Elevated levels of plasma homocysteine in postmenopausal women in Burkina Faso.

abstract：:The concentration of leukocyte elastase/alpha1-proteinase inhibitor complexes in plasma and polymorphonuclear neutrophil extracts, and plasma trypsin inhibitory capacity were determined in 88 patients with type 2 diabetes and 47 control subjects. Higher values of these variables were found in patients as compared to c...

journal_title：Clinical chemistry and laboratory medicine

authors： Piwowar A,Knapik-Kordecka M,Warwas M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The Cystic Fibrosis European Network, coordinated from within the Katholieke Universiteit Leuven, is the provider of the European cystic fibrosis external quality assessment (EQA) scheme. The network aimed to seek feedback from laboratories that participated in the cystic fibrosis scheme in order to improve ...

journal_title：Clinical chemistry and laboratory medicine

authors： Berwouts S,Dequeker E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Faecal immunochemical tests (FIT) are becoming widely used in colorectal cancer screening. Estimation of faecal haemoglobin concentration in a large group prompted an observational study on gender and age. METHODS:A single estimate of faecal haemoglobin concentration was made using quantitative automated im...

journal_title：Clinical chemistry and laboratory medicine

authors： McDonald PJ,Strachan JA,Digby J,Steele RJ,Fraser CG

更新日期：2011-12-07 00:00:00

abstract：BACKGROUND:External quality assessment/proficiency test (EQA/PT) organizers play an important role in monitoring the performance of HbA1c measurements. With increasing quality of the assays, HbA1c is increasingly used for diagnosis of diabetes and the demands on EQA/PT organizers themselves are rising constantly. EQA o...

journal_title：Clinical chemistry and laboratory medicine

authors： Kaiser P,Spannagl M,van Campenhout C,Lenga Y,Siebelder C,Weykamp C

更新日期：2016-11-01 00:00:00

abstract：:Soluble transferrin receptor (sTfR) is reported to be a reliable marker for the diagnosis of iron deficiency, especially when iron metabolism is influenced by inflammatory disorders such as infection, chronic inflammation and cancer-related anemia. In the present multicenter study the analytical performance of a recen...

journal_title：Clinical chemistry and laboratory medicine

authors： Kolbe-Busch S,Lotz J,Hafner G,Blanckaert NJ,Claeys G,Togni G,Carlsen J,Röddiger R,Thomas L

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Stone composition has changed substantially over the past decades in developed countries. We studied urinary stone composition in Tunisian children. METHODS:We studied 205 children ranging from 3 months to 16 years old age and who were diagnosed as having urinary stones (122 boys and 83 girls). Stone analys...

journal_title：Clinical chemistry and laboratory medicine

authors： Alaya A,Nouri A,Najjar MF

更新日期：2011-02-01 00:00:00

abstract：:Chronic rejection accounts for the greatest loss of renal allografts. HLA mismatching has been minimised by organ allocation and new immunosuppressive drugs have been employed, but the average cadaveric graft survival still does not exceed 12 years. Though the aetiology is multifactorial, one contributory factor for t...

journal_title：Clinical chemistry and laboratory medicine

authors： Gerstenkorn C,Robertson H,Mohamed MA,O'Donnell M,Ali S,Talbot D

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Recently published data identified bone-specific alkaline phosphatase (BALP) as a good marker of bone formation in different bone diseases and osteoporosis. Two methods are available for BALP determination: one measures enzyme activity, the other its mass concentration. We compared results for BALP activity ...

journal_title：Clinical chemistry and laboratory medicine

authors： Avbersek-Luznik I,Gmeiner Stopar T,Marc J

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The calibration of Jaffe method for serum creatinine using one serum-based standard complemented with artificial matrix compensating standard's Jaffe-interfering substances allows two-point calibration with results well comparable with enzymatic methods. METHOD:Spectrophotometry was used. RESULTS:Jaffe pro...

journal_title：Clinical chemistry and laboratory medicine

authors： Chromý V,Rozkosná K,Sedlák P

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Point of care (POC) assays for cardiac troponins I or T (cTnI or cTnT) may accelerate the diagnosis of patients with suspected acute coronary syndrome (ACS). However, their clinical utility according to the 0 h/3 h algorithm recommended by the European Society of Cardiology (ESC) for non-ST elevation myocard...

journal_title：Clinical chemistry and laboratory medicine

authors： Suh D,Keller DI,Hof D,von Eckardstein A,Gawinecka J

更新日期：2018-03-28 00:00:00

abstract：BACKGROUND:Transition from communications (abstracts) of an Argentinean congress and their publication as full papers was analyzed. No similar report was found for clinical laboratory in Latin America. METHODS:A total of 388 communications from five congresses were identified, and searches were performed on the intern...

journal_title：Clinical chemistry and laboratory medicine

authors： Martínez AM,Fink NE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Sequencing based mutation screening assays of genes encompassing large numbers of exons could be substantially optimized by multiplex PCR, which enables simultaneous amplification of many targets in one reaction. In the present study, a multiplex PCR protocol originally developed for fragment analysis was ev...

journal_title：Clinical chemistry and laboratory medicine

authors： Horn MP,Mäder-Heinemann G,Andrey G,Largiadèr CR

更新日期：2009-01-01 00:00:00

abstract：:Translational research and translational medicine (referred to hereafter as translational research) are interchangeable terms that underline the pressing need to translate into practical benefits for those affected by disease the extensive investments divested by the private and public sectors in biomedical research. ...

journal_title：Clinical chemistry and laboratory medicine

authors： Plebani M,Marincola FM

更新日期：2006-01-01 00:00:00

abstract：:Nitric oxide (NO) activates soluble guanylyl cyclase, which results in an increased synthesis of cyclic guanosine 3',5'-cyclic monophosphate (cGMP), smooth muscle relaxation and vasodilation. The heme group in soluble guanylyl cyclase binds NO and allosterically activates the catalytic site. In addition, a second allo...

journal_title：Clinical chemistry and laboratory medicine

authors： Nakane M

更新日期：2003-07-01 00:00:00

abstract：:Successful reduction of the risk of viral transmission via blood components has focused attention on the risk of transfusion-associated bacterial sepsis. The incidence of transfusion reactions due to bacteria is currently estimated at between 1 per 100,000 and 1 per 1,000,000 units in the case of packed red blood cell...

journal_title：Clinical chemistry and laboratory medicine

authors： Walther-Wenke G

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The immunoglobulin superfamily receptor translocation-associated 2 (IRTA2) gene encodes both membrane and secreted forms of the B-cell differentiation antigen (also identified as FcRH5). The membrane form is highly expressed on the surface of hairy cell leukemia (HCL) cells from patients. This study aimed to...

journal_title：Clinical chemistry and laboratory medicine

authors： Ise T,Kreitman RJ,Pastan I,Nagata S

更新日期：2006-01-01 00:00:00

abstract：:Background Quantification of plasma amino acids is key to the diagnosis of inherited defects of amino acid synthesis, catabolism and transport, many of which present as clinical emergencies. The utility of this test is limited by the long analysis time and subsequent inability of laboratories to provide results in rea...

journal_title：Clinical chemistry and laboratory medicine

authors： Carling RS,John K,Churchus R,Turner C,Dalton RN

更新日期：2020-04-28 00:00:00

abstract：:Activated protein C (APC), a natural anticoagulant, is formed from protein C by the action of the thrombin-thrombomodulin (TM) complex on the endothelial cell surface. Endothelial protein C receptor augments the activation of protein C by the thrombin/TM system. APC inactivates the activated form of coagulation factor...

journal_title：Clinical chemistry and laboratory medicine

authors： Okajima K

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:Mechanical manipulation of the prostate is a generally accepted interfering factor for the measurement of prostate-specific antigen (PSA). However, only few studies have focused on common daily mechanical manipulations, such as bicycle riding. Furthermore, physical exercise is also supposed to modulate PSA seru...

journal_title：Clinical chemistry and laboratory medicine

authors： Herrmann M,Scharhag J,Sand-Hill M,Kindermann W,Herrmann W

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Measurement of late-night salivary cortisol concentrations is increasingly used as a screening test in suspected Cushing's syndrome. Cortisol concentrations are typically extremely low in late-night samples and discordant assay-specific reference ranges have been reported. Therefore, the aim of our study was...

journal_title：Clinical chemistry and laboratory medicine

authors： Vogeser M,Durner J,Seliger E,Auernhammer C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA), an endogenous competitive inhibitor of nitric oxide synthase plays an important role in endothelial dysfunction processes. Recent studies have linked high ADMA levels with several pathological conditions. The interest as a marker of endothelial dysfunction has increased in...

journal_title：Clinical chemistry and laboratory medicine

authors： Gervasoni J,Bonelli F,Zuppi C,Zappacosta B,Mordente A,Calvani R,Persichilli S

更新日期：2011-09-06 00:00:00

abstract：BACKGROUND:Query fever (Q fever) is a zoonotic infection, caused by the intracellular Gram-negative coccobacillus Coxiella burnetii. From 2007 until 2010, a large Q fever outbreak has occurred in the Netherlands. We studied traditional and less common inflammation markers in seronegative and seropositive patients with ...

journal_title：Clinical chemistry and laboratory medicine

authors： Vissers E,de Jager CP,Hilbink M,Kusters R,van Gageldonk-Lafeber AB,Wever PC

更新日期：2012-02-04 00:00:00

abstract：BACKGROUND:To prospectively evaluate the role of procalcitonin (PCT) in detecting or excluding medullary thyroid carcinoma (MTC) among patients with thyroid nodules and increased calcitonin (CT) levels. METHODS:Fourteen of 1236 patients referred for thyroid nodules had increased serum CT >10 pg/mL. A stimulation test ...

journal_title：Clinical chemistry and laboratory medicine

authors： Giovanella L,Verburg FA,Imperiali M,Valabrega S,Trimboli P,Ceriani L

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:In recent years, fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG) in meconium emerged as reliable, direct biological markers for establishing gestational ethanol exposure. We investigated whether EtG in maternal hair measured during the three trimesters of pregnancy correlated with EtG and FAEEs i...

journal_title：Clinical chemistry and laboratory medicine

authors： Joya X,Marchei E,Salat-Batlle J,García-Algar O,Calvaresi V,Pacifici R,Pichini S

更新日期：2016-03-01 00:00:00

abstract：:Low-density lipoprotein (LDL) oxidation in vivo depends on lipid composition and on plasma antioxidant status. The aim of our study was to investigate the relationship between plasma lipid composition and LDL oxidation and, in particular, to explore whether LDL-cholesterol/triglycerides ratio (LDL-C/TG) and LDL-choles...

journal_title：Clinical chemistry and laboratory medicine

authors： Brizzi P,Tonolo G,Carusillo F,Malaguarnera M,Maioli M,Musumeci S

更新日期：2003-01-01 00:00:00

abstract：:The treatment of tuberculosis usually includes the antibiotic rifampicin, especially in patients with concomitant human immunodeficiency virus infection. Some of these patients are in withdrawal therapy for drug abuse. When opiate screening is carried out in patients receiving rifampicin, false positive results are de...

journal_title：Clinical chemistry and laboratory medicine

authors： de Paula M,Saiz LC,González-Revaldería J,Pascual T,Alberola C,Miravalles E

更新日期：1998-04-01 00:00:00

abstract：:Venous blood sampling (phlebotomy) is the most common invasive procedure performed in patient care. Guidelines on the correct practice of phlebotomy are available, including the H3-A6 guideline issued by the Clinical Laboratory Standards Institute (CLSI). As the quality of practices and procedures related to venous bl...

journal_title：Clinical chemistry and laboratory medicine

authors： van Dongen-Lases EC,Cornes MP,Grankvist K,Ibarz M,Kristensen GB,Lippi G,Nybo M,Simundic AM,Working Group for Preanalytical Phase (WG-PRE), European Federation of Clinical Chemistry and Laboratory Medicine (EFLM).

更新日期：2016-07-01 00:00:00

abstract：:Polymorphisms of the gene encoding apolipoprotein E have been implicated in the pathogenesis of peripheral and coronary artery disease and neurodegenerative disorders such as sporadic and late-onset familial forms of Alzheimer's disease. We have developed TaqMan assay systems for the single nucleotide polymorphisms -2...

journal_title：Clinical chemistry and laboratory medicine

authors： Koch W,Ehrenhaft A,Griesser K,Pfeufer A,Müller J,Schömig A,Kastrati A

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Automated systems for antinuclear antibody analysis are being introduced. The aim was to evaluate whether automated quantitative reading of fluorescence intensity is clinically relevant and allows for value-added reporting of test results. METHODS:Consecutive samples (n=260) were used to correlate fluoresce...

journal_title：Clinical chemistry and laboratory medicine

authors： Schouwers S,Bonnet M,Verschueren P,Westhovens R,Blockmans D,Mariën G,Bossuyt X

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Certain genetic polymorphisms can lead to differences in immunity function, resulting in different clinical outcomes for hepatitis B virus (HBV) patients. The aim of this study was to investigate the association between apolipoprotein E (ApoE) gene polymorphisms and HBV infection status in northern Chinese i...

journal_title：Clinical chemistry and laboratory medicine

authors： Yin Z,Xiong C,Wang Y,Zhou X,Yan SK

更新日期：2010-12-01 00:00:00