Abstract:
BACKGROUND:Financial conflict of interest in clinical research is an area of active debate. While data exist on the perspectives and roles of academic institutions, investigators, industry sponsors, and scientific journals, little is known about the perspectives of potential research participants. METHODS:The authors surveyed potential research participants over the internet, using the Harris Interactive Chronic Illness Database. A potential research participant was defined by: (1) self report of diagnosis by a health care professional and (2) willingness to participate in clinical trials. Email invitations were sent to 20 205 persons with coronary artery disease, breast cancer, or depression; a total of 6363 persons were screened; of these, 86% or 5478 met inclusion criteria and completed the survey. The outcome measures were respondents' ratings on: importance of knowing conflict of interest information, whether its disclosure ought to be required, and its effect on willingness to participate-across seven widely discussed scenarios of financial conflicts of interest (ranging from commercial funding to equity ownership). RESULTS:Majority responded that knowing conflict of interest information was "extremely" or "very" important; a larger majority felt financial conflicts of interest should be disclosed as part of informed consent (64% to 87%). In all seven scenarios, a majority was still willing to participate but in some scenarios a sizable minority would be wary of participation. Respondents were more wary of individual than institutional conflicts of interest. Illness group and sociodemographic factors had modest effects and did not affect the main trends. CONCLUSIONS:The prevailing practice of non-disclosure of financial conflicts of interest in clinical research appears contrary to the values of potential research participants.
journal_name
J Med Ethicsjournal_title
Journal of medical ethicsauthors
Kim SY,Millard RW,Nisbet P,Cox C,Caine EDdoi
10.1136/jme.2002.001461keywords:
subject
Has Abstractpub_date
2004-02-01 00:00:00pages
73-9issue
1eissn
0306-6800issn
1473-4257journal_volume
30pub_type
杂志文章abstract::In this paper, I respond to criticisms by John Harris, contained in a commentary on my article "Harris, harmed states, and sexed bodies", which appeared in the Journal of Medical Ethics, volume 37, number 5. I argue that Harris's response to my criticisms exposes the strong eugenic tendencies in his own thought, when ...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/jme.2011.045021
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:To prevent the planet from catastrophic global warming a reduction of greenhouse gas emissions to net zero is required. Thus, divestment from fossil fuels must be a strategic interest for health insurers. The aim of this study was to analyse the implementation of environmental, social and governance (ESG) cr...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106381
更新日期:2020-10-13 00:00:00
abstract::Giubilini and Minerva argue that the permissibility of abortion entails the permissibility of infanticide. Proponents of what we refer to as the Birth Strategy claim that there is a morally significant difference brought about at birth that accounts for our strong intuition that killing newborns is morally impermissib...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106781
更新日期:2020-10-26 00:00:00
abstract::Clinical trials emerged in rapid succession as the COVID-19 pandemic created an unprecedented need for life-saving therapies. Fair and equitable subject selection in clinical trials offering investigational therapies ought to be an urgent moral concern. Subject selection determines the distribution of risks and benefi...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106590
更新日期:2021-01-01 00:00:00
abstract::The 'right to the truth' involves disclosing all the pertinent facts to a patient so that an informed decision can be made. However, this concept of a 'right to the truth' entails certain ambiguities, especially since it is difficult to apply the concept in medical practice based mainly on current evidence-based data ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2009.033340
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:A statute enacted in 2005 modified the legislative framework of the rights of terminally ill persons in France. Ten years after the EURONIC study, which described the self-reported practices of neonatal caregivers towards ethical decision-making, a new study was conducted to assess the impact of the new law ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2010.038356
更新日期:2011-04-01 00:00:00
abstract::Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical ...
journal_title:Journal of medical ethics
pub_type: 杂志文章,评审
doi:10.1136/jme.2005.013532
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVES:To study the attitudes of health care staff in four postcommunist countries towards taking gifts from their clients--and their confessed experience of actually taking such gifts. DESIGN:Survey questionnaire administered to officials including health care staff, supplemented by focus-group discussions with t...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.26.5.305
更新日期:2000-10-01 00:00:00
abstract::Too many people now have access to confidential medical information. Patients are becoming justifiably wary and the doctor-patient relationship is deteriorating. We can avert the developing crisis by allowing patients to keep their own medical records at home. This will ensure that confidentiality is respected and tha...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.10.1.27
更新日期:1984-03-01 00:00:00
abstract::We propose a principle of sustainability to complement established principles used for justifying healthcare resource allocation. We argue that the application of established principles of equal treatment, need, prognosis and cost-effectiveness gives rise to what we call negative dynamics: a gradual depletion of the v...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106644
更新日期:2021-02-01 00:00:00
abstract::In the context of military medical care, Eisenstein and colleagues have introduced the notion 'left of bang intervention in trauma', which refers to interventions administered before trauma to reduce morbidity and mortality after injury. This paper responds to Eisenstein and colleagues' ethical analysis of such interv...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2017-104584
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Future HIV vaccine efficacy trials with adolescents will need to ensure that participants comprehend study concepts in order to confer true informed assent. A Hepatitis B vaccine trial with adolescents offers valuable opportunity to test youth understanding of vaccine trial requirements in general. METHOD...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2012-101286
更新日期:2013-06-01 00:00:00
abstract::In a recent article in this journal, Anna Christensen raises an 'Epicurean challenge' to Don Marquis' much-discussed argument for the immorality of abortion. According to Marquis' argument, abortion is pro tanto morally wrong because it deprives the fetus of 'a future like ours'. Drawing on the Epicurean idea that dea...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2019-105771
更新日期:2020-04-01 00:00:00
abstract::The author responds to Professor Kottow's criticisms, explaining numerous errors and misconceptions. ...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/jme.25.4.344
更新日期:1999-08-01 00:00:00
abstract::The current COVID-19 pandemic has raised many questions and dilemmas for modern day ethicists and healthcare providers. Are physicians, nurses and other healthcare workers morally obligated to put themselves in harm's way and treat patients during a pandemic, occurring a great risk to themselves, their families and po...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106294
更新日期:2020-07-01 00:00:00
abstract::Non-therapeutic circumcision violates boys' right to bodily integrity as well as to self-determination. There is neither any verifiable medical advantage connected with the intervention nor is it painless nor without significant risks. Possible negative consequences for the psychosexual development of circumcised boys...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2012-101284
更新日期:2013-07-01 00:00:00
abstract::Debate continues over the acts/omissions doctrine, and over the concepts of duty and charity. Such issues inform the debate over the moral permissibility of euthanasia. Recent papers have emphasised moral sensitivity, medical intuitions, and sub-standard palliative care as some of the factors which should persuade us ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.16.1.28
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVES:To assess whether UK and US health care professionals share the views of medical ethicists about medical futility, withdrawing/withholding treatment, ordinary/extraordinary interventions, and the doctrine of double effect. DESIGN, SUBJECTS AND SETTING:A 138-item attitudinal questionnaire completed by 469 UK...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/jme.26.4.254
更新日期:2000-08-01 00:00:00
abstract::Anne Barnhill and Franklin Miller dispute my claim that the prescriptions of placebo treatments to patients are not typically deceptive, and do not typically violate the patients' informed consent. However, Barnhill and Miller seriously mischaracterise my position in two ways, as well as failing to show that the proce...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2015-103082
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To demonstrate Japanese doctors' and nurses' attitudes towards and practices of voluntary euthanasia (VE) and to compare their attitudes and practices in this regard. DESIGN:Postal survey, conducted between October and December 1999, using a self-administered questionnaire. PARTCIPANTS: All doctor members an...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.27.5.324
更新日期:2001-10-01 00:00:00
abstract::This paper investigates the efficiency of application of medical ethics principles in the practice of artificial insemination by donors (AID) in China, in a culture characterised by traditional ethical values and disapproval of AID. The paper presents the ethical approach to AID treatment as established by the Reprodu...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2004.007831
更新日期:2005-06-01 00:00:00
abstract::We analyse the system of ethical review of human research in the Baltic States by introducing the principle of equivalent stringency of ethical review, that is, research projects imposing equal risks and inconveniences on research participants should be subjected to equally stringent review procedures. We examine seve...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2009.035030
更新日期:2010-07-01 00:00:00
abstract::In a recent article, Udo Schuklenk and Suzanne van de Vathorst argued in favour of a legal option of physician-assisted death for patients with 'treatment-resistant' depression. In this commentary, I contend that their argument neglects the important consideration of the professional integrity of physicians. In light ...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2015-103060
更新日期:2015-11-01 00:00:00
abstract::On 9 May 2005, the Israeli Ministry of Health issued guidelines spelling out the conditions under which sex selection by preimplantation genetic diagnosis (PGD) for social purposes is to be permitted in Israel. This article first reviews the available medical methods for sex selection, the preference for children of a...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2007.023226
更新日期:2008-09-01 00:00:00
abstract::In this article, we discuss the ethical dimensions for the prescribing behaviours of opioids for a chronic pain patient, a scenario commonly witnessed by many physicians. The opioid epidemic in the USA and Canada is well known, existing since the late 1990s, and individuals are suffering and dying as a result of the e...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2018-105099
更新日期:2019-04-01 00:00:00
abstract::My sexual rights puzzle according to which positive sexual rights are not compatible with negative sexual rights has been recently criticised in the Journal of Medical Ethics by Steven J Firth, who has put forward three objections to the puzzle. In this brief response, I analyse and reject each of these three objectio...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2019-105642
更新日期:2020-05-01 00:00:00
abstract::Teaching medical ethics to medical students in a pluralistic society is a challenging task. Teachers of ethics have obligations not just to teach the subject matter but to help create an academic environment in which well motivated students have reinforcement of their inherent good qualities. Emphasis should be placed...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.20.4.239
更新日期:1994-12-01 00:00:00
abstract::Downie comments on Sieghart's article, "Professions as the conscience of society" (Journal of Medical Ethics 1985 Sep; 11(3): 117-122). He charges that Sieghart is blurring empirical, conceptual, and moral claims when he contends that the professional relationship is unique in that "altruism is paramount and self-int...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.12.2.64
更新日期:1986-06-01 00:00:00
abstract::The advent of prenatal genetic diagnosis has sparked debates among ethicists and philosophers regarding parental responsibility towards potential offspring. Some have attempted to place moral obligations on parents to not bring about children with certain diseases in order to prevent harm to such children. There has b...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2010.039230
更新日期:2011-05-01 00:00:00
abstract::Artificial intelligence (AI) is expected to revolutionise the practice of medicine. Recent advancements in the field of deep learning have demonstrated success in variety of clinical tasks: detecting diabetic retinopathy from images, predicting hospital readmissions, aiding in the discovery of new drugs, etc. AI's pro...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2019-105935
更新日期:2020-07-01 00:00:00