Spatial organization of cofilin in dendritic spines.

abstract：:Long-term treatment with diazepam, a full allosteric modulator of the GABA(A) receptor, results in tolerance to its anticonvulsant effects, whereas an equipotent treatment with the partial allosteric modulator imidazenil does not produce tolerance. Use of subunit-specific antibodies linked to gold particles allowed an...

journal_title：Neuroscience

authors： Pesold C,Caruncho HJ,Impagnatiello F,Berg MJ,Fritschy JM,Guidotti A,Costa E

更新日期：1997-07-01 00:00:00

abstract：:The prolonged maintenance of hippocampal long-term potentiation (LTP) seems to require heterosynaptic events during its induction. We have previously shown that stimulation of the basolateral nucleus of the amygdala (BLA) within a distinct time window can reinforce a transient early-LTP into a long-lasting late-LTP in...

journal_title：Neuroscience

authors： Frey S,Bergado JA,Frey JU

更新日期：2003-01-01 00:00:00

abstract：:Mice provide a highly valuable resource for investigating learning and memory processes; however, many of the established tasks for evaluating learning and memory were developed for rats. Behaviors of mice in these tasks appear to be driven by different motivational factors, and as a result, they often do not perform ...

journal_title：Neuroscience

authors： Pistell PJ,Ingram DK

更新日期：2010-03-10 00:00:00

abstract：:Carbachol, a long-acting cholinergic agonist, was microinjected (4 micrograms/250 nl per 90 s) into 90 sites within the anterodorsal pontine tegmentum of four cats and the time to onset and percentage of time spent in a desynchronized sleep-like state during 40 min postinjection were calculated. Compared with more pos...

journal_title：Neuroscience

authors： Yamamoto K,Mamelak AN,Quattrochi JJ,Hobson JA

更新日期：1990-01-01 00:00:00

abstract：:Most functional imaging studies of memory retrieval investigate memory for standardized laboratory stimuli. However, naturally acquired autobiographical memories differ from memories of standardized stimuli in important ways. Neuroimaging studies of natural memories may reveal distinctive patterns of brain activation ...

journal_title：Neuroscience

authors： Maddock RJ,Garrett AS,Buonocore MH

更新日期：2001-01-01 00:00:00

abstract：:The distribution of different metabotropic glutamate receptors (mGluRs 1a, 1b, 1c, 2/3, 4 and 5) has been compared in the superior colliculus of the rat, cat and ferret using immunohistochemical techniques and light microscopy. We found that although there are differences in labelling patterns between the species, the...

journal_title：Neuroscience

authors： Cirone J,Sharp C,Jeffery G,Salt TE

更新日期：2002-01-01 00:00:00

abstract：:Neuroinflammatory processes associated with induction of cyclooxygenase (COX) have been implicated in the deleterious events resulting in neurodegeneration. The present study was designed to investigate the impact of acute methamphetamine (MA) administration on COX expression and prostaglandin E2 (PGE(2)) production, ...

journal_title：Neuroscience

authors： Zhang X,Dong F,Mayer GE,Bruch DC,Ren J,Culver B

更新日期：2007-12-19 00:00:00

abstract：:Incubation of PC12 cells with S-100 protein induces a rapid (0.5-1.0 min) rise of intracellular Ca2+ which lasts for the whole period of incubation. This effect is abolished in a Ca(2+)-free medium or in the presence of 1.0 microM Ni2+, an inhibitor of calcium channels. The rise in intracellular Ca2+ is followed by a ...

journal_title：Neuroscience

authors： Mariggió MA,Fulle S,Calissano P,Nicoletti I,Fanó G

更新日期：1994-05-01 00:00:00

abstract：:Stem cells have a number of properties, which make them excellent candidates for the treatment of various neurologic disorders, the most important of which being their ability to migrate to and differentiate predictably at sites of pathology in the brain. The disease-directed migration and well-characterized different...

journal_title：Neuroscience

authors： Carney BJ,Shah K

更新日期：2011-12-01 00:00:00

abstract：:Our human visual system exploits spatiotemporal regularity to interpret incoming visual signals. With a dynamic stimulus sequence of four collinear bars (predictors) appearing consecutively toward the fovea, followed by a target bar with varying contrasts, we have previously found that this predictable spatiotemporal ...

journal_title：Neuroscience

authors： Roebuck H,Bourke P,Guo K

更新日期：2014-03-28 00:00:00

abstract：:We investigated functional organization of the vagus nerve (N. X)- and glossopharyngeal nerve (N. IX)-related nuclei in the embryonic rat brainstem and compared their development and spatial distribution patterns, using multiple-site optical recording with a fast voltage-sensitive dye, NK2761. Intact brainstem prepara...

journal_title：Neuroscience

authors： Momose-Sato Y,Nakamori T,Sato K

更新日期：2011-09-29 00:00:00

abstract：:Central blockade of mineralocorticoid receptors (MRs) or angiotensin II type 1 receptors (AT1Rs) attenuates aldosterone (aldo)-salt induced hypertension. We examined the role of the subfornical organ (SFO), aldo synthesized locally in the brain, and MR and AT1R specifically in the paraventricular nucleus (PVN) in aldo...

journal_title：Neuroscience

authors： Wang HW,Huang BS,Chen A,Ahmad M,White RA,Leenen FH

更新日期：2016-02-09 00:00:00

abstract：:Changes in cellular activity in the subthalamic nucleus are a cardinal feature of Parkinson's disease and occur in rodents after lesions of the nigrostriatal pathway, a model of Parkinson's disease. GABA-ergic neurons from the globus pallidus provide a major input to the subthalamic nucleus. Previous electrophysiologi...

journal_title：Neuroscience

authors： Mehta A,Menalled L,Chesselet MF

更新日期：2005-01-01 00:00:00

abstract：:In the present study the effect of cocaine on thymidine, uridine and leucine incorporation was assessed in primary cortical glial and C6 glioma cells. Cocaine exposure for 24 h inhibited thymidine and uridine incorporation in cortical glial and C6 glioma cells. However, the effect of cocaine on uridine incorporation w...

journal_title：Neuroscience

authors： Garg UC,Turndorf H,Bansinath M

更新日期：1993-11-01 00:00:00

abstract：:Before movement onset, during the reaction time, excitability of M1 is selectively modulated by somatosensory inputs, only in the movement-related muscle. If a similar mechanism operates before the onset of mental movements, then somatosensory afferent inputs are exploited during cognitive representation of movement. ...

journal_title：Neuroscience

authors： Bonassi G,Bisio A,Lagravinese G,Ruggeri P,Bove M,Avanzino L

更新日期：2019-06-15 00:00:00

abstract：:Two major systems of cholinergic projection neurons are found within the centrum of the mammalian brain: the basal nuclear complex, projecting predominantly to the cerebral cortex, amygdala, and hippocampus, and the pontomesencephalotegmental network, innervating primarily the thalamus. Neurons comprising the latter n...

journal_title：Neuroscience

authors： Consolo S,Bertorelli R,Forloni GL,Butcher LL

更新日期：1990-01-01 00:00:00

abstract：:Arc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. In the present study, the possibility that Arc would be specifically upregulated in rats during the acquisition of a quickly...

journal_title：Neuroscience

authors： Kelly MP,Deadwyler SA

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:GABA is an important inhibitory transmitter in the CNS. In the enteric nervous system, however, both excitatory and inhibitory actions have been reported. Here, we investigated the effects of GABA on the intracellular Ca2+ concentration of guinea-pig myenteric neurons (at 35 degrees C) using Fura-2-AM. Neuro...

journal_title：Neuroscience

authors： Reis HJ,Vanden Berghe P,Romano-Silva MA,Smith TK

更新日期：2006-05-12 00:00:00

abstract：:Nerve injury often leads to chronic, sometimes excruciating, pain. The mechanisms contributing to this syndrome include neurochemical plasticity in neurons involved in the earliest stages of pain transmission. Endomorphin-2 (Tyr-Pro-Phe-Phe-NH(2)) is an endogenous morphine-like substance that binds to the mu-opioid re...

journal_title：Neuroscience

authors： Smith RR,Martin-Schild S,Kastin AJ,Zadina JE

更新日期：2001-01-01 00:00:00

abstract：:Executive control requires behavioral adaptation to environmental contingencies. In the stop signal task (SST), participants exhibit slower go trial reaction time (RT) following a stop trial, whether or not they successfully interrupt the motor response. In previous fMRI studies, we demonstrated activation of the righ...

journal_title：Neuroscience

authors： Zhang Y,Ide JS,Zhang S,Hu S,Valchev NS,Tang X,Li CR

更新日期：2017-08-15 00:00:00

abstract：:The function of N-methyl-d-aspartate (NMDA) receptors in primary afferents remains controversial, in particular regarding their ability to evoke substance P release in the spinal cord. The objective of this study was, first, to confirm that substance P release evoked by NMDA is mediated by NMDA receptors in primary af...

journal_title：Neuroscience

authors： Chen W,Zhang G,Marvizón JC

更新日期：2010-03-31 00:00:00

abstract：:Brain injury-derived neurotrophic peptide is a 13-amino acid peptide derived from a 15,000 mol. wt neurotrophic factor released from sites of mechanical injury in neonatal rat brain. This peptide promotes survival of septal cholinergic neurons and mesencephalic dopaminergic neurons, and protects hippocampal neurons fr...

journal_title：Neuroscience

authors： Hama T,Maruyama M

更新日期：2000-01-01 00:00:00

abstract：:Diabetes type 1 is a common autoimmune disease manifesting by insulin deficiency and hyperglycemia, which can lead to dementia-like brain dysfunctions. The factors triggering the pathological processes in hyperglycemic brain remain unknown. We reported in this study that brain areas with different susceptibility to di...

journal_title：Neuroscience

authors： Fiedorowicz A,Prokopiuk S,Zendzian-Piotrowska M,Chabowski A,Car H

更新日期：2014-01-03 00:00:00

abstract：:The startle reflex is evoked by strong acoustic or tactile stimuli, or by electrical stimulation of acoustic or tactile pathways. To dissociate the contributions of acoustic and tactile pathways, stimulating electrodes were placed in adjacent cochlear and trigeminal nuclei. The currents needed to evoke startle-like re...

journal_title：Neuroscience

authors： Scott BW,Frankland PW,Li L,Yeomans JS

更新日期：1999-01-01 00:00:00

abstract：:The diffusible second messenger, nitric oxide, is synthesised in central neurons in response to activation of glutamate receptors or other stimuli that increase cytosolic Ca2+ concentrations. Among the many roles suggested for nitric oxide in the central nervous system is that of mediating synaptic plasticity. For exa...

journal_title：Neuroscience

authors： Boulton CL,Southam E,Garthwaite J

更新日期：1995-12-01 00:00:00

abstract：:A better understanding of BOLD responses stems from a better characterization of the brain's ability to metabolize glucose and oxygen. Non-invasive techniques such as functional magnetic resonance spectroscopy (fMRS) have thus been developed allowing for the reproducible assessment of metabolic changes during barrel c...

journal_title：Neuroscience

authors： Sonnay S,Duarte JMN,Just N

更新日期：2017-03-27 00:00:00

abstract：:Latent inhibition, the process whereby pre-exposure to a conditioned stimulus without consequence impairs subsequent learning of an association between the conditioned stimulus and an unconditioned stimulus, is reportedly disrupted in both amphetamine-treated rats and in acute schizophrenics. This has led to the sugge...

journal_title：Neuroscience

authors： Murphy CA,Pezze M,Feldon J,Heidbreder C

更新日期：2000-01-01 00:00:00

abstract：:Growing evidence suggests that non-N-methyl-D-aspartate receptor activation may contribute to neuronal death in both acute and chronic neurological diseases. The intracellular processes that mediate this form of neuronal death are poorly understood. We have previously characterized a model of kainic acid neurotoxicity...

journal_title：Neuroscience

authors： Simonian NA,Getz RL,Leveque JC,Konradi C,Coyle JT

更新日期：1996-12-01 00:00:00

abstract：:Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived. Recent evidence supports the hypothesis that tinnitus is related to neuronal hyperactivity in auditory brain regions, and consequently drugs that increase GABAergic neurotransmission in the CNS, such as the GABA(B) receptor a...

journal_title：Neuroscience

authors： Zheng Y,McPherson K,Smith PF

更新日期：2014-01-31 00:00:00

abstract：:The forced swim test (FST) has been considered as a pharmacologically valid test of the depressive syndrome in rodents. However, few studies have focused on neurochemical and behavioral responses during FST in both male and female rats. Thus, we investigated certain behavioral and neuroendocrine responses as well as t...

journal_title：Neuroscience

authors： Drossopoulou G,Antoniou K,Kitraki E,Papathanasiou G,Papalexi E,Dalla C,Papadopoulou-Daifoti Z

更新日期：2004-01-01 00:00:00