Abstract：
:We used the direct Fick measurements to validate a method for estimating cardiac output by iteratively fitting VCO(2) at the mouth to lung model values. This model was run using a series of 50, 30 and 10 breaths to test sensitivity to number of breaths used for fitting. The lung was treated as a catenary two-compartment lung model consisting of a dead space compartment connected with a single alveolar space compartment, perfused with constant pulmonary blood flow. The implemented mathematical modeling described variations in O(2) and CO(2) compartmental fractions and alveolar volume. This model also included pulmonary capillary gas exchange. Experimental data were collected from measurements performed on six healthy subjects at rest and during 20, 40, 60 and 85-90% of peak V(O)(2). The correlation between the two methods was highest and the average agreement between the methods was best using 50 breaths R = 095; P < 0.0001; Q(model) = 1.1Q(Fick) - 2.3). The mean difference and lower to upper limits of agreement between measured and estimated data were 0.7 l/min (-2.7 to 4.1 l/min) for cardiac output; -0.9 ml/100 ml (-1.3 to -0.5 ml/100 ml) for arterial O(2) content; -0.8 ml/100 ml (-3.8 to 2.2 ml/100 ml) for mixed venous O(2) content and -0.1 ml/100 ml (-2.9 to 2.7 ml/100 ml) for arteriovenous difference O(2) content. The cardiac output estimated by the lung model was in good agreement with the direct Fick measurements in young healthy subjects.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Benallal H,Beck KC,Johnson BD,Busso Tdoi
10.1007/s00421-005-1376-6keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
153-62issue
2-3eissn
1439-6319issn
1439-6327journal_volume
95pub_type
杂志文章abstract：:Measuring physical workload in occupational medicine is fundamental for risk prevention. An indirect measurement of total and relative energy expenditure (EE) from heart rate (HR) is widely used but it has never been validated. The aim of this study was to validate this HR-estimated energy expenditure (HREEE) method a...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
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更新日期：2005-05-01 00:00:00
abstract：:The aim of this study was to determine the timecourse of recovery of immunoendocrine responses following prolonged cycling. With the approval of the Ethics Committee, ten healthy men (age 21.6+/-0.9 years, height 1.77+/-0.01 m, body mass 66.9+/-1.8 kg, VO2max 54.2+/-2.0 ml kg(-1) min(-1); means+/-SEM) performed either...
journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
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更新日期：2016-10-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
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pub_type： 杂志文章,随机对照试验
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
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更新日期：2012-10-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
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更新日期：2007-01-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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更新日期：2004-01-01 00:00:00
abstract：:This article reviews human and animal studies about the circadian patterns of physiological variables involved with the respiratory function. Some measures reflecting the mechanical properties of the lungs, such as functional residual capacity, forced expiratory volumes and airway resistance, change periodically with ...
journal_title：European journal of applied physiology
pub_type： 杂志文章,评审
doi：10.1007/s00421-003-0978-0
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-007-0660-z
更新日期：2008-09-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-0060-1
更新日期：2006-01-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章,评审
doi：10.1007/s00421-017-3591-3
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-003-0891-6
更新日期：2003-08-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 历史文章,杂志文章,评审
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更新日期：2012-08-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-002-0587-3
更新日期：2002-05-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-014-3079-3
更新日期：2015-05-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2004-05-01 00:00:00
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journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-002-0655-8
更新日期：2002-08-01 00:00:00
abstract：:Muscle fiber conduction velocity (MFCV) has often been shown to decrease during standardized fatiguing isometric contractions. However, several studies have indicated that the MFCV may remain constant during fatiguing dynamic exercise. It was investigated if these observations can be related to the absence of a large ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-2119-5
更新日期：2012-05-01 00:00:00
