Increased expression of phosphorylated c-Jun amino-terminal kinase and phosphorylated c-Jun in human cerebral aneurysms: role of the c-Jun amino-terminal kinase/c-Jun pathway in apoptosis of vascular walls.

abstract：OBJECTIVE:To examine the incidence and possible determinants of impaired vascular reserve in arteriovenous malformation (AVM)-affected brain, before and after surgery. METHODS:In a prospective study of 30 patients, the regional cerebrovascular reserve capacity (rCRC) and the vasodilated regional cerebral blood flow (r...

journal_title：Neurosurgery

authors： Van Roost D,Schramm J

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Fever is associated with worse outcome after subarachnoid hemorrhage, but there are few prospective data to quantify this relationship. METHODS:We prospectively enrolled consecutive aneurysmal or cryptogenic subarachnoid hemorrhage patients and recorded the highest core temperature each calendar day for Day ...

journal_title：Neurosurgery

authors： Naidech AM,Bendok BR,Bernstein RA,Alberts MJ,Batjer HH,Watts CM,Bleck TP

更新日期：2008-08-01 00:00:00

abstract：:We report five patients with anterior choroidal artery syndrome after surgery for internal carotid artery aneurysms. All patients suffered hemiparesis, and hemisensory loss and homonymous hemianopsia were identified in 2 patients. The characteristic triad of the syndrome was recognized in only 1 patient. Dominant and ...

journal_title：Neurosurgery

authors： Suzuki H,Fujita K,Ehara K,Tamaki N

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:The results of the surgical treatment of osteomyelitis with expandable titanium cages and either allograft or autograft are presented. METHODS:Thirty-six patients with vertebral osteomyelitis are presented. There were 7 cervical, 17 thoracic, 4 thoracolumbar (involving T12-L1), 5 lumbar, and 3 lumbosacral (i...

journal_title：Neurosurgery

authors： Lu DC,Wang V,Chou D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Rathke cleft cysts (RCCs), benign remnants of the Rathke pouch typically arising in the sella, sometimes have suprasellar extension. Purely suprasellar RCCs are rarely reported. OBJECTIVE:To compare the presentations, surgical outcomes, and pathology of purely suprasellar RCCs and sellar-based RCCs. METHOD...

journal_title：Neurosurgery

authors： Potts MB,Jahangiri A,Lamborn KR,Blevins LS,Kunwar S,Aghi MK

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to investigate the use of proton magnetic resonance spectroscopic imaging as a prognostic indicator in gamma knife radiosurgery of recurrent gliomas. METHODS:Thirty-six patients with recurrent gliomas were studied with proton magnetic resonance spectroscopic imaging at the time of ...

journal_title：Neurosurgery

authors： Graves EE,Nelson SJ,Vigneron DB,Chin C,Verhey L,McDermott M,Larson D,Sneed PK,Chang S,Prados MD,Lamborn K,Dillon WP

更新日期：2000-02-01 00:00:00

abstract：:Three cases of primary infectious spondylitis, two caused by Staphylococcus aureus and one by tuberculosis, were diagnosed using the method previously described for automated percutaneous discectomy. All three patients, in whom biopsy using fine needle techniques previously was unsuccessful, had positive cultures from...

journal_title：Neurosurgery

authors： Onik G,Shang YL,Maroon J,Eichenblat M,Mercer D,Bailes JE

更新日期：1990-02-01 00:00:00

abstract：:Eleven cases of cerebral cavernous angiomas (cavernomas) were observed within a period of 3 years. Two patients presented with cerebral hemorrhage, five with epilepsy, three each with a progressive focal neurological deficit, and one with papilledema. The unruptured lesions had a heterogeneous density on computed tomo...

journal_title：Neurosurgery

authors： Steiger HJ,Markwalder TM,Reulen HJ

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Median nerve neuropathy can be clinically devastating to a patient. It can be caused by compression of the median nerve anywhere along its course. We present the case of delayed median nerve neuropathy after the placement of a vascular graft in the arm. CLINICAL PRESENTATION:An arm shunt was p...

journal_title：Neurosurgery

authors： Goldstein LJ,Helfend LK,Kordestani RK

更新日期：2002-02-01 00:00:00

abstract：:An original stereotactic radiosurgical approach coupling a) Talairach's stereotactic methodology, b) a specially devised mechanical system, and c) a linear accelerator is detailed. The authors present their preliminary results on 66 patients with nonsurgical intracranial arteriovenous malformations. The doses delivere...

journal_title：Neurosurgery

authors： Betti OO,Munari C,Rosler R

更新日期：1989-03-01 00:00:00

abstract：:Syringomyelia, once regarded as a degenerative disease of adults, is now recognized to be a disorder usually associated with the Chiari malformation and occurring in patients of all ages. We have reviewed 47 patients with syringomyelia treated on the Neurosurgical Service at the Hospital for Sick Children during the y...

journal_title：Neurosurgery

authors： Hoffman HJ,Neill J,Crone KR,Hendrick EB,Humphreys RP

更新日期：1987-09-01 00:00:00

abstract：:A retrospective analysis of 50 consecutive patients treated with chemonucleolysis and 50 treated with microlumbar discectomy was carried out. Similar clinical criteria for the diagnosis of "virgin" herniated lumbar discs were used. All patients had low back or radicular pain unrelieved by a minimum of 4 weeks of conse...

journal_title：Neurosurgery

authors： Maroon JC,Abla A

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:A critical concept in brachial plexus reconstruction is the accurate assessment of functional outcomes. The current standard for motor outcome assessment is clinician-elicited, outpatient clinic-based, serial evaluation of range of motion and muscle power. However, discrepancies exist between such clinical m...

journal_title：Neurosurgery

authors： Smith BW,Chang KW,Saake SJ,Yang LJ,Chung KC,Brown SH

更新日期：2019-09-01 00:00:00

abstract：:This study examines the pathophysiology of stroke secondary to focal cerebral ischemia. The interaction of arachidonic acid metabolites and polyamines, a class of ubiquitous ornithine-derived molecules with important membrane effects on edema, Ca++-dependent endocytosis, platelet function, and prostaglandin (PG) forma...

journal_title：Neurosurgery

authors： Dempsey RJ,Roy MW,Meyer K,Tai HH,Olson JW

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Stereotactic laser ablation offers an advantage over open surgical procedures for treatment of epileptic foci, tumors, and other brain pathology. Robot-assisted stereotactic laser ablation could offer an accurate, efficient, minimally invasive, and safe method for placement of an ablation catheter into the t...

journal_title：Neurosurgery

authors： Gonzalez-Martinez J,Vadera S,Mullin J,Enatsu R,Alexopoulos AV,Patwardhan R,Bingaman W,Najm I

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Spinal cord dose limits are critically important for the safe practice of spine stereotactic body radiotherapy (SBRT). However, the effect of inherent spinal cord motion on cord dose in SBRT is unknown. OBJECTIVE:To assess the effects of cord motion on spinal cord dose in SBRT. METHODS:Dynamic balanced fas...

journal_title：Neurosurgery

authors： Oztek MA,Mayr NA,Mossa-Basha M,Nyflot M,Sponseller PA,Wu W,Hofstetter CP,Saigal R,Bowen SR,Hippe DS,Yuh WTC,Stewart RD,Lo SS

更新日期：2020-06-04 00:00:00

abstract：BACKGROUND:Functional neuronavigation with intraoperative 3-dimensional (3D) ultrasound may facilitate safer brain lesion resections than conventional neuronavigation. OBJECTIVE:In this study, functional magnetic resonance imaging (fMRI) and diffusion tensor tractography (DTT) were used to map eloquent areas. We asses...

journal_title：Neurosurgery

authors： Berntsen EM,Gulati S,Solheim O,Kvistad KA,Torp SH,Selbekk T,Unsgård G,Håberg AK

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:The natural history of pineal region germ cell tumors (GCTs) is not well known. We report a rare case of a pineal region GCT showing rapid enlargement within 2 months, after 7 years with no growth. CLINICAL PRESENTATION:A boy presented with gonadotropin-independent precocious puberty at 6 yea...

journal_title：Neurosurgery

authors： Jinguji S,Fukuda M,Nagasaki K,Fujii Y

更新日期：2013-04-01 00:00:00

abstract：:An 8-year-old boy presented in coma and was found to have a massive posterior fossa hemorrhage on computed tomographic scan. Autopsy disclosed a large cerebellar hematoma within a mixed glioma containing both juvenile pilocytic astrocytoma and oligodendroglioma. It is postulated that the hemorrhage originated from the...

journal_title：Neurosurgery

authors： Specht CS,Pinto-Lord C,Smith TW,DeGirolami U,Suran E,Marshall PC,Davidson RI

更新日期：1986-08-01 00:00:00

abstract：:The intrathecal (i.t.) administration of morphine inhibits nociceptive motor responses and activity in ascending axons evoked by stimulation of nociceptive afferent nerve fibers (nociceptive sensory response) in the rat. The i.t. administration of cholecystokinin octapeptide and ceruletide inhibits nociceptive motor r...

journal_title：Neurosurgery

authors： Jurna I

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, efficacy, and utility of a novel surgical strategy consisting of multiple (more than two) operative stages performed during the same hospital admission with subdural grid and strip electrodes in selected pediatric extratemporal epilepsy. METHODS:Subdural grid and strip electrodes were...

journal_title：Neurosurgery

authors： Bauman JA,Feoli E,Romanelli P,Doyle WK,Devinsky O,Weiner HL

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Relatively little attention has been paid to emotional outcome after subarachnoid hemorrhage (SAH). This study assessed levels of anxiety and depression among SAH survivors and related these to clinical indices. METHODS:Seventy SAH patients from a consecutive series of neurosurgical admissions participated i...

journal_title：Neurosurgery

authors： Morris PG,Wilson JT,Dunn L

更新日期：2004-01-01 00:00:00

abstract：:During radiofrequency (RF) heating of trigeminal rootlets, we regularly measured blood pressure rises to 250 to 300 mm Hg, confirming two previous reports. We also found abnormally increased bleeding times in 12% of 127 patients awaiting operation for trigeminal neuralgia. These two facts probably explain 6 fatalities...

journal_title：Neurosurgery

authors： Sweet WH,Poletti CE,Roberts JT

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of embolization for spinal dural arteriovenous fistulae (SDAVF). METHODS:We reviewed 49 cases of SDAVF treated by embolization. An acrylic material was used in all except two cases. Variable stiffness microcatheters were used in 38 cases. RESULTS:"Adequate" initial treatment was per...

journal_title：Neurosurgery

authors： Niimi Y,Berenstein A,Setton A,Neophytides A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Cerebral vasospasm is an independent predictor of poor outcome after subarachnoid hemorrhage (SAH). The nitric oxide-cyclic guanosine monophosphate (NO-cGMP) vasodilatory pathway is strongly implicated in its pathophysiology. Preliminary studies suggest that phosphodiesterase 5 (PDE5), an enzyme that degrade...

journal_title：Neurosurgery

authors： Han BH,Vellimana AK,Zhou ML,Milner E,Zipfel GJ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Medical students applying for neurosurgery residency positions almost all aspire to become academic neurosurgeons. However, most graduates of neurosurgery residency programs ultimately follow careers in private practice. We hypothesized that there might be factors in a resident's application, interviews, or p...

journal_title：Neurosurgery

authors： Lawton MT,Narvid J,Quiñones-Hinojosa A

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Tentorial dural arteriovenous malformations (DAVMs) are uncommon lesions associated with an aggressive natural history. Controversy exists regarding their optimal treatment. We present a single-institution series of tentorial DAVMs treated during a 12-year period, address the current controversies, and presen...

journal_title：Neurosurgery

authors： Tomak PR,Cloft HJ,Kaga A,Cawley CM,Dion J,Barrow DL

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To investigate the potential of novel magnetic resonance (MR) angiographic techniques for the assessment of cerebral arteriovenous malformations. METHODS:Forty patients who were about to undergo stereotactic radiosurgery were prospectively recruited. Three-dimensional, sliding-slab interleaved ky (SLINKY), t...

journal_title：Neurosurgery

authors： Warren DJ,Hoggard N,Walton L,Radatz MW,Kemeny AA,Forster DM,Wilkinson ID,Griffiths PD

更新日期：2007-07-01 00:00:00

abstract：:Spontaneous intracranial hemorrhage (ICH) is a rare but devastating complication in patients with chronic immune thrombocytopenic purpura (ITP). We report four patients with chronic ITP unresponsive to steroid treatment who developed ICH. One patient had systemic lupus erythematosus; in another patient, the ICH origin...

journal_title：Neurosurgery

authors： Brenner B,Guilburd JN,Tatarsky I,Doron Y,Goldsher D

更新日期：1988-04-01 00:00:00

abstract：:This study investigated the spinal evoked response to focal electrical stimulation of the sensorimotor cortex in 32 rats. The results demonstrate a long-latency response (beginning at 8 milliseconds) elicited by electrical stimulation, which is distinct from the short-latency motor evoked potential previously reported...

journal_title：Neurosurgery

authors： Ryder J,Zappulla R,Nieves J

更新日期：1991-04-01 00:00:00