Abstract:
:Diffusion MRI tractography is essential for reconstructing white-matter projections in the living human brain. Yet tractography results miss some projections and falsely identify others. A challenging example is the optic radiation (OR) that connects the thalamus and the primary visual cortex. Here, we tested whether OR tractography can be optimized using quantitative T1 mapping. Based on histology, we proposed that myelin-sensitive T1 values along the OR should remain consistently low compared with adjacent white matter. We found that complementary information from the T1 map allows for increasing the specificity of the reconstructed OR tract by eliminating falsely identified projections. This T1-filtering outperforms other, diffusion-based tractography filters. These results provide evidence that the smooth microstructural signature along the tract can be used as constructive input for tractography. Finally, we demonstrate that this approach can be applied in a case of multiple sclerosis, and generalized to the HCP-available MRI measurements. We conclude that multimodal MRI microstructural information can be used to eliminate spurious tractography results in the case of the OR.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Schurr R,Duan Y,Norcia AM,Ogawa S,Yeatman JD,Mezer AAdoi
10.1016/j.neuroimage.2018.06.060subject
Has Abstractpub_date
2018-11-01 00:00:00pages
645-658eissn
1053-8119issn
1095-9572pii
S1053-8119(18)30567-6journal_volume
181pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::The way humans comprehend narrative speech plays an important part in human development and experience. A group of 313 children with ages 5-18 were subjected to a large-scale functional magnetic resonance imaging (fMRI) study in order to investigate the neural correlates of auditory narrative comprehension. The result...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.08.028
更新日期:2007-01-01 00:00:00
abstract::For many years now, Magnetic Resonance Innovations (MR Innovations), a magnetic resonance imaging (MRI) software development, technology, and research company, has been aggregating a multitude of MRI data from different scanning sites through its collaborations and research contracts. The majority of the data has adhe...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.04.066
更新日期:2016-01-01 00:00:00
abstract::Head motion causes artifacts in functional magnetic resonance imaging (fMRI) scans, a problem especially relevant for task-free resting state paradigms and for developmental, aging, and clinical populations. In a cohort spanning 7-28 years old (mean age 15) we produced customized head-anatomy-specific Styrofoam molds ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.01.016
更新日期:2019-04-01 00:00:00
abstract::The human ventral visual stream consists of several areas that are considered processing stages essential for perception and recognition. A fundamental microanatomical feature differentiating areas is cytoarchitecture, which refers to the distribution, size, and density of cells across cortical layers. Because cytoarc...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.02.040
更新日期:2018-04-15 00:00:00
abstract::Neighboring contextual elements can dramatically affect the manner in which the brain processes the perceptual characteristics of an object. Indeed, many well-known visual illusions rely on misleading contextual cues to create misperceptions of size, length or orientation (e.g., in the Ebbinghaus, Muller-Lyer or rod-a...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.06.016
更新日期:2008-10-01 00:00:00
abstract::We report the deployment of spiral acquisition for high-resolution structural imaging at 7T. Long spiral readouts are rendered manageable by an expanded signal model including static off-resonance and B0 dynamics along with k-space trajectories and coil sensitivity maps. Image reconstruction is accomplished by inversi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.07.062
更新日期:2018-03-01 00:00:00
abstract::Large amounts of multimodal neuroimaging data are acquired every year worldwide. In order to extract high-dimensional information for computational neuroscience applications standardized data fusion and efficient reduction into integrative data structures are required. Such self-consistent multimodal data sets can be ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.03.055
更新日期:2015-08-15 00:00:00
abstract::Accurate characterization of the spatiotemporal relationship between two of the most prominent neuroimaging measures of neuronal activity, the 8-13Hz, occipito-parietal EEG alpha oscillation and the BOLD fMRI signal, must encompass the intrinsically dynamic nature of both alpha power and brain function. Here, during t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.04.051
更新日期:2017-07-15 00:00:00
abstract::The primary visual cortex of humans contains patches of neurons responding preferentially to stimulation of one eye (the ocular dominance columns). Multiple previous studies attempted to detect their activity using fMRI. The majority of these fMRI studies used magnetic field strengths of 4 T and higher. However, ther...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117078
更新日期:2020-10-15 00:00:00
abstract::Sensorimotor synchronization (SMS) to an external auditory rhythm is a developed ability in humans, particularly evident in dancing and singing. This ability is typically measured in the lab via a simple task of finger tapping to an auditory beat. While simplistic, there is some evidence that poor performance on this ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.05.022
更新日期:2016-09-01 00:00:00
abstract::With information constantly bombarding the human sensory systems, how is it that we attend to behaviorally relevant information? The present study examined the behavioral and neural bases of attending to one sense while ignoring another sense (bimodal selective attention) contrasted with attending simultaneously to tw...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2006.02.026
更新日期:2006-07-15 00:00:00
abstract::To investigate cortical auditory and motor coupling in professional musicians, we compared the functional magnetic resonance imaging (fMRI) activity of seven pianists to seven non-musicians utilizing a passive task paradigm established in a previous learning study. The tasks involved either passively listening to shor...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2005.10.044
更新日期:2006-04-15 00:00:00
abstract::Current neurobiological models assign a central role to predictive processes calibrated to environmental statistics. Neuroimaging studies examining the encoding of stimulus uncertainty have relied almost exclusively on manipulations in which stimuli were presented in a single sensory modality, and further assumed that...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.02.019
更新日期:2018-06-01 00:00:00
abstract::Fine-grained functional organization of cortex is not well-conserved across individuals. As a result, individual differences in cortical functional architecture are confounded by topographic idiosyncrasies-i.e., differences in functional-anatomical correspondence. In this study, we used hyperalignment to align informa...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.08.029
更新日期:2018-12-01 00:00:00
abstract::Feedback error-related negativity (fERN) has been referred to as a negative deflection in the event related potential (ERP), which distinguishes between wins and losses in terms of expected and unexpected outcomes. Some studies refer to the "expected outcome" as the probability to win vs. to lose, and others as expect...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.03.031
更新日期:2010-07-01 00:00:00
abstract::Functional Magnetic Resonance Imaging (fMRI) shows significant potential as a tool for predicting clinically important information such as future disease progression or drug effect from brain activity. Multivariate techniques have been developed that combine fMRI signals from across the brain to produce more robust pr...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.12.053
更新日期:2012-03-01 00:00:00
abstract::This work describes a reproducibility analysis of scalar water diffusion parameters, measured within white matter tracts segmented using a probabilistic shape modelling method. In common with previously reported neighbourhood tractography (NT) work, the technique optimises seed point placement for fibre tracking by ma...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.12.010
更新日期:2009-04-01 00:00:00
abstract::In infants, the fontanels and sutures as well as conductivity of the skull influence the volume currents accompanying primary currents generated by active neurons and thus the associated electroencephalography (EEG) and magnetoencephalography (MEG) signals. We used a finite element method (FEM) to construct a realisti...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.03.017
更新日期:2013-08-01 00:00:00
abstract::Time perception is compromised in emotional situations, yet our ability to remember these events is enhanced. Here we suggest how the two phenomena might be functionally linked and describe the neural networks that underlie this association. We found that participants perceived an emotionally aversive stimulus longer ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.06.041
更新日期:2012-10-15 00:00:00
abstract::MRI at 3 T has increased sensitivity in detecting overt multiple sclerosis (MS) brain lesions; a growing body of data suggests clinically relevant damage occurs in the normal-appearing white matter (NAWM). We tested a novel pulse sequence to determine whether 3 T MRI spin-spin relaxometry detected damage in NAWM of MS...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.03.001
更新日期:2009-07-01 00:00:00
abstract::Fine-grained activity patterns, as measured with functional magnetic resonance imaging (fMRI), are thought to reflect underlying neural representations. Multivariate analysis techniques, such as representational similarity analysis (RSA), can be used to test models of brain representation by quantifying the representa...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.11.002
更新日期:2019-02-01 00:00:00
abstract::The BOLD signal, as the basis of functional MRI, arises from both neuronal and vascular factors, with their respective contributions to resting state-fMRI still unknown. Among the factors contributing to "physiological noise", dynamic arterial CO2 fluctuations constitutes the strongest and the most widespread modulato...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116874
更新日期:2020-08-01 00:00:00
abstract::Our visual system readily groups dynamic fragmented input into global objects. How the brain represents global object perception remains however unclear. To address this question, we recorded brain responses using functional magnetic resonance imaging whilst observers viewed a dynamic bistable stimulus that could eith...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116926
更新日期:2020-10-15 00:00:00
abstract::The gamma-band response is thought to represent a key neural signature of information processing in the human brain. These brain signals have been associated with a variety of sensory modalities (vision, sensation, and audition) and also following basic motor responses, yet the functional significance of the motor gam...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.02.013
更新日期:2013-07-01 00:00:00
abstract::Contradictory reports regarding the detection of neuronal currents have left the feasibility of neuronal current MRI (ncMRI) an open question. Most previous ncMRI studies in human subjects are suspect due to their inability to separate or eliminate hemodynamic effects. In this study, we used a bloodless turtle brain p...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.06.017
更新日期:2009-10-01 00:00:00
abstract::BOLD fMRI localizes activated brain areas by measuring decreases of deoxygenated hemoglobin (deoxy-Hb) caused by neurovascular coupling. To date, it is unclear whether intracranial pressure (ICP) modifies deoxy-Hb signaling for brain mapping. In addition, ICP elevation can test whether the BOLD post-stimulus undershoo...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.04.237
更新日期:2010-08-15 00:00:00
abstract::In February of 2012, the first international conference on real time functional magnetic resonance imaging (rtfMRI) neurofeedback was held at the Swiss Federal Institute of Technology Zurich (ETHZ), Switzerland. This review summarizes progress in the field, introduces current debates, elucidates open questions, and of...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2013.03.033
更新日期:2013-08-01 00:00:00
abstract::The veins of the dentate nucleus are composed of several channels draining the external surface and one single vein draining the internal surface. We analyzed specimens of the human cerebellum and described the central vein of the nucleus dentatus as the main venous outflow of the nucleus. The central vein of the nucl...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.07.045
更新日期:2011-01-01 00:00:00
abstract::Scientists who study cognition infer underlying processes either by observing behavior (e.g., response times, percentage correct) or by observing neural activity (e.g., the BOLD response). These two types of observations have traditionally supported two separate lines of study. The first is led by cognitive modelers, ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.01.048
更新日期:2013-05-15 00:00:00
abstract::Models of action selection postulate the critical involvement of the subthalamic nucleus (STN), especially in reactive inhibition processes when inappropriate responses to a sudden stimulus must be overridden. The STN could also play a key role during proactive inhibition, when subjects prepare to potentially suppress...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.10.070
更新日期:2014-05-01 00:00:00