Abstract:
:The current study was initiated to define whether Tc-99m leukocyte imaging, compared to In-111 chloride imaging, could provide additional information on the hematopoietic activity of the bone marrow in diffuse hematologic disorders. A total of 11 patients with hematologic disorders were studied both with Tc-99m leukocytes and In-111 chloride. One patient with myelofibrosis showed disparate tracer distribution in the bone marrow between the two; Tc-99m leukocyte uptake in the central marrow was highly decreased, whereas In-111 chloride showed expanded marrow. The disparate results of granuloid hypoplasia and erythroid hyperplasia obtained by bone marrow biopsy and aspiration in this patient were thought to give an explanation for the radionuclide findings. The remaining 10 patients showed similar tracer distribution in the marrow, and the observation of hematopoietic cellularity confirmed by bone marrow biopsy and aspiration correlated well with the radionuclide findings. These results demonstrate that Tc-99m leukocytes may be a potential imaging agent for evaluating hematopoietic activity in the bone marrow, in particular granulopoietic activity.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Aburano T,Yokoyama K,Shuke N,Kinuya S,Takayama T,Michigishi T,Tonami N,Hisada Kdoi
10.1097/00003072-199212000-00007keywords:
subject
Has Abstractpub_date
1992-12-01 00:00:00pages
938-44issue
12eissn
0363-9762issn
1536-0229journal_volume
17pub_type
杂志文章abstract::The amino-terminal domain of fibronectin has a fibrin binding site and a site for covalent cross-linking to fibrin. This fibrin binding domain was isolated from human recombinant fibronectin and labeled with In-111; the final molecular weight was 12 kD. It was applied to a pilot study of 62 patients; 30 who were thoug...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00003072-199505000-00004
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVES:Talc pleurodesis can be offered to patients with hepatic hydrothorax. The authors wanted to determine their patient's eligibility for talc pleurodesis by excluding a pleural-peritoneal shunt. MATERIALS AND METHODS:The authors measured the size of the talc particles and matched them with the radionuclide par...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000134980.57598.5d
更新日期:2004-09-01 00:00:00
abstract::The unique information provided by radionuclide techniques allows the noninvasive characterization of primary tumors and tumor-like conditions of the liver. A thorough knowledge of the mechanisms of radiopharmaceutical localization and the histologic abnormalities present in each condition is required to optimally use...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198707000-00022
更新日期:1987-07-01 00:00:00
abstract::Gallium-67 distribution in normal patients is well known; it is also known that the concentration in some tissues may vary according to an individual physiologic stimulus. In this report, the case of a young woman is presented who was studied 15 days after a cesarean section and showed physiologic and pathologic Ga-67...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198402000-00011
更新日期:1984-02-01 00:00:00
abstract::A 57-year-old man presented with shortness of breath and ankle edema. Constrictive pericarditis with an unexplained mass surrounding the heart was diagnosed by ultrasound. Accordingly, F-FDG PET/CT was performed. Multiple PET-positive noduli and irregular tissue were located in the pericardium, with pleural fluid pres...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002349
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:This retrospective study aimed to correlate F-FDG uptake on PET/CT with isocitrate dehydrogenase enzyme isoform 1 (IDH1) mutation in patients with cerebral gliomas. Hierarchical interactions between factors affecting overall survival (OS) were also examined. METHODS:In 59 patients with glioma, the ratio of the...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002006
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Medullary thyroid cancer (MTC) is a rare but potentially life-threatening disease with limited therapeutic options. As a neuroendocrine tumor, MTC expresses somatostatin receptors, and therefore, somatostatin-labeled radiopharmaceuticals could be used to treat patients with MTC. OBJECTIVE:The aims of this s...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0000000000000628
更新日期:2015-02-01 00:00:00
abstract::Using serial perfusion lung scans, we have documented the opening up and closure of right-to-left intrapulmonary arteriovenous shunts over a period of several weeks in a patient with chronic alcoholic liver disease. The presence of the shunts correlates well with the severity of hypoxemia and the presence of nodular m...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198405000-00009
更新日期:1984-05-01 00:00:00
abstract:PURPOSE:The purpose of this case report is to demonstrate the utility of multimodality imaging in the diagnosis of infection within a retained prosthetic device in the posttransplant setting. MATERIAL AND METHODS:Autologous leukocytes were labeled in vitro with indium-111 oxine and were reinjected. Whole-body and SPEC...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200501000-00004
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Nuclear medicine techniques were used to show that the peripheral lymphatics are under autonomic control in much the same way as the blood vessels that supply the same anatomic region. METHODS:Three patients with complex regional pain syndrome type 1 (reflex sympathetic dystrophy) involving a lower extremity w...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199906000-00001
更新日期:1999-06-01 00:00:00
abstract::We describe the results of F-FDG PET/CT of 3 patients referred to our institution during the single day of Monday, March 23, 2020, for an initial assessment of cancer extension or for the therapeutic evaluation of chemotherapy of neoplastic pathology, with no obvious infectious or respiratory symptoms at the time of e...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003255
更新日期:2020-12-01 00:00:00
abstract::A 57-year-old man with a history of metastatic melanoma and sclerotic bone lesions seen on CT was referred for F NaF PET/CT evaluation of active skeletal metastases. While the bone lesions had no uptake and were therefore thought to represent sequela of previously treated disease, an unexpected area of F NaF uptake wa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000371
更新日期:2014-10-01 00:00:00
abstract::A 54-year-old man with mesenteric carcinoid tumor metastatic to the liver completed staging Ga-DOTATATE PET/CT demonstrating uptake in multiple hepatic lesions consistent with liver metastases with additional asymmetric increased uptake in the right greater than the left breast. Subsequent bilateral diagnostic mammogr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002597
更新日期:2019-10-01 00:00:00
abstract::A case of right ventricular aneurysm due to coronary artery disease in a 69-year-old male with no prior history of surgery or chest trauma is reported. The presence of the aneurysm was diagnosed by gated radionuclide angiography and confirmed by contrast angiography. This is the first description of an isolated right ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198702000-00003
更新日期:1987-02-01 00:00:00
abstract:PURPOSE:Tl-201 chloride has been used to image viable tumors in various sites of the body. There has been limited use of Tl-201 below the diaphragm because of normal uptake in the liver, spleen, kidneys, and intestines. The use of sequential Tl-201 and Tc-99m sulfur colloid in the detection and characterization of susp...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199612000-00007
更新日期:1996-12-01 00:00:00
abstract::The use of gallium scanning in the treatment of patients with AIDS has been well described. In this study, 27 HIV-infected patients (Walter Reed Staging Classification I-V) with normal chest roentgenograms were evaluated to determine the occurrence of thoracic gallium abnormalities in early HIV infection. SPECT was us...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199005000-00003
更新日期:1990-05-01 00:00:00
abstract::Chronic subdural hematoma (SDH) is difficult to diagnose by clinical manifestations only. Nonspecific neurologic symptoms and signs may lead physicians to make other diagnoses. Although head trauma is the most common cause, it may be considered insignificant or omitted due to its minor initial manifestations. We prese...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31819a1ed8
更新日期:2009-04-01 00:00:00
abstract::An 80-year-old woman was evaluated with F-fluorocholine PET/CT in suspicion of a parathyroid adenoma. No focal parathyroid tracer uptake suggestive of adenoma was found, and instead a unilateral multinodular goiter without elevated F-fluorocholine uptake was diagnosed. In addition, focal uptake was found in a cutaneou...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001972
更新日期:2018-04-01 00:00:00
abstract::The performance of Tc-99m MDP vs Tc-99m dicarboxypropane diphosphonate (DPD) was evaluated in 20 patients with various skeletal bone diseases. Each patient was investigated twice, with an interval of three days between studies and using the same protocol, hence each case served as its own control. The results were: In...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198602000-00006
更新日期:1986-02-01 00:00:00
abstract::Congenitally corrected transposition of the great arteries (CTGA) may constitute a pitfall for interpretation of radionuclide angiocardiography, since the two anatomic discordances cancel each other from a physiologic point of view. However, the unusual shape of the ventricles (due to ventricular discordance) and the ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198407000-00003
更新日期:1984-07-01 00:00:00
abstract::Contralateral cerebellar diaschisis, hypometabolism in the cerebellum contralateral to a cortical lesion, is a well described phenomenon in patients with stroke and brain tumor. However, few reports exist of patients with cerebellar lesions with the finding of contralateral cortical hypometabolism. The authors present...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/00003072-200006000-00008
更新日期:2000-06-01 00:00:00
abstract::Two patients with myocardial sarcoidosis are presented, both of whom underwent SPECT imaging with Tl-201 and Ga-67. The first had Ga-67 myocardial uptake with a Tl-201 defect, which disappeared with corticosteroid therapy. The second had multiple Tl-201 defects without Ga-67 uptake, which persisted despite corticoster...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199006000-00009
更新日期:1990-06-01 00:00:00
abstract::Bone scintigraphy is sensitive for detecting bone metastases in patients with malignancies. However, it is often difficult to differentiate bone metastases from other nonmalignant lesions. We encountered a patient with a history of breast cancer who showed substantial elevation of tumor markers 4 years after surgery. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000170058.73956.82
更新日期:2005-08-01 00:00:00
abstract::An 85-year-old woman who had an invasive ductal carcinoma of the breast and elevated alkaline phosphatases (420 U/L) was referred for Tc-99m MDP bone scintigraphy for initial evaluation of skeletal metastases. Bone symptoms were limited to chronic pain in both knees. A bone scan revealed pagetoid findings in both calc...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000247783.43949.c1
更新日期:2006-12-01 00:00:00
abstract::Alpha-aminoisobutyric acid (AIB), a synthetic, nonmetabolized amino acid which is rapidly transported into viable cells by the A-type or alanine-preferring amino acid transport system, has been labeled with the short-lived, positron-emitting radionuclide carbon-11. Carbon-11 labeled AIB is currently being evaluated as...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198701000-00005
更新日期:1987-01-01 00:00:00
abstract::Osteitis condensans ilii (OCI) is a benign cause of low back pain for which no clear etiology has been identified. We report cases of 2 women with breast cancer referred for F-NaF PET/CT for skeletal staging. Both cases show characteristic findings of OCI on CT images, with F-NaF PET uptake in symptomatic patient and ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003371
更新日期:2020-11-10 00:00:00
abstract:PURPOSE:Sentinel lymph node biopsy (SLNB) has been described as a minimally invasive method for lymph node staging in patients with a penile carcinoma and nonpalpable inguinal nodes in national and international guidelines of involved professional societies. However, this method is rarely used. The aim of this study wa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001268
更新日期:2016-08-01 00:00:00
abstract::We present a 73-year-old man with a new diagnosis of right upper lung adenocarcinoma. Right elbow x-ray and Tc-99m MDP whole body bone scan were performed due to a reddish, swollen, and painful right forearm for 1 week. X-ray, performed on March 25, 2008, showed an osteolytic lesion in the proximal right radius with s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181b53a21
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the role of ⁶⁸Ga-DOTANOC (⁶⁸Gallium-labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI³-octreotide) PET/CT for localization of the primary tumor in patients with carcinoma of unknown primary of neuroendocrine origin. MATERIAL AND METHODS:Twenty patients (median age, 55 years...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31823ea730
更新日期:2012-03-01 00:00:00
abstract:ABSTRACT:A 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white adipose tissue and decreased visceral activity on interim posttreatment FDG PET/CT. This altered biodistribution was attributed to administration of the chemother...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003340
更新日期:2021-03-01 00:00:00