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Prevalence of and factors associated with glucosamine use in Canada.

Abstract：

OBJECTIVE:Glucosamine is commonly used for the treatment of osteoarthritis, and its use is increasing in the general population. The Canadian Multicentre Osteoporosis Study (CaMos) provided an opportunity to examine the prevalence of glucosamine use across age and gender groups, and to assess the factors associated with its use. METHOD:CaMos is a random, population-based sample of 9423 Canadians. Baseline assessments took place in 1996-1997 and the 5-year follow-up assessments in 2001-2002. The primary outcome of this analysis was glucosamine use at year 5. Prevalence estimates were age- and sex-standardized to the Canadian population. A number of factors potentially associated with glucosamine use were identified from the literature. Multivariable logistic regression was used to identify variables associated with glucosamine use. RESULTS:At 5 years, complete data were available for 7652 of the original 9423 participants (81.2%). For men, glucosamine use increased from 0.9% to 4.7% (weighted values), and for women, it increased from 1.3% to 8.2%. Glucosamine use was higher among older participants, those living in western Canada, and those with arthritis, back pain, higher calcium intake from supplements, physical activity and prior glucosamine use. CONCLUSIONS:Glucosamine use increased substantially over 5 years, and its use is associated with a number of factors. Some may use glucosamine to manage pain and symptoms of arthritis and back pain, while others use it as a preventive measure to maintain health.

journal_name

Osteoarthritis Cartilage

journal_title

Osteoarthritis and cartilage

authors

Hopman WM,Towheed TE,Gao Y,Berger C,Joseph L,Vik SA,Hanley DA,Carran J,Anastassiades T

doi

10.1016/j.joca.2006.06.003

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

1288-93

issue

12

eissn

1063-4584

issn

1522-9653

pii

S1063-4584(06)00182-8

journal_volume

14

pub_type

杂志文章,多中心研究

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