Machine perfusion in liver transplantation: an essential treatment or just an expensive toy?

Abstract:

:This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to the immune response. Second, we report on improvement strategies of marginal liver grafts by different machine perfusion concepts and summarize perfusion approaches with recent clinical implementation.

journal_name

Minerva Anestesiol

journal_title

Minerva anestesiologica

authors

Schlegel AA,Kalisvaart M,Muiesan P

doi

10.23736/S0375-9393.17.12016-X

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

236-245

issue

2

eissn

0375-9393

issn

1827-1596

pii

S0375-9393.17.12016-X

journal_volume

84

pub_type

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