The use of allograft or autograft and expandable titanium cages for the treatment of vertebral osteomyelitis.

Abstract:

OBJECTIVE:The results of the surgical treatment of osteomyelitis with expandable titanium cages and either allograft or autograft are presented. METHODS:Thirty-six patients with vertebral osteomyelitis are presented. There were 7 cervical, 17 thoracic, 4 thoracolumbar (involving T12-L1), 5 lumbar, and 3 lumbosacral (involving L5-S1) lesions. The most frequently identified organisms were Staphylococcus aureus, Mycobacterium tuberculosis, and Coccidioides immitis. Imaging studies included x-rays, computed tomographic scans, and magnetic resonance imaging scans. All patients were treated with corpectomies and expandable cage reconstruction. Fusion was performed with rib autograft, iliac crest autograft, or allograft. Most patients who had an anterior approach also underwent posterior instrumentation, whereas a few had anterior instrumentation only. Four patients underwent a posterior approach (transpedicular corpectomy) only. RESULTS:The median follow-up period was 21 months. There were no implant failures. Two recurrences of infection were noted: 1 case involved allograft, and the other involved autograft. At follow-up, neurological deficits improved in all patients, and 81% of patients were pain-free. CONCLUSION:This study suggests that the treatment of vertebral column osteomyelitis can be performed with expandable titanium cages, and allograft does not appear to increase the rate of recurrence, as compared with autograft.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Lu DC,Wang V,Chou D

doi

10.1227/01.NEU.0000336332.11957.0B

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

122-9; discussion 129-30

issue

1

eissn

0148-396X

issn

1524-4040

pii

00006123-200901000-00015

journal_volume

64

pub_type

杂志文章
  • Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors.

    abstract:BACKGROUND:Achieving seizure control in patients with low-grade temporal lobe gliomas or glioneuronal tumors remains highly underappreciated, because seizures are the most frequent presenting symptom and significantly impact patient quality-of-life. OBJECTIVE:To assess how the extent of temporal lobe resection influen...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/NEU.0b013e31823c3a30

    authors: Englot DJ,Han SJ,Berger MS,Barbaro NM,Chang EF

    更新日期:2012-04-01 00:00:00

  • Clinical evaluation and follow-up outcome of diffusion tensor imaging-based functional neuronavigation: a prospective, controlled study in patients with gliomas involving pyramidal tracts.

    abstract:OBJECTIVE:To evaluate diffusion tensor imaging (DTI)-based functional neuronavigation in surgery of cerebral gliomas with pyramidal tract (PT) involvement with respect to both perioperative assessment and follow-up outcome. METHODS:A prospective, randomized controlled study was conducted between 2001 and 2005. A conse...

    journal_title:Neurosurgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1227/01.neu.0000303189.80049.ab

    authors: Wu JS,Zhou LF,Tang WJ,Mao Y,Hu J,Song YY,Hong XN,Du GH

    更新日期:2007-11-01 00:00:00

  • The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury: Correlations With Clinical and Imaging Findings.

    abstract:BACKGROUND:Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) are promising biomarkers of traumatic brain injury (TBI). OBJECTIVE:We investigated the relation of the GFAP and UCH-L1 levels to the severity of TBI during the first week after injury. METHODS:Plasma UCH-L1 and GFAP were...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000001226

    authors: Posti JP,Takala RS,Runtti H,Newcombe VF,Outtrim J,Katila AJ,Frantzén J,Ala-Seppälä H,Coles JP,Hossain MI,Kyllönen A,Maanpää HR,Tallus J,Hutchinson PJ,van Gils M,Menon DK,Tenovuo O

    更新日期:2016-09-01 00:00:00

  • Iliac screw fixation using computer-assisted computer tomographic image guidance: technical note.

    abstract:BACKGROUND:Iliac screw fixation is a powerful tool used by spine surgeons to achieve fusion across the lumbosacral junction for a number of indications, including deformity, tumor, and pseudarthrosis. Complications associated with screw placement are related to blind trajectory selection and excessive soft tissue disse...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318230517a

    authors: Shin JH,Hoh DJ,Kalfas IH

    更新日期:2012-03-01 00:00:00

  • Blister Aneurysms of the Internal Carotid Artery: Microsurgical Results and Management Strategy.

    abstract:Background:Blister aneurysms of the supraclinoid internal carotid artery (ICA) are challenging lesions with high intraoperative rupture rates and significant morbidity. An optimal treatment strategy for these aneurysms has not been established. Objective:To analyze treatment strategy, operative techniques, and outcome...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000001259

    authors: Owen CM,Montemurro N,Lawton MT

    更新日期:2017-02-01 00:00:00

  • Evidence for a central pathway in the cerebrovascular effects of spinal cord stimulation.

    abstract:OBJECTIVE:Cervical spinal cord stimulation (SCS) augments cerebral blood flow (CBF) in a number of animal models. The mechanisms underlying the cerebrovascular effects of SCS are not yet well delineated. In this study, we analyzed two alternative pathways in CBF alterations induced by SCS in rats, one involving direct ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000126949.28912.71

    authors: Patel S,Huang DL,Sagher O

    更新日期:2004-07-01 00:00:00

  • Feasibility, safety, and periprocedural complications associated with endovascular treatment of selected ruptured aneurysms under conscious sedation and local anesthesia.

    abstract:BACKGROUND:Endovascular coil embolization of ruptured aneurysms is performed under general anesthesia at most centers for perceived improved image quality and patient safety. OBJECTIVE:To report the feasibility of and outcomes associated with endovascular treatment of subarachnoid hemorrhage (SAH) patients with ruptur...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31827b9183

    authors: Kan P,Jahshan S,Yashar P,Orion D,Webb S,Siddiqui AH,Hopkins LN,Levy EI

    更新日期:2013-02-01 00:00:00

  • Colored silicone injection for use in neurosurgical dissections: anatomic technical note.

    abstract:OBJECTIVE:The dissection of cadaveric specimens is very important for a more sophisticated understanding of neurosurgical anatomic features and approaches. Teaching known approaches to residents or learning new approaches is best performed in a cadaveric laboratory. The utility of neurosurgical cadaveric dissections ca...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199911000-00058

    authors: Sanan A,Abdel Aziz KM,Janjua RM,van Loveren HR,Keller JT

    更新日期:1999-11-01 00:00:00

  • Comparison of intrathecal administration of urokinase and tissue plasminogen activator on subarachnoid clot and chronic vasospasm in a primate model.

    abstract::Safety and efficacy of the thrombolytic agent urokinase (URO) in the elimination of subarachnoid clot and prevention of chronic vasospasm was compared with tissue-type plasminogen activator (rt-PA) in a blind, randomized placebo-controlled trial. Twenty monkeys were randomly assigned to one of five groups of four. Eac...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199310000-00020

    authors: Hariton GB,Findlay JM,Weir BK,Kasuya H,Grace MG,Mielke BW

    更新日期:1993-10-01 00:00:00

  • The neurosurgical workforce in North America: a critical review of gender issues.

    abstract:OBJECTIVE:The role of women in Western society has changed dramatically in the past several decades. Despite this, many gender disparities still exist for professionals in the health care sector. In neurosurgery, a disproportionately small percentage of the workforce in the United States and Canada is female. These fig...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/01.NEU.0000232671.44297.DF

    authors: Woodrow SI,Gilmer-Hill H,Rutka JT

    更新日期:2006-10-01 00:00:00

  • Vietnam, 1968-1969: a place and a year like no other.

    abstract::THE VIETNAM WAR touched a generation of Americans with its human tragedy, sacrifice, and strife. In terms of casualties, it was the fourth most costly war in American history. However, despite a monumental military effort and modern technology, the war was lost as support from the American public and its elected offic...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1227/01.neu.0000053179.51319.d0

    authors: Kelly PJ

    更新日期:2003-04-01 00:00:00

  • Hemodynamic evaluation of basilar and vertebral artery angioplasty.

    abstract:OBJECTIVE:The postangioplasty evaluation of a stenotic vessel is often conducted by studying serial angiograms to determine the anatomic reduction in stenosis. In flow-limiting stenosis, the hemodynamic change that accompanies these anatomic changes is of great importance in evaluating the success of the angioplasty. T...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Guppy KH,Charbel FT,Corsten LA,Zhao M,Debrun G

    更新日期:2002-08-01 00:00:00

  • Analysis of Anterior Cervical Discectomy and Fusion Healthcare Costs via the Value-Driven Outcomes Tool.

    abstract:BACKGROUND:Examining the costs of single- and multilevel anterior cervical discectomy and fusion (ACDF) is important for the identification of cost drivers and potentially reducing patient costs. A novel tool at our institution provides direct costs for the identification of potential drivers. OBJECTIVE:To assess peri...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyy126

    authors: Reese JC,Karsy M,Twitchell S,Bisson EF

    更新日期:2019-02-01 00:00:00

  • Syndrome of inappropriate antidiuretic hormone secretion after spontaneous subarachnoid hemorrhage: a reversible cause of clinical deterioration.

    abstract::The syndrome of inappropriate antidiuretic hormone secretion (SIADH) developed approximately 7 days after a spontaneous subarachnoid hemorrhage in a 63-year-old woman with an anterior cerebral artery aneurysm. The hyponatremia associated with this syndrome resulted in a deterioration of the patient's clinical conditio...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197811000-00016

    authors: Wise BL

    更新日期:1978-11-01 00:00:00

  • Choroid plexus papillomas: an immunohistochemical study with particular reference to the coexpression of prealbumin.

    abstract::Immunocytochemical characterization of choroid plexus neoplasms was performed in seven cases, five being of benign choroid plexus papilloma (CPP) and the other two of malignant choroid plexus papilloma (choroid plexus carcinoma CPC). Immunohistochemical examination was performed with antibodies to glial fibrillary aci...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198809000-00021

    authors: Matsushima T,Inoue T,Takeshita I,Fukui M,Iwaki T,Kitamoto T

    更新日期:1988-09-01 00:00:00

  • O-desulfated heparin improves outcome after rat cerebral ischemia/reperfusion injury.

    abstract:OBJECTIVE:Inflammatory cascades play a significant role in progressive neurological injury after transient cerebral ischemia. It has been demonstrated that heparin, a potent anticoagulant, also possesses anti-inflammatory properties that diminish postreperfusion damage after stroke. However, the potential for heparin t...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000306109.55174.e6

    authors: Mocco J,Shelton CE,Sergot P,Ducruet AF,Komotar RJ,Otten ML,Sosunov SA,Macarthur RB,Kennedy TP,Connolly ES Jr

    更新日期:2007-12-01 00:00:00

  • Spinal cord compression: a complication of silicone-coated Dacron dural grafts. Report of two cases.

    abstract::Two case reports of compression of the cervical spinal cord associated with silicone-coated Dacron dural grafts are presented. In both cases, the cervical spinal cord was distorted and compressed by an intense tissue reaction that encapsulated the synthetic graft. At least two factors are thought to play a role in pre...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198901000-00022

    authors: Gomez H,Little JR

    更新日期:1989-01-01 00:00:00

  • Transdural approach to the anterior spinal canal in patients with cervical spondylotic myelopathy and superimposed central soft disc herniation.

    abstract::We present seven patients with multilevel cervical spondylotic myelopathy and superimposed midline soft disc herniation who were treated by decompressive laminectomies of the spondylotic segments followed by transdural excision of the anteriorly located disc extrusion. There was no perioperative neurological morbidity...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199404000-00010

    authors: Fox MW,Onofrio BM

    更新日期:1994-04-01 00:00:00

  • Risk factors for subarachnoid hemorrhage.

    abstract:OBJECTIVE:Cigarette smoking has been demonstrated to increase the risk of subarachnoid hemorrhage (SAH). Whether cessation of smoking decreases this risk remains unclear. We performed a case-control study to examine the effect of smoking and other known risk factors for cerebrovascular disease on the risk of SAH. METH...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200109000-00014

    authors: Qureshi AI,Suri MF,Yahia AM,Suarez JI,Guterman LR,Hopkins LN,Tamargo RJ

    更新日期:2001-09-01 00:00:00

  • Neurofibromatosis and optic glioma: clinical and morphological correlations.

    abstract::Although an association between optic glioma and neurofibromatosis is well recognized, there has been no previous analysis of cases relating the locus of tumor to the presence or absence of von Recklinghausen's disease. This paper presents the results of such an analysis as well as a description of the comparative his...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197906000-00006

    authors: Stern J,DiGiacinto GV,Housepian EM

    更新日期:1979-06-01 00:00:00

  • Sensory and motor interhemispheric integration after section of different portions of the anterior corpus callosum in nonepileptic patients.

    abstract:OBJECTIVE:We evaluated somatosensory and motor interhemispheric integration in four patients who underwent transection of different portions of the anterior corpus callosum (CC) for removal of an intraventricular cyst. The study goal was to relate their performances to the topographical organization of the CC. METHODS...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000163089.31657.08

    authors: Caillé S,Sauerwein HC,Schiavetto A,Villemure JG,Lassonde M

    更新日期:2005-07-01 00:00:00

  • Cell Therapy for Stroke: A Mechanistic Analysis.

    abstract::Cell therapy has been widely recognized as a promising strategy to enhance recovery in stroke survivors. However, despite an abundance of encouraging preclinical data, successful clinical translation remains elusive. As the field continues to advance, it is important to reexamine prior clinical trials in the context o...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyaa531

    authors: Gu BJ,Kung DK,Chen HI

    更新日期:2020-12-28 00:00:00

  • Neuropsychological functioning and recovery after mild head injury in collegiate athletes.

    abstract:OBJECTIVE:This study prospectively examined neuropsychological functioning in 2300 collegiate football players from 10 National Collegiate Athletic Association Division A universities. The study was designed to determine the presence and duration of neuropsychological symptoms after mild head injury. METHODS:A nonequi...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Macciocchi SN,Barth JT,Alves W,Rimel RW,Jane JA

    更新日期:1996-09-01 00:00:00

  • Continuous assessment of the cerebral vasomotor reactivity in head injury.

    abstract:OBJECTIVE:Cerebrovascular vasomotor reactivity reflects changes in smooth muscle tone in the arterial wall in response to changes in transmural pressure or the concentration of carbon dioxide in blood. We investigated whether slow waves in arterial blood pressure (ABP) and intracranial pressure (ICP) may be used to der...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199707000-00005

    authors: Czosnyka M,Smielewski P,Kirkpatrick P,Laing RJ,Menon D,Pickard JD

    更新日期:1997-07-01 00:00:00

  • Determination of the minimum improvement in pain, disability, and health state associated with cost-effectiveness: introduction of the concept of minimum cost-effective difference.

    abstract:BACKGROUND:Minimum clinical important difference (MCID) has been adopted as the smallest improvement in patient-reported outcome needed to achieve a level of improvement thought to be meaningful to patients. OBJECTIVE:To use a common MCID calculation method with a cost-utility threshold anchor to introduce the concept...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000462079.96571.dc

    authors: Parker SL,McGirt MJ

    更新日期:2015-03-01 00:00:00

  • The Impact of Intracranial Tumor Proximity to White Matter Tracts on Morbidity and Mortality: A Retrospective Diffusion Tensor Imaging Study.

    abstract:Background:Using diffusion tensor imaging (DTI) in neurosurgical planning allows identification of white matter tracts and has been associated with a reduction in postoperative functional deficits. Objective:This study explores the relationship between the lesion-to-tract distance (LTD) and postoperative morbidity and...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyw040

    authors: Meyer EJ,Gaggl W,Gilloon B,Swan B,Greenstein M,Voss J,Hussain N,Holdsworth RL,Nair VA,Meyerand ME,Kuo JS,Baskaya MK,Field AS,Prabhakaran V

    更新日期:2017-02-01 00:00:00

  • A new, more accurate classification of middle cerebral artery aneurysms: computed tomography angiographic study of 1,009 consecutive cases with 1,309 middle cerebral artery aneurysms.

    abstract:BACKGROUND:Classification of middle cerebral artery (MCA) aneurysms is sometimes difficult because the identification of the main MCA bifurcation, the key for accurate classification of MCA aneurysms, is inconsistent and somewhat subjective. OBJECTIVE:To use the meeting point of the M1 and M2 trunks as an objective, g...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000429842.61213.d5

    authors: Elsharkawy A,Lehečka M,Niemelä M,Billon-Grand R,Lehto H,Kivisaari R,Hernesniemi J

    更新日期:2013-07-01 00:00:00

  • Immediate stiffness of the C5-C6 segment after discectomy with the Cloward technique: an in vitro biomechanical study on a human cadaveric model.

    abstract:OBJECTIVE:To determine whether the Cloward technique of cervical discectomy and fusion increases immediate postoperative stiffness of single cervical motion segment after application of interbody dowel bone graft. METHODS:We measured and compared the stiffness of single-motion segments in cadaveric cervical spines bef...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200112000-00019

    authors: Maciejczak A,Ciach M,Radek M Jr,Radek A,Awrejcewicz J

    更新日期:2001-12-01 00:00:00

  • Pediatric cerebellar infarction: case report and review of the literature.

    abstract::Infarction in the vertebrobasilar system is uncommon in children. Cerebellar infarction presenting as a posterior fossa mass lesion is distinctly rare. We recently treated a 13-year-old boy with such a lesion as a complication of basilar artery migraine. A review of the literature on vertebrobasilar infarction in chil...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198205000-00008

    authors: Harbaugh RE,Saunders RL,Reeves AG

    更新日期:1982-05-01 00:00:00

  • Measurement of local directional pressures in the brain with mass.

    abstract::In order to understand the effects and the direction of pressure transmitted from a mass lesion through various brain structures, miniature strain gauges were inserted in different brain locations in eight anesthetized monkeys. Mass lesions were created by inflating a balloon in either of two locations--subcortical in...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199210000-00017

    authors: Kuchiwaki H,Misu N,Takada S,Ishiguri H,Inao S,Sugita K

    更新日期:1992-10-01 00:00:00