Abstract:
:The management of patients suspected of having ventilator-associated pneumonia (VAP) requires a strategy for diagnosis and treatment that is designated to: (1) identify patients with true lung bacterial infection; (2) determine the pathogen(s) responsible for pneumonia; (3) permit early selection of appropriate antimicrobial therapy; and (4) avoid indiscriminate administration of antibiotics. The use of bronchoscopic techniques to obtain bronchoalveolar lavage (BAL) specimens from the affected area in the lung allows definition of a strategy superior to that based exclusively on clinical evaluation. When BAL is performed before introduction of new antibiotics, it enables physicians to identify patients who need immediate treatment and help to select initial antibiotic therapy (with the results of direct examination of BAL liquid) and to withhold, deescalate, and/or optimize treatment (when the results of quantitative cultures are available), in a manner that is safe and well tolerated by patients. This strategy, based on clinical and bacteriological evaluation, prevents resorting to broad-spectrum drug coverage in all patients who develop signs and symptoms suggestive of pneumonia, thus minimizing the emergence of resistant flora, and redirects the search for another infection site.
journal_name
Semin Respir Crit Care Medjournal_title
Seminars in respiratory and critical care medicineauthors
Fagon JYdoi
10.1055/s-2006-933672keywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
34-44issue
1eissn
1069-3424issn
1098-9048journal_volume
27pub_type
杂志文章,评审abstract::In patients with acute intracerebral hemorrhage (ICH), one of the major concerns is ongoing bleeding or ICH expansion. Anticoagulated patients are at higher risk of ongoing expansion and worse outcome. It may be that rapid anticoagulation reversal can reduce the risk of expansion and improve clinical outcome. For thos...
journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章
doi:10.1055/s-2004-815601
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章
doi:10.1055/s-2003-39019
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章
doi:10.1055/s-0033-1358560
更新日期:2013-12-01 00:00:00
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pub_type: 历史文章,杂志文章,评审
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更新日期:2009-12-01 00:00:00
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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更新日期:2013-04-01 00:00:00
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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更新日期:2007-08-01 00:00:00
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章
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journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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abstract::The human Herpesviridae family consists of eight members: cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus 1 and 2 (HSV-1, -2), varicella-zoster virus (VZV), and human herpesvirus 6, 7, and 8 (HHV-6, -7, -8). Lifelong latency may develop in the host with reactivation during periods of relative imm...
journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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abstract::Pulmonary veno-occlusive disease (PVOD) is a rare disorder and can be misdiagnosed as idiopathic pulmonary arterial hypertension (iPAH). PVOD and iPAH often share a similar clinical presentation, genetic background, and hemodynamic profile. PVOD accounts for 5 to 10% of cases initially considered as iPAH. When compare...
journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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更新日期:2009-08-01 00:00:00
abstract::Pulmonary arterial hypertension (PAH) in the pediatric population is associated with a variety of underlying diseases and causes, significantly morbidity and mortality. In the majority of patients, PAH in children is idiopathic or associated with congenital heart disease (CHD), with pulmonary hypertension (PH) associa...
journal_title:Seminars in respiratory and critical care medicine
pub_type: 杂志文章,评审
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更新日期:2013-10-01 00:00:00