The impact of early testicular sperm extraction or cryopreservation on the outcome of intracytoplasmic sperm injection--a randomized controlled study.

Abstract:

PURPOSE:To compare the outcome of sperm extraction 24 h before ovum pickup and on the day of oocyte retrieval. METHODS:A controlled study was performed to compare the outcome of 90 sperm extractions and in vitro sperm injection cycles performed in 54 patients. RESULTS:Available fresh sperm for the sperm injection procedure and cryopreservation obtained on the day of ovum pickup were similar to sperm collected 1 day before (33.3% vs 39.4%, respectively). Fertilization rate obtained with fresh sperm was also similar (48.9% vs. 54%), respectively. Clinical pregnancy rate was 38% vs. 22% per embryo transfer, respectively (P = 0.235). When comparing an additional 24 cycles with cryopreservation of sperm retrieved on the day of ovum pickup, as well as a day previously, no significance was noted in the parameters. CONCLUSIONS:Sperm retrieved 24 h before oocyte retrieval and used as fresh or frozen-thawed for sperm injection are as effective as those used on the day of ovum pickup.

journal_name

J Assist Reprod Genet

authors

Dirnfeld L,Paz M,Yshai D,Calderon I,Lahav-Baratz S,Koifman M,Shiloh H,Abramovici H,Bider D

doi

10.1023/a:1024116326465

keywords:

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

205-9

issue

6

eissn

1058-0468

issn

1573-7330

journal_volume

20

pub_type

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