in virtue of its analgesic power, demonstrates yet another utility, permi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：BACKGROUND:To test validity, safety, costs and healing-outcome of surgical minitracheotomy after cannula removing. METHODS: DESIGN:Opened, perspective. Site: Polyvalent ICU. PATIENTS:40 patients underwent surgical minitracheotomy, in a year. Traditional surgical technique was adopted. Minitracheotomy was performed b...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：:Acute lung failure is associated with high mortality and usually requires mechanical ventilation to ensure adequate gas exchange. However, mechanical ventilation itself can be associated with major complications and can aggravate pre-existing lung disease, thus contributing to morbidity and mortality. Extracorporeal g...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:The aim of this paper was to determine if there were any significant differences between the effects of fentanyl delivered as a bolus or remifentanil delivered as a continuous infusion on the QT interval and QT dispersion (QTD) during the induction of anesthesia and tracheal intubation. METHODS:This was a p...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-02-01 00:00:00
abstract：:The Authors report a collapsial reaction during general anaesthesia for total hip replacement in a patient treated with tranylcipromine, an inhibitor of MAO, as antidepressant agent. She had discontinued drug intake eight days before. Nevertheless a serious collapsial reaction appeared in association with general anae...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:A qualified nursing care is mandatory in patients after SAH. Clinical and instrumental monitoring are basilar to assure the rapid control of dangerous ICP or CPP changes and of epileptic crisis. Prophylaxis of infections is greatly minimized when coherent treatments are applied to any invasive devices, patient body, p...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-01 00:00:00
abstract：:The selection of opioid drugs for anesthesia is often based on empirical judgment such as the selection of opioids with rapid elimination half-life for short surgical procedures (e.g. alfentanil), while opioids with longer elimination half-life (e.g. fentanyl, sufentanil) are used for longer procedures. A better insig...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：AIM:Microdialysis allows the biochemical analysis of interstitial fluids as a bedside procedure. This technique is of interest to evaluate the glucose dependent metabolism in hypoglycaemic patients. It was the aim to perform subcutaneous and blood microdialysis during hypoglycaemic clamp experiments in 12 healthy young...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:The authors illustrate some relevant emerging topics in pediatric anesthesia. Endotracheal cuffed tubes have entered into routine clinical practice in younger patients. Concerns about tracheal stenosis were overcome when manufactures began to produce a new class of high volume, low pressure endotracheal tubes. Ultraso...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the usefulness of the modified Harris-Benedict formula predicting Energy Expenditure (EE) in pressure support ventilated, critically ill patient. SETTING:The intensive care unit (ICU) of a teaching hospital. PATIENTS:Fiftyfive patients admitted to ICU for acute respiratory failure, requiring mec...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:Although the central nervous system is the primary endpoint of most general anesthetics, it is still the least monitored organ in clinical anesthesiology. In the last decade, technological research has expanded the application of near-infrared spectroscopy to allow continuous, non-invasive, and bedside monitoring of c...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Multiple organ dysfunction can occur in patients undergoing Veno-arterial Extra Corporal Membrane Oxygenation (VA-ECMO); however, liver function has not been well studied in this setting. METHODS:In a review of our institutional ECMO database (n=162), we collected aspartate (AST) and alanine (ALT) transamin...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.16.11442-7
更新日期：2017-03-01 00:00:00
abstract：:The overall use of allogeneic blood transfusions in clinical practice remains relatively high and still varies widely among centres and practitioners. Moreover, allogeneic blood transfusions have historically been linked with risks and complications: some of them (e.g. transfusion reactions and transmission of pathoge...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-01 00:00:00
abstract：:Modulation of inflammatory and immune response to critical illness has been the goal of much research in the last decade and a variety of drugs and nutrients (so called "immunonutrients") have been tested in experimental models with promising results. Though, in the clinical setting of intensive care, their efficacy h...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-01 00:00:00
abstract：INTRODUCTION:The world population is mostly male at birth, although there is a shift in predominance over 55 years of age with more females than males. Male gender was recently hypothesized to be a risk factor for sepsis and septic shock; the reasons and the consequences of this odd discrepancy are yet a matter of deba...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.17.12187-5
更新日期：2018-04-01 00:00:00
abstract：:Multimodal pain management, combining analgesics with different mode of action in order to minimize occurrence of side-effects still providing safe and efficacious pain management after ambulatory surgery has become standard of care. The combined use of local anaesthesia in order to reduce noxious influx during the pr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：:Factor VIIa might be a useful treatment for coagulopathy and massive hemorrhage following implantation of a mechanical circulatory assist device, but there is a theoretical risk of device thrombosis. To date this complication has not been reported. We describe the first case of clotting of a left ventricular assist de...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：:This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.17.12016-X
更新日期：2018-02-01 00:00:00
abstract：:A prolonged electrocardiographic QTc interval may be unsafe during general anesthesia; thus successful anesthetic management in patients affected by congenital long QT syndrome include avoidance of any event that increases sympathetic activity and drugs that prolong QT interval. Propofol seems to have less effect on t...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:Propanidid is a competitive inhibitor not only of serum cholinesterase, but of neuromuscular plaque and brain acetylcholinesterase also. The I50 of plaque acetylcholinesterase occurs at much higher concentrations of anaesthetic than for serum enzyme, this may depend on the environmental conditions under which propanid...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:A randomized, multicenter trial conducted in 32 northern European general intensive care units (ICUs) enrolled some patients with septic shock randomly assigned to receive a red blood cell transfusion when the hemoglobin (Hb) level was ≤7 g/dL ("lower threshold"; N.=502) or ≤9 g/dL ("higher threshold"; N.=496) through...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-09-01 00:00:00
abstract：AIM:The authors have evaluated remifentanil for intraoperative analgesia in endonasal endoscopic surgery for pituitary lesions. METHODS: EXPERIMENTAL DESIGN:a perspective, randomized and comparative study between remifentanil and fentanyl for intraoperative analgesia was performed in an operating room of the neurosur...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-03-01 00:00:00
abstract：BACKGROUND:Hypo- and hyperglycemia must be avoided to prevent additional brain damage following traumatic brain injury (TBI). However, the optimal blood glucose range requiring insulin remains unknown. Cerebral microdialysis is helpful in unmasking signs of metabolic impairment, thereby identifying deleterious blood gl...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：: ...
journal_title：Minerva anestesiologica
pub_type： 评论,信件
doi：10.23736/S0375-9393.19.13835-7
更新日期：2019-10-01 00:00:00
abstract：:The etiology, diagnosis, pathology and treatment of rhabdomyolysis due to intraoperative malpositioning and the medico-legal implications of physicians involved in the surgical treatment and anesthesia of the patient are described. According to the Italian law, the anesthesiologist is the only physician of the surgery...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:The bulbar hypotonizing activity of Althesin in eye surgery has been assessed. The anaesthetic was then utilized in the induction and maintenance of narcosis in cryoextraction operations on the crystalline lens. In the 50 narcoses examined, a mean decrease in ocular tone of 30% was noted with respect to basal value fi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
