Measurement of changes in antihypertensive drug utilisation following primary care educational interventions.

abstract：PURPOSE:We aimed to investigate the association between psychotropic treatment and risk of burn injury in individuals with mental illness. METHODS:A nested case-control study was conducted by using the National Health Insurance Research Database in Taiwan. A total of 3187 cases with burn injury under International Cla...

journal_title：Pharmacoepidemiology and drug safety

authors： Chang CM,Wu KY,Chiu YW,Wu HT,Tsai YT,Chau YL,Tsai HJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Our objectives were to determine performance of coded hyperkalemia diagnosis at identifying (1) clinically evident hyperkalemia and (2) serum potassium>6 mmol/L. METHODS:This retrospective observational study included 8722 patients with diabetes within an integrated healthcare system who newly initiated an ang...

journal_title：Pharmacoepidemiology and drug safety

authors： Raebel MA,Smith ML,Saylor G,Wright LA,Cheetham C,Blanchette CM,Xu S

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:Ejection fraction (EF) is crucial information when studying the use and effectiveness of therapies in patients with heart failure (HF) and myocardial infarction (MI). We aimed to assess the validity of claims data-based definitions of systolic dysfunction (SD). METHODS:We identified 1072 patients with EF recor...

journal_title：Pharmacoepidemiology and drug safety

authors： Li Q,Glynn RJ,Dreyer NA,Liu J,Mogun H,Setoguchi S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Laboratory technicians, laboratory supervisors, decontamination/remediation workers, and environmental investigators are at increased risk for repeated occupational exposure to Bacillus anthracis. In 2002, the Advisory Committee on Immunization Practices (ACIP) recommended pre-exposure vaccination for these ...

journal_title：Pharmacoepidemiology and drug safety

authors： Fowler GL,Baggs JM,Weintraub ES,Martin SW,McNeil MM,Gust DA

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:A recent regulatory warning and case reports have described the development of muscle complications with the use of 5-α reductase inhibitors (5ARIs). We wished to determine if there was a link between rhabdomyolysis and 5ARI usage. METHODS:We used a matched cohort design and linked administrative data from the...

journal_title：Pharmacoepidemiology and drug safety

authors： Welk B,McArthur E,Ordon M,Dirk J,Dixon S,Garg AX

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:High-grade cervical dysplasia or cervical intraepithelial neoplasia grade 2 or worse has been widely used as a surrogate endpoint in cervical cancer screening or prevention trials. METHODS:To identify high-grade cervical dysplasia and cervical cancer, we developed claims-based algorithms that incorporated a...

journal_title：Pharmacoepidemiology and drug safety

authors： Kim SC,Gillet VG,Feldman S,Lii H,Toh S,Brown JS,Katz JN,Solomon DH,Schneeweiss S

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Evidence is growing that early use of disease-modifying anti-rheumatic drugs (DMARDs) and combinations of these drugs provide optimal care for people with rheumatoid arthirits. The aim of this study was to describe objectively the pattern of consumption of DMARDs in the Australian community (community-based pre...

journal_title：Pharmacoepidemiology and drug safety

authors： Chan V,Tett SE

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:We present a new population-based pharmacoepidemiological (PE) database obtained from statutory health insurances (SHIs) that is able to generate signals, to monitor prescribed drugs and to describe drug utilisation. We discuss methodological features of the database and we assess to which degree this database ...

journal_title：Pharmacoepidemiology and drug safety

authors： Pigeot I,Ahrens W

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Estimating drug effectiveness and safety among older adults in population-based studies using administrative health care claims can be hampered by unmeasured confounding as a result of frailty. A claims-based algorithm that identifies patients likely to be dependent, a proxy for frailty, may improve confounding...

journal_title：Pharmacoepidemiology and drug safety

authors： Faurot KR,Jonsson Funk M,Pate V,Brookhart MA,Patrick A,Hanson LC,Castillo WC,Stürmer T

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate the concurrent validity of three European sets of drug-specific indicators of prescribing quality METHODS:In 200 hip fracture patients (≥65 years), consecutively recruited to a randomized controlled study in Sahlgrenska University Hospital in 2009, quality of drug treatment at study entry was asses...

journal_title：Pharmacoepidemiology and drug safety

authors： Wallerstedt SM,Belfrage B,Fastbom J

更新日期：2015-09-01 00:00:00

abstract：AIM:To determine the appropriate size of risk windows in both exposed and unexposed sub-cohorts. METHOD:Data was taken from a previous study of upper gastrointestinal haemorrhage and perforation. The length of each prescription for NSAIDs was estimated. The risk was calculated for the duration of a prescription plus i...

journal_title：Pharmacoepidemiology and drug safety

authors： McMahon AD,Evans JM,McGilchrist MM,McDevitt DG,MacDonald TM

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:In epidemiological studies, non-response may introduce bias and limit generalizability. In genetic pharmacoepidemiological research, collection of DNA might be a major reason for non-response. We determined reasons for non-response and compared characteristics of non-responders and responders in a pharmacogenet...

journal_title：Pharmacoepidemiology and drug safety

authors： van Wieren-de Wijer DB,Maitland-van der Zee AH,de Boer A,Kroon AA,de Leeuw PW,Schiffers P,Janssen RG,Psaty BM,van Duijn CM,Stricker BH,Klungel OH

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To study the human teratogenic potential of two acetylsalicylic acid (ASA) drugs ASA-100 mg and ASA-500 mg. DESIGN:Pair analysis of cases with congenital abnormalities and matched healthy controls. SETTINGS:The large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormali...

journal_title：Pharmacoepidemiology and drug safety

authors： Czeizel AE,Rockenbauer M,Mosonyi A

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND/AIM:The number of patients receiving amiodarone will increase in future years. As clinically significant hepatotoxicity associated with oral amiodarone is infrequent and difficult to predict, a new Bayesian-developed model is proposed to help in the causality assessment of amiodarone-induced liver injury. M...

journal_title：Pharmacoepidemiology and drug safety

authors： Llanos L,Moreu R,Peiró AM,Pascual S,Francés R,Such J,Horga JF,Pérez-Mateo M,Zapater P

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:In post-marketing drug safety surveillance, data mining can potentially detect rare but serious adverse events. Assessing an entire collection of drug-event pairs is traditionally performed on a predefined level of granularity. It is unknown a priori whether a drug causes a very specific or a set of related adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kulldorff M,Dashevsky I,Avery TR,Chan AK,Davis RL,Graham D,Platt R,Andrade SE,Boudreau D,Gunter MJ,Herrinton LJ,Pawloski PA,Raebel MA,Roblin D,Brown JS

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To study patterns of antiepileptic drugs (AED) prescribing, particularly valproate, during pregnancy over a 10-year period in the UK, Italy, and France. METHODS:Data on pregnancies conceived after 1 January 2007 with outcomes before 31 December 2016 were extracted from four European electronic health care data...

journal_title：Pharmacoepidemiology and drug safety

authors： Hurault-Delarue C,Morris JK,Charlton R,Gini R,Loane M,Pierini A,Puccini A,Neville A,Snowball J,Damase-Michel C,EUROmediSAFE consortium.

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Stimulants and atomoxetine should generally not be used or used only with caution in adults with pre-existing cardiovascular conditions. The extent to which pre-existing cardiovascular conditions influence initiation of these ADHD medications in adults is not known. METHODS:We performed a retrospective coho...

journal_title：Pharmacoepidemiology and drug safety

authors： Gerhard T,Winterstein AG,Olfson M,Huang C,Saidi A,Crystal S

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Recent evidence suggested that oral form of domperidone may possess pro-arrhythmic effects and increase the risk of ventricular arrhythmia. The concomitant use of cytochrome P450 (CYP) 3A4 isoenzyme inhibitors may further potentiate this association. Nevertheless, empirical data supporting these associations...

journal_title：Pharmacoepidemiology and drug safety

authors： Chen HL,Hsiao FY

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:Cancer-related fatigue (CRF) has been suggested to be associated with the occurrence of chemotherapy-induced nausea and vomiting (CINV). This study aims to evaluate the potential of CRF in predicting the occurrence of CINV. METHOD:This is a prospective, observational study. Recruited patients received mod...

journal_title：Pharmacoepidemiology and drug safety

authors： Poon KS,Un MK,Low XH,Cheung YT,Yap KY,Chan A

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Pharmacoepidemiologic studies of acute effects of episodic exposures often must control for many time-dependent confounders. Marginal structural models permit this and provide unbiased estimates when confounders are on the causal pathway. However, if causal pathway confounding is minimal, analyses with time-dep...

journal_title：Pharmacoepidemiology and drug safety

authors： Ray WA,Liu Q,Shepherd BE

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Breast cancer is the most common cancer in women worldwide. We attempted to investigate the association between the risk of breast cancer and use of captopril and other antihypertensive medication. METHODS:We performed a cohort study with a nested case-control analysis using the General Practitioner Research D...

journal_title：Pharmacoepidemiology and drug safety

authors： González-Pérez A,Ronquist G,García Rodríguez LA

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate the prevalence of first-generation antipsychotics (FGA) prescribed for treatment of psychiatric and neurological conditions and use of benztropine to reduce extrapyramidal side effects (EPS) by patient race/ethnicity in a nationally representative sample of adult outpatient...

journal_title：Pharmacoepidemiology and drug safety

authors： Cook TB,Reeves GM,Teufel J,Postolache TT

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:The Dietary Supplements Information Expert Committee (DSI-EC; the Committee) of the United States Pharmacopeial Convention (USP) reviews safety profiles of dietary supplements before development of USP-National Formulary (USP-NF) quality monographs. Because the veracity of dietary supplement adverse event repor...

journal_title：Pharmacoepidemiology and drug safety

authors： Gardiner P,Sarma DN,Low Dog T,Barrett ML,Chavez ML,Ko R,Mahady GB,Marles RJ,Pellicore LS,Giancaspro GI

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:To define periods of acceptable mortality reporting in primary care and to demonstrate through examples the implication for research using automated medical data. METHODS:Annual death counts were obtained for each primary care practice participating in The Health Improvement Network "THIN" (UK). Expected count...

journal_title：Pharmacoepidemiology and drug safety

authors： Maguire A,Blak BT,Thompson M

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Fear of discontinuing concomitant anti-epileptic drugs (AEDs) may lead to potentially unnecessary and perhaps unsafe polypharmacy. The effect of withdrawing concomitant AEDs on epilepsy control was therefore studied in long-term users of levetiracetam. METHODS:The EULEV cohort followed patients initiating leve...

journal_title：Pharmacoepidemiology and drug safety

authors： Droz-Perroteau C,Marchal C,Dureau-Pournin C,Lassalle R,Jové J,Robinson P,Lavernhe G,Vespignani H,Moore N,Fourrier-Réglat A,Eulev Study Group.

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To investigate the association between socioeconomic position and use of lipid-lowering drugs and ACE-inhibitors after an acute myocardial infarction (AMI) when simultaneously considering participation in the national quality register RIKS-HIA (Register of Information and Knowledge about Swedish Heart Intensive...

journal_title：Pharmacoepidemiology and drug safety

authors： Ohlsson H,Rosvall M,Hansen O,Chaix B,Merlo J

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:We sought to describe the epidemiology of viral respiratory-tract infections and patterns in prescriptions of cough and cold medications among young children who were suffering from viral respiratory tract infections (vRTIs). METHODS:We conducted a cross-sectional study to examine vRTI-episode occurrence and...

journal_title：Pharmacoepidemiology and drug safety

authors： Cheng CL,Kao Yang YH,Liu CC,Lee PI

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:UK primary care databases are frequently used in observational studies with cancer outcomes. We aimed to systematically review methods used by such studies to identify and validate incident cancers of the breast, colorectum, and prostate. METHODS:Medline and Embase (1980-2013) were searched for UK primary care...

journal_title：Pharmacoepidemiology and drug safety

authors： Rañopa M,Douglas I,van Staa T,Smeeth L,Klungel O,Reynolds R,Bhaskaran K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hydroxyzine is indicated for the management of anxiety, skin and sleep disorders. In 2015, the European Medicines Agency (EMA) concluded that hydroxyzine was pro-arrhythmogenic and changes to the product information were implemented in Europe. This study aimed to evaluate their impact in Denmark, Scotland, E...

journal_title：Pharmacoepidemiology and drug safety

authors： Morales DR,Macfarlane T,MacDonald TM,Hallas J,Ernst MT,Herings RMC,Smits E,Overbeek JA,Mitchell L,Morant S,Mackenzie I,Doney ASF,Robertson C,Bennie M,Wei L,Nicholson L,Morris C,Flynn RWF

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Current guidelines for the empiric treatment of uncomplicated urinary tract infection in women recommend that first-line trimethoprim-sulfamethoxazole (TMP-SMX) or ofloxacin be given for 3 days and nitrofurantoin for 5 days. Increasing the duration of treatment raises costs, and perhaps, the incidence of adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kahan NR,Chinitz DP,Kahan E

更新日期：2004-04-01 00:00:00