Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen.

abstract：:Antibody formation in rabbits against sheep erythrocytes (SRBC) was suppressed after injection of anti-SRBC IgG. Suppression did not occur, however, if the injected IgG had an allotypic marker to which the rabbits possessed circulating antibody. ...

journal_title：Scandinavian journal of immunology

authors： Jerne D,Aasted B

更新日期：1976-01-01 00:00:00

abstract：:The epidermis has been identified as an important site for the initiation of immunological events. In addition to the macrophage-like Langerhans cells, keratinocytes within the epidermal cells have been shown to act as immunoregulatory cells through the secretion of cytokines such as epidermal cell-derived thymocyte-a...

journal_title：Scandinavian journal of immunology

authors： Luger TA,Köck A,Danner M

更新日期：1985-05-01 00:00:00

abstract：:Cockroaches have been identified as one of the major indoor allergens inducing perennial rhinitis and asthma. Per a 1s are a group of the major allergens from American cockroach. Although Per a 1s are major allergens from American cockroach, factors contributing to the allergenicity of Per a 1s are still poorly define...

journal_title：Scandinavian journal of immunology

authors： He S,Zhang Z,Zhang H,Wei J,Yang L,Yang H,Sun W,Zeng X,Yang P

更新日期：2011-09-01 00:00:00

abstract：:The relationship of velocity of blood flow to density and microanatomical distribution of inflammatory cells in the dermis was studied in 20 human tuberculin tests. Most positive reactions showed maximal blood flow velocities (measured as red blood cell (RBC) flux) at the centre of the reaction, but the two most inten...

journal_title：Scandinavian journal of immunology

authors： Swanson Beck J,Gibbs JH,Potts RC,Jawad ES,Kardjito T,Spence VA,Grange JM

更新日期：1989-01-01 00:00:00

abstract：:Matrix metalloproteinases are involved in leucocyte invasion into the central nervous system (CNS) during meningitis. The aim of the study was to determine whether there are differences in the expression patterns of matrix metalloproteinase-9 (MMP-9) and the tissue inhibitor of metalloproteinase-1 (TIMP-1) in the cere...

journal_title：Scandinavian journal of immunology

authors： Sulik A,Wojtkowska M,Oldak E

更新日期：2008-09-01 00:00:00

abstract：:We describe the effects of treatment with topical steroids or dithranol on T and dendritic cells in the skin of patients with chronic plaque psoriasis. Resolution of lesions by both types of topical treatments was accompanied by a marked decrease in epidermal T cells. In steroid treated lesions there was also a reduct...

journal_title：Scandinavian journal of immunology

authors： Baker BS,Swain AF,Griffiths CE,Leonard JN,Fry L,Valdimarsson H

更新日期：1985-11-01 00:00:00

abstract：:We have examined the frequencies of T gamma delta cells in blood, synovial fluids, and synovial membranes of patients with rheumatoid arthritis (RA) and in blood from age-matched controls. Immunocytochemical and immunohistochemical techniques were used with monoclonal antibodies BB3 and A13 to define a major and minor...

journal_title：Scandinavian journal of immunology

authors： Smith MD,Bröker B,Moretta L,Ciccone E,Grossi CE,Edwards JC,Yüksel F,Colaco B,Worman C,Mackenzie L

更新日期：1990-12-01 00:00:00

abstract：:The tumour necrosis factor-α (TNF-α) promoter -308 A/G polymorphism plays an important role in the aetiology of systemic lupus erythematosus (SLE). Several studies have estimated the association between TNF-α -308 A/G and SLE risk. However, results were inconsistent. A case-control study was carried out to explore the...

journal_title：Scandinavian journal of immunology

authors： Yang ZC,Xu F,Tang M,Xiong X

更新日期：2017-03-01 00:00:00

abstract：:Inflammatory infiltrates in sciatic nerves during the acute phase of experimental allergic neuritis in the Lewis rat have been characterized with regard to occurrence and distribution of Ia-expressing cells and T-lymphocyte subsets by the help of an immunohistochemical double-staining technique, enabling the simultane...

journal_title：Scandinavian journal of immunology

authors： Olsson T,Holmdahl R,Klareskog L,Forsum U

更新日期：1983-10-01 00:00:00

abstract：:A heterologous antiserum (antiserum 7420) against B-lymphocyte antigen(s) was raised in a rabbit by immunization with peripheral blood lymphocytes from a patient with chronic lymphocytic leukaemia (CLL). After absorptions with pooled normal human serum, IgA, IgD, and IgM M-components, the fluorescein isothiocyanate-co...

journal_title：Scandinavian journal of immunology

authors： Berntorp E,Turesson I,Zettervall O

更新日期：1979-01-01 00:00:00

abstract：:The therapeutic use of the immune system to specifically attack tumours has been a long-standing vision among tumour immunologists. Recently, the use of checkpoint inhibitors to turn-off immunosuppressive signals has proven to be effective in enhancing T-cell reactivity against patient-specific neoantigens, resulting ...

journal_title：Scandinavian journal of immunology

authors： Sioud M

更新日期：2018-03-01 00:00:00

abstract：:Beta 2-glycoprotein I (beta 2-GPI) is a 50 kDa protein in human plasma composed of five repeating complement control protein modules thereby closely resembling complement factor H which has 20 such units. Both beta 2-GPI and factor H (150 kDa) have binding sites for negatively charged polyions. beta 2-GPI has been sho...

journal_title：Scandinavian journal of immunology

authors： Puurunen M,Jokiranta S,Vaarala O,Meri S

更新日期：1995-11-01 00:00:00

abstract：:Polymorphonuclear cell function tests were performed in 340 patients with recurrent unexplained infections. Serum-dependent defects in phagocytosis and intracellular killing of Candida albicans (Candida opsonin and procidin defects) were specifically associated with susceptibility to recurrent pyogenic infections, Can...

journal_title：Scandinavian journal of immunology

authors： Parkin JM,Bridges J,Sloper KS,Warner JO,Pinching AJ

更新日期：1991-01-01 00:00:00

abstract：:TIM-3 is a member of the TIM (T-cell immunoglobulin domain and mucin domain) family, which plays an important role in TH1 responses and autoimmune diseases. In this study, we cloned and characterized the porcine TIM-3 gene. Real-time PCR showed little expression of porcine TIM-3 in muscle and stomach, low expression i...

journal_title：Scandinavian journal of immunology

authors： Zhao W,Li Y,Wang Z,Li K,Yang S

更新日期：2011-01-01 00:00:00

abstract：:Mycobacterium tuberculosis (MTB) secretory proteins are generally considered important antigens for immune protection against tuberculosis (TB). An 8.3-kDa secretory antigen of MTB and Mycobacterium bovis bacillus Calmette-Guérin (BCG), called SA5K, was recently identified and cloned in our laboratory. In this report,...

journal_title：Scandinavian journal of immunology

authors： Batoni G,Bottai D,Esin S,Florio W,Pardini M,Maisetta G,Freer G,Senesi S,Campa M

更新日期：2002-07-01 00:00:00

abstract：:The authors have previously reported on the ability of A60, an immunodominant antigenic complex of Mycobacterium bovis BCG, to prevent cancer development in mice challenged with EMT 6 tumour cells. Such effect proved to rely on neoplastic cell lysis by cytolytic T lymphocytes and activated macrophages. The involvement...

journal_title：Scandinavian journal of immunology

authors： Maes H,Cocito C

更新日期：1996-10-01 00:00:00

abstract：:B cells are in analogy with T cells capable of expressing functional IL-2 receptors. IL-2R alpha-chain (CD25) positive T cells have been studied in detail but not much is known about CD25 positive B cells. The aim of this study was to examine the phenotypic properties of the CD25 expressing B cells collected from diff...

journal_title：Scandinavian journal of immunology

authors： Amu S,Gjertsson I,Tarkowski A,Brisslert M

更新日期：2006-11-01 00:00:00

abstract：:Age and gender-related variability of main lymphocyte subsets (T, B and NK cell absolute counts and percentages from Ly; T4, T8 and DN cell absolute counts and percentages from lymphocytes and from T cells; T4:T8 and T:B ratios) was studied in a large cohort of pediatric patients (2 days - 17 years) at yearly interval...

journal_title：Scandinavian journal of immunology

authors： Nikulshin S,Kundzina L,Tolstikova I,Gravele D,Prokofjeva T,Gardovska D

更新日期：2018-06-23 00:00:00

abstract：:The recombinant bacillus Calmette-Guérin (rBCG) secretion system utilizing an extracellular alpha antigen of Mycobacterium kansasii (alpha-K) was characterized biochemically and immunologically. The human immunodeficiency virus type 1 (HIV-1) p17gag B cell epitope fused to alpha-K was secreted in extremely large amoun...

journal_title：Scandinavian journal of immunology

authors： Wada N,Ohara N,Kameoka M,Nishino Y,Matsumoto S,Nishiyama T,Naito M,Yukitake H,Okada Y,Ikuta K,Yamada T

更新日期：1996-02-01 00:00:00

abstract：:Cellular immune response and delayed-type hypersensitivity reactions are considered to play a major role in the immunopathogenesis of pulmonary tuberculosis (PTB). But the exact mechanism is still to be clarified. Th1 cells are mainly involved in cellular immune responses in PTB and provide a normal healing process wi...

journal_title：Scandinavian journal of immunology

authors： Aktas E,Ciftci F,Bilgic S,Sezer O,Bozkanat E,Deniz O,Citici U,Deniz G

更新日期：2009-09-01 00:00:00

abstract：:Pemphigus vulgaris is a cutaneous autoimmune disease in which the occurrence of autoantibodies directed against desmoglein-3 and other self-antigens has been well established in patient sera. However, V-region interactions (connectivity) of serum IgG and IgM have not been analysed to date. In this report, it has been ...

journal_title：Scandinavian journal of immunology

authors： Pacheco-García U,Tovar-Rivera T,Padierna-Olivos L,Rojas-Espinosa O,Sánchez-Colón S,Gutiérrez-Armenta M,Rivera-Benítez C,Masso-Rojas F,Sánchez-García FJ

更新日期：1999-04-01 00:00:00

abstract：:Rheumatoid arthritis synovial fluid (RA-SF) contains a distinct biological activity that selectively induces IgG2b production in LPS-activated murine B blasts. This IgG2b inducing factor (IgG2bIF) acts directly on purified LPS-activated B blasts from normal and Bruton's tyrosine kinase-defective CBA/N mice. In order t...

journal_title：Scandinavian journal of immunology

authors： Lettesjö H,Ridderstad A,Möller E

更新日期：1997-01-01 00:00:00

abstract：:Cells of the mononuclear phagocytic system (MPS) were described as playing a decisive role in amyloidogenesis. A relationship between the amyloid enhancing factor (AEF) and MPS cells was suggested and recently AEF activity was attributed to a serine esterase (SE) of leucocytic origin. In the present study, no correlat...

journal_title：Scandinavian journal of immunology

authors： Niewold TA,Gruys E,Kisilevsky R,Shirahama TS

更新日期：1991-07-01 00:00:00

abstract：:X-irradiated (250 rad), cyclophosphamide-treated or ATx A mice injected with syngeneic trinitrophenylated spleen cells (TNP-SC) and footpad challenged with syngeneic lymphoblasts generated delayed-type hypersensitivity (DTH) responses 24, 48 and 72 h after challenge. The syngeneic-DTH (syn-DTH) response was mediated b...

journal_title：Scandinavian journal of immunology

authors： Tarcic N,Baler R,Naor D

更新日期：1984-11-01 00:00:00

abstract：:Our data on peripheral blood T cells from Motor neuron disease (MND) patients indicate major immunological disturbances linked to this disease. Both CD4+ and CD8+ T-cell subsets display an increased fraction of cells showing activation markers compared to controls, indicating an unusually high level of activity in bot...

journal_title：Scandinavian journal of immunology

authors： Katchar K,Osorio L,Conradi S,Wigzell H,Gigliotti D

更新日期：2001-07-01 00:00:00

abstract：:Sixteen plasma proteins were studied in the supernatants from 20 successive washings of human leucocytes by a new sensitive immunoelectrophoretic method. In the first few supernatants a fast and parallel decrease in concentration of all proteins took place, but for 11 proteins this was followed by a phase of slow decr...

journal_title：Scandinavian journal of immunology

authors： Andersen MM

更新日期：1982-04-01 00:00:00

abstract：:Colon cancer (CC) is one of the most common malignancies in the Western world. Although surgical resection is the first choice worldwide, at this point an effective approach for the treatment of patients with metastasis and cancer recurrence post-operation has not yet been found. The aim of this study was to investiga...

journal_title：Scandinavian journal of immunology

authors： Xu F,Ye YJ,Cui ZR,Wang S

更新日期：2005-04-01 00:00:00

abstract：:Fenugreek is a legume mostly used as a spice in Indian-style cooking. Although it has been used since ancient times, its allergenicity has only been reported in the last two decades. It poses special problems as an emerging and often hidden allergen. Fenugreek exposure may have serious implications also for individual...

journal_title：Scandinavian journal of immunology

authors： Vinje NE,Namork E,Løvik M

更新日期：2011-10-01 00:00:00

abstract：:The mechanisms by which glucocorticoids suppress immune responses have not yet been clearly defined. In steroid-sensitive pathological conditions, an increase in gamma delta T cells can occur in certain untreated systemic autoimmune disorders and seems to be a peristent feature in most cases of systemic lupus erythema...

journal_title：Scandinavian journal of immunology

authors： Spinozzi F,Agea E,Bistoni O,Travetti A,Migliorati G,Moraca R,Nicoletti I,Riccardi C,Paoletti FP,Vaccaro R

更新日期：1995-05-01 00:00:00

abstract：:Acanthamoeba polyphaga (AP) is ubiquitous in nature and frequently infects humans. AP has some features, such as persistence, which makes it an attractive candidate in studies of a possible infectious aetiology in rheumatoid arthritis (RA). In this study the occurrence of AP-specific antibodies was compared between RA...

journal_title：Scandinavian journal of immunology

authors： Jeansson S,Kvien TK

更新日期：2001-06-01 00:00:00