Abstract:
:This study presents the results of further investigations on the antinociceptive profiles of an aqueous seed extract of Aframomum melegueta in rodents. The antinociceptive activity of the intraperitonal doses of 25-100 mg/kg of Aframomum melegueta was assessed using the formalin-induced paw licking, Randall-Selitto paw pressure and hot plate models of pain. The extract was found to produce a significant dose-dependent inhibition of the inflammatory but not the neurogenic pains associated with the formalin test. In the Randall-Sellito paw pressure test, the extract significantly reduced the nociceptive responses elicited by compression of inflamed hind paw of rats in a dose-related manner. However, Aframomum melegueta did not alter the pain threshold in non-inflamed paw and also failed to prolong the reaction time of the animals to noxious heat in the hot plate test. Taken together, these findings suggest that the aqueous seed extract of Aframomum melegueta possess peripheral analgesic activity.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Umukoro S,Ashorobi RBdoi
10.1016/j.jep.2006.08.025subject
Has Abstractpub_date
2007-02-12 00:00:00pages
501-4issue
3eissn
0378-8741issn
1872-7573pii
S0378-8741(06)00423-5journal_volume
109pub_type
杂志文章abstract::The study was conducted around Debre Libanos monastery from October 2005 to June 2006. A total of 250 villagers, 13 monks and 3 nuns were interviewed using semistructured questionnaire on the knowledge and use of medicinal plants. The informant consensus factor (ICF) and the fidelity level (FL) of the species were det...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2006.11.019
更新日期:2007-05-04 00:00:00
abstract::We studied the effect of Rosa davurica Pall. (Rosaceae) fruits (RdF) on immediate-type allergic reactions. RdF completely inhibited compound 48/80-induced systemic anaphylactic shock at the dose of 1 g/kg. When RdF was given as pretreatment, at concentrations ranging from 0.0001 to 1 g/kg, the serum histamine levels i...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(99)00013-6
更新日期:1999-10-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Precise target distribution is a key issue for further appreciate applications of fangjis (formulas) with similar efficacy and herbal constituents to maximize efficacy and minimize toxicity. AIM OF THE STUDY:To develop an algorithm for investigating the differential target distributions ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2021.113822
更新日期:2021-01-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Atherosclerosis has become a worldwide public health problem that seriously threatens human health. Leech is traditional Chinese medicine that can be utilized to treat cardiovascular disease. Based on the anti-atherosclerosis activity of leech hydrolysate, we separated and purified the le...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.112723
更新日期:2020-05-23 00:00:00
abstract::Viscum album L. herbs are used for the treatment of various diseases. Apart from their immunostimulatory, antitumor, and hypotension inducing activities, anti-inflammatory effects has also been recorded in the literature. Since the immunostimulatory activity of mistletoe is mainly attributed to a stimulation of the mo...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00038-5
更新日期:1998-07-01 00:00:00
abstract:AIM OF THE STUDY:Wei-Chang-An-Wan (WCAW), a traditional pharmaceutical preparation, has been used for treating various gastrointestinal (GI) diseases for several decades, but it is still poorly understood how it works on those disorders. This study was to investigate the effects of WCAW extract on GI tract. MATERIALS ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.07.027
更新日期:2009-09-25 00:00:00
abstract::Achyrocline satureioides (Lam.) DC. inflorescences have been used as remedies in folk medicine for the treatment of a variety of human ailments, particularly those of the gastrointestinal tract. Different extracts of inflorescences have been tested for anti-inflammatory, analgesic, antispasmodic, constipating and seda...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(88)90239-5
更新日期:1988-04-01 00:00:00
abstract::Methanol extracts of seven Malaysian medicinal plants were screened for antioxidant and nitric oxide inhibitory activities. Antioxidant activity was measured by using FTC, TBA and DPPH free radical scavenging methods and Griess assay was used for the measurement of nitric oxide inhibition in lipopolysaccharide (LPS) a...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2004.03.007
更新日期:2004-06-01 00:00:00
abstract::The hepatoprotective effects of rubiadin, a major constituent isolated from Rubia cordifolia Linn., were evaluated against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Rubiadin at a dose of 50, 100 and 200 mg/kg was administered orally once daily for 14 days. The substantially elevated serum enzymatic a...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.08.073
更新日期:2006-02-20 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lithospermi radix has been prescribed in traditional folk medicine to treat diverse diseases like cancer. AIM OF THE STUDY:The present study assessed the sub-chronic oral toxicity of an aqueous extract of lithospermi radix (WLR) in Fischer 344 rats over a period of 13 weeks. MATERIALS A...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.01.034
更新日期:2019-05-10 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:As a well-known traditional Chinese medicine the root bark of Aralia taibaiensis has traditionally been used as the medicine considered alleviating several disorders including diabetes mellitus (DM). Chikusetsu saponin IVa (CHS) has been defined as a major active ingredient of triterpenoi...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2015.02.032
更新日期:2015-04-22 00:00:00
abstract::The traditional utilization of plants as medicine in the Mediterranean region has been investigated. Field surveys were carried out among the people who live in the Taurus Mountains. Sixty-nine medicinal plants have been identified, which are listed with the vernacular names, the parts used, the methods of preparing t...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(93)90048-a
更新日期:1993-05-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Bullatine A, a C20-diterpenoid alkaloid and one of the major effective ingredients in Aconiti brachypodi Radix (Xue-shang-yi-zhi-hao), can block pain hypersensitivity in a variety of rodent models through expression of spinal microglial dynorphin A. AIM OF THE STUDY:To assess the interac...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.12.027
更新日期:2017-01-20 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Schinus lentiscifolius Marchand (syn. Schinus weinmannifolius Engl) is a plant native to Rio Grande do Sul (Southern Brazil) and has been used in Brazilian traditional medicine as antiseptic and antimicrobial for the treatment of many different health problems as well as to treat leucorrh...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.04.043
更新日期:2013-07-09 00:00:00
abstract:ETHNOPHARMACOLOGY RELEVANCE:Dendropanax morbifera Leveille (DM) has been used in traditional medicines for infectious and skin diseases, and dysmenorrhea. It exhibits a diverse therapeutic potential including anti-cancer, anti-thrombotic, anti-diabetic, anti-oxidant, and anti-inflammatory activities. AIM OF THE STUDY:...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.111874
更新日期:2019-06-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis has been employed extensively in many cultures since ancient times as antiseptic, wound healing, anti-pyretic and others due to its biological and pharmacological properties, such as immunomodulatory, antitumor, anti-inflammatory, antioxidant, antibacterial, antiviral, antifungal...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.112174
更新日期:2019-12-05 00:00:00
abstract::The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.11.037
更新日期:2008-03-05 00:00:00
abstract::Mangifera indica is commonly grown in many parts of the world. Its seeds have been used for anti-diarrhoeal activity in Indian traditional medicine. This study evaluates the potential anti-diarrhoeal activity of methanolic (MMI) and aqueous (AMI) extracts of seeds of M. indica in experimental diarrhoea, induced by cas...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(02)00250-7
更新日期:2003-01-01 00:00:00
abstract::The plant, Typhonium flagelliforme (Araceae), commonly known as the "rodent tuber" in Malaysia, is often used as an essential ingredient of herbal remedies for alternative cancer therapies. The hexane extract of this plant was evaluated for cytotoxic activity against in vitro culture on P388 murine leukaemia cells and...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(01)00274-4
更新日期:2001-09-01 00:00:00
abstract::Based on ethnopharmacological literature, 17 species of medicinal plants used in the traditional medicine in Papua New Guinea were collected. Extracts of different polarities were tested in a preliminary biological screening for their antimicrobial (Escherichia coli, Bacillus subtilis, Micrococcus luteus and Penicilli...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(95)01315-6
更新日期:1995-12-15 00:00:00
abstract:AIM OF THE STUDY:The performed investigations aimed on the identification of the anti-inflammatory principal of extracts of leaves of Sambucus ebulus L. (dwarf elder) in order to rationalize the traditional use of this plant for the treatment of chronically inflammatory diseases. MATERIALS AND METHODS:Dwarf elder leaf...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2010.10.049
更新日期:2011-01-27 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Uncaria tomentosa (Willd.) DC (Rubiaceae) is a species native to the Amazon rainforest and surrounding tropical areas that is endowed with immunomodulatory properties and widely used around the world. In this study we investigated the immunomodulatory potential of Uncaria tomentosa (UT) a...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.06.021
更新日期:2011-09-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Interleukin-8 (IL-8) as a pro-angiogenic factor is strongly associated with gastric cancer metastasis. Xiaotan Sanjie (XTSJ) decoction is an empirical compound prescription based on the phlegm theory of traditional Chinese medicine. Previous studies have shown that XTSJ decoction decrease...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.05.043
更新日期:2016-08-02 00:00:00
abstract:AIM OF THE STUDY:Huang-Lian-Jie-Du-Tang (HLJDT) is a traditional Chinese medicine with anti-inflammatory use. In the present study, the effects of its component herbs and pure components were observed on eicosanoid generation to find out the contributory components and their precise targets on arachidonic acid (AA) cas...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.03.055
更新日期:2011-05-17 00:00:00
abstract::The procedure for the preparation of Anna Pavala Sindhooram (APS), a drug based on the concepts of Indian medicine for the prevention and reversal of the atherosclerotic disease process is described in detail. The uniformity in the composition of samples of the drug obtained in 10 batches, prepared over a period of 5 ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(83)90001-6
更新日期:1983-05-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The genus Paeonia (Paeoniaceae), is one of the most important source of crude drugs in traditional Chinese medicine and investigation on many species is large. Up to now studies on Paeonia rockii, one of the eight species recognized in the section Moutan, are very limited. AIM OF THE STU...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.09.056
更新日期:2011-12-08 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Sambucus ebulus L. (S. ebulus) has had long-standing application in Traditional Persian Medicine for joint pain and for a variety of bone and joint disorders. According to traditional use of S. ebulus and its relevant pharmacologic properties, this study was designed to evaluate the effic...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2016.04.035
更新日期:2016-07-21 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Persian ethnomedicine several herbal remedies and functional foods have been used to treat migraine headache which are mostly summarized in Qarabadin-e-kabir (Aghili-Shirazi MH, 1773). One of them is Citron syrup (Sharbat-e-Balang) containing edible Citrus medica L. fruit juice and sug...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2015.12.040
更新日期:2016-02-17 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Korean red ginseng (KRG) has been shown to possess various biological activities including anti-inflammatory properties. AIM OF THE STUDY:We aimed to investigate the effects and mechanism of KRG on the prevention of atopic dermatitis (AD) using a mouse model. MATERIALS AND METHODS:The e...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.11.006
更新日期:2013-01-09 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Roots of Inula racemosa are used as a cardio protective in Ayurveda in India, being prescribed as a medicine for precordial chest pain, cough and dyspnoea, both singly and as a poly herbal. AIM:Evaluation of Phytoestrogenic activity of the root extracts of Inula racemosa and compounds is...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.09.001
更新日期:2018-01-10 00:00:00