当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Myelination and long diffusion times alter diffusion-tensor-imaging contrast in myelin-deficient shiverer mice.

Myelination and long diffusion times alter diffusion-tensor-imaging contrast in myelin-deficient shiverer mice.

Abstract：

:Diffusion tensor imaging (DTI) using variable diffusion times (t(diff)) was performed to investigate wild-type (wt) mice, myelin-deficient shiverer (shi) mutant mice and shi mice transplanted with wt neural precursor cells that differentiate and function as oligodendrocytes. At t(diff) = 30 ms, the diffusion anisotropy "volume ratio" (VR), diffusion perpendicular to the fibers (lambda( perpendicular)), and mean apparent diffusion coefficient () of the corpus callosum of shi mice were significantly higher than those of wt mice by 12 +/- 2%, 13 +/- 2%, and 10 +/- 1%, respectively; fractional anisotropy (FA) and relative anisotropy (RA) were lower by 10 +/- 1% and 11 +/- 3%, respectively. Diffusion parallel to the fibers (lambda(//)) was not statistically different between shi and wt mice. Normalized T(2)-weighted signal intensities showed obvious differences (27 +/- 4%) between wt and shi mice in the corpus callosum but surprisingly did not detect transplant-derived myelination. In contrast, diffusion anisotropy maps detected transplant-derived myelination in the corpus callosum and its spatial distribution was consistent with the donor-derived myelination determined by immunohistochemical staining. Anisotropy indices (except lambda(//)) in the corpus callosum showed strong t(diff) dependence (30-280 ms), and the differences in lambda( perpendicular) and VR between wt and shi mice became significantly larger at longer t(diff), indicative of improved DTI sensitivity at long t(diff). In contrast, anisotropy indices in the hippocampus showed very weak t(diff) dependence and were not significantly different between wt and shi mice across different t(diff). This study provides insights into the biological signal sources and measurement parameters influencing DTI contrast, which could lead to developing more sensitive techniques for detection of demyelinating diseases.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Nair G,Tanahashi Y,Low HP,Billings-Gagliardi S,Schwartz WJ,Duong TQ

doi

10.1016/j.neuroimage.2005.05.049

keywords:

subject

Has Abstract

pub_date

2005-10-15 00:00:00

pages

165-74

issue

1

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(05)00386-1

journal_volume

28

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data.

    abstract：:Large amounts of multimodal neuroimaging data are acquired every year worldwide. In order to extract high-dimensional information for computational neuroscience applications standardized data fusion and efficient reduction into integrative data structures are required. Such self-consistent multimodal data sets can be ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.03.055

    authors： Schirner M,Rothmeier S,Jirsa VK,McIntosh AR,Ritter P

    更新日期：2015-08-15 00:00:00

  • Resting state network estimation in individual subjects.

    abstract：:Resting state functional magnetic resonance imaging (fMRI) has been used to study brain networks associated with both normal and pathological cognitive functions. The objective of this work is to reliably compute resting state network (RSN) topography in single participants. We trained a supervised classifier (multi-l...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.05.108

    authors： Hacker CD,Laumann TO,Szrama NP,Baldassarre A,Snyder AZ,Leuthardt EC,Corbetta M

    更新日期：2013-11-15 00:00:00

  • The dopamine D2 receptor gene DRD2 and the nicotinic acetylcholine receptor gene CHRNA4 interact on striatal gray matter volume: evidence from a genetic imaging study.

    abstract：:Dopaminergic activity is modulated by acetylcholine with relevance for cognitive functioning, as shown by pharmacological work in a rodent model. In humans, the two transmitter systems' joint effort on cognition has been described on the molecular genetic level: DRD2 rs6277, a single nucleotide polymorphism (SNP) on t...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.08.059

    authors： Markett S,Reuter M,Montag C,Weber B

    更新日期：2013-01-01 00:00:00

  • A novel quantitative cross-validation of different cortical surface reconstruction algorithms using MRI phantom.

    abstract：:Cortical surface reconstruction is important for functional brain mapping and morphometric analysis of the brain cortex. Several methods have been developed for the faithful reconstruction of surface models which represent the true cortical surface in both geometry and topology. However, there has been no explicit com...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.12.044

    authors： Lee JK,Lee JM,Kim JS,Kim IY,Evans AC,Kim SI

    更新日期：2006-06-01 00:00:00

  • The effect of gender on planning: An fMRI study using the Tower of London task.

    abstract：:Since the introduction of brain mapping, evidences of functional gender differences have been corroborating previous behavioral and neuropsychological results showing a sex-specific brain organization. We investigated gender differences in brain activation during the performance of the Tower of London (TOL) task which...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.07.022

    authors： Boghi A,Rasetti R,Avidano F,Manzone C,Orsi L,D'Agata F,Caroppo P,Bergui M,Rocca P,Pulvirenti L,Bradac GB,Bogetto F,Mutani R,Mortara P

    更新日期：2006-11-15 00:00:00

  • Piecemeal recruitment of left-lateralized brain areas during reading: a spatio-functional account.

    abstract：:Neuroimaging studies of reading converge to suggest that linguistically elementary stimuli are confined to the activation of bilateral posterior regions, whereas linguistically complex stimuli additionally recruit left hemispheric anterior regions, raising the hypotheses of a gradual bilateral-to-left and a posterior-...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.08.008

    authors： Levy J,Pernet C,Treserras S,Boulanouar K,Berry I,Aubry F,Demonet JF,Celsis P

    更新日期：2008-11-15 00:00:00

  • Commonalities and differences in predictive neural processing of discrete vs continuous action feedback.

    abstract：:Sensory action consequences are highly predictable and thus engage less neural resources compared to externally generated sensory events. While this has frequently been observed to lead to attenuated perceptual sensitivity and suppression of activity in sensory cortices, some studies conversely reported enhanced perce...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2021.117745

    authors： Schmitter CV,Steinsträter O,Kircher T,van Kemenade BM,Straube B

    更新日期：2021-01-14 00:00:00

  • Separating event-related BOLD components within trials: the partial-trial design revisited.

    abstract：:Many event-related fMRI designs involve multiple successive events occurring within a trial, spaced closely in time (e.g., in cued set-shifting paradigms). Yet, it is notoriously difficult to separate the activation components to these sequentially ordered events, given the long evolution time of the BOLD response. On...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.04.075

    authors： Ruge H,Goschke T,Braver TS

    更新日期：2009-08-15 00:00:00

  • Dynamic changes in the cerebral metabolic rate of O2 and oxygen extraction ratio in event-related functional MRI.

    abstract：:Dynamic changes in the cerebral metabolic rate of oxygen (CMRO(2)) and oxygen extraction ratio (OER) in an event-related functional MRI (ER-fMRI) were measured in this study. Six subjects participated in this study at a magnetic field of 1.9 T. Cerebral blood flow (CBF) and blood oxygenation level-dependent (BOLD) cha...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/s1053-8119(02)00023-x

    authors： Feng CM,Liu HL,Fox PT,Gao JH

    更新日期：2003-02-01 00:00:00

  • A study of the electro-haemodynamic coupling using simultaneously acquired intracranial EEG and fMRI data in humans.

    abstract：:In current fMRI studies designed to map BOLD changes related to interictal epileptiform discharges (IED), which are recorded on simultaneous EEG, the information contained in the morphology and field extent of the EEG events is exclusively used for their classification. Usually, a BOLD predictor based on IED onset tim...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.08.001

    authors： Murta T,Hu L,Tierney TM,Chaudhary UJ,Walker MC,Carmichael DW,Figueiredo P,Lemieux L

    更新日期：2016-11-15 00:00:00

  • The past tense debate: is phonological complexity the key to the puzzle?

    abstract：:Theorists disagree over whether our language faculty is a single system or a dual one. Those supporting the latter position believe that English regular and irregular past tense verbs reflect this duality, with some proposing that each is processed by a rule mechanism and memorised lexicon respectively. Single system ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.04.008

    authors： Oh TM,Tan KL,Ng P,Berne YI,Graham S

    更新日期：2011-07-01 00:00:00

  • Task-dependent activations of human auditory cortex during spatial discrimination and spatial memory tasks.

    abstract：:In the present study, we applied high-resolution functional magnetic resonance imaging (fMRI) of the human auditory cortex (AC) and adjacent areas to compare activations during spatial discrimination and spatial n-back memory tasks that were varied parametrically in difficulty. We found that activations in the anterio...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.10.069

    authors： Rinne T,Koistinen S,Talja S,Wikman P,Salonen O

    更新日期：2012-02-15 00:00:00

  • Individuals with schizophrenia present hypo- and hyperactivation during implicit cueing in an inhibitory task.

    abstract：BACKGROUND:The primary purpose of this investigation was to assess the neural correlates of implicit cueing during an inhibitory task in schizophrenia when performance accuracy was matched with healthy comparison subjects. METHODS:We compared 17 individuals with chronic schizophrenia (SZ; medicated, 13.9 average years...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.04.189

    authors： Arce E,Leland DS,Miller DA,Simmons AN,Winternheimer KC,Paulus MP

    更新日期：2006-08-15 00:00:00

  • Functional networks and network perturbations in rodents.

    abstract：:Synchronous low-frequency oscillation in the resting human brain has been found to form networks of functionally associated areas and hence has been widely used to map the functional connectivity of the brain using techniques such as resting-state functional MRI (rsfMRI). Interestingly, similar resting-state networks ...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2017.09.038

    authors： Chuang KH,Nasrallah FA

    更新日期：2017-12-01 00:00:00

  • A mini-cap for simultaneous EEG and fMRI recording in rodents.

    abstract：:Simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is now widely accepted as a prevailing tool to study brain functions. For over a decade, EEG caps with high-dense arrays of electrodes for EEG-fMRI studies in humans have been commercially available. However, simult...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.09.056

    authors： Sumiyoshi A,Riera JJ,Ogawa T,Kawashima R

    更新日期：2011-02-01 00:00:00

  • Brain functional development separates into three distinct time periods in the first two years of life.

    abstract：:Recently, resting functional MRI has provided invaluable insight into the brain developmental processes of early infancy and childhood. A common feature of previous functional development studies is the use of age to separate subjects into different cohorts for group comparisons. However, functional maturation paces v...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.01.025

    authors： Yin W,Chen MH,Hung SC,Baluyot KR,Li T,Lin W

    更新日期：2019-04-01 00:00:00

  • Gastric fundic distension activates fronto-limbic structures but not primary somatosensory cortex: a functional magnetic resonance imaging study.

    abstract：INTRODUCTION:The brain representation of visceral stimulation bears important similarities to that of somatic stimulation. However, the role of the primary (S1) and secondary (S2) somatosensory cortices in mediating gastric sensation is uncertain. MATERIALS AND METHODS:Eighteen healthy, right-handed volunteers (age 32...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.07.033

    authors： Ladabaum U,Roberts TP,McGonigle DJ

    更新日期：2007-01-15 00:00:00

  • Age mediation of frontoparietal activation during visual feature search.

    abstract：:Activation of frontal and parietal brain regions is associated with attentional control during visual search. We used fMRI to characterize age-related differences in frontoparietal activation in a highly efficient feature search task, detection of a shape singleton. On half of the trials, a salient distractor (a color...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.07.053

    authors： Madden DJ,Parks EL,Davis SW,Diaz MT,Potter GG,Chou YH,Chen NK,Cabeza R

    更新日期：2014-11-15 00:00:00

  • The activity in human areas V1/V2, V3, and V5 during the perception of coherent and incoherent motion.

    abstract：:We have used the technique of positron emission tomography to study and compare the cortical activity produced when humans view a pattern of small squares moving incoherently with respect to one another and when the same pattern moves coherently and unidirectionally. A stationary version of the stimulus acted as a con...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.1996.0246

    authors： McKeefry DJ,Watson JD,Frackowiak RS,Fong K,Zeki S

    更新日期：1997-01-01 00:00:00

  • ConnectomeDB--Sharing human brain connectivity data.

    abstract：:ConnectomeDB is a database for housing and disseminating data about human brain structure, function, and connectivity, along with associated behavioral and demographic data. It is the main archive and dissemination platform for data collected under the WU-Minn consortium Human Connectome Project. Additional connectome...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.04.046

    authors： Hodge MR,Horton W,Brown T,Herrick R,Olsen T,Hileman ME,McKay M,Archie KA,Cler E,Harms MP,Burgess GC,Glasser MF,Elam JS,Curtiss SW,Barch DM,Oostenveld R,Larson-Prior LJ,Ugurbil K,Van Essen DC,Marcus DS

    更新日期：2016-01-01 00:00:00

  • Trajectories of brain aging in middle-aged and older adults: regional and individual differences.

    abstract：:The human brain changes with age. However, the rate and the trajectories of change vary among the brain regions and among individuals, and the reasons for these differences are unclear. In a sample of healthy middle-aged and older adults, we examined mean volume change and individual differences in the rate of change ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.03.020

    authors： Raz N,Ghisletta P,Rodrigue KM,Kennedy KM,Lindenberger U

    更新日期：2010-06-01 00:00:00

  • DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging.

    abstract：PURPOSE:To examine the extent of genetic damage, assessed from deoxyribonucleic acid (DNA) double-strand breaks (DSBs) and micronuclei (MN) in peripheral blood mononuclear cells obtained from individuals repeatedly exposed to 7T Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS:The study protocol was approved by...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.03.023

    authors： Fatahi M,Reddig A,Vijayalaxmi,Friebe B,Hartig R,Prihoda TJ,Ricke J,Roggenbuck D,Reinhold D,Speck O

    更新日期：2016-06-01 00:00:00

  • Prefrontal activity during taste encoding: an fNIRS study.

    abstract：:To elucidate the function of the lateral prefrontal cortex (LPFC) in taste encoding, it is worth applying to taste, the psychological paradigms of intentional memorization that have been used with other extensively studied senses, and thus updating current models for LPFC functions to include a taste modality. Using m...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.12.021

    authors： Okamoto M,Matsunami M,Dan H,Kohata T,Kohyama K,Dan I

    更新日期：2006-06-01 00:00:00

  • Supervoxel-based statistical analysis of diffusion tensor imaging in schizotypal personality disorder.

    abstract：:To study white matter changes in schizotypal personality disorder (SPD), we developed a new statistical analysis method based on supervoxels for diffusion tensor imaging. Twenty patients with SPD and eighteen healthy controls were recruited from a pool of 3000 first-year university undergraduates, and underwent MRI us...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.07.026

    authors： Zhang T,Wang D,Zhang Q,Wu J,Lv J,Shi L

    更新日期：2017-12-01 00:00:00

  • Neuroanatomical substrates involved in true and false memories for face.

    abstract：:We often mistake an unknown person for a familiar person because of the similarities in facial features. This phenomenon, known as false memory, has been investigated mainly using words, pictures, and shapes. Previous neuroimaging studies on false memory have shown that both true and false memories trigger a similar a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.04.044

    authors： Iidaka T,Harada T,Kawaguchi J,Sadato N

    更新日期：2012-08-01 00:00:00

  • Single-scan R₂(*) measurement with macroscopic field inhomogeneity correction.

    abstract：:Accurate quantification of R₂(*) (=1/T₂(*)) is important for many applications in neuroimaging. However, R₂(*) measurements made using conventional multi-echo gradient echo imaging are hampered by macroscopic field inhomogeneities. Several methods for compensation of macroscopic field inhomogeneities have been introdu...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.08.062

    authors： Nam Y,Han D,Kim DH

    更新日期：2012-12-01 00:00:00

  • Cognitive reward control recruits medial and lateral frontal cortices, which are also involved in cognitive emotion regulation: A coordinate-based meta-analysis of fMRI studies.

    abstract：:Cognitive reward control (CRC) refers to the cognitive control of one's craving for hedonic stimuli, like food, sex, or drugs. Numerous functional magnetic resonance imaging (fMRI) studies have investigated neural sources of CRC. However, a consistent pattern of brain activation across stimulus types has not been iden...

    journal_title：NeuroImage

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.neuroimage.2019.07.008

    authors： Brandl F,Le Houcq Corbi Z,Mulej Bratec S,Sorg C

    更新日期：2019-10-15 00:00:00

  • The effect of switching between sequential and repetitive movements on cortical activation.

    abstract：:We used whole-head functional magnetic resonance imaging (fMRI) to investigate the effect of switching between different sequential and repetitive movements in the context of conditional and fixed tasks. Four different movement tasks were applied: (1) unpredictable switching between two movement sequences comprising s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2000.0626

    authors： Jäncke L,Himmelbach M,Shah NJ,Zilles K

    更新日期：2000-11-01 00:00:00

  • Acute immobilisation facilitates premotor preparatory activity for the non-restrained hand when facing grasp affordances.

    abstract：:Use and non-use of body parts during goal-directed action are major forces driving reorganisation of neural processing. We investigated changes in functional brain activity resulting from acute short-term immobilisation of the dominant right hand. Informed by the concept of object affordances, we predicted that the pr...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.02.003

    authors： Kühn S,Werner A,Lindenberger U,Verrel J

    更新日期：2014-05-15 00:00:00

  • Genetic influences on prefrontal activation during a verbal fluency task in adults: a twin study based on multichannel near-infrared spectroscopy.

    abstract：:Near-infrared spectroscopy (NIRS) studies have reported that prefrontal hemodynamic dysfunction during executive function tasks may be a promising biomarker of psychiatric disorders, because its portability and noninvasiveness allow easy measurements in clinical settings. Here, we investigated the degree to which pref...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.03.052

    authors： Sakakibara E,Takizawa R,Nishimura Y,Kawasaki S,Satomura Y,Kinoshita A,Koike S,Marumo K,Kinou M,Tochigi M,Nishida N,Tokunaga K,Eguchi S,Yamasaki S,Natsubori T,Iwashiro N,Inoue H,Takano Y,Takei K,Suga M,Yamasue H,

    更新日期：2014-01-15 00:00:00