Abstract：
:Adopting an integrated approach the potential genotoxic, cytotoxic and developmental effects of tributyltin oxide (TBTO), a known endocrine-disrupting agent for neogastropods, have been evaluated in two ecologically relevant invertebrates: Mytilus edulis (blue mussel) and Platynereis dumerilli (rag worm). Following determination of the maximum tolerated dose (MTD) in terms of developmental and survival effects, the embryo-larval stages of these organisms were exposed to a range of concentrations of TBTO, and analysed for cytotoxic (proliferation rate index) and genotoxic (sister chromatid exchanges and chromosomal aberrations) effects. The study suggested that: (1) TBTO is both toxic and genotoxic to embryo-larval stages of both species; (2) at comparable concentrations, for developmental and genotoxic effects, P. dumerilii (non-target species) is more sensitive compared to M. edulis (target species); and (3) genotoxic effects are more closely tied with the development and survival of the organisms. The study emphasises the need of the evaluation of genotoxic potential of other endocrine-disrupting agents in different taxonomic groups.
journal_name
Mar Environ Resjournal_title
Marine environmental researchauthors
Jha AN,Hagger JA,Hill SJ,Depledge MHdoi
10.1016/s0141-1136(00)00112-4keywords:
subject
Has Abstractpub_date
2000-07-01 00:00:00pages
565-73issue
1-5eissn
0141-1136issn
1879-0291pii
S0141-1136(00)00112-4journal_volume
50pub_type
杂志文章abstract：:The aim of this work is to review studies to evaluate how emissions from fish cage farms cause eutrophication effects in marine environments. The focus is on four different scales: (i) the conditions at the site of the farm, (ii) the local scale related to the coastal area where the farm is situated, (iii) the regiona...
journal_title：Marine environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.marenvres.2004.10.005
更新日期：2005-08-01 00:00:00
abstract：:This study assesses the relative importance of water and sediments as vectors of TBT uptake in the sediment-dwelling suspension feeder, Ruditapes decussatus. Accumulation of TBT was determined in R. decussatus exposed for 60 days to moderately high but environmentally realistic levels of TBT in water (100 ng Snl(-1)) ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00104-6
更新日期：2002-08-01 00:00:00
abstract：:Plankton samples (20-350 microm and >350 microm) collected at three transects along the Galician coast (NW Spain) were analysed for individual aliphatic and aromatic hydrocarbons by GC-MS. Sample collection was performed in April-July 2003, after the Prestige oil spill (November 2002), to determine whether the hydroca...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2006.06.004
更新日期：2006-12-01 00:00:00
abstract：:Plasma vitellogenin and related parameters in the killifish Fundulus heteroclitus were measured at selected sites in the Chesapeake Bay. In males, vitellogenin was above the detection limit 14% of the time, and detections did not differ between sites or seasons. Few differences in plasma vitellogenin levels were found...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2009.06.006
更新日期：2009-10-01 00:00:00
abstract：:Concern over endocrine disrupters in coastal ecosystems has stimulated global efforts to understand their potential impacts on fish and invertebrate communities. Given that marine crustaceans are sensitive to the effects of alkylphenols and other xenobiotics, we are currently investigating whether these responses may ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00113-7
更新日期：2002-09-01 00:00:00
abstract：:Seagrasses represent high primary productivity and provide important ecosystem services to the marine environment. Seagrass-associated microbial communities are playing essential ecological functional roles in biogeochemical cycles. However, little is known about the effect of seagrass vegetation on microbial communit...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105174
更新日期：2020-12-01 00:00:00
abstract：:Concentrations of cadmium, copper, iron, lead, manganese, nickel and zinc were investigated in two species of mussel from the Kuril Islands in the north-western Pacific Ocean: the short-lived mussel Mytilus trossulus and the much larger and longer-lived Crenomytilus grayanus. The concentrations of most elements were l...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00264-6
更新日期：2002-04-01 00:00:00
abstract：:The aim of this investigation was to test the hypothesis that fasting-induced augmented lysosomal autophagic turnover of cellular proteins and organelles will reduce potentially harmful lipofuscin (age-pigment) formation in cells by more effectively removing oxidatively damaged proteins. An animal model (marine snail-...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2015.04.001
更新日期：2015-06-01 00:00:00
abstract：:Understanding the movements of fish in relation to areas of contaminated and urbanized habitats is crucial to fisheries management and habitat remediation. In this study, the movements of white croaker in the Los Angeles and Long Beach Harbors were examined using both active and passive acoustic telemetry tracking. Da...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2016.08.004
更新日期：2016-09-01 00:00:00
abstract：:The Quality of Rocky Bottoms index (CFR by its Spanish acronym) is a multimetric method used for the assessment of macroalgae communities in accordance to the European Water Framework Directive. In order to improve the precision and accuracy of the assessments, the index was adjusted using a continuous scoring system....
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2014.06.002
更新日期：2014-12-01 00:00:00
abstract：:The Ria Formosa lagoon is an ecosystem whose water quality reflects the anthropogenic influence upon the surrounding areas. In this lagoon, the clam Ruditapes decussatus has a great economical importance and has been widely used as a biomonitor. A multibiomarker approach (δ-aminolevulinic acid dehydratase, metallothio...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.09.012
更新日期：2012-04-01 00:00:00
abstract：:Rapid and cost-effective methods to monitor the presence of diarrhetic shellfish poisoning (DSP) toxins in seawater samples in an easy and reliable manner are required to protect human health and avoid economic losses to shellfish industry. Immunoassays for the detection of okadaic acid (OA) and dinophysistoxin-1 and ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.11.004
更新日期：2018-02-01 00:00:00
abstract：:Extensive research has shown that the early life stages of marine organisms are sensitive to ocean acidification (OA). Less is known, however, on whether larval settlement and metamorphosis may be affected, or by which mechanisms. These are key processes in the life cycle of most marine benthic organisms, since they m...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.104977
更新日期：2020-07-01 00:00:00
abstract：:Runoff and sewage discharge from land developments can cause significant changes in water quality of coastal waters, resulting in coral degradation. Coastal waters around Phuket, Thailand are influenced by numerous sewage outfalls associated with rapid tourism development. Water quality and biological monitoring aroun...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2009.11.011
更新日期：2010-06-01 00:00:00
abstract：:The number of man-made structures to be placed in the marine environment is set to increase massively in the near future as a consequence of the wide-scale adoption and commercialisation of offshore electricity generation. Marine renewable energy devices (MREDs) interact with their receiving environment and are de-fac...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2014.01.011
更新日期：2014-06-01 00:00:00
abstract：:To better understand the complexity of the brain-pituitary-gonad axis (BPG) in fish, we developed a biologically based pharmacodynamic model capable of accurately predicting the normal functioning of the BPG axis in salmon. This first-generation model consisted of a set of 13 equations whose formulation was guided by ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2006.04.022
更新日期：2006-07-01 00:00:00
abstract：:Natural storms are able to determine reworking of seabed up to considerable depths and favour suspension of sediment-associated chemicals. Yet, a direct link between exposure to resuspended contaminants and the biological effects on marine organisms have to be fully established. We exposed adults of a suspension feede...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.104950
更新日期：2020-06-01 00:00:00
abstract：:Marine pollution due to disused industrial activities is a major threat to ecosystems and human health, for example through the effects of re-suspension of toxic substances that are present in contaminated sediments. Here, we examined the effects of different re-suspension patterns of polluted sediments from the site ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.104978
更新日期：2020-09-01 00:00:00
abstract：:Ocean acidification (OA) is predicted to affect the physiology of some fishes. To date, most studies have investigated this issue using stable pCO2 levels based on open ocean projections. Yet, most shallow, nearshore systems experience temporal and spatial pCO2 fluctuations. For example, pCO2 on coral reefs is highest...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105224
更新日期：2021-01-01 00:00:00
abstract：:In aquatic organisms inhabiting polluted waters genes are activated to build an adaptive/compensatory defence against the possible effects of pollutants. Such responses can be used as biomarkers of exposure to chemical compounds, outlining the molecular mechanisms activated under specific pollution scenarios. With the...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2018.06.009
更新日期：2018-09-01 00:00:00
abstract：:Maritime traffic is one of many anthropogenic pressures threatening the marine environment. This study was specifically designed to investigate the relationship between vessels presence and cetacean sightings in the high sea areas of the Western Mediterranean Sea region. We recorded and compared the total number of ve...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2015.05.009
更新日期：2015-08-01 00:00:00
abstract：:The presence and the development of imposex were investigated in the common whelk (Buccinum undatum) and the red whelk (Neptunea antiqua) from the open North Sea and the Skagerrak. Imposex development was related to levels of organotins in snails and in the fine fractions (< 63 microm) of the sediments they inhabit. T...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00217-9
更新日期：2003-04-01 00:00:00
abstract：:The methods of proteomics, the study of the protein complement of the genome, are applicable to environmental testing. Sets of proteins specific to different stressors can be isolated using computer imaging software. Individual proteins can be identified by mass spectrometry. The Protein Expression Signatures (PES) ob...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00115-0
更新日期：2002-09-01 00:00:00
abstract：:Certain environmentally persistent compounds can adversely affect reproduction by acting as steroid hormone agonists or antagonists. The goal of the present study was to determine the developmental stage most susceptible to exogenous hormone (estradiol and testosterone) exposure using a small teleost model. In the fir...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00068-4
更新日期：2000-07-01 00:00:00
abstract：:The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L(-1)) are presented. Using a 1.7 K feature cDNA microarray along with linear models and empirical Bayes statistical methods 225 differentially exp...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2016.05.010
更新日期：2016-08-01 00:00:00
abstract：:The need to develop powerful tools to detect exposure and effects of POPs and emerging contaminants in Mediterranean cetaceans led us to develop a suite of sensitive non-lethal biomarkers in integument biopsies of free-ranging animals. In order to propose induction of CYP1A1 and CYP2B, detected by Western blot analysi...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.02.006
更新日期：2008-07-01 00:00:00
abstract：:Toxicity tests were performed exposing the polychaete Dinophilus gyrociliatus to seawater samples containing the toxic dinoflagellate Ostreopsis cf. ovata. Experiments were carried out twice in mid summer, when O. cf. ovata bloomed, and twice in late summer, when the dinoflagellate density declined. Each time, four tr...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.08.009
更新日期：2011-10-01 00:00:00
abstract：:Few in vivo studies have been conducted to assess how nanoparticle (NP) characteristics such as particle form and shape affect their toxicity and bioaccumulation. In the present study, the deposit feeder, Capitella teleta, was used to investigate the influence of copper form (CuO NPs, micron-sized CuO particles, and a...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2015.06.010
更新日期：2015-10-01 00:00:00
abstract：:Seasonal shell growth patterns were analyzed using the stable oxygen and carbon isotope values of live-collected specimens of the bivalve Callista chione from two sites in the Adriatic Sea (Pag and Cetina, Croatia). Micromilling was performed on the shell surface of three shells per site and shell oxygen isotopes of t...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2018.01.011
更新日期：2018-03-01 00:00:00
abstract：:Subsea pipelines have been installed in all major hydrocarbon basins across the globe to support the offshore Oil & Gas (O&G) industry. These artificial structures provide hard substratum that can be colonised and utilised by sessile and mobile organisms. The present study utilises industry-collected remotely operated...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2019.104813
更新日期：2019-10-10 00:00:00
