Diesel exhaust exposure and bladder cancer risk.

Abstract:

:A total of 136 cases of men with urinary bladder cancer and 272 matched hospital controls were examined for potential exposure to diesel exhaust. A lifetime occupational history was obtained for all subjects in the study and assessment of exposure to diesel exhaust was based on the job titles of the subject and self-reported exposure. The risk was assessed by odds ratios, with adjustment for confounding variables, in particular cigarette smoking. There was no evidence of elevated risk in occupations with possible or probable exposure (the ORs adjusted for smoking were 1.1. and 0.9 respectively). Truck driving alone was also not associated with elevated risk (adjusted OR = 0.5). There was a weak positive crude association with any exposure, including self-reports (OR = 1.4); however after adjustment for smoking, the estimate did not retain statistical significance (OR = 1.2, 95% CI = 0.8-2.0). This study provides little to support the hypothesis of an excess of bladder cancer risk from occupational exposure to diesel exhaust.

journal_name

Eur J Epidemiol

authors

Iyer V,Harris RE,Wynder EL

doi

10.1007/BF00155549

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

49-54

issue

1

eissn

0393-2990

issn

1573-7284

journal_volume

6

pub_type

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