Abstract:
:White matter degeneration is one of the pathological conditions of dentatorubral-pallidoluysian atrophy. Autopsy brains exhibited a reduced number of glial cells in the lesions and an involvement of oligodendrocytes in nuclear inclusion formation, which previously has been recognized only as a pathological hallmark in neurons. Dentatorubral-pallidoluysian atrophy transgenic mice showed an increased number of affected glias with increasing age and with larger expansions of CAG repeats. These findings suggest that glial cells in dentatorubral-pallidoluysian atrophy also are involved in the polyglutamine pathogenesis.
journal_name
Ann Neuroljournal_title
Annals of neurologyauthors
Yamada M,Sato T,Tsuji S,Takahashi Hdoi
10.1002/ana.10352keywords:
subject
Has Abstractpub_date
2002-11-01 00:00:00pages
670-4issue
5eissn
0364-5134issn
1531-8249journal_volume
52pub_type
杂志文章abstract::Three patients with inferior branch palsies of the oculomotor nerve are described. Two were under 10 years of age and the third was 30 years old at the onset. All 3 presented with painless diplopia. The onset was sudden in 2 patients and progressive in the third. The palsy cleared within a short time in the 2 patients...
journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410020414
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journal_title:Annals of neurology
pub_type: 杂志文章,随机对照试验
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journal_title:Annals of neurology
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doi:10.1002/ana.21058
更新日期:2007-02-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.21339
更新日期:2008-04-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.410430321
更新日期:1998-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:1999-11-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410280519
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Annals of neurology
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.23689
更新日期:2012-12-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410020413
更新日期:1977-10-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.410210510
更新日期:1987-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.410140611
更新日期:1983-12-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.10357
更新日期:2002-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/ana.410310107
更新日期:1992-01-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.21896
更新日期:2010-02-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.24641
更新日期:2016-06-01 00:00:00
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pub_type: 临床试验,杂志文章
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410330307
更新日期:1993-03-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.21628
更新日期:2009-10-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410370505
更新日期:1995-05-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,meta分析
doi:10.1002/ana.23944
更新日期:2013-10-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.10675
更新日期:2003-09-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.24946
更新日期:2017-06-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410100204
更新日期:1981-08-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410100604
更新日期:1981-12-01 00:00:00