Abstract：
:This article is a review of present knowledge of the hormonal and metabolic responses to trauma and surgery. The factors which may mediate the responses are discussed and the potential value of different therapeutic manipulations are reviewed. The accelerated breakdown of muscle following significant injury is the most characteristic feature of the metabolic response. The magnitude of the muscle wasting that is potentially proportional to the extent of injury, leads to a marked cachexia which could be considered a part of the multiple organ failure. It does seem that the protein loss and the immunodepression which often occurs after major trauma may be important factors in determining morbidity and mortality of the patients. The prevention or the attenuation of the metabolic stress response could be beneficial in improving immunocompetence and minimizing complications after major trauma or surgery so that an earlier return to normal health could be achieved. At present there are few epidemiological data to support this view but it is an attractive concept in the management of a severely ill patients. We are aware that anaesthetic techniques, nutritional support, normothermia and hormonal manipulation can modify part of the hormonal and metabolic response to surgery. The knowledge of all of them and the clinical implications that their use could have, will be helpful to the anaesthesiologists and the Intensive Care physicians in their daily working in the operation theatre, intensive care unit or in the surgical ward.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Ronzoni G,Carli Fkeywords:
subject
Has Abstractpub_date
1992-06-01 00:00:00pages
323-46issue
6eissn
0375-9393issn
1827-1596journal_volume
58pub_type
杂志文章,评审abstract：:The bulbar hypotonizing activity of Althesin in eye surgery has been assessed. The anaesthetic was then utilized in the induction and maintenance of narcosis in cryoextraction operations on the crystalline lens. In the 50 narcoses examined, a mean decrease in ocular tone of 30% was noted with respect to basal value fi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：:The authors briefly discuss the advantages and limits of sedation in critically ill patients. They also focus the importance of an individualized sedative approach which provides pain relief and modulates stress response, allowing patients to be easily arousable and cooperative as necessary. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：:Extracorporeal membrane oxygenation (ECMO) can be used to preserve or enhance systemic oxygen delivery in patients with refractory cardiac or respiratory failure. Although widely accepted as a standard of care for many indications in children and for adult cardiogenic shock, ECMO for adult respiratory failure is more ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Thrombocytopenia is associated with worse outcomes in critically ill patients. The clinical relevance of other platelets indices is less studied. We investigated the ability of the platelets distribution width (PDW) and the mean platelet volume (MPV) to predict mortality in critically ill patients. We hypoth...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14528-0
更新日期：2020-09-22 00:00:00
abstract：AIM:To verify, in dissection adenotonsillectomy (AT) performed in Rose position under general anaesthesia with oro-tracheal intubation, the following: 1) the ability of tramadol to produce an effective intra- and postoperative analgesia without any considerable side effects or interferences with the normal post-surgica...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND:The Zero-Heat-Flux technology of the SpotOn® sensor to measure core temperature has been validated in vascular and cardiac surgery. Our aim was to assess its validity in gynecological surgery in terms of time of measurement, thermic status (hypo-, normo-, or hyperthermia) and the use of different warming dev...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.18.12188-2
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. In this work, we aimed to assess the feasibility of a new, non-invasive, mechatronic system for LOR detection in clinical settings. The s...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14031-8
更新日期：2020-07-01 00:00:00
abstract：:Anaesthesia in the case of subjects with multiple injuries is commonly a short-term emergency measure, in which a certain time is available for the implementation of intensive antishock therapy, or else anaesthesia for deferred emergency situations. Since the introduction of ketamine and althesin, the anaesthesiologic...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：:Ziconotide is a synthetic peptide equivalent of an w-conotoxin, obtained from the marine snail Conus magus, which acts by blocking N-type calcium channels in the spinal cord, reducing the perception of pain. It is a newly marketed drug, exclusively for intrathecal use, indicated for severe chronic pain. Ziconotide cam...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-12-01 00:00:00
abstract：:Although the central nervous system is the primary endpoint of most general anesthetics, it is still the least monitored organ in clinical anesthesiology. In the last decade, technological research has expanded the application of near-infrared spectroscopy to allow continuous, non-invasive, and bedside monitoring of c...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：AIM:High-flow-oxygen-therapy is provided by various techniques and patient interfaces, resulting in various inspired-fraction of oxygen (FiO2) and airway-pressure levels. However, tracheal measurements have never been performed. METHODS:Three oxygen-delivery-devices were evaluated: 1) standard-high-flow-oxygen-facemas...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the use of laryngeal mask airway (LMA)® Protector™ by comparison with traditional LMA for performing endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). METHODS:This was a retrospective observational single-center study including 143 patients w...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.19.13328-7
更新日期：2019-07-01 00:00:00
abstract：:This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.17.12016-X
更新日期：2018-02-01 00:00:00
abstract：AIM:The study compares the intraoperative effects of combined versus general anesthesia during major liver surgery. METHODS:In this prospective randomized study, 70 patients were divided into 2 group of 35 subjects. Group A received general anesthesia (thiopentone, fentanyl, vecuronium, sevoflurane in a closed circuit...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-12-01 00:00:00
abstract：AIM:Define pathophysiology, epidemiology, diagnosis and therapy in case of spinal bleeding after central neural blockade (CNB). METHODS:Spinal epidural hematoma (SEH) following CNB may occur due to vascular trauma from needle/catheter placement and can occur in subdural and epidural spaces. Epidural artery bleeding se...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2001-09-01 00:00:00
abstract：:The influence of diazepam, the hemisuccinic ester of oxazepam, fentanyl and pentazocine on pain-producing sensation after surgery was tested in 160 patients subjected to ordinary and major surgery. Use was made of Dundee and Moore's modification of Clutton-Brock's test, and Bromage's test. Analysis of the results indi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：BACKGROUND:Presurgical cognitive impairment (PreCI) is frequently seen in older age, but the influence on postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) remains unclear. The present study sought to determine the association between PreCI, POD and POCD with special focus to different PreCI d...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.13903-8
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Although blood gas analysis (BGA) is important for supplemental oxygen titration, it is invasive, intermittent, costly, and burdensome for staff. We assessed whether the Oxygen Reserve Index (ORi™), a novel pulse oximeter-based index that reflects the partial pressure of oxygen (PaO2), could determine the am...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14895-8
更新日期：2020-12-15 00:00:00
abstract：BACKGROUND:A new pulmonary artery catheter and monitor for continuous cardiac output measurement (CCO), based on thermodilution principle, has been recently developed. Aim of our study was to evaluate the new system by comparing data obtained with the CCO with the standard bolus thermodilution method (TD). METHODS:Nin...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:The surgical treatment of cervico-medullary traumas is indicated, in unstable lesions, in large lesions of the mobile rachidic segment in the presence of neurological complications or following worsening of prior neurological symptomatology. The purpose of the operation is at least three-fold: to obtain alignment of v...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：BACKGROUND:Acute normovolaemic anemia (ANA) frequently occurs during cardiopulmonary bypass (CPB) and major surgeries. We investigated whether fluids (with different compositions) used to replace blood elicit any degree of systemic or lung inflammatory response. METHODS:We evaluated systemic and pulmonary inflammatory...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2013-10-01 00:00:00
abstract：:It is well known that the organizational model of day surgery, concerning surgical problems defined by the literature as minor, has the aim of optimising the use of hospital resources and facilitating patients and their families, from a psychological and social point of view, by reducing hospitalisation time and the a...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:The Authors report on their experience about SvO2 continuous monitoring in order to find out the best therapeutic answer to inotropic drugs, knowing that, at constant values of SaO2 and Hb, possible variations of SvO2 reliably correspond with parallel variations of cardiac index (IC). Two groups of 15 patients each, s...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：BACKGRAUND:Pain is the primary reason for admission to the Emergency Department (ED). However, the management of pain in this setting is often inadequate because of opiophagia, fear of excessive sedation, and fear of compromising an adequate clinical assessment. METHODS:An intersociety consensus conference was held in...
journal_title：Minerva anestesiologica
pub_type： 指南,杂志文章,评审
doi：
更新日期：2015-02-01 00:00:00
abstract：:Early strategies to diagnose, manage and predict outcome of sepsis are essential to further improve morbidity and mortality of sepsis. Whereas biomarkers have become mainstay in other fields of medicine, their clinical utility in sepsis remains generally much less proven and so biomarkers are much less used clinically...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-01 00:00:00
abstract：:Critical ultrasound, apparently a recent field, is in fact the outcome of a slow process, initiated since 1946. The lung was traditionally not considered as part of ultrasound, yet we considered its inclusion as a priority in our definition of critical ultrasound. Acute respiratory failure is one of the most distressi...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-05-01 00:00:00
abstract：:Multimodal pain management, combining analgesics with different mode of action in order to minimize occurrence of side-effects still providing safe and efficacious pain management after ambulatory surgery has become standard of care. The combined use of local anaesthesia in order to reduce noxious influx during the pr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：AIM:The aim of this paper is to describe the anesthesiological management and the outcome of beating heart revascularization. METHODS:A prospective study has been performed in a tertiary teaching hospital on 100 consecutive patients undergoing off-pump coronary artery revascularization. The main features of anesthetic...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：AIM:Pain resulting from nerve lesions is classically referred to as a ''burning pain''. Both the axonal damage and sensitization of unmyelinated C-fibres have been considered as the possible generators of this sensation. The aim of this study was to verify the hypothesis that hot-burning sensations are produced by the ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Devices that limit microaspiration through the cuffs of endotracheal tubes could help prevent ventilator-associated pneumonia (VAP). The amount of tracheal microaspirations could be a relevant study endpoint. The aim of our study was to assess whether amylase measured in tracheal secretions constituted a rel...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
