Short alanine-based peptides may form 3(10)-helices and not alpha-helices in aqueous solution.

abstract：:Abscisic acid (ABA) is a vital phytohormone that regulates mainly stomatal aperture and seed development, but ABA receptors involved in these processes have yet to be determined. We previously identified from broad bean an ABA-binding protein (ABAR) potentially involved in stomatal signalling, the gene for which encod...

journal_title：Nature

authors： Shen YY,Wang XF,Wu FQ,Du SY,Cao Z,Shang Y,Wang XL,Peng CC,Yu XC,Zhu SY,Fan RC,Xu YH,Zhang DP

更新日期：2006-10-19 00:00:00

abstract：:The factor for inversion stimulation, FIS, is involved in several cellular processes, including site-specific recombination and transcriptional activation. In the reactions catalysed by the DNA invertases Gin, Hin and Cin, FIS stimulates recombination by binding to an enhancer sequence. Within the enhancer, two FIS di...

journal_title：Nature

authors： Kostrewa D,Granzin J,Koch C,Choe HW,Raghunathan S,Wolf W,Labahn J,Kahmann R,Saenger W

更新日期：1991-01-10 00:00:00

abstract：:Neurotransmitters modulate the activity of ion channels through a variety of second messengers, including cyclic AMP, cyclic GMP and the products of phosphatidylinositol breakdown. Little is known about how different transmitters acting through different second-messenger systems interact within a cell to regulate sing...

journal_title：Nature

authors： Belardetti F,Kandel ER,Siegelbaum SA

更新日期：1987-01-08 00:00:00

abstract：: ...

journal_title：Nature

authors： Silver A

更新日期：2019-01-01 00:00:00

abstract：:Potent marine neurotoxins known as brevetoxins are produced by the 'red tide' dinoflagellate Karenia brevis. They kill large numbers of fish and cause illness in humans who ingest toxic filter-feeding shellfish or inhale toxic aerosols. The toxins are also suspected of having been involved in events in which many mana...

journal_title：Nature

authors： Flewelling LJ,Naar JP,Abbott JP,Baden DG,Barros NB,Bossart GD,Bottein MY,Hammond DG,Haubold EM,Heil CA,Henry MS,Jacocks HM,Leighfield TA,Pierce RH,Pitchford TD,Rommel SA,Scott PS,Steidinger KA,Truby EW,Van Dolah FM

更新日期：2005-06-09 00:00:00

abstract：:An observer moving forwards through the environment experiences a radial pattern of image motion on each retina. Such patterns of optic flow are a potential source of information about the observer's rate of progress, direction of heading and time to reach objects that lie ahead. As the viewing distance changes there ...

journal_title：Nature

authors： Busettini C,Masson GS,Miles FA

更新日期：1997-12-04 00:00:00

abstract：:Real-time investigations of the rearrangement of bonds during chemical transformations require femtosecond temporal resolution, so that the atomic vibrations within the reacting molecules can be observed. Following the development of lasers capable of emitting ultrashort laser flashes on this timescale, chemical react...

journal_title：Nature

authors： Kobayashi T,Saito T,Ohtani H

更新日期：2001-11-29 00:00:00

abstract：:Bottom trawling is a non-selective commercial fishing technique whereby heavy nets and gear are pulled along the sea floor. The direct impact of this technique on fish populations and benthic communities has received much attention, but trawling can also modify the physical properties of seafloor sediments, water–sedi...

journal_title：Nature

authors： Puig P,Canals M,Company JB,Martín J,Amblas D,Lastras G,Palanques A

更新日期：2012-09-13 00:00:00

abstract：:Separation of eukaryotic sister chromatids during the cell cycle is timed by the spindle assembly checkpoint (SAC) and ultimately triggered when separase cleaves cohesion-mediating cohesin1-3. Silencing of the SAC during metaphase activates the ubiquitin ligase APC/C (anaphase-promoting complex, also known as the cycl...

journal_title：Nature

authors： Hellmuth S,Gómez-H L,Pendás AM,Stemmann O

更新日期：2020-04-01 00:00:00

abstract：:Most mitochondrial proteins are synthesized on cytoplasmic ribosomes and imported into mitochondria. The imported proteins are directed to one of four submitochondrial compartments--the outer mitochondrial membrane, the inner mitochondrial membrane, the intramembraneous space, or the matrix--where the protein then fun...

journal_title：Nature

authors： Bose HS,Lingappa VR,Miller WL

更新日期：2002-05-02 00:00:00

abstract：:Nuclear magic numbers correspond to fully occupied energy shells of protons or neutrons inside atomic nuclei. Doubly magic nuclei, with magic numbers for both protons and neutrons, are spherical and extremely rare across the nuclear landscape. Although the sequence of magic numbers is well established for stable nucle...

journal_title：Nature

authors： Taniuchi R,Santamaria C,Doornenbal P,Obertelli A,Yoneda K,Authelet G,Baba H,Calvet D,Château F,Corsi A,Delbart A,Gheller JM,Gillibert A,Holt JD,Isobe T,Lapoux V,Matsushita M,Menéndez J,Momiyama S,Motobayashi T,Nii

更新日期：2019-05-01 00:00:00

abstract：:Since the pioneering work of the Millers it has become clear that most chemical carcinogens require metabolism to reactive electrophiles and then exhibit their carcinogenic potential by reacting chemically with, and modifying, cellular macromolecules. At first modification of proteins was considered most likely to be ...

journal_title：Nature

authors： Allen JA,Coombs MM

更新日期：1980-09-18 00:00:00

abstract：:Transcription initiation factor TFIID is a multisubunit complex containing a TATA-box-binding factor (TFIID tau/TBP) and associated polypeptide factors (TAFs) with sizes ranging from M(r) approximately 20,000 to > 200,000. As a result of direct promoter interactions, TFIID nucleates the assembly of RNA polymerase II a...

journal_title：Nature

authors： Kokubo T,Gong DW,Wootton JC,Horikoshi M,Roeder RG,Nakatani Y

更新日期：1994-02-03 00:00:00

abstract：:NADH oxidation in the respiratory chain is coupled to ion translocation across the membrane to build up an electrochemical gradient. The sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR), a membrane protein complex widespread among pathogenic bacteria, consists of six subunits, NqrA, B, C, D, E and F. To ou...

journal_title：Nature

authors： Steuber J,Vohl G,Casutt MS,Vorburger T,Diederichs K,Fritz G

更新日期：2014-12-04 00:00:00

abstract：:Cocaine is believed to work by blocking the dopamine transporter (DAT) and thereby increasing the availability of free dopamine within the brain. Although this concept is central to current cocaine research and to treatment development, a direct relationship between DAT blockade and the subjective effects of cocaine h...

journal_title：Nature

authors： Volkow ND,Wang GJ,Fischman MW,Foltin RW,Fowler JS,Abumrad NN,Vitkun S,Logan J,Gatley SJ,Pappas N,Hitzemann R,Shea CE

更新日期：1997-04-24 00:00:00

abstract：:A hallmark of RNA silencing is a class of approximately 22-nucleotide RNAs that are processed from double-stranded RNA precursors by Dicer. Accurate processing by Dicer is crucial for the functionality of microRNAs (miRNAs). The current model posits that Dicer selects cleavage sites by measuring a set distance from th...

journal_title：Nature

authors： Park JE,Heo I,Tian Y,Simanshu DK,Chang H,Jee D,Patel DJ,Kim VN

更新日期：2011-07-13 00:00:00

abstract：:Large seasonal and hemispheric asymmetries in the martian climate system are generally ascribed to variations in solar heating associated with orbital eccentricity. As the orbital elements slowly change (over a period of >104 years), characteristics of the climate such as dustiness and the vigour of atmospheric circul...

journal_title：Nature

authors： Richardson MI,Wilson RJ

更新日期：2002-03-21 00:00:00

abstract：:The earliest cell fate decision in the mammalian embryo separates the extra-embryonic trophoblast lineage, which forms the fetal portion of the placenta, from the embryonic cell lineages. The body plan of the embryo proper is established only later at gastrulation, when the pluripotent epiblast gives rise to the germ ...

journal_title：Nature

authors： Russ AP,Wattler S,Colledge WH,Aparicio SA,Carlton MB,Pearce JJ,Barton SC,Surani MA,Ryan K,Nehls MC,Wilson V,Evans MJ

更新日期：2000-03-02 00:00:00

abstract：: ...

journal_title：Nature

authors： Masood E

更新日期：2018-11-01 00:00:00

abstract：:Framework cavities are the largest but least explored coral reef habitat. Previous dive studies of caverns, spaces below plate corals, rubble and artificial cavities suggest that cavity-dwelling (coelobite) filter-feeders are important in the trophodynamics of reefs. Quantitative community data are lacking, however, a...

journal_title：Nature

authors： Richter C,Wunsch M,Rasheed M,Kötter I,Badran MI

更新日期：2001-10-18 00:00:00

abstract：:Immune recognition of protein antigens relies on the combined interaction of multiple antibody loops, which provide a fairly large footprint and constrain the size and shape of protein surfaces that can be targeted. Single protein loops can mediate extremely high-affinity binding, but it is unclear whether such a mech...

journal_title：Nature

authors： Ekiert DC,Kashyap AK,Steel J,Rubrum A,Bhabha G,Khayat R,Lee JH,Dillon MA,O'Neil RE,Faynboym AM,Horowitz M,Horowitz L,Ward AB,Palese P,Webby R,Lerner RA,Bhatt RR,Wilson IA

更新日期：2012-09-27 00:00:00

abstract：:Interchromosomal gene conversion between alleles has been shown in yeast frequently to be associated with the recombination of flanking genetic markers. Although this also holds true for gene conversion between two alleles of the yeast mating-type (MAT) locus, initiated by the homothallic switching system, we find no ...

journal_title：Nature

authors： Klar AJ,Strathern JN

更新日期：1984-08-30 00:00:00

abstract：:Devices that convert information from one form into another according to a definite procedure are known as automata. One such hypothetical device is the universal Turing machine, which stimulated work leading to the development of modern computers. The Turing machine and its special cases, including finite automata, o...

journal_title：Nature

authors： Benenson Y,Paz-Elizur T,Adar R,Keinan E,Livneh Z,Shapiro E

更新日期：2001-11-22 00:00:00

abstract：:Dynamic access to genetic information is central to organismal development and environmental response. Consequently, genomic processes must be regulated by mechanisms that alter genome function relatively rapidly. Conventional chromatin immunoprecipitation (ChIP) experiments measure transcription factor occupancy, but...

journal_title：Nature

authors： Lickwar CR,Mueller F,Hanlon SE,McNally JG,Lieb JD

更新日期：2012-04-11 00:00:00

abstract：:The embryos and larvae of stalked crinoids, which are considered the most basal group of extant echinoderms, have not previously been described. In contrast, much is known about the development of the more accessible stalkless crinoids (feather stars), which are phylogenetically derived from stalked forms. Here we des...

journal_title：Nature

authors： Nakano H,Hibino T,Oji T,Hara Y,Amemiya S

更新日期：2003-01-09 00:00:00

abstract：:The nucleotides immediately surrounding intron/exon junctions of genes transcribed by RNA polymerase B can be derived from 'consensus' sequences for donor and acceptor splice sites by only a few base changes. Studies in vivo have underlined the importance of these junction nucleotides for splicing. In higher eukaryote...

journal_title：Nature

authors： Rautmann G,Breathnach R

更新日期：1985-05-30 00:00:00

abstract：:The RAD3 gene of Saccharomyces cerevisiae is required for excision repair of ultraviolet-damaged DNA and is essential for cell viability. The RAD3-encoded protein shares a high degree of homology with the human ERCC2(XPD) gene product. Mutations in XPD, besides causing the cancer-prone syndrome xeroderma pigmentosum, ...

journal_title：Nature

authors： Guzder SN,Qiu H,Sommers CH,Sung P,Prakash L,Prakash S

更新日期：1994-01-06 00:00:00

abstract：:Understanding the nature and origin of the asteroid population in Earth's vicinity (near-Earth asteroids, and its subset of potentially hazardous asteroids) is a matter of both scientific interest and practical importance. It is generally expected that the compositions of the asteroids that are most likely to hit Eart...

journal_title：Nature

authors： Vernazza P,Binzel RP,Thomas CA,DeMeo FE,Bus SJ,Rivkin AS,Tokunaga AT

更新日期：2008-08-14 00:00:00

abstract：:Interfacing a single photon with another quantum system is a key capability in modern quantum information science. It allows quantum states of matter, such as spin states of atoms, atomic ensembles or solids, to be prepared and manipulated by photon counting and, in particular, to be distributed over long distances. S...

journal_title：Nature

authors： Riedinger R,Hong S,Norte RA,Slater JA,Shang J,Krause AG,Anant V,Aspelmeyer M,Gröblacher S

更新日期：2016-02-18 00:00:00

abstract：:Graphene oxide membranes-partially oxidized, stacked sheets of graphene-can provide ultrathin, high-flux and energy-efficient membranes for precise ionic and molecular sieving in aqueous solution. These materials have shown potential in a variety of applications, including water desalination and purification, gas and ...

journal_title：Nature

authors： Chen L,Shi G,Shen J,Peng B,Zhang B,Wang Y,Bian F,Wang J,Li D,Qian Z,Xu G,Liu G,Zeng J,Zhang L,Yang Y,Zhou G,Wu M,Jin W,Li J,Fang H

更新日期：2017-10-19 00:00:00