Anti-Müllerian hormone (AMH) in female reproduction: is measurement of circulating AMH a useful tool?

abstract：:We have studied the inositol phospholipid turnover response to thyrotrophin-releasing hormone (TRH) gonadotrophin-releasing hormone (GnRH) and arginine vasopressin (AVP) in five corticotroph and six somatotroph pituitary adenomas. GnRH (100 nM) increased inositol phospholipid turnover in five of five somatotroph adeno...

journal_title：Clinical endocrinology

authors： Levy A,Lightman SL,Hoyland J,Mason WT

更新日期：1990-07-01 00:00:00

abstract：:Exposure to maternal hypothyroxinemia during pregnancy, which is characterized by low free T4 but normal thyroid-stimulating hormone (TSH) levels, can negatively affect the foetus. This review provides an overview of present findings concerning the association between maternal hypothyroxinemia during pregnancy and chi...

journal_title：Clinical endocrinology

authors： Henrichs J,Ghassabian A,Peeters RP,Tiemeier H

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:We aimed to evaluate and contrast the hypothalamo-pituitary-adrenal (HPA) response to direct current (DC) cardioversion and electroconvulsive therapy (ECT). SUBJECTS:Six male subjects (mean age 61.2 years, range 46-74) with chronic atrial fibrillation were selected for cardioversion. Six subjects with depres...

journal_title：Clinical endocrinology

authors： Florkowski CM,Crozier IG,Nightingale S,Evans MJ,Ellis MJ,Joyce P,Donald RA

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:We have evaluated the efficacy of percutaneous ethanol injection as an alternative to surgery and iodine-131 treatment in solitary autonomous thyroid adenoma. DESIGN:Percutaneous ethanol injection (0.5-2.8 ml ethanol/ml nodular tissue) was performed under sonographic guidance in 3-5 (1-2 weekly) sessions; a ...

journal_title：Clinical endocrinology

authors： Monzani F,Goletti O,Caraccio N,Del Guerra P,Ferdeghini M,Pucci E,Baschieri L

更新日期：1992-05-01 00:00:00

abstract：:Delayed puberty is defined arbitrarily on the basis of statistical consideration, when no signs of puberty have occurred at 2.0 SD (13.4 years in girls and 13.8 in boys) above the mean chronological age for the onset of puberty. The vast majority of these patients have no endocrine abnormality and their pubertal devel...

journal_title：Clinical endocrinology

authors： Albanese A,Stanhope R

更新日期：1995-07-01 00:00:00

abstract：:Familial neurohypophysial diabetes insipidus (FNDI) is a rare autosomal dominant syndrome stemming from the absence of arginine vasopressin (AVP). More than thirty-five different germline mutations in the arginine vasopressin-neurophysin II gene have been reported. These mutations are either in the signal peptide or s...

journal_title：Clinical endocrinology

authors： Boson WL,Sarubi JC,d'Alva CB,Friedman E,Faria D,De Marco L,Wajchenberg B

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Patients with acromegaly demonstrate impaired quality of life (QoL), but data on long-term QoL changes in treated acromegaly are limited. This study evaluates and identifies factors that influence QoL in patients with long-term biochemical remission. DESIGN:The study consists of a cross-sectional arm compari...

journal_title：Clinical endocrinology

authors： Kyriakakis N,Lynch J,Gilbey SG,Webb SM,Murray RD

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of maternal hypothyroxinaemia during early gestation (fT4 below the lowest tenth percentile and TSH within the reference range: 0.15-2.0 mIU/l) on infant development, together with any subsequent changes in fT4 during gestation. DESIGN:A prospective 3-year follow-up study of pregnant w...

journal_title：Clinical endocrinology

authors： Pop VJ,Brouwers EP,Vader HL,Vulsma T,van Baar AL,de Vijlder JJ

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE AND DESIGN:The immediate early gene locus AP-1, incorporating the cellular oncogenes c-fos and c-jun (and their oncoprotein products Fos and Jun respectively) play a key role in regulating cell growth and differentiation. The myc-gene is also known to promote cell growth. In order to investigate the possible ...

journal_title：Clinical endocrinology

authors： Raghavan R,Harrison D,Ince PG,James RA,Daniels M,Birch P,Caldwell GI,Kendall-Taylor P

更新日期：1994-01-01 00:00:00

abstract：CONTEXT:Data on quantification and regulation of adipsin in human cerebrospinal fluid (CSF) are sparse, and the physiological role of adipsin as an adipokine crossing the blood-brain barrier (BBB) is uncertain. OBJECTIVES:This study quantified adipsin concentrations in paired serum and CSF samples of patients undergoi...

journal_title：Clinical endocrinology

authors： Schmid A,Hochberg A,Berghoff M,Schlegel J,Karrasch T,Kaps M,Schäffler A

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Foetal exposure to high testosterone concentrations seems to be involved in the development of mammalian brain and related to pervasive developmental disorders (PDDs). The aim of the current study was to test the hypothesis that children born from hyperandrogenic women with polycystic ovary syndrome (PCOS) ar...

journal_title：Clinical endocrinology

authors： Palomba S,Marotta R,Di Cello A,Russo T,Falbo A,Orio F,Tolino A,Zullo F,Esposito R,La Sala GB

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Adequate uterine growth is an essential component of pubertal induction with exogenous oestradiol in those with hypogonadism. Poor uterine development will render the individual vulnerable in the context of fertility. We assessed uterine size using ultrasound in those who had undergone pubertal induction trea...

journal_title：Clinical endocrinology

authors： Burt E,Davies MC,Yasmin E,Cameron-Pimblett A,Mavrelos D,Talaulikar V,Conway GS

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome. DESIGN:An evaluation of the standard clinical practice at one institution. PATIENTS:Ninety-one patients with Cushing's syndrome: 57 pituitary-dependent Cushing's disease, 10 adrenocortical adenomas, six adr...

journal_title：Clinical endocrinology

authors： Verhelst JA,Trainer PJ,Howlett TA,Perry L,Rees LH,Grossman AB,Wass JA,Besser GM

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:We recently identified a novel anorexigenic protein, nesfatin-1, which is processed from nesfatin/nucleobindin-2 (NUCB2). However, the clinical importance of this protein has not been determined. OBJECTIVE:To investigate its clinical significance in humans, we have established a new specific enzyme-linked i...

journal_title：Clinical endocrinology

authors： Tsuchiya T,Shimizu H,Yamada M,Osaki A,Oh-I S,Ariyama Y,Takahashi H,Okada S,Hashimoto K,Satoh T,Kojima M,Mori M

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Epidemiological studies on the cardiovascular risk of progestagen-only contraceptives are rare. With the present study we aimed to investigate the effect of the low-dose etonogestrel-releasing contraceptive implant Implanon on cardiovascular risk factors, including markers of inflammation. DESIGN:Longitudina...

journal_title：Clinical endocrinology

authors： Merki-Feld GS,Imthurn B,Seifert B

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:IGF-I has important actions on cell division, apoptosis, differentiation and metabolism, as well as on cell proliferation in vascular smooth muscle. Deficiency of GH, an important regulator of IGF-I, is associated with reduced well-being. IGF-I levels have been related to cognitive function in older individua...

journal_title：Clinical endocrinology

authors： Unden AL,Elofsson S,Knox S,Lewitt MS,Brismar K

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:Loss of E-cadherin is an important marker of epithelial tumour progression. The aims of this study were to explore whether E-cadherin expression and localization correlate to corticotroph tumour progression, relate the expression of the E-cadherin gene (CDH1) to immunohistochemical E-cadherin staining patter...

journal_title：Clinical endocrinology

authors： Evang JA,Berg JP,Casar-Borota O,Lekva T,Kringen MK,Ramm-Pettersen J,Bollerslev J

更新日期：2011-12-01 00:00:00

abstract：:Recent reports have shown that thyroid-stimulating immunoglobulins (TSI) may be detected by measuring cyclic AMP increases in cultures of isolated thyroid cells in response to added patient immunoglobulins (Ig). We have compared the frequency that TSI may be detected in the Ig fraction of 114 sera from 112 patients wi...

journal_title：Clinical endocrinology

authors： Grant SJ,Luttrell BM,Hales IB

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVE:To determine serum concentrations, intra-individual variability and impact of age-related co-morbidities on serum testosterone (T), dihydrotestosterone (DHT), estradiol (E(2)) and estrone (E(1)) in older men. DESIGN:Observational, repeated measures study. PARTICIPANTS:Men (n = 325) with 40 years and older s...

journal_title：Clinical endocrinology

authors： Sartorius G,Spasevska S,Idan A,Turner L,Forbes E,Zamojska A,Allan CA,Ly LP,Conway AJ,McLachlan RI,Handelsman DJ

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:Objective To evaluate the effect of strontium ranelate (SR) on bone turnover markers in women with established osteoporosis previously treated with teriparatide (TPTD--recombinant human PTH 1-34). DESIGN PATIENTS: Twenty-two postmenopausal Caucasian women (aged 65.7 +/- 1.7 years) with established osteoporos...

journal_title：Clinical endocrinology

authors： Anastasilakis AD,Goulis DG,Polyzos SA,Gerou S,Ballaouri I,Efstathiadou Z,Kita M,Avramidis A

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To compare the outcome of different treatment options used in several cases of non-islet cell tumour hypoglycaemia (NICTH). PATIENTS:Eight cases of NICTH were referred for diagnosis and monitoring following either surgical or medical treatment. METHODS:Serum samples collected throughout the time-course of e...

journal_title：Clinical endocrinology

authors： Teale JD,Wark G

更新日期：2004-04-01 00:00:00

abstract：:Serum thyroxine was consistently unmeasurable by radioimmunoassay in an elderly patient with myxoedema after successful treatment with oral thyroxine. Abnormal binding of thyroxine was suspected and shown to be due to the presence in serum of antibodies of the IgG variety. The characteristics of these antibodies with ...

journal_title：Clinical endocrinology

authors： Pearce CJ,Byfield PG,Edmonds CJ,Lalloz MR,Himsworth RL

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:Persistent elevation of urinary albumin excretion (UAE), even within normal range, is an independent predictor for cardiovascular disease. Accumulating research suggests that low levels of vitamin D and high levels of parathyroid hormone (PTH) also increase cardiovascular disease risk. This study is intended ...

journal_title：Clinical endocrinology

authors： Kim HW,Park H,Cho KH,Han K,Ko BJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The development of hepatocellular carcinoma in liver cirrhosis is associated with altered synthesis and secretion of several growth factors. AIM:The aim of this prospective study was to investigate the potential implication of IGF-I and its major binding protein (IGFBP-3) in the development of hepatocellula...

journal_title：Clinical endocrinology

authors： Mattera D,Capuano G,Colao A,Pivonello R,Manguso F,Puzziello A,D'Agostino L

更新日期：2003-12-01 00:00:00

abstract：:Changes in the excretion of urinary cyclic AMP, calcium and phosphate, and serum calcium, ionized calcium, and magnesium were studied after parathyroidectomy for primary hyperparathyroidism. Urinary cyclic AMP decreased rapidly and 8 of 11 patients had a significant reduction 1 h postoperatively, but changes in serum ...

journal_title：Clinical endocrinology

authors： Kohri K,Kataoka K,Yachiku S,Kurita T,Sonoda T

更新日期：1983-04-01 00:00:00

abstract：:The catechol oestrogen 2-hydroxyoestrone has been reported to lower serum prolactin concentrations acutely in normal women and it has been proposed that it may be effective in suppressing prolactin secretion in hyperprolactinaemic patients. Five women with hyperprolactinaemia and anovulation were studied. Following a ...

journal_title：Clinical endocrinology

authors： Franks S,Lightman SL,MaClusky NJ,Naftolin F,Lynch SS,Butt WR,Jacobs HS

更新日期：1981-10-01 00:00:00

abstract：:The uterine cross-sectional area (UXA) of women with polycystic (PCO) or multifollicular ovaries (MFO) is significantly larger and smaller, respectively, than those of normal women during the early-mid-follicular phase of the menstrual cycle. In the present study the distribution of oestradiol in plasma from normal wo...

journal_title：Clinical endocrinology

authors： Polson DW,Franks S,Reed MJ,Cheng RW,Adams J,James VH

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:The goal of our study was to determine the rate of neoplasms in patients with other pituitary adenomas (non-functioning and prolactinomas) in comparison with acromegaly which is known to favour the development of neoplasia. DESIGN AND PATIENTS:We reviewed clinical records for 220 patients with acromegaly, 15...

journal_title：Clinical endocrinology

authors： Popovic V,Damjanovic S,Micic D,Nesovic M,Djurovic M,Petakov M,Obradovic S,Zoric S,Simic M,Penezic Z,Marinkovic J

更新日期：1998-10-01 00:00:00

abstract：:We have previously reported that L-thyroxine treated patients may often have elevated serum T4 concentrations and yet show no clinical signs of hyperthyroidism. We found that such patients had normal serum T3 concentrations. The present study explored the relationship between serum T3 and T4 and dosage of L-thyroxine....

journal_title：Clinical endocrinology

authors： Rendell M,Salmon D

更新日期：1985-06-01 00:00:00

abstract：CONTEXT:Nonalcoholic fatty liver disease represents the hepatic manifestation of the metabolic syndrome. Nonalcoholic steatohepatitis (NASH) is the progressive form of liver injury. The pathophysiology that leads to NASH is not well understood. OBJECTIVE:We hypothesize that an altered cortisol metabolism in the liver ...

journal_title：Clinical endocrinology

authors： Konopelska S,Kienitz T,Hughes B,Pirlich M,Bauditz J,Lochs H,Strasburger CJ,Stewart PM,Quinkler M

更新日期：2009-04-01 00:00:00