Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization.

abstract：:Mouse fibroblasts (L cells) were infected in suspension with Chlamydia psittaci (6BC) and then plated out on a solid substrate at a density of 80 cells per cm2 so that the effect of chlamydial infection on the division of single host cells and their progeny could be determined. Uninfected L cells multiplied with a mea...

journal_title：Infection and immunity

authors： Horoschak KD,Moulder JW

更新日期：1978-01-01 00:00:00

abstract：:Studies conducted with F1 and F2 progeny of crosses between strains of inbred mice that differ greatly in their capacity to make an antibody response to type III pneumococcal polysaccharide, dextran B-1355, and lipopolysaccharide from Escherichia coli 0113 have shown that multiple genes influence the magnitude of the ...

journal_title：Infection and immunity

authors： Baker PJ,Rudbach JA,Prescott B,Caldes G,Evans C,Stashak PW

更新日期：1984-07-01 00:00:00

abstract：:Toll-like receptors (TLRs) play a critical role in early immune recognition of Aspergillus, which can regulate host defense during invasive pulmonary Aspergillosis (IPA). However, the role of TLR7 in the pathogenesis of IPA remains unknown. In this study, an in vivo model of IPA was established to investigate the cont...

journal_title：Infection and immunity

authors： Xu B,Luo Q,Gong Y,Li J,Cao J

更新日期：2021-01-25 00:00:00

abstract：:The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to translocate a set of effector proteins into the host cell, which mod...

journal_title：Infection and immunity

authors： Hansen-Wester I,Chakravortty D,Hensel M

更新日期：2004-05-01 00:00:00

abstract：:A toxin associated with Toxoplasma gondii infection was obtained from the trophozoites and culture medium used to propagate the parasite in cell cultures. The toxin, named Toxofactor (TF), administered parenterally or nonparenterally in adult mice, produces transient symptoms of lethargy, ruffled fur, and body weight ...

journal_title：Infection and immunity

authors： Grimwood B,O'Connor G,Gaafar HA

更新日期：1983-12-01 00:00:00

abstract：:Escherichia coli is a major cause of enteric/diarrheal diseases, urinary tract infections, and sepsis. E. coli K1 is the leading gram-negative organism causing neonatal meningitis, but the microbial basis of E. coli K1 meningitis is incompletely understood. Here we employed comparative genomic hybridization to investi...

journal_title：Infection and immunity

authors： Yao Y,Xie Y,Kim KS

更新日期：2006-04-01 00:00:00

abstract：:An immunomodulatory role of arthropod saliva has been well documented, but evidence for an effect on Plasmodium sp. infectiousness remains controversial. Mosquito saliva may orient the immune response toward a Th2 profile, thereby priming a Th2 response against subsequent antigens, including Plasmodium. Orientation to...

journal_title：Infection and immunity

authors： Lawaly R,Konate L,Marrama L,Dia I,Diallo D,Diène Sarr F,Schneider BS,Casademont I,Diallo M,Brey PT,Sakuntabhai A,Mecheri S,Paul R

更新日期：2012-06-01 00:00:00

abstract：:The rfb region from Vibrio cholerae O139 strain MO45 was cloned from cosmid gene banks established in Escherichia coli HB101, using an immunoblot assay for screening of the correct clones. Immunoblot analysis of lipopolysaccharide (LPS) preparations revealed the presence of two types of positive clones: (i) those expr...

journal_title：Infection and immunity

authors： Favre D,Cryz SJ Jr,Viret JF

更新日期：1996-09-01 00:00:00

abstract：:Complement is a critical component of antimicrobial immunity. Various complement regulatory proteins prevent host cells from being attacked. Many pathogens have acquired the ability to sequester complement regulators from host plasma to evade complement attack. We describe here how Streptococcus pneumoniae adopts a st...

journal_title：Infection and immunity

authors： Haleem KS,Ali YM,Yesilkaya H,Kohler T,Hammerschmidt S,Andrew PW,Schwaeble WJ,Lynch NJ

更新日期：2018-12-19 00:00:00

abstract：:MtsABC is a Streptococcus pyogenes ABC transporter which was previously shown to be involved in iron and zinc accumulation. In this study, we showed that an mtsABC mutant has impaired growth, particularly in a metal-depleted medium and an aerobic environment. In metal-depleted medium, growth was restored by the additi...

journal_title：Infection and immunity

authors： Janulczyk R,Ricci S,Björck L

更新日期：2003-05-01 00:00:00

abstract：:We have shown that a member of the 70-kDa heat shock protein (Hsp70) family is a major target of the humoral immune response during Leishmania donovani infection. A recombinant fusion protein was recognized by sera from 92% (35 of 38) of patients with visceral leishmaniasis, including representatives from each of the ...

journal_title：Infection and immunity

authors： Wallace GR,Ball AE,MacFarlane J,el Safi SH,Miles MA,Kelly JM

更新日期：1992-07-01 00:00:00

abstract：:Light and electron microscopy with histochemical staining were used to estimate exopolysaccharide production by strains of viridans streptococci recovered from patients with endocarditis. Six strains were selected for study because they represented a wide range of in vitro polysaccharide production. By light microscop...

journal_title：Infection and immunity

authors： Mills J,Pulliam L,Dall L,Marzouk J,Wilson W,Costerton JW

更新日期：1984-01-01 00:00:00

abstract：:A murine model system was established to study immune responses to the Pnu-Imune vaccine, which is made up of 23 different pneumococcal capsular polysaccharides. In this animal model, antibody-forming cell responses to 21 of 23 individual polysaccharides in the vaccine were detected. The Pnu-Imune vaccine elicited goo...

journal_title：Infection and immunity

authors： Garg M,Subbarao B

更新日期：1992-06-01 00:00:00

abstract：:Nasopharyngeal colonization is a necessary first step in the pathogenesis of Streptococcus pneumoniae. Using isolates containing defined mutations in the S. pneumoniae capsule locus, we found that expression of the capsular polysaccharide is essential for colonization by the type 2 strain D39 and the type 3 strains A6...

journal_title：Infection and immunity

authors： Magee AD,Yother J

更新日期：2001-06-01 00:00:00

abstract：:Studies with animal models have demonstrated that viral respiratory tract infections suppress bacterial clearance processes in the lung and that this alteration in host defenses appears to explain the excessive mortality from bacterial pneumonia during influenza epidemics. However, since the pathogenesis of postinflue...

journal_title：Infection and immunity

authors： Nugent KM,Pesanti EL

更新日期：1983-12-01 00:00:00

abstract：:One aspect in a broad spectrum of possible mechanisms of cariostatic reactions of fluoride is its interaction with the metabolism of oral bacteria. Information on the mechanisms and kinetics of fluoride inhibition of essential enzymes of the glycolytic pathway of the relevant bacteria is lacking. In this work, the iso...

journal_title：Infection and immunity

authors： Hüther FJ,Psarros N,Duschner H

更新日期：1990-04-01 00:00:00

abstract：:Relapsing fever is a rapidly progressive and severe septic disease caused by certain Borrelia spirochetes. The disease is divided into two forms, i.e., epidemic relapsing fever, caused by Borrelia recurrentis and transmitted by lice, and the endemic form, caused by several Borrelia species, such as B. duttonii, and tr...

journal_title：Infection and immunity

authors： Meri T,Cutler SJ,Blom AM,Meri S,Jokiranta TS

更新日期：2006-07-01 00:00:00

abstract：:Inflammatory mediators orchestrate the host immune and metabolic response to acute bacterial infections and mediate the events leading to septic shock. Tumor necrosis factor (TNF) has long been identified as one of the proximal mediators of endotoxin action. Recent studies have implicated peroxisome proliferator-activ...

journal_title：Infection and immunity

authors： Hill MR,Clarke S,Rodgers K,Thornhill B,Peters JM,Gonzalez FJ,Gimble JM

更新日期：1999-07-01 00:00:00

abstract：:In experimental visceral leishmaniasis, in which the tissue macrophage is the target, in vivo responsiveness to conventional chemotherapy (pentavalent antimony [Sb]) requires a T-cell-dependent mechanism. To determine if this mechanism involves gamma interferon (IFN-gamma)-induced activation and/or specific IFN-gamma-...

journal_title：Infection and immunity

authors： Murray HW,Delph-Etienne S

更新日期：2000-01-01 00:00:00

abstract：:Histophilus somni is capable of intracellular survival within professional phagocytic cells, but the mechanism of survival is not understood. The Fic motif within the direct repeat (DR1)/DR2 domains of the IbpA fibrillary network protein of H. somni is cytotoxic to epithelial and phagocytic cells, which may interfere ...

journal_title：Infection and immunity

authors： Pan Y,Tagawa Y,Champion A,Sandal I,Inzana TJ

更新日期：2018-11-20 00:00:00

abstract：:Groups of mice were immunized either subcutaneously or intranasally with purified Brucella melitensis lipopolysaccharide (LPS) or with LPS as a noncovalent complex with Neisseria meningitidis group B outer membrane protein (LPS-GBOMP). Control mice were inoculated with sterile saline. Two doses of vaccine were given 4...

journal_title：Infection and immunity

authors： Bhattacharjee AK,Izadjoo MJ,Zollinger WD,Nikolich MP,Hoover DL

更新日期：2006-10-01 00:00:00

abstract：:Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) by host cells and th...

journal_title：Infection and immunity

authors： Fang R,Hara H,Sakai S,Hernandez-Cuellar E,Mitsuyama M,Kawamura I,Tsuchiya K

更新日期：2014-06-01 00:00:00

abstract：:Several early nonspecific host defense mechanisms were examined in resistant (BALB/c) and susceptible (C3H/He) mice after intraperitoneal inoculation with Rickettsia tsutsugamushi strain Gilliam. Inflammatory exudates were formed in both mouse strains in response to rickettsial inoculation, but the inflammatory respon...

journal_title：Infection and immunity

authors： Nacy CA,Groves MG

更新日期：1981-03-01 00:00:00

abstract：:Serum antibody responses to toxic shock syndrome (TSS) toxin 1 (TSST-1) and staphylococcal enterotoxins A, B, and C were determined by western blot (immunoblot) analysis of acute- and convalescent-phase paired sera from 18 TSS- and 31 non-TSS-associated Staphylococcus aureus infections. Compared with non-TSS cases, se...

journal_title：Infection and immunity

authors： Whiting JL,Rosten PM,Chow AW

更新日期：1989-01-01 00:00:00

abstract：:We isolated a monoclonal antibody directed against the ferric complex of aerobactin purified from Escherichia coli KH576. This antibody, which we designated MAb AERO1, was identified as an immunoglobulin G, subtype 2. A competitive enzyme-linked immunosorbent assay with MAb AERO1 had a limit of 10 nM for the detection...

journal_title：Infection and immunity

authors： le Roy D,Expert D,Razafindratsita A,Deroussent A,Cosme J,Bohuon C,Andremont A

更新日期：1992-03-01 00:00:00

abstract：:To evaluate the role of complement in pneumococcal and staphylococcal pneumonia, we decomplemented rats with cobra venom factor and inoculated them intratracheally with Staphylococcus aureus or type 25 pneumococci. S. aureus produced a patchy bronchopneumonia in normal Sprague-Dawley or Lewis rats, and decomplementati...

journal_title：Infection and immunity

authors： Coonrod JD,Yoneda K

更新日期：1982-09-01 00:00:00

abstract：:The formation of water-insoluble glucan by extracellular glucosyltransferase from Streptococcus mutans 6715 found to be greatly stimulated by various mono- or divalent cations. An enzyme preparation, obtained by ethanol fractionation, was able to catalyze the formation of water-insoluble glucan from sucrose in the pre...

journal_title：Infection and immunity

authors： Mukasa H,Shimamura A,Tsumori H

更新日期：1979-03-01 00:00:00

abstract：:Antibodies against the class 4 outer membrane protein (OMP) from Neisseria meningitidis have been purified from sera from vaccinees immunized with the Norwegian meningococcal group B outer membrane vesicle vaccine. The human sera and purified antibodies reacted strongly with the class 4 OMP in immunoblots, whereas exp...

journal_title：Infection and immunity

authors： Rosenqvist E,Musacchio A,Aase A,Høiby EA,Namork E,Kolberg J,Wedege E,Delvig A,Dalseg R,Michaelsen TE,Tommassen J

更新日期：1999-03-01 00:00:00

abstract：:In general there is a poor correlation between serum lipopolysaccharide (LPS; the biologically active constituent of endotoxin) levels and mortality in septic patients. The objective of this study was to determine if chemical, structural, or biological differences among LPS from different clinical isolates of gram-neg...

journal_title：Infection and immunity

authors： Luchi M,Morrison DC

更新日期：2000-04-01 00:00:00

abstract：:Vibrio mimicus 61892, isolated in 1977 from a case of watery diarrhea in Bangladesh, produces an enterotoxin which possesses activity in Y-1 mouse adrenal cells and in rabbit ileal loops which is identical to the prototype cholera toxin (CT) produced by Vibrio cholerae 569B. The neutralization of the adrenal cell acti...

journal_title：Infection and immunity

authors： Spira WM,Fedorka-Cray PJ

更新日期：1983-11-01 00:00:00