Abstract：
:Chronic exposure to organic contaminants such as polychlorinated biphenyls (PCBs) can lead to the development of resistance to these chemicals, a condition associated with reduced response of CYP1A1, a pollutant-inducible biomarker. We measured CYP1A activity (ethoxyresorufin o-deethylase, EROD) and PCB concentrations in feral fish from the Town Branch/Mud River system (Logan County, KY), a stream historically contaminated with PCBs and partially remediated. As a first step in evaluating the possible development of resistant populations in this system, we measured CYP1A expression and PCB body burdens in resident fish from sites we previously characterized as containing biologically significant levels of CYP1A inducing compounds. Mean PCB concentrations in edible flesh ranged from 75.2 to 16.7 microg/g in fish collected from Town Branch remediated sites and were relatively low (1.23 microg/g) in Town Branch reference site fish. However, hepatic CYP1A activity was similar among individuals of most species collected from reference and contaminated/remediated sites. The absence of elevated CYP1A levels in resident fish species despite the presence of significant PCB body burdens may indicate these fish have developed reduced sensitivity to CYP1A induction, a condition associated with acquired resistance to toxicants.
journal_name
Mar Environ Resjournal_title
Marine environmental researchauthors
Brammell BF,Price DJ,Birge WJ,Elskus AAdoi
10.1016/j.marenvres.2004.03.067keywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
251-5issue
2-5eissn
0141-1136issn
1879-0291pii
S0141-1136(04)00054-6journal_volume
58pub_type
杂志文章abstract：:We investigated the long-term effects of contaminants in sediment from Baltimore Harbor, MD, USA, on a burrowing amphipod (Leptocheirus plumulosus) via a full life-cycle laboratory exposure. Contaminants in the Baltimore Harbor sediment included PAHs (10,800 ng/g), PCBs (152 ng/g), and heavy metals (including As, Cd, ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2006.03.006
更新日期：2006-08-01 00:00:00
abstract：:Reef-building species play key roles in promoting local species richness and regulating ecosystem functions like biogeochemical fluxes. We evaluated the functioning of a habitat engineered by the reef-building polychaete Sabellaria alveolata, by measuring oxygen and nutrient fluxes in the reef structures and in the so...
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pub_type： 杂志文章
doi：10.1016/j.marenvres.2018.10.003
更新日期：2018-11-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.10.011
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journal_title：Marine environmental research
pub_type： 杂志文章
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journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-06-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2001-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.02.057
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.12.001
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.10.006
更新日期：2009-02-01 00:00:00
abstract：:The role of seawater NOM in reducing metal toxicity for marine organisms is not well understood. We investigated the effects of five different marine NOMs (two autochthonous, one allochthonous, two of mixed origin, at 8 mg C/L), three metals (6 μg Cu/L; 20 μg Pb/L; 25 μg Zn/L), and combinations between them, to early ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.12.009
更新日期：2018-04-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2013.03.006
更新日期：2013-06-01 00:00:00
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journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.09.011
更新日期：2012-05-01 00:00:00
abstract：:Previous studies have shown that metal partitioned to a subcellular compartment containing trophically available metal (TAM) is readily available to predators and may be enhanced by increased binding of metal to heat-stable proteins (HSP - e.g., metallothioneins). The aim of the current investigation was to determine ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2004.07.003
更新日期：2005-06-01 00:00:00
abstract：:Some subtidal habitats may experience extremely large diel temperature fluctuations. To explore the potential of subtidal animals to regulate their metabolic processes, we investigated how the oxygen consumption rate (MO2) of the sea urchin Mesocentrotus nudus changes in response to extreme temperature fluctuations by...
journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2019-02-01 00:00:00
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pub_type： 杂志文章
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abstract：:Extensive research has shown that the early life stages of marine organisms are sensitive to ocean acidification (OA). Less is known, however, on whether larval settlement and metamorphosis may be affected, or by which mechanisms. These are key processes in the life cycle of most marine benthic organisms, since they m...
journal_title：Marine environmental research
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journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2015-05-01 00:00:00
abstract：:Glutathione S-transferase (GST) and heat shock proteins (hsps) 40, 60, 70 and 90 were determined by immunoblotting using actin as an internal control in Mytilus edulis from one station outside (site1) and three stations within (sites 2-4) Cork Harbour, Ireland. Comparisons were made between gill and digestive gland an...
journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2003-12-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants of the marine environment, arising predominantly from petrochemical contamination and pyrogenic sources. A biomarker of PAH exposure was employed in a field study (South West, Spain) in both captured (indigenous) and deployed (caged) shore crabs (Carcin...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2010.03.003
更新日期：2010-07-01 00:00:00
abstract：:Environmental changes have been associated with natural climatic variability or human activity. Water resources management is, perhaps, the most drastic change observed in the coastal environment. However, external forcings such as the El Niño event have important implications in the global and regional hydrological b...
journal_title：Marine environmental research
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
abstract：:Understanding the movements of fish in relation to areas of contaminated and urbanized habitats is crucial to fisheries management and habitat remediation. In this study, the movements of white croaker in the Los Angeles and Long Beach Harbors were examined using both active and passive acoustic telemetry tracking. Da...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2016.08.004
更新日期：2016-09-01 00:00:00
abstract：:Adopting an integrated approach the potential genotoxic, cytotoxic and developmental effects of tributyltin oxide (TBTO), a known endocrine-disrupting agent for neogastropods, have been evaluated in two ecologically relevant invertebrates: Mytilus edulis (blue mussel) and Platynereis dumerilli (rag worm). Following de...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00112-4
更新日期：2000-07-01 00:00:00
abstract：:The Mondego estuary (Portugal) went through different ecological scenarios over the last decades. An eutrophication process led to a decline in the ecosystem quality. The ensuing restoration plan resulted into a gradual ecological recovery, which was impaired by the occurrence of successive extreme climate events that...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2014.03.004
更新日期：2014-07-01 00:00:00
abstract：:In this study we examined the effect of: observer presence; observer speed; and the impact that multiple surveys had on the number of counted fish in a visual census survey in a typical Mediterranean rocky habitat. SCUBA observer presence had no influence on the number of fish per survey. An improvement in the methodo...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00028-3
更新日期：2001-02-01 00:00:00
abstract：:Concentrations of cadmium, copper, iron, lead, manganese, nickel and zinc were investigated in two species of mussel from the Kuril Islands in the north-western Pacific Ocean: the short-lived mussel Mytilus trossulus and the much larger and longer-lived Crenomytilus grayanus. The concentrations of most elements were l...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00264-6
更新日期：2002-04-01 00:00:00
abstract：:We have shown previously that exposure of Atlantic croaker to a PCB mixture (Aroclor 1254) results in impaired reproductive neuroendocrine function. In addition, we have identified hypothalamic tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin (5-hydroxytryptamine) synthesis, as a target of PCB neuro...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2004.03.077
更新日期：2004-08-01 00:00:00
