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Anti-angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus.

Abstract：

:Fruiting bodies of Phellinus linteus were extracted with 70% ethanol at room temperature. The Phellinus linteus extract (PL) showed strong anti-angiogenic activity, which was detected using the chick embryo chorioallantoic membrane (CAM) assay. The in vitro antioxidant activities of PL were evaluated using two different bioassays. PL was comparable to Vitamin C in scavenging the stable free radical 1,1-diphenyl-2-picrylhyrazyl (DPPH). It also inhibited lipid peroxidation (LPO) in a concentration-dependent manner. These results suggest that antioxidant and anti-angiogenic activities of Phellinus linteus would be partly responsible for its anti-tumor effect.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Song YS,Kim SH,Sa JH,Jin C,Lim CJ,Park EH

doi

10.1016/s0378-8741(03)00178-8

keywords:

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

113-6

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378874103001788

journal_volume

88

pub_type

杂志文章

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