Abstract：
:Surgical resection remains the therapy of choice for the treatment of potentially curable gastrointestinal tract (GI) malignancies. Many of these tumors are incurable at the time of diagnosis and therapy should be directed towards palliation with the intent of minimizing pain, bleeding, obstruction, and potential morbidity. Endoscopic laser therapy is uniquely applicable for the palliation of GI tumors and in selective instances may be appropriate for the treatment of early lesions. Eighty-six patients with GI malignancy have been treated at our institution since 1985. Thirty-one patients had advanced upper GI lesions (esophagus: 26, gastric: 3, duodenal: 1, and pancreatic: 1) and 55 patients had lower GI tumors (colon: 37 and rectal: 18). Pre-resectional recanalization for obstructing colorectal carcinomas obviating initial operative diversion was performed in 31 (56%) of 55 patients. Twenty-four patients had palliative laser therapy (obstruction: 17 and hemorrhage: 7) with resolution of their symptoms. There was 1 laser related perforation in the pre-resectional group and the overall complication rate was 1.2%. Endoscopic Nd:YAG and currently photodynamic laser therapy for GI tumors has proven to be an effective mode of therapy for advanced GI neoplasms with minimal morbidity. The utility of photodynamic therapy for the treatment of early stage esophageal and gastric cancers remains controversial.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Eckhauser MLdoi
10.1007/BF02067061keywords:
subject
Has Abstractpub_date
1992-11-01 00:00:00pages
1054-9issue
6eissn
0364-2313issn
1432-2323journal_volume
16pub_type
杂志文章abstract：BACKGROUND:This study reviews the 15 year program of our Department of Pediatric Surgery for the treatment and follow-up of children born with a cleft in Benin and Togo. METHODS:We analyzed files of children born in Africa with a cleft. They were referred to us through a nongovernmental organization (NGO) between 1993...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1607-z
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:The majority of small bowel obstructions (SBO) are the result of adhesions caused by a previous abdominal operation. On rare occasions, adhesional SBO occurs in the absence of such an operation. Our objective was to describe the management, findings, and outcomes of unexplained adhesional SBO (UA-SBO) and ex...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0200-6
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:The present study was designed to evaluate the relationship between preoperative Toll-like receptor (TLR) expression in peripheral blood monocytes (PBMC) and the postoperative inflammatory cytokine secretion from PBMC, as well as the postoperative infectious complications in patients with gastrointestinal ca...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0839-z
更新日期：2011-02-01 00:00:00
abstract：:The moral dilemmas faced by surgeons worldwide who treat patients infected with the human immunodeficiency virus (HIV) can be viewed against the background of experience in sub-Saharan countries, where the community prevalence is in excess of 25% (90% of hospital inpatients). When seeking consent for an HIV test befor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7101-x
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Although the low central venous pressure (LCVP) technique is used to decrease blood loss during liver resection, its efficacy and safety during transplant procedures are still debatable. Our study aimed to assess the effects of this technique and its clinical safety for recipients undergoing liver transplant...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-010-0544-y
更新日期：2010-08-01 00:00:00
abstract：:Secretin is a stimulator of both endocrine and exocrine secretions of the pancreas, and we aimed to evaluate its effects on splanchnic blood flow in rats with a microsphere technique. Anesthetized rats were infused with secretin (0.5 or 2.0 micrograms/kg body weight/hr) for 10 minutes. Some animals were normoglycemic,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0037-0
更新日期：2001-07-01 00:00:00
abstract：BACKGROUND:Transient postthyroidectomy hypocalcemia occurs in up to 30% of patients. We evaluated the effect of vitamin D deficiency on postthyroidectomy hypocalcemia. METHODS:Data were collected prospectively between January 2006 and March 2009. A total of 166 consecutive total thyroidectomies were analyzed regarding...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0872-y
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Esophageal achalasia is characterized by the absence of esophageal peristalsis and by a dysfunctional lower esophageal sphincter (LES). Descriptions of clinical, radiological, and manometric findings in patients with achalasia usually have been based on small numbers of patients. This study was designed to d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9656-z
更新日期：2008-09-01 00:00:00
abstract：:The acid-base balance from the postoperative day (POD) 1 to POD 3 after cirrhotic liver resection was investigated in relation to operative outcome by conducting a retrospective study on the changes in arterial ketone body ratio (AKBR), which reflects the hepatic mitochondrial redox state, and arterial blood gas analy...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01655722
更新日期：1993-01-01 00:00:00
abstract：:Transsphenoidal pituitary surgery has radically modified the management of pituitary-dependent hypercortisolism (Cushing's disease). Bilateral adrenalectomy may, however, represent the ultimate treatment in some cases of hypercortisolism. In the present study we report our experience of bilateral adrenalectomy in 82 p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900118
更新日期：1996-09-01 00:00:00
abstract：:Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6264-1
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Intra-abdominal adhesions constitute between 49% and 74% of the causes of small bowel obstruction. Traditionally, laparotomy and open adhesiolysis have been the treatment for patients who have failed conservative measures or when clinical and physiologic derangements suggest toxemia and/or ischemia. With the...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7778-0
更新日期：2006-04-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux disease is common in Western societies, although the prevalence of reflux symptoms in the community is not well described. In this study we determined the prevalence of symptoms of gastroesophageal reflux and other "esophageal" symptoms, and the consumption of medication for reflux ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9780-9
更新日期：2009-01-01 00:00:00
abstract：:The present article summarizes scientific observations of the endocrine pancreas anatomy and physiology into a unifying hypothesis. The data were generated over the years by surgical fellows using human and rat isolated perfused pancreas models and in vivo islet microcirculation models. The endocrine pancreas secretes...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680020339
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:The retained knife blade is an unusual and spectacular injury. The aim of this study was to review our experience with the management of such injuries. METHODS:A retrospective chart review of patients with retained knife blades treated at Groote Schuur Hospital Trauma Centre from January 1996 to December 20...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0514-4
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:The postoperative functional advantages of a proximal gastrectomy over a total gastrectomy remain debatable. The aim of this study was to evaluate the functional outcomes of a proximal gastrectomy with jejunal interposition (PG-JI), compared with those for a total gastrectomy with Roux-en-Y esophagojejunosto...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3180-8
更新日期：2015-11-01 00:00:00
abstract：:Histologically differentiated adenocarcinoma satisfies one of the criteria for limited surgery for mucosal carcinoma of the stomach: however, the histology of the endoscopic biopsy specimen is often different from that of the resected specimen. The medical records of 1018 early gastric carcinomas were retrospectively ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900483
更新日期：1998-08-01 00:00:00
abstract：BACKGROUND:Although multidetector-row computed tomography (MDCT) before biliary drainage is useful for the assessment of the resectability of perihilar cholangiocarcinoma (PHC), the impact of biliary drainage on MDCT images before surgical resection for PHC has been poorly studied, and its possible consequences for R0 ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4654-2
更新日期：2018-11-01 00:00:00
abstract：:Multiple organ failure (MOF) is considered to be the leading cause of death after severe trauma. Although there is extensive literature on MOF, little is known about the pattern, sequence, and onset of this clinical syndrome. The first goal of this clinical study was to define MOF; the second was to assess the typical...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900067
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:The World Health Organization has a standardized tool to assess surgical capacity in low- and middle-income countries (LMICs), but it is often resource- and time-intensive. There currently exists no simple, evidence-based measure of surgical capacity in these settings. The proportion of cesarean deliveries i...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1794-7
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Distal splenorenal shunt and coronary caval shunt are commonly used for selective decompression of esophagogastric varices, but they may not solve severe hypersplenism and their application may be hampered by the presence of splenic venous thrombosis or a left gastric vein (LGV) situated deeply behind the pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4796-2
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Laparoscopic hepatectomy (LH) is established as a safe and feasible treatment option for liver tumors. However, whether the adoption of laparoscopic approach for malignant tumors, such as hepatocellular carcinoma (HCC), will compromise the long-term result is still unknown. This study was designed to evaluat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1212-6
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis, as a majority of patients present with advanced disease. Current adjuvant strategies for metastatic patients include mitotane or other cytotoxic agents and carry a significant morbidity as well as a low (<10 %) 5-year sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2532-0
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:It has been suggested that gender and age could be factors that influence the likelihood of success following antireflux surgery, and our anecdotal impression has been that the outcome following Nissen fundoplication in older women is often disappointing. If correct, characterization of the extent of any dif...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0216-y
更新日期：2009-12-01 00:00:00
abstract：:The role of liver transplantation in malignancy has been discussed, but controversially, over the past two decades. This is particularly true for hepatic metastases from neuroendocrine tumors, which have a wide variety of primary tumor localizations, morphologic types, functional activities, and clinical presentations...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0016-5
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Every day thousands of surgeons and patients negotiate their way through the complex process of decision-making about operative treatments. We conducted a series of qualitative studies, asking patients and surgeons to describe their experience and beliefs about informed decision-making and consent. This stud...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0021-7
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:Better prognostic markers are needed for pancreatic endocrine tumors. Survivin is an apoptosis inhibitor that is suggested to have a negative prognostic impact in several tumor types. Contradictory data exist, especially regarding the significance of a nuclear versus cytoplasmic location of survivin. The pro...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1345-7
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Currently, most patients undergoing laparoscopic cholecystectomy (LC) in Switzerland are inpatients for 2-3 days. Due to a lack of available hospital beds, we asked whether day-case surgery would be an option for patients in central Switzerland. The questions of acceptability of outpatient LC and factors con...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4098-0
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Due to advances in operative methods and perioperative care, mortality and morbidity following major hepatic resection have decreased substantially, making long-term quality of life (QoL) an increasingly prominent issue. We evaluated whether postoperative diagnosis was associated with long-term QoL and healt...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0032-4
更新日期：2009-07-01 00:00:00
abstract：:From January, 1975 to December, 1987, 241 patients with rectal cancer underwent pre-operative irradiation and surgical resection. The radiation was delivered with 25 MeV photons, 5 days per week by 2.4 grays fractions up to a total dose of 36 grays. Surgery was curative in 195 patients; 57% had abdomino-perineal resec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067122
更新日期：1992-01-01 00:00:00
