Simple sequence repeat-based comparative genomics between Brassica rapa and Arabidopsis thaliana: the genetic origin of clubroot resistance.

abstract：:The transcription factors WHITE COLLAR-1 (WC-1) and WHITE COLLAR-2 (WC-2) interact to form a heterodimeric complex (WCC) that is essential for most of the light-mediated processes in Neurospora crassa. WCC also plays a distinct non-light-related role as the transcriptional activator in the FREQUENCY (FRQ)/WCC feedback...

journal_title：Genetics

authors： Lee K,Dunlap JC,Loros JJ

更新日期：2003-01-01 00:00:00

abstract：:Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are also collected. Joint...

journal_title：Genetics

authors： Bilow M,Crespo F,Pan Z,Eskin E,Eyheramendy S

更新日期：2017-03-01 00:00:00

abstract：:Understanding which genes contribute to evolutionary change and the nature of the alterations in them are fundamental challenges in evolution. We analyzed regulatory and enzymatic genes in the maize anthocyanin pathway as related to the evolution of anthocyanin-pigmented kernels in maize from colorless kernels of its ...

journal_title：Genetics

authors： Hanson MA,Gaut BS,Stec AO,Fuerstenberg SI,Goodman MM,Coe EH,Doebley JF

更新日期：1996-07-01 00:00:00

abstract：:Clustering individuals to subpopulations based on genetic data has become commonplace in many genetic studies. Inference about population structure is most often done by applying model-based approaches, aided by visualization using distance-based approaches such as multidimensional scaling. While existing distance-bas...

journal_title：Genetics

authors： Greenbaum G,Templeton AR,Bar-David S

更新日期：2016-04-01 00:00:00

abstract：:In order to examine the operation of diversifying selection as the maintenance mechanism of excessive additive genetic variance for viability in southern populations in comparison with northern populations of Drosophila melanogaster, two sets of experiments were conducted using second chromosomes extracted from the Og...

journal_title：Genetics

authors： Takano T,Kusakabe S,Mukai T

更新日期：1987-10-01 00:00:00

abstract：:Hybrid male sterility (HMS) contributes to reproductive isolation commonly observed among house mouse (Mus musculus) subspecies, both in the wild and in laboratory crosses. Incompatibilities involving specific Prdm9 alleles and certain Chromosome (Chr) X genotypes are known determinants of fertility and HMS, and previ...

journal_title：Genetics

authors： Widmayer SJ,Handel MA,Aylor DL

更新日期：2020-10-01 00:00:00

abstract：:We analyzed linkage and chromosomal positions of genes in A. lyrata ssp. petraea that are located near the centromere (CEN) regions of A. thaliana, using at least two genes from the short and long arms of each chromosome. In our map, genes from all 10 A. thaliana chromosome arms are also tightly linked in A. lyrata. G...

journal_title：Genetics

authors： Kawabe A,Hansson B,Hagenblad J,Forrest A,Charlesworth D

更新日期：2006-07-01 00:00:00

abstract：:A number of fundamental processes comprise the cell division cycle, including spindle formation, chromosome segregation, and cytokinesis. Our current understanding of these processes has benefited from the isolation and analysis of mutants, with the meiotic divisions in the male germline of Drosophila being particular...

journal_title：Genetics

authors： Afshar K,Gönczy P,DiNardo S,Wasserman SA

更新日期：2001-03-01 00:00:00

abstract：:Neurospora crassa is an established reference organism to investigate carotene biosynthesis and light regulation. However, there is little evidence of its capacity to produce secondary metabolites. Here, we report the role of the fungal-specific regulatory velvet complexes in development and secondary metabolism (SM) ...

journal_title：Genetics

authors： Bayram ÖS,Dettmann A,Karahoda B,Moloney NM,Ormsby T,McGowan J,Cea-Sánchez S,Miralles-Durán A,Brancini GTP,Luque EM,Fitzpatrick DA,Cánovas D,Corrochano LM,Doyle S,Selker EU,Seiler S,Bayram Ö

更新日期：2019-07-01 00:00:00

abstract：:Receptor tyrosine kinases (RTKs) are an important family of signaling molecules with the unusual property that they are able to transduce their signals using the same downstream pathways. This has led to an unresolved debate as to whether individual receptors are interchangeable, or if each receptor can mediate specif...

journal_title：Genetics

authors： Leatherbarrow JR,Halfon MS

更新日期：2009-04-01 00:00:00

abstract：:A sample of 16 Minutes, representing 12 loci distributed over all the chromosome arms and including 3 pairs of alleles and 4 deficiencies, has been studied with respect to several developmental and recombinational parameters. Cell marker mutants located in most of the chromosome arms were used to assess (1) spontaneou...

journal_title：Genetics

authors： Ferrus A

更新日期：1975-04-01 00:00:00

abstract：:Precocious entry into S phase due to overproduction of G1 regulators can cause genomic instability. The mechanisms of this phenomenon are largely unknown. We explored the consequences of precocious S phase in yeast by overproducing a deregulated form of Swi4 (Swi4-t). Swi4 is a late G1-specific transcriptional activat...

journal_title：Genetics

authors： Sidorova JM,Breeden LL

更新日期：2002-01-01 00:00:00

abstract：:There are two distinct reasons for making comparisons of genetic variation for quantitative characters. The first is to compare evolvabilities, or ability to respond to selection, and the second is to make inferences about the forces that maintain genetic variability. Measures of variation that are standardized by the...

journal_title：Genetics

authors： Houle D

更新日期：1992-01-01 00:00:00

abstract：:Genetic studies of multidimensional phenotypes can potentially link genetic variation, gene expression, and physiological data to create multi-scale models of complex traits. The challenge of reducing these data to specific hypotheses has become increasingly acute with the advent of genome-scale data resources. Multi-...

journal_title：Genetics

authors： Tyler AL,Ji B,Gatti DM,Munger SC,Churchill GA,Svenson KL,Carter GW

更新日期：2017-06-01 00:00:00

abstract：:Natural selection leaves its footprints on protein-coding sequences by modulating their silent and replacement evolutionary rates. In highly expressed genes in invertebrates, these footprints are seen in the higher codon usage bias and lower synonymous divergence. In mammals, the highly expressed genes have a shorter ...

journal_title：Genetics

authors： Subramanian S,Kumar S

更新日期：2004-09-01 00:00:00

abstract：:Haploid Saccharomyces can change mating type through HO-endonuclease cleavage of an expressor locus, MAT, followed by gene conversion using one of two repository loci, HML or HMR, as donor. The mating type of a cell dictates which repository locus is used as donor, with a cells using HML and alpha cells using HMR. Thi...

journal_title：Genetics

authors： Houston P,Simon PJ,Broach JR

更新日期：2004-03-01 00:00:00

abstract：:Brassica self-incompatibility (SI) is controlled by SLG and SRK expressed in the stigma and by SP11/SCR expressed in the anther. We determined the sequences of the S domains of 36 SRK alleles, 13 SLG alleles, and 14 SP11 alleles from Brassica oleracea and B. rapa. We found three S haplotypes lacking SLG genes in B. ra...

journal_title：Genetics

authors： Sato K,Nishio T,Kimura R,Kusaba M,Suzuki T,Hatakeyama K,Ockendon DJ,Satta Y

更新日期：2002-10-01 00:00:00

abstract：:We study a situation that arises in the somatic evolution of cancer. Consider a finite population of replicating cells and a sequence of mutations: type 0 can mutate to type 1, which can mutate to type 2. There is no back mutation. We start with a homogeneous population of type 0. Mutants of type 1 emerge and either b...

journal_title：Genetics

authors： Iwasa Y,Michor F,Nowak MA

更新日期：2004-03-01 00:00:00

abstract：:Genetic analysis of 131 independent transpositions of the tetracycline-resistance element Tn10 from a single site in phage P22 into the histidine operon of Salmonella typhimurium reveals that Tn10 insertions are not randomly distributed along this chromosomal target. The insertions occur in 22 different "clusters"; in...

journal_title：Genetics

authors： Kleckner N,Steele DA,Reichardt K,Botstein D

更新日期：1979-08-01 00:00:00

abstract：:The type and frequency of simple sequence repeats (SSRs) in plant genomes was investigated using the expanding quantity of DNA sequence data deposited in public databases. In Arabidopsis, 306 genomic DNA sequences longer than 10 kb and 36,199 EST sequences were searched for all possible mono- to pentanucleotide repeat...

journal_title：Genetics

authors： Cardle L,Ramsay L,Milbourne D,Macaulay M,Marshall D,Waugh R

更新日期：2000-10-01 00:00:00

abstract：:Neurospora crassa has been a model organism for the study of circadian clocks for the past four decades. Among natural accessions of Neurospora crassa, there is significant variation in clock phenotypes. In an attempt to investigate natural allelic variants contributing to quantitative variation, we used a quantitativ...

journal_title：Genetics

authors： Kim TS,Logsdon BA,Park S,Mezey JG,Lee K

更新日期：2007-12-01 00:00:00

abstract：:USING A NEWLY DEVELOPED PLATING SYSTEM, WE HAVE MEASURED CELL SURVIVAL AND THE FREQUENCIES OF VARIATION IN AN INHERITED TRAIT AFTER TREATMENT OF SOYBEAN CELL SUSPENSIONS WITH DIFFERENT MUTAGENS: ethyl methanesulfonate (EMS), methyl methanesulfonate (MMS), N-Methyl-N'-nitro-N-nitroso-guanidine (MNNG), hycanthone (1-{[2...

journal_title：Genetics

authors： Weber G,Lark KG

更新日期：1980-09-01 00:00:00

abstract：:The homozygosity of a population will be influenced by any recent change in the population size. The "homozygosity test" of the neutral mutation hypothesis might also be influenced by a population change. A computer simulation method is described that establishes the significance levels of observed homozygosities afte...

journal_title：Genetics

authors： Watterson GA

更新日期：1986-04-01 00:00:00

abstract：:Phytochromes play an important role in light signaling and photoperiodic control of flowering time in plants. Here we propose that the red/far-red light photoreceptor HvPHYTOCHROME C (HvPHYC), carrying a mutation in a conserved region of the GAF domain, is a candidate underlying the early maturity 5 locus in barley (H...

journal_title：Genetics

authors： Pankin A,Campoli C,Dong X,Kilian B,Sharma R,Himmelbach A,Saini R,Davis SJ,Stein N,Schneeberger K,von Korff M

更新日期：2014-09-01 00:00:00

abstract：:The reproductive success of individual fire ant queens (Solenopsis invicta) previously has been shown to be strongly influenced by their genotype at a single enzyme-encoding gene, designated Pgm-3. This paper presents evidence that a second, tightly linked gene, designated Gp-9, is under similarly strong selection in ...

journal_title：Genetics

authors： Ross KG

更新日期：1997-04-01 00:00:00

abstract：:During meiosis homologous chromosomes replicate once, pair, experience recombination, and undergo two rounds of segregation to produce haploid meiotic products. The rec8(+), rec10(+), and rec11(+) genes of the fission yeast Schizosaccharomyces pombe exhibit similar specificities for meiotic recombination and rec8(+) i...

journal_title：Genetics

authors： Krawchuk MD,DeVeaux LC,Wahls WP

更新日期：1999-09-01 00:00:00

abstract：:The isozymic patterns of tyrosine aminotransferase, NADP malate dehydrogenase, NADP isocitrate dehydrogenase, and tetrazolium oxidase were examined by starch-gel electrophoresis in Tetrahymena pyriformis, syngen 1. The genetics of the alleles controlling these enzymes was studied through a breeding program. Each enzym...

journal_title：Genetics

authors： Borden D,Miller ET,Nanney DL,Whitt GS

更新日期：1973-08-01 00:00:00

abstract：:This article focuses on conducting global testing for association between a binary trait and a set of rare variants (RVs), although its application can be much broader to other types of traits, common variants (CVs), and gene set or pathway analysis. We show that many of the existing tests have deteriorating performan...

journal_title：Genetics

authors： Pan W,Kim J,Zhang Y,Shen X,Wei P

更新日期：2014-08-01 00:00:00

abstract：:The extent to which epistasis contributes to adaptation, population differentiation, and speciation is a long-standing and important problem in evolutionary genetics. Using recombinant inbred (RI) lines of Arabidopsis thaliana grown under natural field conditions, we have examined the genetic architecture of fitness-c...

journal_title：Genetics

authors： Malmberg RL,Held S,Waits A,Mauricio R

更新日期：2005-12-01 00:00:00

abstract：:Competition among domesticated plants or animals can have a dramatic negative impact on yield of a stand or farm. The usual quantitative genetic model ignores these competitive interactions and could result in seriously incorrect breeding decisions and acerbate animal well-being. A general solution to this problem is ...

journal_title：Genetics

authors： Muir WM

更新日期：2005-07-01 00:00:00