Abstract:
:The aim of this study was to evaluate, in 20 young volunteer subjects, the effects of supra-physiological vitamin B12 administration on noise-induced temporary threshold shift (TTS). All subjects had hearing thresholds within 15 dBHL and type A tympanograms. The subjects were randomly assigned to two different groups. Experimental group subjects received cyanocobalamin, 1 mg daily for 7 days, and 5 mg on the eighth day. Control group subjects received a placebo injection daily for 8 days. The vitamin B12 concentration, hearing thresholds and TTS2 (10 min of exposure, narrowband noise centred at 3 kHz, bandwidth of 775 Hz, 112 dBSPL) were measured before and 8 days after treatment. At the end of treatment, the serum vitamin B12 concentration was significantly increased in the experimental group. After 8 days of treatment, the control group showed the same hearing thresholds and TTS2 degrees. Statistical analysis showed that TTS2 decreased significantly at 3 and 4kHz when cobalamin was used to increase the serum concentration of vitamin B12 to > 2350 pg/ml. In addition, a protective effect at 3 kHz in the experimental group was evident when compared with the placebo group. These results suggest that elevated plasma cyanocobalamin levels may reduce the risk of hearing dysfunction resulting from noise exposure in healthy, young subjects.
journal_name
Int J Audioljournal_title
International journal of audiologyauthors
Quaranta A,Scaringi A,Bartoli R,Margarito MA,Quaranta Ndoi
10.1080/14992020400050022keywords:
subject
Has Abstractpub_date
2004-03-01 00:00:00pages
162-5issue
3eissn
1499-2027issn
1708-8186journal_volume
43pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:Deaf children with cochlear implants (CIs) show poorer verbal working memory compared to normal-hearing (NH) peers, but little is known about their verbal learning and memory (VLM) processes involving multi-trial free recall. DESIGN:Children with CIs were compared to NH peers using the California Verbal Lear...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2018.1481538
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Recent retrospective studies report differences in auditory neurophysiology between concussed athletes and uninjured controls using the frequency-following response (FFR). Adopting a prospective design in college football players, we compared FFRs before and after a concussion and evaluated test-retest relia...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2020.1860261
更新日期:2021-01-13 00:00:00
abstract::In 1997, Don and his co-workers described a new method for evaluating the auditory brainstem response (ABR)--yielding the stacked-wave-V ABR--which may permit the reliable detection of even small vestibular schwannomas (VSs). However, this method requires a masking technique that may not be readily available to the cl...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992020309078338
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:Music perception and appraisal are generally poor in cochlear implant recipients. Simple musical structures, lyrics that are easy to follow, and clear rhythm/beat have been reported among the top factors to enhance music enjoyment. The present study investigated the preference for modified relative instrument...
journal_title:International journal of audiology
pub_type: 临床试验,杂志文章
doi:10.3109/14992027.2013.873955
更新日期:2014-05-01 00:00:00
abstract::Objective: To create a language independent version of the Listening in Spatialised Noise - Sentences test (LiSN-S) and evaluate it in an English-speaking population.Design: Test development and normative data collection. LiSN-Universal (LiSN-U) targets consisted of CVCV pseudo-words (e.g. /mupa/). Two looped distract...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2019.1689431
更新日期:2020-04-01 00:00:00
abstract::Children with dichotic left ear deficits received intensive training in phase I and phase II clinical trials designed to establish the efficacy of directly training dichotic listening. Dichotic verbal material was presented in the sound field with intensity adjusted separately for each speaker. Output from the right-s...
journal_title:International journal of audiology
pub_type: 杂志文章,多中心研究
doi:10.1080/14992020701770835
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to explore the use of virtual visits to monitor hearing aid use with data logging measurements and provide parent support for hearing aid management. DESIGN:A 6-month longitudinal case study design was used. STUDY SAMPLE:Four families and two providers participated. RESULTS:Av...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2016.1226521
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To report the prevalence of hearing loss (HL) and associated factors in a nationwide study. DESIGN:Cross-sectional study. STUDY SAMPLE:We investigated the prevalence of HL in 10,845 participants ≥12 years of age and analysed the associated factors with HL from 7434 participants ≥40 years of age. RESULTS:Th...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2017.1373866
更新日期:2017-12-01 00:00:00
abstract::The dynamics of contralateral acoustic suppression were studied using real time (millisecond resolution) distortion product otoacoustic emissions (DPOAEs) in chinchillas and humans. Latency of DPOAE suppression onset is 26 ms in chinchillas and 45 ms in humans. After onset, suppression builds over time before tending ...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020400029996
更新日期:2005-02-01 00:00:00
abstract::The purpose was to investigate the relationship between noise exposure and tinnitus among workers with normal hearing and hearing loss, respectively. We conducted a cross-sectional survey of 752 workers employed at 91 workplaces, that were investigated by means of full work-shift noise levels, questionnaire data, and ...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020701581430
更新日期:2008-03-01 00:00:00
abstract::The fitting of a cochlear implant together with aided residual hearing was evaluated by means of matching frequency and/or perceived pitch between acoustic and electric modalities. Five cochlear implant users with the Nucleus Freedom electrode array with residual acoustic hearing participated. Psychophysical procedure...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020802452184
更新日期:2009-02-01 00:00:00
abstract::The aim of this study was to investigate long-term development of hearing in subjects who had received platinum-based chemotherapy in childhood or adolescence. Another aim was to assess the self-reported hearing loss handicap and compare it to audiometric measurements. Medical records from individuals diagnosed with c...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2010.485595
更新日期:2010-10-01 00:00:00
abstract::In this study, we present a new method to derive a single-number measure of the directivity of hearing aids. The method is an extension of the conventional directivity index (DI), and is called overall directivity index (ODI). The directivities of five different hearing aid styles were compared with that of the open e...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992020209101312
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:This paper reports a consanguineous deaf family with three different mutations in the GJB2 gene. DESIGN:Four members of an Iranian deaf family were recruited in this study. The GJB2 coding region and exon-intron boundaries were investigated using direct sequencing. STUDY SAMPLE:The proposita was a 12-year-o...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2013.850748
更新日期:2014-02-01 00:00:00
abstract::Objective: To identify any change in quality of life (QoL) caused by chemotherapy-induced toxicities, such as hearing loss and tinnitus, to provide information in order to improve services and aid clinicians in their decision-making. Design: This systematic review followed the preferred reporting items for systematic ...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2019.1660918
更新日期:2019-11-01 00:00:00
abstract::Post-auricular muscle responses (PAMRs) were recorded in sixteen adults with normal hearing and twenty adults with sensorineural hearing loss. Click stimuli were presented at 20 to 80 dB nHL via insert earphones. Only one ear was tested in hearing-impaired subjects, but normal-hearing subjects were tested monaurally a...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020500266639
更新日期:2005-11-01 00:00:00
abstract::The aim of the present study was to investigate the consequences of chronic otitis media on inner ear function. Retrospective analysis of conventional pure-tone audiometry tests was carried out on 344 patients who were scheduled for surgical treatment of unilateral chronic otitis media without other risk factors for s...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020500243737
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:Previous studies show that intracochlear electrical stimulation independent of environmental sounds appears to suppress tinnitus, even long-term. In order to assess the viability of this potential treatment option it is essential to study the effects of this tinnitus specific electrical stimulation on speech...
journal_title:International journal of audiology
pub_type: 杂志文章,随机对照试验
doi:10.1080/14992027.2017.1408964
更新日期:2018-06-01 00:00:00
abstract::The aim of this study was to compare auditory functions and to analyse the prevalence of hearing impairment and the relationship of self-reported hearing disability with audiometric test results among 75-year-old people in three Nordic localities. The representative samples came from Glostrup, Denmark (n = 571), Göteb...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020500189112
更新日期:2005-09-01 00:00:00
abstract::The purpose of this research was to investigate the congruent/incongruent perceptions of hearing-loss related quality of life between members of couples and to determine how incongruence was affected by individual psychosocial characteristics, specifically measures of mood (negative affect and positive affect), stress...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992020903311396
更新日期:2010-04-01 00:00:00
abstract::Tympanometry using 226 Hz, 678 Hz, and 1000 Hz probe tones was undertaken on two groups of babies, age 2 to 21 weeks. A group of 104 babies with normal ABR thresholds or TEOAEs were compared with a second group of 107 babies who had evidence of temporary conductive hearing loss based on the findings of a test battery,...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020600690951
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:The current study investigates the extent to which the linguistic complexity of three commonly employed speech recognition tests and second language proficiency influence speech recognition thresholds (SRTs) in noise in non-native listeners. DESIGN:SRTs were measured for non-natives and natives using three G...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2015.1063715
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:This study investigated the factors influencing 5-year language, speech and everyday functioning of children with congenital hearing loss. DESIGN:Standardised tests including PLS-4, PPVT-4 and DEAP were directly administered to children. Parent reports on language (CDI) and everyday functioning (PEACH) were ...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2017.1370140
更新日期:2018-05-01 00:00:00
abstract::Humans use several cues to determine the position of sound sources in space. Here we provide a review of the literature on how practice influences sound-localization performance in human adults. We divided this literature into two categories: adaptation to alterations in sound-localization cues and learning with norma...
journal_title:International journal of audiology
pub_type: 杂志文章,评审
doi:10.1080/14992020600783004
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To determine the usage and knowledge of safe limits on personal listening devices (PLD) among college students. DESIGN:First, information on health history was collected. Second, microphone in real ear techniques determined eardrum to free-field correction factors. Third, hearing levels were evaluated and in...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2014.986691
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:A significant relationship between dietary nutrient intake and susceptibility to acquired hearing loss is emerging. Variability in the outcomes across studies is likely related to differences in the specific metrics used to quantify nutrient intake and hearing status. Most studies have used single nutrient an...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2013.780133
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To examine parents' recollections of and their experiences with bringing up a child diagnosed with hearing loss at a very young age. DESIGN:Based on the analysis of informal parent discussion groups, four open-ended questions were formulated to solicit information about parents' expectations following diagno...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.3109/14992027.2013.825051
更新日期:2013-12-01 00:00:00
abstract::The real-ear insertion response (REIR) of a hearing aid is estimated as the difference between the aided response and the unaided response in the ear canal. Changes in the position of the loudspeaker relative to the head, between the two measurements, may reduce the accuracy of the estimate. The spatial variability of...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020400050036
更新日期:2004-05-01 00:00:00
abstract::Speech-in-noise audiometry has potential application as a low-cost, self-screening test for sensorineural hearing loss. To realize this potential, the influence of variations in audio equipment and listening environment need assessment. The present study assessed: 1) the frequency response and distortion produced by a...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992020500267017
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVE:The main purpose of this research was to obtain normative data for auditory processing tests for Norwegian speaking children. DESIGN:Participants were administered routine audiological tests and an auditory processing test-battery consisting of Filtered Words, Competing Words, Dichotic Digits, Gaps In Noise,...
journal_title:International journal of audiology
pub_type: 杂志文章
doi:10.1080/14992027.2017.1366670
更新日期:2018-01-01 00:00:00