Abstract：
:The organic extracts of leaves and roots of five plants used for treating malaria in Central, Nairobi and Rift Valley Provinces, Kenya were tested for brine shrimp lethality and in vitro antiplasmodial activity against chloroquine sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 60% were toxic to the brine shrimp (LC(50)<30 microg/ml) and eight out of ten plant parts (80%) showed in vitro antiplasmodial activity (IC(50)<50 microg/ml). Among the extracts screened, the leaves of Cyathula polcephala had the highest toxicity to the brine shrimp (LC(50)=2.9 microg/ml) while the leaves of Pentas longiflora had the best antiplasmodial activity (IC(50)=11. /ml). The plant extracts with low IC(50) values are potential sources for novel antiplasmodial compounds.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Wanyoike GN,Chhabra SC,Lang'at-Thoruwa CC,Omar SAdoi
10.1016/j.jep.2003.09.047keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
129-33issue
1eissn
0378-8741issn
1872-7573pii
S0378874103003635journal_volume
90pub_type
杂志文章abstract：:A standardized mixture of Chinese herbs has recently been demonstrated to be an effective treatment for chronic atopic eczema in placebo controlled trials in the UK. Aqueous decoctions of this formulated mixture (PSE 222), the placebo mixture, and their component herbs were examined for antioxidant activity to determi...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(97)01510-9
更新日期：1997-04-01 00:00:00
abstract：:Twenty plants, belonging to sixteen families, used in traditional New Caledonian and Vanuatu medicine for treatment of symptoms potentially related to tuberculosis (cough, fever or inflammation) were screened for antimycobacterial activity. We also screened an original endemic plant, Amborella trichopoda, only member ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.09.008
更新日期：2005-01-04 00:00:00
abstract：UNLABELLED:Cinnabar is one of traditional Chinese medicines widely used in many Asian countries. It is also a medicine with potential toxicity especially when taking overdose. Up to date, studies on the mechanism of the biological activity of cinnabar were still insufficient. AIM OF THE STUDY:To investigate the possib...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.06.018
更新日期：2010-08-19 00:00:00
abstract：:Viscum album L. herbs are used for the treatment of various diseases. Apart from their immunostimulatory, antitumor, and hypotension inducing activities, anti-inflammatory effects has also been recorded in the literature. Since the immunostimulatory activity of mistletoe is mainly attributed to a stimulation of the mo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(98)00038-5
更新日期：1998-07-01 00:00:00
abstract：:The term epilepsy is collectively designated for a group of chronic central nervous system disorders characterized by spontaneous occurrence of seizures generally associated with the loss of consciousness and body movements (convulsions). The disease has its origin from an early age. Anticonvulsant drugs are used to c...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/0378-8741(88)90226-7
更新日期：1988-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Trillium tschonoskii rhizome (TTR), a medicinal herb, has been traditionally used to treat traumatic brain injury and headache in China. Although the potential neuroprotective efficacy of TTR has gained increasing interest, the pharmacological mechanism remains unclear. Steroid saponins a...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.01.006
更新日期：2018-04-06 00:00:00
abstract：:The flowers of Albizzia julibrissin are used as a sedative in oriental traditional medicine. The phytochemical study of this plant allowed the isolation of two flavonol glycosides, quercitrin (1) and isoquercitrin (2). The sedative activity of these compounds was evaluated, and both compounds 1 and 2 increased pentoba...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(99)00202-0
更新日期：2000-07-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Banana is a fruit with nutritional properties and also with acclaimed therapeutic uses, cultivated widely throughout the tropics as source of food and income for people. Banana peel is known by its local and traditional use to promote wound healing mainly from burns and to help overcome o...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2014.11.008
更新日期：2015-02-03 00:00:00
abstract：:Neurada procumbens is a desert plant in the Arabian Peninsula. It has been considered edible by Bedouin and has been used traditionally as a medicinal herb. During a screening test of Arabian plants, the aqueous extract of Neurada procumbens increased the blood pressure of anaesthetized normotensive rats when it was a...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2003.09.045
更新日期：2004-02-01 00:00:00
abstract：:Studies on ethnomedicobotany of Kandha tribe of Orissa, India, are scanty. In view of this the original ethno-botanical information and plant specimens were collected from the Kandhamal district of Orissa by visiting the area several times. The paper reports 27 plant species belonging to 24 families used in the treatm...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.06.024
更新日期：2005-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Danshen, root of Salvia miltiorrhiza (SM), has been traditionally used in Chinese medicine for the treatment of heart, abdomen, gurgling in the intestines, and relieving fullness. However, the effects of SM on intestine have rarely been done to date. AIM OF THE STUDY:To investigate the c...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2012.05.041
更新日期：2012-08-01 00:00:00
abstract：:Folk medicine practitioners in Perú employ plant preparations as wound-healing agents on superficial and internal wounds (gastric ulcers). The results of a scientific evaluation of the wound-healing activity of nine plants found in the Amazon jungle near Iquitos and in the Andes mountains is presented. The species stu...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(96)01500-0
更新日期：1997-02-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Bojungikki-tang is a traditional herbal medicine used to boost immunity and reduce fatigue. However, there is not enough scientific evidence about its toxicological safety profile to support its continued clinical application. AIM OF THE STUDY:The objective of this study was to investiga...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112551
更新日期：2020-04-24 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Origanum majorana L. (Lamiaceae) is commonly used in Moroccan folk medicine to treat infantile colic, abdominal discomfort and diarrhea. Liquid stools and abdominal discomfort observed in acute infectious diarrhea are the consequences of imbalance between intestinal water secretion and ab...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.09.005
更新日期：2019-07-15 00:00:00
abstract：:Tribulus terrestris L. (Zygophyllaceae) have been used as an aphrodisiac both in the Indian and Chinese traditional systems of medicine. Administration of Tribulus terrestris extract (TT) increased sexual behaviour and intracavernous pressure both in normal and castrated rats and these effects were probably due to the...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.08.030
更新日期：2005-01-04 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tongnao Decoction (TND) is a Chinese decoction approved and used in Jiangsu Province Hospital for the treatment of ischemic stroke. It shows conclusive efficiency in the improvement of neurologic impairment and activities of daily living of the patients. AIM OF THE STUDY:Recently, angiog...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112737
更新日期：2020-05-23 00:00:00
abstract：:The antiinflammatory (per os and topic) and analgesic (per os) properties of the aerial part of Proustia pyrifolia a species in danger of extinction were investigated, and the major compounds of two of its active extracts were isolated. In addition, the evaluation of cytotoxicity in three tumoral cell lines and the ac...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.02.012
更新日期：2005-05-13 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Yuk-Mi-Jihwang-Tang (YJT) has been popularly prescribed to treat aging related disorders over than hundreds of years in East Asia countries. AIM OF THE STUDY:To investigate possible modulatory actions of YJT on chronic restraint stress (CRS)-induced neurodegeneration on hippocampus neuro...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113102
更新日期：2020-10-05 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In this work, we study whether aqueous extracts from the roots of Mimosa albida Humb. & Bonpl. ex Willd, a plant known in the Highlands of Chiapas, Mexico as "Lotóm chíx" are endowed with both antinociceptive and anxiolytic effects. MATERIALS AND METHODS:ICR mice were systemically treate...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.07.010
更新日期：2013-09-16 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The rhizomes of Cyperus rotundus have been used as traditional folk medicine for the treatment of inflammatory diseases. However, the mechanism by which extract of rhizomes of Cyperus rotundus (ECR) elicits anti-inflammation has not been extensively investigated so far. The aim of the pre...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.07.062
更新日期：2011-10-11 00:00:00
abstract：:The antihypertensive action of a procyanidin glycoside isolated from Rhamnus lycioides aerial parts was studied in spontaneously and renal hypertensive rats. This compound, like 20 micrograms/kg i.v. of captopril, produced a very clear in vivo inhibition of angiotensin I converting enzyme when given at a dose of 3 mg/...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(91)90149-8
更新日期：1991-01-01 00:00:00
abstract：AIM OF THE STUDY:Fissistigma oldhamii (Hemsl.) Merr, a traditional Chinese herb medicine, is used for treating rheumatoid arthritis in China. In our previous study, an effective compound, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl) ethyl] propenamide (Z23), from this herb has showed potent immunosuppressive effects...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.09.026
更新日期：2008-12-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Poisonous plants comprise the third largest category of poisons known around the world. Other than affecting the humans directly, they are the major cause of economic losses in the livestock industry since the advent of civilisation. Aim of the present study was to collect and systematica...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.12.058
更新日期：2014-02-27 00:00:00
abstract：:Melissa officinalis L. (Labiatae), Morus alba L. (Moraceae), and Artemisia capillaris Thunb. (Compositae) are suggested to be involved in the regulation of hyperlipidemia. We hypothesized that Ob-X, a mixture of three herbs, Morus alba, Melissa officinalis and Artemisia capillaris [corrected] improves lipid metabolism...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.09.029
更新日期：2008-01-17 00:00:00
abstract：AIM OF THE STUDY:Er Xian Decoction (EXD), a traditional Chinese medicine formula, has long been used for the treatment of osteoporosis and menopausal syndrome in China. The present study was designed to investigate the antiosteoporotic constituents of EXD, and evaluate their antiosteoporotic effects in ovariectomized r...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.04.009
更新日期：2008-07-23 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Caesalpinia sappan is a medicinal plant native to China popularly used to treat chronic pelvic inflammation, dysmenorrhea and hysteromyoma. Its main bioactive component is brazilin which had presented antibacterial, anti-inflammatory and anti-platelet aggregation activities. To establish ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.08.054
更新日期：2014-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Hyangaa-Pyeongwi san is the most well known description in Traditional Chinese Medicine for treating functional gastrointestinal disorders. Functional dyspepsia (FD) is a main concern of intimidating quality of life (QoL) in recent days. Although many medicines have been developed to impr...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jep.2013.10.033
更新日期：2014-01-01 00:00:00
abstract：AIMS OF THE STUDY:This study investigated the anti-inflammatory and analgesic activities, and protoberberine alkaloid contents of ethanol extract of MO roots (MOR(EtOH)). MATERIALS AND METHODS:The analgesic activity of MOR(EtOH) was determined using acetic acid-induced writhing response and formalin test. The anti-inf...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.06.024
更新日期：2009-09-07 00:00:00
abstract：AIM OF THE STUDY:To investigate the hypoglycemic effects of Vaccinium bracteatum Thunb. leaves (VBTL) extract in streptozotocin-induced diabetic mice. MATERIALS AND METHODS:After administration of VBTL extract for 4 weeks, the body weight, organ weight, blood glucose (BG), insulin and plasma lipid levels of streptozot...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.05.031
更新日期：2010-08-09 00:00:00
abstract：:The present study was undertaken to evaluate the contraceptive efficacy of methanol extract of Dendrophthoe falcata Ettingsh (family-Loranthaceae), stem in male albino rats as reported in folk remedies. Adult proven fertile male rats were gavaged methanol extract of D. falcata stem at 50, 100 and 200mg/rat/day for 60 ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.02.022
更新日期：2007-05-30 00:00:00
