Abstract:
:An inv ins(7;2)(q21.2;q3105q24.2) was found to segregate through four generations of a family. Adjacent-1 segregation aneusomies were ascertained in five patients: three monosomics and two trisomics; and the corresponding syndromes were delineated. The comparative analysis between these and other previously described 2q aneusomic individuals led to the conclusion that a large cleft between first and second toes is a constant feature in monosomy 2q24----q31. No other trait could plausibly be mapped. Risks of 7.9 to 31.6% for aneusomic children and of 26.3% for abortion were estimated in the present family.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Moller M,García-Cruz D,Rivera H,Sánchez-Corona J,Cantú JMdoi
10.1007/BF00293878subject
Has Abstractpub_date
1984-01-01 00:00:00pages
77-86issue
1eissn
0340-6717issn
1432-1203journal_volume
68pub_type
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