Abstract:
:The gene causing adenomatous polyposis coli (APC) has recently been cloned. Three intragenic polymorphisms were reported to be detectable by single-strand conformation polymorphism analysis. Here, we describe an assay using polymerase-chain-reaction-based amplification and subsequent enzymatic digestion of genomic sequences to identify polymorphic sites at nucleotide positions 1458 and 5037 of the APC gene.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Kraus C,Ballhausen WGdoi
10.1007/BF02265305keywords:
subject
Has Abstractpub_date
1992-03-01 00:00:00pages
705-6issue
6eissn
0340-6717issn
1432-1203journal_volume
88pub_type
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