Abstract：
OBJECTIVES:The objective of this study was to explore suitable spatial filters for inverse estimation of cortical potentials from the scalp electroencephalogram. The effect of incorporating noise covariance into inverse procedures was examined by computer simulations and tested in human experiment. METHODS:The parametric projection filter, which allows inverse estimation with the presence of information on the noise, was applied to an inhomogeneous three-concentric-sphere model under various noise conditions in order to estimate the cortical potentials from the scalp potentials. The method for determining the optimum regularization parameter, which can be applied for parametric inverse techniques, is also discussed. RESULTS:Human visual evoked potential experiment was carried out to examine the performance of the proposed restoration method. The parametric projection filter gave more localized inverse solution of cortical potential distribution than the truncated SVD and Tikhonov regularization. CONCLUSION:The present simulation results suggest that incorporation of information on the noise covariance allows better estimation of cortical potentials, than inverse solutions without knowledge about the noise covariance, when the correlation between the signal and noise is low.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Hori J,Lian J,He Bkeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
66-9issue
1eissn
0026-1270issn
2511-705Xpii
04010066journal_volume
43pub_type
杂志文章abstract：:In this study, we attempted to discriminate the acceleration signal for horizontal level and stairway walking using wavelet-based fractal analysis method. The acceleration signal was measured close to the center of gravity of the body, while the subjects walked continuously in the corridor and up and down the stairs. ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:A huge amount of medical information is available on the Internet for both experts and laypersons. These resources are frequently used to answer current medical questions and are thus likely to influence the behavior of the users. Criteria for assessing the quality of medical Internet resources have been established b...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVES:We discuss supervised classification techniques applied to medical diagnosis based on gene expression profiles. Our focus lies on strategies of adaptive model selection to avoid overfitting in high-dimensional spaces. METHODS:We introduce likelihood-based methods, classification trees, support vector machin...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:A Bayesian decision support system was developed for the diagnosis of rheumatic disorders. Knowledge in this system is represented as evidential weights of findings. Simple weights were calculated as the logarithm of likelihood ratios on the basis of 1,000 consecutive patients from a rheumatological clinic. The effect...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVES:The interpretation of endoscopic findings by gastroenterologists is still a difficult and highly subjective task. Despite important developments such as chromo-endoscopy, pit pattern analysis, fluorescence imaging as well as narrow band imaging it still requires lots of experience and training with a certain...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9230
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Each year, the International Medical Informatics Association Yearbook recognizes significant scientific papers, labelled as "best papers", published the previous year in the subfields of biomedical informatics that correspond to the different section topics of the journal. For each section, about fifteen pre...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0031
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:In this study, we evaluated the internal validity of EPICON, an application for grouping ICPC-coded diagnoses from electronic medical records into episodes of care. These episodes are used to estimate morbidity rates in general practice. METHODS:Morbidity rates based on EPICON were compared to a gold standa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:We conducted a pilot randomised trial of computerised templates for the management of asthma and diabetes in general practice in six general practices in North London. Uptake of the guidelines by general practitioners and practice nurses was assessed using qualitative (semi-structured interviews designed to assess the...
journal_title：Methods of information in medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-09-01 00:00:00
abstract：OBJECTIVES:(1) Creation of an expressive language for specification of temporal patterns in clinical domains, (2) Development of a graphical knowledge-acquisition tool allowing expert physicians to define meaningful domain-specific patterns, (3) Implementation of an interpreter capable of detecting such patterns in cli...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Acute appendicitis is the most common cause of acute abdomen requiring surgical intervention. The clinical diagnosis of acute appendicitis is not always easy due to variable symptomatology, particularly at the onset. The contributions of history-taking and physical examination in the diagnosis of acute appendicitis wa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:Requirements and approaches of Software Engineering education in the field of Medical Informatics are described with respect to the impact of (1) experiences characterizing the "software misery", (2) status and tendencies in software methodology, and (3) educational status and needs in computer science education influ...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVES:The International Medical Informatics Association (IMIA) today is an inclusive organization that represents the medical and health informatics world through its multiple member countries as well as affiliate, corporate and academic institutions, plus working groups and regions. The IMIA leadership deemed thi...
journal_title：Methods of information in medicine
pub_type： 社论
doi：
更新日期：2006-01-01 00:00:00
abstract：:Often in drug trials only the objective, or the subjective responses of the subjects are investigated, depending on the kind of drug. It is, however, desirable to check both the objective and the subjective responses in every drug trial. The investigation of the objective symptoms which is especially necessary in psyc...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1963-01-01 00:00:00
abstract：OBJECTIVES:Electroencephalographic burst activity characteristic of burst-suppression pattern (BSP) in sedated patients and of burst-interburst pattern (BIP) in the quiet sleep of healthy neonates have similar linear and non-linear signal properties. Strong interrelations between a slow frequency component and rhythmic...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:Both open- and closed-loop models of beat-to-beat cardiovascular control have been suggested. We tested whether the modelling yields different results with real data while assessing cardiopulmonary and baroreflex gains. METHODS:Two autoregressive models are described to resolve causal relationships between ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:In this work, a cellular automaton software package for simulating different infectious diseases, storing the simulation results in a data warehouse system and analyzing the obtained results to generate prediction models as well as contingency plans, is proposed. The Brisbane H3N2 flu virus, which has been s...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-02-0025
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:The European GEMSS Project is concerned with the creation of medical Grid service prototypes and their evaluation in a secure service-oriented infrastructure for distributed on demand/supercomputing. Key aspects of the GEMSS Grid middleware include negotiable QoS support for time-critical service provision, ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:To find discriminative combination of influential factors of Intracerebral hematoma (ICH) to cluster ICH patients with similar features to explore relationship among influential factors and 30-day mortality of ICH. METHODS:The data of ICH patients are collected. We use a decision tree to find discriminative...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME15-01-0137
更新日期：2016-10-17 00:00:00
abstract：:Medical care and medical education can be supported more than in the past by using new tools and new premises for the effective linkage between bodies of knowledge and the use of that knowledge. The medical record can be converted from a source-oriented record to a problem-oriented record, enabling to trace not only w...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVES:The authors' aim was to investigate the representations, wishes, and fears of family caregivers (FCs) regarding 14 innovative technologies (IT) for care aiding and burden alleviation, given the severe physical and psychological stress induced by dementia care, and the very slow uptake of these technologies i...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:With rapid change in health care requiring greater emphasis on productivity and quality management, occupational health hazards in hospitals have been receiving increasing recognition, now not only focusing on controlling infection, but also on chemical, physical, mechanical as well as psychosocial hazards. Reducing c...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:Lifestyle has a major influence on the development and progression of atherosclerosis. Our motto for healthy habits is "give up one, reduce two, and increase three". The one thing that is to be given up is smoking. The two things that are to be reduced are intake of food and alcohol. The three things that ar...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". OBJECTIVES:In previous work, we have defined methods for the extraction of lexical patterns from labels as an initial step towards semi-automatic ontology enrichme...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-02-0026
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:The main objective of this study is to learn more on the image use and search requirements of radiologists. These requirements will then be taken into account to develop a new search system for images and associated meta data search in the Khresmoi project. METHODS:Observations of the radiology workflow, ca...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME11-02-0025
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:This study aims to demonstrate the usability of discourse analyses as a means of evaluating medical informatics systems by examining one particular computer-based data-to-text system for delivering neonatal health care information. METHODS:Six textual summaries of clinical information, three produced by hum...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0613
更新日期：2010-01-01 00:00:00
abstract：:For use in system development, a method based on both qualitative and quantitative data was employed to study the difficulties--the dilemmas--a general practitioner (GP) faces during daily consultations. Video recordings were used for stimulated recall of the consultation. From 46 consultations, 262 dilemmas were iden...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVES:To assess the effects of a CPOE system on inter-professional workflow in the medication process. METHODS:Twenty-three semi-structured interviews with physicians, nurses, and pharmacists were conducted in a Dutch academic hospital. In addition, the handwritten and system-generated documents used daily were c...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0631
更新日期：2010-01-01 00:00:00
abstract：:A few years ago, a new method of survival analysis, denoted period analysis, has been developed to derive more up-to-date estimates of long-term survival rates of cancer patients, but this method has rarely been applied so far. Using empirical examples from the Saarland Cancer Registry, we illustrate how seriously tra...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:To intensify the collaboration between WHO, the World Health Organization, and IMIA, the International Medical Informatics Association. METHODS:Identifying key areas of collaboration and publishing a joint communiqué during Medinfo 2007 in Brisbane, Australia. RESULTS AND CONCLUSIONS:WHO and IMIA have ident...
journal_title：Methods of information in medicine
pub_type： 社论
doi：10.1160/me5006
更新日期：2007-01-01 00:00:00
abstract：:A new method is presented, different from usual methods, for the discussion of the results of computer ECG measurement programs, based on a new graphical evaluation method. The proposed "scatter-graphs" both highlight the main program results and facilitate the comparison between various wave-recognition algorithms. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
