Dynamics of real time DPOAE contralateral suppression in chinchillas and humans.

Abstract:

:The dynamics of contralateral acoustic suppression were studied using real time (millisecond resolution) distortion product otoacoustic emissions (DPOAEs) in chinchillas and humans. Latency of DPOAE suppression onset is 26 ms in chinchillas and 45 ms in humans. After onset, suppression builds over time before tending to plateau, reflecting a temporal integration process with a time constant of 100 ms (chinchillas). In chinchillas, suppression persists for 40 ms even when elicited by stimuli as short as 5 ms. With stimuli >40 ms, offset and onset latencies are similar and duration of suppression equals that of the contralateral stimulus. A comparison of DPOAE suppression onset latency with neural latency data from the pathways involved suggests the following timing scheme: stimulus onset to activity in (ventral) cochlear nucleus, 4ms (15% of delay); transfer to olivocochlear efferents, 9 ms (35%); efferent conduction to presynaptic OHC site, 4ms (15%); synaptic and mechanical events at OHCs, 9 ms (35% of delay).

journal_name

Int J Audiol

authors

James AL,Harrison RV,Pienkowski M,Dajani HR,Mount RJ

doi

10.1080/14992020400029996

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

118-29

issue

2

eissn

1499-2027

issn

1708-8186

journal_volume

44

pub_type

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