Abstract:
:The relationship between neocortical structure and function is a key area of research in neuroscience. Most studies of neural function, whether using neurophysiology or neuroimaging methods, are interpreted with relation to the underlying cortical myelo- and cytoarchitecture. For functional neuroimaging studies this often means using cytoarchitectonic maps based on the study of a limited number of brains, despite evidence for substantial interindividual variation. Improvements in MR technology, resulting in wider availability of high-field MRI systems, have led to an increase in the achievable resolution in MR scans. Several groups have reported the in vivo detection of myelination patterns within the cortex, consistent with those observed in postmortem tissue. This leads to the possibility of predefining areas for fMRI analysis based on the cortical architecture. To do this it is essential to know, in a quantitative way, how reliably myeloarchitectonic areas and boundaries can be detected using MRI. Here we investigate the striate cortex, known to be coincident with V1, to assess the detectability of the stria of Gennari across V1 and across subjects. Under optimal conditions, 80% of the stria of Gennari was visualized using our methodology, although there was considerable variability in the level of detection across subjects. We discuss the limitations of the methodology and propose ways to improve the detection level of cortical myeloarchitecture more generally.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Clare S,Bridge Hdoi
10.1002/hbm.20162keywords:
subject
Has Abstractpub_date
2005-12-01 00:00:00pages
240-50issue
4eissn
1065-9471issn
1097-0193journal_volume
26pub_type
杂志文章abstract::The sulcal morphology of the human frontal lobe is highly variable. Although the structural images usually acquired in functional magnetic resonance imaging studies provide information about this interindividual variability, this information is only rarely used to relate structure and function. Here, we investigated t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20501
更新日期:2009-01-01 00:00:00
abstract::Impairment in controlled semantic association is a central feature of schizophrenia, and the goal of the current functional magnetic resonance imaging study was to identify the neural correlates of this impairment. Thirty people with schizophrenia and 30 healthy age- and gender-matched control subjects performed a tas...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22820
更新日期:2015-08-01 00:00:00
abstract::It is becoming common to collect data from multiple functional magnetic resonance imaging (fMRI) paradigms on a single individual. The data from these experiments are typically analyzed separately and sometimes directly subtracted from one another on a voxel-by-voxel basis. These comparative approaches, although usefu...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20204
更新日期:2006-07-01 00:00:00
abstract::One of our highest evolved functions as human beings is our capacity to switch between multiple tasks effectively. A body of research has identified a distributed frontoparietal network of brain regions which contribute to task switching. However, relatively less is known about whether some brain regions may contribut...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析
doi:10.1002/hbm.21199
更新日期:2012-01-01 00:00:00
abstract::The ability of functional MRI to acquire data from multiple brain areas has spurred developments not only in voxel-by-voxel analyses, but also in multivariate techniques critical to quantifying the interactions between brain areas. As the number of multivariate techniques multiplies, however, few studies in any modali...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20771
更新日期:2009-11-01 00:00:00
abstract::Neuroimaging studies provide evidence for organized intrinsic activity under task-free conditions. This activity serves functionally relevant brain systems supporting cognition. Here, we analyze changes in resting-state functional connectivity after videogame practice applying a test-retest design. Twenty young female...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22129
更新日期:2013-12-01 00:00:00
abstract::The new clinically available arterial spin labeling (ASL) perfusion imaging sequences present some advantages relatively to the commonly used blood oxygen level-dependent (BOLD) method for functional brain studies using magnetic resonance imaging (MRI). In particular, regional cerebral blood flow (CBF) changes are tho...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.21418
更新日期:2013-01-01 00:00:00
abstract::Both increases and decreases in resting state functional connectivity have been previously observed within the motor network during aging. Moreover, the relationship between altered functional connectivity and age-related declines in bimanual coordination remains unclear. Here, we explored the developmental dynamics o...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22450
更新日期:2014-08-01 00:00:00
abstract::The central extended amygdala (EAc)-including the bed nucleus of the stria terminalis (BST) and central nucleus of the amygdala (Ce)-plays a critical role in triggering fear and anxiety and is implicated in the development of a range of debilitating neuropsychiatric disorders. Although it is widely believed that these...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23917
更新日期:2018-03-01 00:00:00
abstract::Electrophysiological and neuroimaging studies suggest that the integrity of ipsilesional and inter-hemispheric motor circuits is important for motor recovery after stroke. However, the extent to which each of these tracts contributes to the variance in outcome remains unclear. We examined whether diffusion tensor imag...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21266
更新日期:2012-05-01 00:00:00
abstract::Surface deformation-based analysis was used to assess local shape variations in the hippocampi and caudate nuclei of children with fetal alcohol spectrum disorders. High-resolution structural magnetic resonance imaging images were acquired for 31 children (19 controls and 12 children diagnosed with fetal alcohol syndr...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22209
更新日期:2014-02-01 00:00:00
abstract::Past research has found that neural activity associated with feedback processing is enhanced by positive approach-motivated states. However, no past work has examined how reward processing changes in the context of revenge. Using a novel aggression paradigm, we sought to explore the influence of approach-motivated ang...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25177
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intravascular angioplasty and stenting of intracranial arterial stenosis provided controversial results. Besides the expertise of the practitioners, the selection of the patients remains challenging. BOLD MRI of the cerebral vasoreactivity (BOLD MRI CVR) to hypercapnia provides reproducible maps ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22255
更新日期:2014-04-01 00:00:00
abstract::Studying how the timing and amplitude of visual evoked responses (VERs) vary between visual areas is important for understanding visual processing but is complicated by difficulties in reliably estimating VERs in individual visual areas using noninvasive brain measurements. Retinotopy constrained source estimation (RC...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22293
更新日期:2014-05-01 00:00:00
abstract::Functional imaging studies consistently find that emotional stimuli activate the posterior cingulate cortex, a region that appears to have memory-related functions. However, prior imaging studies have not controlled for non-emotional stimulus features that might activate this region by engaging memory processes unrela...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10075
更新日期:2003-01-01 00:00:00
abstract::The literature points to a large distributed brain network involved in the estimation of time. Among these regions, the role of the insular cortex is still poorly understood. At the confluence of emotional, interoceptive, and environmental signals, this brain structure has been proposed to underlie awareness of the pa...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24460
更新日期:2019-04-01 00:00:00
abstract::Glucose transporter type I deficiency syndrome (GLUT1DS) is an encephalopathic disorder due to a chronic insufficient transport of glucose into the brain. PET studies in GLUT1DS documented a widespread cortico-thalamic hypometabolism and a signal increase in the basal ganglia, regardless of age and clinical phenotype....
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24815
更新日期:2020-02-01 00:00:00
abstract::Human neuroimaging studies have increasingly converged on the possibility that the neural representation of specific numbers may be decodable from brain activity, particularly in parietal cortex. Multivariate machine learning techniques have recently demonstrated that the neural representation of individual concrete n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22087
更新日期:2013-10-01 00:00:00
abstract::The BrainMap database is a community resource that curates peer-reviewed, coordinate-based human neuroimaging literature. By pairing the results of neuroimaging studies with their relevant meta-data, BrainMap facilitates coordinate-based meta-analysis (CBMA) of the neuroimaging literature en masse or at the level of e...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24078
更新日期:2018-08-01 00:00:00
abstract::Alterations in resting-state networks (RSNs) are often associated with psychiatric and neurologic disorders. Given this critical linkage, it has been hypothesized that RSNs can potentially be used as endophenotypes for brain diseases. To validate this notion, a critical step is to show that RSNs exhibit heritability. ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22890
更新日期:2015-10-01 00:00:00
abstract::Own body perception, and differentiating and comparing one's body to another person's body, are common cognitive functions that have relevance for self-identity and social interactions. In several psychiatric conditions, including anorexia nervosa, body dysmorphic disorder, gender dysphoria, and autism spectrum disord...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24388
更新日期:2019-02-01 00:00:00
abstract::Everyday communication is accompanied by visual information from several sources, including co-speech gestures, which provide semantic information listeners use to help disambiguate the speaker's message. Using fMRI, we examined how gestures influence neural activity in brain regions associated with processing semanti...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20774
更新日期:2009-11-01 00:00:00
abstract::The functional role of the left ventral occipito-temporal cortex (vOT) in visual word processing has been studied extensively. A prominent observation is higher activation for unfamiliar but pronounceable letter strings compared to regular words in this region. Some functional accounts have interpreted this finding as...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22281
更新日期:2014-04-01 00:00:00
abstract::Hypercoupling of activity in speech-perception-specific brain networks has been proposed to play a role in the generation of auditory-verbal hallucinations (AVHs) in schizophrenia; however, it is unclear whether this hypercoupling extends to nonverbal auditory perception. We investigated this by comparing schizophreni...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23934
更新日期:2018-04-01 00:00:00
abstract::Cognitive processing speed is crucial for human cognition and declines with aging. White matter hyperintensity (WMH), a common sign of WM vascular damage in the elderly, is closely related to slower psychomotor processing speed. In this study, we investigated the association between WMH and psychomotor speed changes t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24826
更新日期:2020-02-15 00:00:00
abstract::With the causes of perinatal brain injuries still unclear and the probable role of hemodynamic instability in their etiology, bedside monitoring of neonatal cerebral hemodynamics with standard values as a function of age are needed. In this study, we combined quantitative frequency domain near infrared spectroscopy (F...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20868
更新日期:2010-03-01 00:00:00
abstract::Though fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorders are among the most common developmental disorders, their understanding is incomplete. Diffusion tensor imaging (DTI), which is sensitive to microstructural organization in white matter, may provide a relevant measure in this population demonstrat...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20747
更新日期:2009-10-01 00:00:00
abstract::Few studies have examined the neural correlates of emotion regulation across adolescence and young adulthood. Existing studies of cognitive reappraisal indicate that improvements in regulatory efficiency may develop linearly across this period, in accordance with maturation of prefrontal cortical systems. However, the...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22905
更新日期:2016-01-01 00:00:00
abstract::It is widely accepted that abnormalities in the frontal area of the brain underpin the pathophysiology of obsessive-compulsive disorder (OCD). Fundamental to this investigation is the delineation of frontal white matter tracts including dorsal and ventral frontal projections of interhemispheric connections. While prev...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21372
更新日期:2012-10-01 00:00:00
abstract::Demyelination and axonal damage are pathologic hallmarks of multiple sclerosis (MS), leading to loss of neuronal synchronization, functional disconnection amongst brain relays, and clinical sequelae. To investigate these properties, the primary component of the sensorimotor network was analyzed in mildly disabled Rela...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.20961
更新日期:2010-10-01 00:00:00