Cognitive control in the posterior frontolateral cortex: evidence from common activations in task coordination, interference control, and working memory.

Abstract:

:Cognitive control has often been associated with activations of middorsolateral prefrontal cortex. However, recent evidence highlights the importance of a more posterior frontolateral region around the junction of the inferior frontal sulcus and the inferior precentral sulcus (the inferior frontal junction area, IFJ). In the present experiment, we investigated the involvement of the IFJ in a task-switching paradigm, a manual Stroop task, and a verbal n-back task in a within-session within-group design. After computing contrasts for the individual tasks, the resulting z maps were overlaid to identify areas commonly activated by these tasks. Common activations were found in the IFJ, in the pre-SMA extending into mesial BA 8, in the middle frontal gyrus bordering the inferior frontal sulcus, in the anterior insula, and in parietal and thalamic regions. These results indicate the existence of a network of prefrontal, parietal, and subcortical regions mediating cognitive control in task coordination, interference control, and working memory. In particular, the results provide evidence for the assumption that, in the frontolateral cortex, not only the middorsolateral region but also the IFJ plays an important role in cognitive control.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Derrfuss J,Brass M,von Cramon DY

doi

10.1016/j.neuroimage.2004.06.007

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

604-12

issue

2

eissn

1053-8119

issn

1095-9572

pii

S1053811904003167

journal_volume

23

pub_type

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