Abstract:
:A brief description is given of neurofibrillary changes of the paired helical filament type in a variety of chronic neurological diseases. These include subacute sclerosing panencephalitis, lead encephalopathy, tuberous sclerosis, Down syndrome, Hallervorden-Spatz disease, and lipofuscinosis. In these conditions, with the exception of Hallervorden-Spatz disease neurofibrillary changes were previously recognized but paired helical filaments were identified only in some cases. Moreover, in the present series, the age of patients at death was often younger than in previously recorded cases.
journal_name
Ann Neuroljournal_title
Annals of neurologyauthors
Wisniewski K,Jervis GA,Moretz RC,Wisniewski HMdoi
10.1002/ana.410050311keywords:
subject
Has Abstractpub_date
1979-03-01 00:00:00pages
288-94issue
3eissn
0364-5134issn
1531-8249journal_volume
5pub_type
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journal_title:Annals of neurology
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pub_type: 杂志文章,随机对照试验
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doi:10.1002/ana.410200604
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journal_title:Annals of neurology
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更新日期:1997-02-01 00:00:00
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doi:10.1002/ana.410190117
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更新日期:1980-11-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.410090407
更新日期:1981-04-01 00:00:00
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doi:10.1002/ana.10613
更新日期:2003-08-01 00:00:00
abstract::Creutzfeldt-Jakob disease (CJD) is a rare dementia that is generally found in older people and is caused by unusual infectious pathogens or prions. Using rabbit antisera raised against hamster scrapie prion proteins (HaPrPSc), we identified by immunoblotting human CJD prion proteins (HuPrPCJD) in the brains of 14 pati...
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doi:10.1002/ana.410210611
更新日期:1987-06-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,随机对照试验
doi:10.1002/ana.22444
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:Wide interindividual variability exists in response to tissue plasminogen activator (t-PA) treatment in the acute phase of ischemic stroke. We aimed to find genetic variations associated with hemorrhagic transformation (HT) and mortality rates after t-PA. We then generated a clinical-genetic model for predict...
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doi:10.1002/ana.23664
更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.20365
更新日期:2005-02-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,meta分析
doi:10.1002/ana.20017
更新日期:2004-04-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.10094
更新日期:2002-02-01 00:00:00
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doi:10.1002/ana.24299
更新日期:2015-01-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/1531-8249(199905)45:5<659::aid-ana16>3.0.c
更新日期:1999-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.410210510
更新日期:1987-05-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.23824
更新日期:2013-04-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410440604
更新日期:1998-12-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410380107
更新日期:1995-07-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410250609
更新日期:1989-06-01 00:00:00
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更新日期:2009-06-01 00:00:00
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更新日期:2006-10-01 00:00:00