The state of dietary supplement adverse event reporting in the United States.

abstract：PURPOSE:We sought to determine the incidence and risks for severe thrombocytopenia (platelets < 50,000/μL) in United States Veteran patients treated with pegylated interferon (PEG-IFN) plus ribavirin for hepatitis C virus-positive (HCV) chronic liver disease (CLD). METHODS:Using a retrospective, observational cohort s...

journal_title：Pharmacoepidemiology and drug safety

authors： Hermos JA,Quach L,Gagnon DR,Weber HC,Altincatal A,Cho K,Lawler EV,Grotzinger KM

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:PCORnet, the National Patient-Centered Clinical Research Network, represents an innovative system for the conduct of observational and pragmatic studies. We describe the identification and validation of a retrospective cohort of patients with type 2 diabetes (T2DM) from four PCORnet sites. METHODS:We adapted e...

journal_title：Pharmacoepidemiology and drug safety

authors： Wiese AD,Roumie CL,Buse JB,Guzman H,Bradford R,Zalimeni E,Knoepp P,Morris HL,Donahoo WT,Fanous N,Epstein BF,Katalenich BL,Ayala SG,Cook MM,Worley KJ,Bachmann KN,Grijalva CG,Rothman RL,Chakkalakal RJ

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to generate data regarding the drug utilization pattern in pediatric population of our tertiary care hospital so that we could generate an essential medicine list (EML). BACKGROUND:Drug therapy accounts for a major portion of expenditure toward health care. Reduction in health ...

journal_title：Pharmacoepidemiology and drug safety

authors： Singh I,Mittal R,Shafiq N,Bharati B,Nigah RK,Pandhi P,Chaudhary RR,Malhotra S

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:Administration of pegylated interferon-alpha (IFN-alpha) and ribavirin in adults with chronic hepatitis C (CHC) is a recommended therapeutic standard. Nevertheless, this therapeutic regimen rises numerous controversies. The aim of this study was to analyze adverse effects during the treatment with pegylated IFN...

journal_title：Pharmacoepidemiology and drug safety

authors： Kowala-Piaskowska A,Mozer-Lisewska I,Figlerowicz M,Słuzewski W

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Our aim was to perform a systematic review of the methods currently being used to assess adherence and persistence in pharmacoepidemiological and pharmacoeconomic studies using automated databases. METHODS:A MEDLINE search of English language literature was performed to identify studies published between Janua...

journal_title：Pharmacoepidemiology and drug safety

authors： Andrade SE,Kahler KH,Frech F,Chan KA

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:Pharmacoepidemiologic studies of acute effects of episodic exposures often must control for many time-dependent confounders. Marginal structural models permit this and provide unbiased estimates when confounders are on the causal pathway. However, if causal pathway confounding is minimal, analyses with time-dep...

journal_title：Pharmacoepidemiology and drug safety

authors： Ray WA,Liu Q,Shepherd BE

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To examine and compare the quality of drug prescribing for older patients in nursing homes and home nursing services. METHODS:Cross-sectional study comprising 11,254 patients aged ≥ 65 years in nursing homes (n = 2986) and home nursing services (n = 8268). Potentially inappropriate medications were identified ...

journal_title：Pharmacoepidemiology and drug safety

authors： Halvorsen KH,Granas AG,Engeland A,Ruths S

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:This study describes the use of psychotropic drugs in a sample of eight Italian psychiatric hospitals. METHODS:A cross-sectional approach was used to collect information about sociodemographic and clinical characteristics of the inpatient population, and about medications prescribed. Prescribing behaviour in...

journal_title：Pharmacoepidemiology and drug safety

authors： Barbui C,D'Avanzo B,Frattura L,Saraceno B

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Antiepileptic drugs (AEDs) are also prescribed for therapeutic indications other than epilepsy (EPI), namely, psychiatric disorders (PSY). Our aim was to develop an algorithm able to distinguish between EPI and PSY among childbearing age women based on differences in AED exposure in these patient groups. ME...

journal_title：Pharmacoepidemiology and drug safety

authors： Naldi I,Piccinni C,Mostacci B,Renzini J,Accetta G,Bisulli F,Tappatà M,Piazza A,Pagano P,Bianchi S,D'Alessandro R,Tinuper P,Poluzzi E,ESPEA (Emilia-Romagna Study on Pregnancy and Exposure to Antiepileptic drugs) Group.

更新日期：2016-07-01 00:00:00

abstract：AIM:To study the influence of media attention about statins and ADRs on the level of disproportionality, expressed as the reporting odds ratio (ROR) for statins in the Lareb database, based on patients' reports. METHODS:Patient reports about statins, before and after the broadcast of a consumer programme about statins...

journal_title：Pharmacoepidemiology and drug safety

authors： van Hunsel F,van Puijenbroek E,de Jong-van den Berg L,van Grootheest K

更新日期：2010-01-01 00:00:00

abstract：:The following article from Pharmacoepidemiology and Drug Safety, “Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery” by F. Krummenauer, S. Kurz and H.B. Dick, published online on July 11 2006 inWiley Online Library (wileyonlinelibrary.com), has...

journal_title：Pharmacoepidemiology and drug safety

authors：

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To report the use of direct oral anticoagulants (DOACs) for stroke prevention in patients with atrial fibrillation in Scotland and advocate the standardisation of drug utilisation research methods. METHODS:Retrospective cohort study using linked administrative data. Patients included those with a diagnosis of ...

journal_title：Pharmacoepidemiology and drug safety

authors： Mueller T,Alvarez-Madrazo S,Robertson C,Bennie M

更新日期：2017-11-01 00:00:00

abstract：AIM:To determine the contribution of patients' adverse drug reaction (ADR) reports to signals detection, through a study of the signals sent by Lareb to the Dutch Medicines Evaluation Board. METHODS:The percentage of patient's ADR reports contributing to generate signals of adverse drug reactions was determined. A cas...

journal_title：Pharmacoepidemiology and drug safety

authors： van Hunsel F,Talsma A,van Puijenbroek E,de Jong-van den Berg L,van Grootheest K

更新日期：2011-03-01 00:00:00

abstract：:Schizophrenia is a life-threatening disease associated with mortality rates that are two to three times higher than those expected/observed in the general population. It is associated with high levels of suicide, particularly in young male patients soon after diagnosis. Delays in treating schizophrenia could contribut...

journal_title：Pharmacoepidemiology and drug safety

authors： Auquier P,Lançon C,Rouillon F,Lader M

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:In order to assess the short-term safety and tolerability of newly prescribed antihypertensive monotherapies in Korean patients, a prospective study was carried out. METHODS:A total of 1181 patients were observed from July 1997 to August 1999. At 2, 4, 8 and 12 weeks after initiation of antihypertensive monoth...

journal_title：Pharmacoepidemiology and drug safety

authors： Kim YS,Park HS,Sunwoo S,Byeon JJ,Song YM,Seo HG,Kim CH,Cheon KS,Yoo SM,Lee JK,Korea Post-Marketing Surveillance Research Group.

更新日期：2000-12-01 00:00:00

abstract：PURPOSE:To determine the risk factors and rate of medication administration error (MAE) alerts by analyzing large-scale medication administration data and related error logs automatically recorded in a closed-loop medication administration system using radio-frequency identification and barcodes. METHODS:The subject h...

journal_title：Pharmacoepidemiology and drug safety

authors： Hwang Y,Yoon D,Ahn EK,Hwang H,Park RW

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:In Spain, a human papillomavirus (HPV) vaccine was firstly marketed in 2006 and mainly administered in primary care (PC) practices for girls/women or schools. As for all vaccines, a valid data source is required for research on observational effectiveness or safety. The objective of this study is to identify an...

journal_title：Pharmacoepidemiology and drug safety

authors： Martín-Merino E,Llorente-García A,Montero-Corominas D,Huerta C

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:The objective of this study was to evaluate the level of use and therapy profile of antibacterial agents in hospitals. Further to explore whether type, size or geographical situation influenced antibacterial agents used. METHODS:Antibacterial use during 1998-1999, in 13 hospitals, including emergency, referral...

journal_title：Pharmacoepidemiology and drug safety

authors： Blix HS,Hartug S

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:Gut microbiota has been postulated to serve as a significant promoter of CRC formation, and colonic dysbiosis was previously reported in CRC tissue. Our aim was to evaluate the association between the type and cumulative duration of antibiotic exposure and CRC risk. METHODS:We conducted a nested case-control s...

journal_title：Pharmacoepidemiology and drug safety

authors： Boursi B,Haynes K,Mamtani R,Yang YX

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:Chronic kidney disease (CKD) is a prevalent and important outcome and covariate in pharmacoepidemiology. The Health Improvement Network (THIN) in the UK represents a unique resource for population-based studies of CKD. We compiled a valid list of Read codes to identify subjects with moderate to advanced CKD. M...

journal_title：Pharmacoepidemiology and drug safety

authors： Denburg MR,Haynes K,Shults J,Lewis JD,Leonard MB

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To develop and validate an algorithm to identify preterm infants in the absence of birth certificates within Medicaid data. METHODS:Medicaid fee-for-service claims data from Florida (FL) and Texas (TX) were linked to vital statistics data for infants who were continuously eligible during the first 3 months fol...

journal_title：Pharmacoepidemiology and drug safety

authors： Eworuke E,Hampp C,Saidi A,Winterstein AG

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Early detection of risky behaviors involving prescription opioids can assist prescribers in implementing safer prescribing. Patient-to-prescriber travel patterns may indicate potential opioid misuse. We introduce doctor hopping, patients bypassing nearby prescribers in favor of more distant ones, as a new spati...

journal_title：Pharmacoepidemiology and drug safety

authors： Young SG,Hayes CJ,Aram J,Tait MA

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Current guidelines for the empiric treatment of uncomplicated urinary tract infection in women recommend that first-line trimethoprim-sulfamethoxazole (TMP-SMX) or ofloxacin be given for 3 days and nitrofurantoin for 5 days. Increasing the duration of treatment raises costs, and perhaps, the incidence of adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kahan NR,Chinitz DP,Kahan E

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:The purpose of this study is to quantify the impact of the different outcomes and definitions of suicidality on the association between antiepileptic drugs (AEDs) and suicidality. METHODS:Retrospective cohort studies of selected AEDs (carbamazepine, gabapentin, lamotrigine, phenytoin, pregabalin, topiramate an...

journal_title：Pharmacoepidemiology and drug safety

authors： Schuerch M,Gasse C,Robinson NJ,Alvarez Y,Walls R,Mors O,Christensen J,Hesse U,de Groot M,Schlienger R,Reynolds R,Klungel O,de Vries F

更新日期：2016-03-01 00:00:00

abstract：:Benzodiazepines belong to the most widely prescribed group of drugs and are involved in a large proportion of the acute poisonings seen in emergency departments. The aim of the study was to examine whether a relationship exists between the number of poisonings with different types of benzodiazepines and the number of ...

journal_title：Pharmacoepidemiology and drug safety

authors： Verstraete AG,Buylaert WA,Blondeel L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Various strategies have been studied in the literature to address the significant underreporting of adverse drug reactions (ADRs) in healthcare systems worldwide. OBJECTIVES:We conducted a systematic review of the literature that assessed the impact of various strategies to improve ADR reporting published i...

journal_title：Pharmacoepidemiology and drug safety

authors： Li R,Zaidi STR,Chen T,Castelino R

更新日期：2020-01-01 00:00:00

abstract：:Meloxicam (Mobic((R))) was introduced in the UK in 1996 as a nonsteroidal anti-inflammatory drug (NSAID). To help evaluate the postmarketing experience with meloxicam in the UK, we used the General Practitioners Research Database (GPRD) to characterize the baseline risk of an upper gastrointestinal (GI) event among ne...

journal_title：Pharmacoepidemiology and drug safety

authors： Lanes SF,Rodrígeuz LA,Hwangg E

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:To conduct a synthesis of the literature on methods to evaluate the impacts of FDA regulatory actions and identify best practices for future evaluations. METHODS:We searched MEDLINE for manuscripts published between January 1948 and August 2011 that included terms related to FDA, regulatory actions, and empiri...

journal_title：Pharmacoepidemiology and drug safety

authors： Briesacher BA,Soumerai SB,Zhang F,Toh S,Andrade SE,Wagner JL,Shoaibi A,Gurwitz JH

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To assess the pattern of in-hospital changes in drug use in older patients from 2010 to 2016. METHODS:People aged 65 years or more acutely hospitalized in those internal medicine and geriatric wards that did continuously participate to the REgistro POliterapie Società Italiana di Medicina Interna register from...

journal_title：Pharmacoepidemiology and drug safety

authors： Franchi C,Ardoino I,Nobili A,Pasina L,Mannucci PM,Marengoni A,Perticone F,REPOSI investigators.

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Administrative claim databases are increasingly being used to study the safety of medication exposures during pregnancy. These studies are restricted to live births due to a reliance on algorithms for estimating gestational age that are based on codes associated with live delivery. Conditioning on live birth ma...

journal_title：Pharmacoepidemiology and drug safety

authors： Suarez EA,Landi SN,Conover MM,Jonsson Funk M

更新日期：2018-03-01 00:00:00