Role of infection in Guillain-Barré syndrome: laboratory confirmation of herpesviruses in 41 cases.

abstract：:Most clinically demented elderly patients are found at autopsy to have Alzheimer's disease, multi-infarct dementia, Parkinson's disease, Pick's disease, or Creutzfeldt-Jakob disease. We studied 5 patients clinically characterized by late onset dementia whose brains showed no pathological evidence of Alzheimer's diseas...

journal_title：Annals of neurology

authors： Masliah E,Hansen LA,Quijada S,DeTeresa R,Alford M,Kauss J,Terry R

更新日期：1991-04-01 00:00:00

abstract：:A number of reports have suggested an increasing incidence of primary brain tumors, especially malignant astrocytomas, in the elderly population. To investigate this issue, we analyzed the incidence and temporal trends of primary intracranial neoplasms diagnosed in the population of Rochester, Minnesota, over the 40 y...

journal_title：Annals of neurology

authors： Radhakrishnan K,Mokri B,Parisi JE,O'Fallon WM,Sunku J,Kurland LT

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:We utilized the amyloid imaging ligand Pittsburgh Compound B (PiB) to determine the presence of Alzheimer's disease (AD) pathology in different mild cognitive impairment (MCI) subtypes and to relate increased PiB binding to other markers of early AD and longitudinal outcome. METHODS:Twenty-six patients with ...

journal_title：Annals of neurology

authors： Wolk DA,Price JC,Saxton JA,Snitz BE,James JA,Lopez OL,Aizenstein HJ,Cohen AD,Weissfeld LA,Mathis CA,Klunk WE,De-Kosky ST

更新日期：2009-05-01 00:00:00

abstract：:Endoneurial fluid pressure (EFP) was recorded by an active, servo-null pressure system after a glass micropipette was inserted into rat sciatic nerve undergoing wallerian degeneration. The lesions were produced by crushing the left sciatic nerve of the anesthetized animal at its point of entry into the thigh. Eighty-f...

journal_title：Annals of neurology

authors： Powell HC,Myers RR,Costello ML,Lampert PW

更新日期：1979-06-01 00:00:00

abstract：:We prospectively recruited 10 patients who presented with urinary retention as a neurological deficit that was attributable to lateral medullary infarction. Of these, 9 patients underwent a urodynamic study, which demonstrated detrusor underactivity of the bladder in 7 patients. Urinary retention developed mainly when...

journal_title：Annals of neurology

authors： Cho HJ,Kang TH,Chang JH,Choi YR,Park MG,Choi KD,Sung SM,Park KP,Jung DS

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Low vitamin D status at birth may be associated with risk of adult onset multiple sclerosis, but this link has not been studied directly. We assessed the relation between neonatal vitamin D concentrations, measured in stored blood samples, and risk of multiple sclerosis. METHODS:This was a population-based c...

journal_title：Annals of neurology

authors： Ueda P,Rafatnia F,Bäärnhielm M,Fröbom R,Korzunowicz G,Lönnerbro R,Hedström AK,Eyles D,Olsson T,Alfredsson L

更新日期：2014-09-01 00:00:00

abstract：:Dopa-responsive dystonia (DRD) is one form of childhood-onset idiopathic torsion dystonia. Adult-onset parkinsonism has appeared in several previously unaffected members in families with DRD suggesting that this may be an additional phenotypical expression of the disease. We report a family with DRD in which 2 women a...

journal_title：Annals of neurology

authors： Nygaard TG,Takahashi H,Heiman GA,Snow BJ,Fahn S,Calne DB

更新日期：1992-11-01 00:00:00

abstract：:The serum and cerebrospinal fluid (CSF) of 8 women with ataxia, 6 of whom also had eye movement abnormalities believed to be opsoclonus, were found to contain a highly specific antineuronal antibody we call anti-Ri. Seven of the 8 women also had or developed cancer: carcinoma of the breast in 5, adenocarcinoma in an a...

journal_title：Annals of neurology

authors： Luque FA,Furneaux HM,Ferziger R,Rosenblum MK,Wray SH,Schold SC Jr,Glantz MJ,Jaeckle KA,Biran H,Lesser M

更新日期：1991-03-01 00:00:00

abstract：:In 2006, Yamanaka's group pioneered a method for reprogramming somatic cells by introducing definite transcription factors, which enabled the generation of induced pluripotent stem cells (iPSCs) with pluripotency comparable to that of embryonic stem cells. These iPSCs are attracting considerable attention for their po...

journal_title：Annals of neurology

authors： Ito D,Okano H,Suzuki N

更新日期：2012-08-01 00:00:00

abstract：:Axonal degeneration is a major cause of permanent neurological deficit in multiple sclerosis (MS), but no current therapies for the disease are known to be effective at axonal protection. Here, we examine the ability of a sodium channel-blocking agent, flecainide, to reduce axonal degeneration in an experimental model...

journal_title：Annals of neurology

authors： Bechtold DA,Kapoor R,Smith KJ

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Guillain-Barré syndrome (GBS) is an acute postinfectious immune-mediated polyneuropathy. Although preceding respiratory tract infections with Mycoplasma pneumoniae have been reported in some cases, the role of M. pneumoniae in the pathogenesis of GBS remains unclear. We here cultured, for the first time, M. p...

journal_title：Annals of neurology

authors： Meyer Sauteur PM,Huizinga R,Tio-Gillen AP,Roodbol J,Hoogenboezem T,Jacobs E,van Rijn M,van der Eijk AA,Vink C,de Wit MC,van Rossum AM,Jacobs BC

更新日期：2016-10-01 00:00:00

abstract：:Classic late infantile neuronal ceroid lipofuscinosis (LINCL) is a neurodegenerative disease in which autofluorescent "curvilinear" storage bodies accumulate in tissues from affected patients. Recently, the LINCL gene (CLN2) has been found to code for a pepstatin-insensitive lysosomal protease whose activity is defici...

journal_title：Annals of neurology

authors： Berry-Kravis E,Sleat DE,Sohar I,Meyer P,Donnelly R,Lobel P

更新日期：2000-02-01 00:00:00

abstract：:The present study aimed at determining the distribution and somatotopical organization of striatal activation during performance of simple motor tasks. Ten right-handed healthy volunteers were studied by using a 3-T whole-body magnetic resonance unit and echo planar imaging. The tasks consisted of self-paced flexion/e...

journal_title：Annals of neurology

authors： Lehéricy S,van de Moortele PF,Lobel E,Paradis AL,Vidailhet M,Frouin V,Neveu P,Agid Y,Marsault C,Le Bihan D

更新日期：1998-09-01 00:00:00

abstract：:Nowadays, the "flipped classroom" approach is taking the center stage within medical education. However, very few reports on the implementation of the flipped classroom in neurology have been published to date, and this educational model still represents a challenge for students and educators alike. In this article, n...

journal_title：Annals of neurology

authors： Sandrone S,Berthaud JV,Carlson C,Cios J,Dixit N,Farheen A,Kraker J,Owens JWM,Patino G,Sarva H,Weber D,Schneider LD

更新日期：2020-01-01 00:00:00

abstract：:A 51-year-old diabetic woman developed bilateral rhinoorbitocerebral phycomycosis. Successful treatment was accomplished by correction of the ketoacidosis, surgical debridement, and amphotericin B therapy. Rhinoorbitocerebral phycomycosis is a fulminant and frequently fatal disease most often seen in debilitated hosts...

journal_title：Annals of neurology

authors： Kasper LH,Bernat JL,Nordgren RE,Reeves AG

更新日期：1979-08-01 00:00:00

abstract：:A 64-year-old man developed lethargy and aphasia immediately following cerebral arteriography with iothalamate meglumine. An electroencephalogram showed continuous epileptiform activity. The patient was treated with intravenous phenytoin with complete resolution of clinical symptoms and electroencephalographic epilept...

journal_title：Annals of neurology

authors： Vickrey BG,Bahls FH

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVE:A study was undertaken to describe the clinical spectrum, voltage-gated potassium channel (VGKC) complex antibody specificities, and central nervous system localization of antibody binding in 29 patients diagnosed with Morvan syndrome (MoS). METHODS:Clinical data were collected using questionnaires. Radioimm...

journal_title：Annals of neurology

authors： Irani SR,Pettingill P,Kleopa KA,Schiza N,Waters P,Mazia C,Zuliani L,Watanabe O,Lang B,Buckley C,Vincent A

更新日期：2012-08-01 00:00:00

abstract：:The site of autonomic deficit was investigated in 4 patients with loss of thermoregulatory flushing and sweating on one side of the face but no associated miosis (harlequin syndrome). In 2 patients the sudomotor deficit included the hand. Signs of postganglionic sympathetic deficit included pathological lacrimal sweat...

journal_title：Annals of neurology

authors： Drummond PD,Lance JW

更新日期：1993-12-01 00:00:00

abstract：:Understanding of the organization and function of a newly identified neuronal messenger molecule, nitric oxide, has progressed rapidly. Nitric oxide synthase has been purified and molecularly cloned from brain. Its localization is exclusively neuronal and endothelial. The catalytic activity of nitric oxide synthase ac...

journal_title：Annals of neurology

authors： Dawson TM,Dawson VL,Snyder SH

更新日期：1992-09-01 00:00:00

abstract：:Dentatorubral-pallidoluysian atrophy is an autosomal dominant neurodegenerative disease characterized by various combinations of ataxia, choreoathetosis, myoclonus, epilepsy, and dementia as well as a wide range of ages at onset. A specific unstable trinucleotide repeat expansion in a gene on the short arm of chromoso...

journal_title：Annals of neurology

authors： Ikeuchi T,Koide R,Tanaka H,Onodera O,Igarashi S,Takahashi H,Kondo R,Ishikawa A,Tomoda A,Miike T

更新日期：1995-06-01 00:00:00

abstract：:Multiple sclerosis (MS) has been associated with HLA-DR2 for more than 20 years, and a large number of studies have addressed the relation between MS and the HLA class II genes, which are our major immune-response genes. This has produced a complex and confusing picture that is difficult to interpret. With the advent ...

journal_title：Annals of neurology

authors： Hillert J

更新日期：1994-01-01 00:00:00

abstract：:WAIS performance was compared in 35 pairs of left- and right-handed subjects who had been individually matched for lateralization, cause of brain damage, age, education, and gender. WAIS results were similar in the two groups as well as in two subgroups of subjects with unilateral brain damage. No differences between ...

journal_title：Annals of neurology

authors： Todd J,Satz P

更新日期：1977-11-01 00:00:00

abstract：:We measured neurotransmitter markers in autopsied brain of infants with glycine encephalopathy (GE). Because patients with GE develop intractable seizures, special attention was devoted to those neurotransmitter systems implicated in human epilepsy. Mean levels of glycine in the frontal cortex of GE patients were thre...

journal_title：Annals of neurology

authors： Kish SJ,Dixon LM,Burnham WM,Perry TL,Becker L,Cheng J,Chang LJ,Rebbetoy M

更新日期：1988-09-01 00:00:00

abstract：:Because of the association of D-penicillamine (DP) therapy with myasthenia gravis, we have studied long-term DP treatment in five inbred strains of mice with doses comparable to those used in patients with rheumatoid arthritis. No clinical weakness or anti-acetylcholine receptor (AChR) antibody developed with up to 6 ...

journal_title：Annals of neurology

authors： Bever CT Jr,Dretchen KL,Blake GJ,Chang HW,Penn AS,Asofsky R

更新日期：1984-07-01 00:00:00

abstract：:We report the first molecular defect in an NADH-dehydrogenase gene presenting as isolated myopathy. The proband had lifelong exercise intolerance but no weakness. A muscle biopsy showed cytochrome c oxidase (COX)-positive ragged-red fibers (RRFs), and analysis of the mitochondrial enzymes revealed complex I deficiency...

journal_title：Annals of neurology

authors： Andreu AL,Tanji K,Bruno C,Hadjigeorgiou GM,Sue CM,Jay C,Ohnishi T,Shanske S,Bonilla E,DiMauro S

更新日期：1999-06-01 00:00:00

abstract：:Regular, evidence-based assignment of patients to etiologic stroke categories is essential to enable valid comparison among studies. We designed an algorithm (SSS-TOAST) that incorporated recent advances in stroke imaging and epidemiology to identify the most probable TOAST category in the presence of evidence for mul...

journal_title：Annals of neurology

authors： Ay H,Furie KL,Singhal A,Smith WS,Sorensen AG,Koroshetz WJ

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess the associations of blood biomarkers of carbohydrate, lipid, and apolipoprotein metabolisms with the future risk of amyotrophic lateral sclerosis (ALS). METHODS:In the Apolipoprotein-related MOrtality RISk study, we enrolled 636,132 men and women during 1985-1996 in Stockholm, Sweden, with measurem...

journal_title：Annals of neurology

authors： Mariosa D,Hammar N,Malmström H,Ingre C,Jungner I,Ye W,Fang F,Walldius G

更新日期：2017-05-01 00:00:00

abstract：:Epilepsy is a disease of recurrent seizures that can develop after a wide range of brain insults. Although surgical resection of focal regions of seizure onset can result in clinical improvement, the molecular mechanisms that produce and maintain focal hyperexcitability are not understood. Here, we demonstrate a regio...

journal_title：Annals of neurology

authors： Rakhade SN,Yao B,Ahmed S,Asano E,Beaumont TL,Shah AK,Draghici S,Krauss R,Chugani HT,Sood S,Loeb JA

更新日期：2005-11-01 00:00:00

abstract：:The mechanisms responsible for early prenecrotic ischemic brain edema were investigated in rats by comparing brain metabolism, tissue water (HOH) content, and sodium and potassium ion concentration in brain during ischemia induced by decapitation, by the Pulsinelli-Brierley technique, and by carotid embolization. Alth...

journal_title：Annals of neurology

authors： Kogure K,Busto R,Scheinberg P

更新日期：1981-03-01 00:00:00

abstract：:Thirty patients in whom the initial diagnosis of multiple sclerosis was clinically entertained underwent cranial magnetic resonance imaging (MRI) in close temporal relationship to cranial x-ray computed tomography (CT), electrodiagnostic studies (visual evoked responses, brainstem auditory evoked responses, and somato...

journal_title：Annals of neurology

authors： Gebarski SS,Gabrielsen TO,Gilman S,Knake JE,Latack JT,Aisen AM

更新日期：1985-05-01 00:00:00