Technetium-99m MDP vs technetium-99m dicarboxypropane diphosphonate. A clinical comparison in various pathologic conditions.

Abstract:

:The performance of Tc-99m MDP vs Tc-99m dicarboxypropane diphosphonate (DPD) was evaluated in 20 patients with various skeletal bone diseases. Each patient was investigated twice, with an interval of three days between studies and using the same protocol, hence each case served as its own control. The results were: In a subjective interpretation by five independent and experienced investigators, the difference between agents was small, yet in favor of MDP. Region of interest (ROI) analysis of the pooled results in 74.4% of all cases shows a higher bone lesion to normal bone ratio (BL/NB), and in 79.3% of all cases, a better bone lesion to soft tissue ratio (BL/ST) with Tc-99m MDP. When considering pathology types separately, the BL/NB ratio of Tc-99m MDP was 17.7% higher than the one of Tc-99m DPD in metastases, 9.5% higher in rheumatoid arthritis, 2.8% higher in metabolic diseases, and 24% higher in bone fractures. Student's paired t test on the pooled BL/NB ratios shows a difference of 15.5% for Tc-99m MDP, significant at P = 0.00155. The overall results of our study favor Tc-99m MDP.

journal_name

Clin Nucl Med

authors

Godart G,Durez M,Bevilacqua M,Abramovici J,Robience Y

doi

10.1097/00003072-198602000-00006

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

92-7

issue

2

eissn

0363-9762

issn

1536-0229

journal_volume

11

pub_type

杂志文章
  • Technetium-99m RBC venography revealing bilateral iliac vein obstruction.

    abstract::Tc-99m RBC venography demonstrated bilateral iliac vein obstruction with subsequent collateral flow through the internal iliac veins into the internal and perimuscular rectal plexuses. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198608000-00022

    authors: Lisann NM,Palestro CJ,Benua RS

    更新日期:1986-08-01 00:00:00

  • Normal variants of a photon-deficient area in the lower sternum demonstrated by bone SPECT.

    abstract:PURPOSE:A highly variable normal appearance of the sternal area makes interpretation difficult on planar bone imaging. These normal variants occur especially in the area above the xiphoid process of the sternum in which an oval photopenic area on anterior planar images may be seen. This finding is most likely caused by...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199904000-00006

    authors: Han JK,Shih WJ,Stipp V,Magoun S

    更新日期:1999-04-01 00:00:00

  • Radioisotope bone scanning in chronic osseous sarcoidosis.

    abstract::Sarcoidosis is rarely recognized as an osseous manifestations alone. Patients with osseous involvement usually have a chronic multivisceral form of the disease. The authors report a case of osseous sarcoidosis without other visceral involvement. A bone scan was requested to evaluate the extent of the bone involvement ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199605000-00004

    authors: Benelhadj S,Patrois F,Duet M,Bérolatti B,Mundler O

    更新日期:1996-05-01 00:00:00

  • Tc-99m HMPAO SPECT in a cerebral gunshot wound.

    abstract::The authors examined regional cerebral blood flow by using Tc-99m HMPAO SPECT studies in a patient who received a gunshot wound to the brain. Although the presence of the retained bullet's fragments adversely affected the quality of CT images and contraindicated MRI studies, the SPECT examination did not have the same...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199408000-00012

    authors: Valle G,Bonetti MG,Ciritella P,Di Fazio P,Barbano F,Perrone E

    更新日期:1994-08-01 00:00:00

  • Renal scintigraphic findings in a case of transplant renal vein thrombosis.

    abstract::Renal vein thrombosis is a rare complication of renal transplantation. The scintigraphic features of a documented case of renal vein thrombosis studied with Tc-99m DTPA and the differential diagnosis relevant to these findings are discussed. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198806000-00009

    authors: Myerly KF,Kirchner PT

    更新日期:1988-06-01 00:00:00

  • 177Lu-DOTATATE Therapy in Radioiodine-refractory Differentiated Thyroid Cancer: A Single Center Experience.

    abstract:INTRODUCTION:Patients with radioiodine-refractory differentiated thyroid cancer (RrDTC) have a rather poor prognosis and are in need of novel treatments. As RrDTCs can in some cases express somatostatin receptors (SSRT), targeting of these receptors by Ga/Lu-DOTATATE could evolve as a novel theranostic option. METHODS...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002219

    authors: Roll W,Riemann B,Schäfers M,Stegger L,Vrachimis A

    更新日期:2018-10-01 00:00:00

  • Automated volume determination of the liver and spleen from Tc-99m colloid SPECT imaging. Quantification of the liver functional and nonfunctional tissue in disease.

    abstract::An automated volume determination program using SPECT imaging with Tc-99m has been validated by both phantom and patient studies. Its use for monitoring change of function of the liver and change in tumor mass during different therapy regimes has been assessed. The technique is not restricted to the estimation of the ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199007000-00009

    authors: Kavanagh GJ,Kavanagh JT,Kavanagh PB,Irwin LE,Perkins AC,Swanson LA

    更新日期:1990-07-01 00:00:00

  • Nasopharyngeal tuberculosis mimicking nasopharyngeal carcinoma on (18)F-FDG PET/CT in a young patient.

    abstract::A 30-year-old woman presented with a painless left upper neck swelling for more than a week. Fibrolaryngoscope examination suggested nasopharyngeal carcinoma. FDG PET/CT was performed for an initial staging, which revealed intense activity in the soft tissue mass in the nasopharynx and cervical lymph nodes. However, b...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000656

    authors: Zhang Y,Chen Y,Huang Z,Cai L,Wu J

    更新日期:2015-06-01 00:00:00

  • False-positive radionuclide hepatobiliary imaging following cystic duct stone removal.

    abstract::The authors report a case in which a radionuclide hepatobiliary image was falsely indicative of cystic duct obstruction in a patient with an indwelling cholecystostomy tube and an externalized gallbladder-duodenal stent. Cystic duct patency was demonstrated radiographically shortly before and after the radionuclide st...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198903000-00001

    authors: Zagoria RJ,Cowan RJ,Dyer RB,Herrera M

    更新日期:1989-03-01 00:00:00

  • 18F-FDG PET/CT imaging of Sister Mary Joseph's nodule.

    abstract::An 82-year-old woman was followed up for an uterine cervical adenocarcinoma treated by surgery. A whole-body fluorodeoxyglucose positron emission tomography study revealed a pathologic fluorodeoxyglucose uptake located in the umbilicus associated to peritoneal carcinomatosis. Biopsy of the umbilical nodule demonstrate...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182443b0f

    authors: Métivier D Jr,Bonardel G,Rouquie D,Gontier E,Chargari C,Dechaud C,Foehrenbach H,Chapuis O

    更新日期:2012-05-01 00:00:00

  • Reflux in native kidneys mimicking urine leak postrenal transplant.

    abstract::A 19-year man underwent live related renal transplantation for end-stage renal disease. He was referred for a baseline renal scan on day 4. The urine output was satisfactory and the serum creatinine showed a decreasing trend. Renal dynamic scintigraphy with technetium-99m ethylenedicysteine demonstrated radiotracer ac...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000159684.38607.e3

    authors: Tripathi M,Chandrashekar N,Kumar R,Malhotra A

    更新日期:2005-05-01 00:00:00

  • Angiocardiography with the seven-pinhole collimator: evaluation of methodology and accuracy in assessing global and regional left ventricular function.

    abstract::Determination of left ventricular function with tomographic radionuclide angiocardiography using a seven-pinhole collimator was evaluated by comparing results of invasive contrast studies and planar multigated blood pool imaging to the tomographic study of 25 patients. LAO, seven-pinhole multigated blood pool acquisit...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198204000-00002

    authors: Myers RW,Bails RP,Reed VR,Price JM,Drasin E,Hill JD,Saphir JR

    更新日期:1982-04-01 00:00:00

  • Detection of protein bound vitamin B12 malabsorption. A case report and review of the literature.

    abstract::The Schilling test is used to identify the cause of vitamin B12 malabsorption in patients with low serum vitamin B12 levels. The initial step required for vitamin B12 absorption is a process of separation from the protein complexes of food. The crystalline Co-57 vitamin B12 used in the Schilling test does not reproduc...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00003072-199411000-00015

    authors: Lucas MH,Elgazzar AH

    更新日期:1994-11-01 00:00:00

  • Endotracheal metastasis from squamous cell cancer of the head and neck: PET/CT imaging.

    abstract::Lung cancer is the main malignancy with frequent endotracheal and endobronchial dissemination. Extrapulmonary sources of airway metastasis are less common, predominantly seen with breast, colorectal, and renal neoplasms. Head and neck cancer represents only a small fraction of tumors with tracheal luminal metastasis. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e31816a790a

    authors: Nguyen BD,Ram PC,Roarke MC

    更新日期:2008-05-01 00:00:00

  • Thyroid carcinoma presenting as an autonomous thyroid nodule.

    abstract::A case of follicular thyroid cancer appearing as an autonomous nodule on Tc-99m and I-123 thyroid scintigraphy is presented in addition to a pertinent review of the literature. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00003072-199005000-00006

    authors: Intenzo CM,Park CH,Cohen SN

    更新日期:1990-05-01 00:00:00

  • Scintigraphic findings in a primary cerebral amyloidoma.

    abstract::Bone, brain, and gallium scintigrams are presented of a 48-year-old man with biopsy-proven cerebral amyloidosis. Brain scintigraphy revealed a well-circumscribed accumulation of Tc-99m pertechnetate in the amyloidoma. Bone scintigraphy using Tc-99m methylenediphosphonate likewise exhibited increased activity in the sa...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198311000-00003

    authors: Moreno AJ,Brown JM,Brown TJ,Graham GD,Yedinak MA

    更新日期:1983-11-01 00:00:00

  • Diffuse Large B-Cell Lymphoma Infiltrating Limb Bones With a Few Lymphadenopathy Revealed on Whole-Body 18F-FDG PET/CT.

    abstract::A 74-year-old man presented to our hospital for a 2-month history of worsening feet and left hand swelling pain. Computed tomography reconstruction image and sagittal images of the left foot demonstrated multiple and irregular bone destruction. Orthopedic surgeon suspected tuberculosis or primary skeletal malignancy. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000755

    authors: Qiu L,Chen Y,Huang Z,Zhu Y,Wen Q

    更新日期:2015-07-01 00:00:00

  • Complete response of adult-onset CNS Langerhans cell histiocytosis documented on 18F-FDG PET/CT.

    abstract::We report a case of a 49-year-old woman with biopsy-proven multisystemic Langerhans cell histiocytosis (LCH) with hypothalamic involvement documented on F-FDG PET/CT. Chemotherapy with a combination of vinblastine, prednisolone, methotrexate, and 6-mercaptopurine was carried out. Two months later, a 90% reduction of t...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000994

    authors: Kruljac I,Balenović A,Gaćina P,Imashuku S,Vrkljan M

    更新日期:2015-12-01 00:00:00

  • Solitary Acute Inflammatory Demyelinating Lesion of the Cervical Spinal Cord Mimicking Malignancy on FDG PET/CT.

    abstract::A 43-year-old woman presented with numbness of the left hand and leg for 4 weeks. MRI of the spinal cord revealed an intramedullary lesion with central nodular enhancement at the C3 level. Primary tumor or metastasis of the cervical spinal cord was suspected. FDG PET/CT showed focal hypermetabolism of the spinal cord ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003287

    authors: Liu Q,Liu M,Bai Y,Dong A

    更新日期:2020-12-01 00:00:00

  • Transient unilateral reverse ventilation/perfusion mismatch in a patient with lung cancer.

    abstract::The authors report a transient, unilateral reverse ventilation/perfusion (V/P) mismatch in a patient with squamous cell lung cancer. The right lung was well perfused but not ventilated (unilateral reverse V/P mismatch). However, lung imaging performed 3 days later demonstrated the absence of both perfusion and ventila...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199209000-00003

    authors: Watanabe N,Hirano T,Inoue T,Matsumoto M,Oriuchi N,Tateno M,Matsumoto H,Nagamachi Y,Endo K

    更新日期:1992-09-01 00:00:00

  • Incidental lymph node visualization on bone scan due to subcutaneous infiltration of Tc-99m MDP. A potential for false positive interpretation.

    abstract::Soft tissue localization of radiotracer on bone scintigraphy may result in false-positive interpretations, if the activity overlies a bony structure. A case is presented in which special views and follow-up clarified the soft tissue nature of focal uptake in arm and axilla. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199303000-00004

    authors: Dogan AS,Rezai K

    更新日期:1993-03-01 00:00:00

  • Early Detection of Bone Metastasis in Small Cell Neuroendocrine Carcinoma of the Cervix by 68Ga-DOTATATE PET/CT Imaging.

    abstract::The neuroendocrine small cell carcinoma of the cervix is a rare malignancy that has a poor prognosis due to early lymphatic and hematogenous spread. We herein report a case of a 27- year-old woman who was referred for initial staging of a neuroendocrine small cell carcinoma with previous unremarkable structural imagin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001498

    authors: Damian A,Lago G,Rossi S,Alonso O,Engler H

    更新日期:2017-03-01 00:00:00

  • Incidental detection of gastrointestinal bleeding from an aortoenteric fistula on 99mTc leukocyte scintigraphy.

    abstract:: A 50-year-old-man with abdominal pain, who had undergone aortic aneurysm reconstructive surgery (aortic graft) 3 years before, was admitted to the hospital. A CT scan showed findings suggestive of perigraft infection. Scintigraphy with 99mTc-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes confirmed the dia...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182639bd9

    authors: Cortés J,Villaverde J,Garrido M,Pombo M,Ruibal A

    更新日期:2012-11-01 00:00:00

  • Painful knee joint prostheses: evaluation for loosening by combined radionuclide arthrography and transmission imaging.

    abstract:UNLABELLED:Interpretation of radionuclide arthrograms (RNA) of the knee after total knee joint replacement (TKR) may be difficult because of the lack of sufficient anatomic reference information. Additional transmission images may provide the necessary reference information required for correct interpretation of RNA of...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199710000-00001

    authors: Hayes AA,Cardaci G,Bower GD

    更新日期:1997-10-01 00:00:00

  • Methionine PET Might Be Reliable for the Detection of Low M-Protein-Producing Myelomas.

    abstract::C-methionine (MET) positron emission tomography (PET) is more sensitive than F-fluorodeoxyglucose (FDG)-PET for detecting myeloma lesion. Many clinical studies support this evidence mainly for multiple myeloma cases of IgG or IgA subtypes. However, this is not confirmed for low monoclonal protein-producing myelomas, s...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001821

    authors: Imataki O,Uchida S,Yokokura S,Uemura M,Kadowaki N

    更新日期:2017-11-01 00:00:00

  • Metastatic female adnexal tumor of possible wolffian origin (FATWO) of the appendix demonstrated by FDG PET/CT: the first reported case.

    abstract::Both female adnexal tumor of possible wolffian origin (FATWO) and metastasis to the appendix from any primary tumor are extremely rare entities. The appendiceal metastasis from FATWO has not been reported, and there is a lack of the literature regarding FDG PET/CT study in both. We reported the case of an appendiceal ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318203bc77

    authors: Liu Y

    更新日期:2011-02-01 00:00:00

  • Identification of an infected left ventricular assist device after cardiac transplant by indium-111 WBC scintigraphy.

    abstract:PURPOSE:The purpose of this case report is to demonstrate the utility of multimodality imaging in the diagnosis of infection within a retained prosthetic device in the posttransplant setting. MATERIAL AND METHODS:Autologous leukocytes were labeled in vitro with indium-111 oxine and were reinjected. Whole-body and SPEC...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200501000-00004

    authors: Roman CD,Habibian MR,Martin WH

    更新日期:2005-01-01 00:00:00

  • Incremental Value of Cocktail 18F-FDG and 18F-NaF PET/CT Over 18F-FDG PET/CT Alone for Characterization of Skeletal Metastases in Breast Cancer.

    abstract:PURPOSE:The aim of this study was to evaluate the incremental value of cocktail F-FDG/F-NaF PET/CT over F-FDG PET/CT alone for detection of skeletal metastases in breast cancer patients. METHODS:Seventy patients with locally advanced/recurrent breast cancer were prospectively included. All patients underwent whole-bod...

    journal_title:Clinical nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/RLU.0000000000001615

    authors: Roop MJ,Singh B,Singh H,Watts A,Kohli PS,Mittal BR,Singh G

    更新日期:2017-05-01 00:00:00

  • 68Ga-Prostate-Specific Membrane Antigen Expression in Neurocysticercosis Lesions in a Patient With Prostate Carcinoma.

    abstract::Ga-prostate-specific membrane antigen (PSMA) ligand is a well-known tracer used in prostate cancer. Nevertheless, there are reports of unusual Ga-PSMA uptake in variety of benign lesions. We report a case of prostate cancer in which Ga-PSMA PET/CT revealed tracer avidity in the enhancing walls of cystic lesions in the...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001990

    authors: Vadi SK,Kumar R,Singh H,Singh SK,Mittal BR

    更新日期:2018-04-01 00:00:00

  • Bilateral cerebral mediofrontal hypoactivity in Tc-99m HMPAO SPECT imaging.

    abstract::Fifteen patients who had bilateral mediofrontal hypoactivity and 30 control subjects without this SPECT anomaly underwent Tc-99m HMPAO brain SPECT imaging. Bilateral mediofrontal hypoactivity was found in various neurologic disorders, including subcortical arteriosclerotic encephalopathy, lacunar state, chronic alcoho...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199410000-00006

    authors: Denays R,Tondeur M,Noël P,Ham HR

    更新日期:1994-10-01 00:00:00