Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors.

Abstract:

BACKGROUND:Achieving seizure control in patients with low-grade temporal lobe gliomas or glioneuronal tumors remains highly underappreciated, because seizures are the most frequent presenting symptom and significantly impact patient quality-of-life. OBJECTIVE:To assess how the extent of temporal lobe resection influences seizure outcome. METHODS:We performed a quantitative, comprehensive systematic literature review of seizure control outcomes in 1181 patients with epilepsy across 41 studies after surgical resection of low-grade temporal lobe gliomas and glioneuronal tumors. We measured seizure-freedom rates after subtotal resection vs gross-total lesionectomy alone vs tailored resection, including gross-total lesionectomy with hippocampectomy and/or anterior temporal lobe corticectomy. RESULTS:Included studies were observational case series, and no randomized, controlled trials were identified. Although only 43% of patients were seizure-free after subtotal tumor resection, 79% of individuals were seizure-free after gross-total lesionectomy (OR = 5.00, 95% confidence interval [CI]: 3.33-7.14). Furthermore, tailored resection with hippocampectomy plus corticectomy conferred additional benefit over gross-total lesionectomy alone, with 87% of patients achieving seizure freedom (OR = 1.82, 95% CI: 1.23-2.70). Overall, extended resection with hippocampectomy and/or corticectomy over gross-total lesionectomy alone significantly predicted seizure freedom (OR = 1.18, 95% CI: 1.11-1.26). Age <18 years and mesial temporal location also prognosticated favorable seizure outcome. CONCLUSION:Gross-total lesionectomy of low-grade temporal lobe tumors results in significantly improved seizure control over subtotal resection. Additional tailored resection including the hippocampus and/or adjacent cortex may further improve seizure control, suggesting dual pathology may sometimes allow continued seizures after lesional excision.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Englot DJ,Han SJ,Berger MS,Barbaro NM,Chang EF

doi

10.1227/NEU.0b013e31823c3a30

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

921-8; discussion 928

issue

4

eissn

0148-396X

issn

1524-4040

journal_volume

70

pub_type

杂志文章,评审
  • Interleukin-12-based immunotherapy against rat 9L glioma.

    abstract:OBJECTIVE:Interleukin-12 (IL-12) may be useful for immunotherapy against gliomas because it can reverse the glioma-induced suppression of T-cell proliferation and interferon-gamma production. We postulated that peripheral infusion of IL-12 along with irradiated tumor cells can lead to immunological rejection of 9L glio...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199804000-00097

    authors: Jean WC,Spellman SR,Wallenfriedman MA,Hall WA,Low WC

    更新日期:1998-04-01 00:00:00

  • Severe cervical kyphotic deformities in patients with plexiform neurofibromas: case report.

    abstract::Two patients with cervical plexiform neurofibromas are presented. Each of these patients had severe cervical kyphosis and has undergone anterior decompression, anterior reconstruction, and posterior stabilization. We discuss the surgical management of cervical kyphotic deformities associated with plexiform neurofibrom...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199411000-00025

    authors: Ward BA,Harkey HL,Parent AD,McGuire RA Jr,Kendig RJ

    更新日期:1994-11-01 00:00:00

  • Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature.

    abstract:BACKGROUND:Three-dimensional (3D) printing has revolutionized training, education, and device testing. Understanding the design and physical properties of 3D-printed models is important. OBJECTIVE:To systematically review the design, physical properties, accuracy, and experimental outcomes of 3D-printed vascular model...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyaa134

    authors: Waqas M,Mokin M,Lim J,Vakharia K,Springer ME,Meess KM,Ducharme RW,Ionita CN,Nagesh SVS,Gutierrez LC,Snyder KV,Davies JM,Levy EI,Siddiqui AH

    更新日期:2020-09-15 00:00:00

  • Development of a unique phantom to assess the geometric accuracy of magnetic resonance imaging for stereotactic localization.

    abstract:OBJECTIVE:To test the spatial accuracy of coordinates generated from magnetic resonance imaging (MRI) scans, using the Brown-Roberts-Wells head frame and localizer system (Radionics, Inc., Burlington, MA). METHODS:An anthropomorphic head phantom, consisting of a two-dimensional lattice of acrylic spheres (4-mm diamete...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199912000-00030

    authors: Orth RC,Sinha P,Madsen EL,Frank G,Korosec FR,Mackie TR,Mehta MP

    更新日期:1999-12-01 00:00:00

  • Air embolism during trans-sphenoidal pituitary operations.

    abstract::Doppler ultrasonic cardiac monitoring of patients undergoing trans-sphenoidal pituitary operations in the semisitting position has revealed the occurrence of venous air embolism in 3 of 31 consecutive cases. One such case is presented. Air may be drawn into the venous system whenever a gradient exists between the site...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197801000-00008

    authors: Newfield P,Albin MS,Chestnut JS,Maroon J

    更新日期:1978-01-01 00:00:00

  • A novel murine elastase saccular aneurysm model for studying bone marrow progenitor-derived cell-mediated processes in aneurysm formation.

    abstract:BACKGROUND:Although there are several large-species animal models for saccular aneurysms, there is a need for a simple, reproducible saccular aneurysm model in mice. OBJECTIVE:To develop a murine saccular aneurysm model, which replicates key characteristics that occur in the formation of human cerebral aneurysms. MET...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000365616.46414.2B

    authors: Hoh BL,Velat GJ,Wilmer EN,Hosaka K,Fisher RC,Scott EW

    更新日期:2010-03-01 00:00:00

  • Treatment of extracranial and intracranial aneurysms and arteriovenous fistulae using stent grafts.

    abstract:OBJECTIVE:Treatment of 11 patients with aneurysms or arteriovenous fistulae of the craniocervical arteries with stent grafts. METHODS:Peripheral stent grafts were deployed in two extracranial internal carotid arteries. Coronary stent grafts were used to treat two giant aneurysms, five direct carotid-cavernous fistulae...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000134455.02947.1f

    authors: Felber S,Henkes H,Weber W,Miloslavski E,Brew S,Kühne D

    更新日期:2004-09-01 00:00:00

  • Anatomic dissection and classic three-dimensional documentation: a unit of education for neurosurgical anatomy revisited.

    abstract:OBJECTIVE AND IMPORTANCE:Despite development of computer-assisted neurosurgical navigation, learning by dissecting anatomic specimens is still important. CLINICAL PRESENTATION:We describe the processes from preparation of specimens for cranial dissection to documentation of three-dimensional (3-D) stereoscopic picture...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000210247.37628.43

    authors: Shimizu S,Tanaka R,Rhoton AL Jr,Fukushima Y,Osawa S,Kawashima M,Oka H,Fujii K

    更新日期:2006-05-01 00:00:00

  • Should Levetiracetam or Phenytoin Be Used for Posttraumatic Seizure Prophylaxis? A Systematic Review of the Literature and Meta-analysis.

    abstract:BACKGROUND:Posttraumatic seizure (PTS) is a significant complication of traumatic brain injury (TBI). OBJECTIVE:To perform a systematic review and meta-analysis to compare levetiracetam with phenytoin for seizure prophylaxis in patients diagnosed with severe TBI. METHODS:An inclusive search of several electronic data...

    journal_title:Neurosurgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1227/NEU.0000000000001445

    authors: Khan NR,VanLandingham MA,Fierst TM,Hymel C,Hoes K,Evans LT,Mayer R,Barker F,Klimo P Jr

    更新日期:2016-12-01 00:00:00

  • Spontaneous resolution of chronic epidural hematomas: report of three cases.

    abstract::We report three cases of the spontaneous resolution of a traumatic chronic epidural hematoma. The patients were young adults with only mild headache after trauma. All patients were treated conservatively because of the very mild symptoms and the time lapse of 1 to 2 weeks between trauma and our unexpected detection of...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198407000-00018

    authors: Tochio H,Waga S,Tashiro H,Takeuchi T,Miyazaki M

    更新日期:1984-07-01 00:00:00

  • Venous thromboembolism in neurosurgery and neurology patients: a review.

    abstract::Thromboembolism is a common problem in neurosurgery and neurology patients. Within this diverse population are subpopulations of patients with varying degrees of thromboembolic risk: low, moderate, and high. Patients at substantial risk for deep vein thrombosis and pulmonary embolism include those with spinal cord inj...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/00006123-199402000-00012

    authors: Hamilton MG,Hull RD,Pineo GF

    更新日期:1994-02-01 00:00:00

  • Nonvestibular schwannomas of the brain: a 7-year experience.

    abstract:OBJECTIVE:Nonvestibular schwannomas are uncommon tumors of the brain. Trigeminal nerve schwannomas are the most common of this group, followed by glossopharyngeal, vagal, facial, accessory, hypoglossal, oculomotor, trochlear, and abducens nerve schwannomas, in descending order of frequency. We present a series of nonve...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200203000-00002

    authors: Sarma S,Sekhar LN,Schessel DA

    更新日期:2002-03-01 00:00:00

  • Anterior cervical discectomy and corpectomy.

    abstract:OBJECTIVE:The objective of this review article is to describe the authors' operative technique for performing anterior cervical corpectomy and fusion. METHODS:The authors reviewed their operative technique and experience to clearly detail the general methods utilized to safely and effectively perform anterior cervical...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/01.NEU.0000205285.20336.C2

    authors: Perez-Cruet MJ,Samartzis D,Fessler RG

    更新日期:2006-04-01 00:00:00

  • Civilian craniocerebral gunshot wounds.

    abstract::Experience with 120 patients who incurred a gunshot wound to the head with dural penetration is presented. All of the patients were managed by a standard resuscitation protocol and assigned a clinical grade based on their level of consciousness both at the time of presentation and at 2 to 4 months after injury. Fifty ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199107000-00011

    authors: Benzel EC,Day WT,Kesterson L,Willis BK,Kessler CW,Modling D,Hadden TA

    更新日期:1991-07-01 00:00:00

  • Clinical utility of allogeneic skull discs in human craniotomy.

    abstract::One hundred fifteen burr hole defects were filled with sterilized human cadaver skull in 45 patients ranging in age between 10 and 88 years. One to 6 allogeneic skull discs per patient were placed in all areas of the calvaria. The length of postoperative observation ranges between 6 months and 5 years. No instances of...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198402000-00011

    authors: Prolo DJ,Gutierrez RV,DeVine JS,Oklund SA

    更新日期:1984-02-01 00:00:00

  • Three-dimensional computed tomographic reformation of the spine, skull, and brain from axial images.

    abstract::Three-dimensional (3D) images were reconstructed from axial computed tomographic scans using the new 3D83 (General Electric Co.) software. Images were reformatted as a movie in multiple frames, each consisting of a discrete 3D scene, and were rotated 360 degrees in 3D space. Improvement in shading and surface algorith...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198601000-00009

    authors: Virapongse C,Shapiro M,Gmitro A,Sarwar M

    更新日期:1986-01-01 00:00:00

  • Symptomatic Adjacent Level Disease Requiring Surgery: Analysis of 10-Year Results From a Prospective, Randomized, Clinical Trial Comparing Cervical Disc Arthroplasty to Anterior Cervical Fusion.

    abstract:BACKGROUND:Ten-year follow-up data from the US Food and Drug Administration investigational device exemption trial comparing BRYAN® Cervical Disc (Medtronic, Dublin, Ireland) arthroplasty to anterior cervical discectomy and fusion (ACDF) demonstrated that disc arthroplasty maintained range of motion and improvements in...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/neuros/nyy118

    authors: Ghobrial GM,Lavelle WF,Florman JE,Riew KD,Levi AD

    更新日期:2019-02-01 00:00:00

  • Clinical problem-solving: brachial plexus closed injury and reconstruction.

    abstract:OBJECTIVE:Current management of severe brachial plexus injury has undergone recent modifications, and surgical options have expanded. METHODS:The case of a man with a severe closed brachial plexus injury resulting from a motorcycle accident is presented. The patient is found to have upper root avulsions that deprive h...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000333305.57060.00

    authors: Ranalli NJ,Kline DG,McGarvey ML,Boulis NM,Zager EL

    更新日期:2008-06-01 00:00:00

  • Primary pituitary carcinoma: a clinical pathological study.

    abstract::A 60-year-old woman presented with a history of headache and rapidly progressive complete bilateral ophthalmoplegia. Her endocrine function was normal. Radiographic studies revealed signs of diffuse destruction of the sella turcica by a tumor without suprasellar extension. Biopsies of the lesion within the sphenoid si...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Nudleman KL,Choi B,Kusske JA

    更新日期:1985-01-01 00:00:00

  • Posterior interhemispheric approach: surgical technique, application to vascular lesions, and benefits of gravity retraction.

    abstract:OBJECTIVE:To review an experience with the posterior interhemispheric approach applied to vascular lesions in the posterior midline, to examine the effects of patient position and gravity retraction of the occipital lobe, and to identify circumstances requiring increased exposure by sectioning the falx and tentorium. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000219880.66309.85

    authors: Chi JH,Lawton MT

    更新日期:2006-07-01 00:00:00

  • Surgical Decision Making From Image-Based Biophysical Modeling of Glioblastoma: Not Ready for Primetime.

    abstract:BACKGROUND:Biophysical modeling of glioma is gaining more interest for clinical practice. The most popular model describes aggressivity of tumor cells by two parameters: net proliferation rate (ρ) and propensity to migrate (D). The ratio ρ/D, which can be estimated from a single preoperative magnetic resonance imaging ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyw186

    authors: Amelot A,Deroulers C,Badoual M,Polivka M,Adle-Biassette H,Houdart E,Carpentier AF,Froelich S,Mandonnet E

    更新日期:2017-05-01 00:00:00

  • Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review.

    abstract:BACKGROUND:Primary leptomeningeal gliomatosis (PLG) is a poorly recognized tumor of the central nervous system. OBJECTIVE:To describe the histopathological, immunohistochemical, and molecular features of PLG. METHODS:Results of our multicentric retrospective study of 6 PLG cases (3 pediatric and 3 adult) were compare...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.1227/NEU.0000000000001028

    authors: Tauziede-Espariat A,Maues de Paula A,Pages M,Laquerriere A,Caietta E,Delpont B,Viennet G,Medeiros de Bustos E,Moulin T,Barnerias C,Vauleon E,Grill J,Chiforeanu D,Vasiljevic A,Varlet P

    更新日期:2016-03-01 00:00:00

  • Deep Brain Stimulation for Parkinson Disease Does not Worsen or Improve Postural Instability: A Prospective Cohort Trial.

    abstract:BACKGROUND:Falls and postural instability (PI) are major sources of morbidity in Parkinson disease (PD). Deep brain stimulation (DBS) is a major therapy for PD. The effects of DBS on PI and falls remain controversial. OBJECTIVE:To study if DBS worsens PI, validated measures of PI (Timed Up and Go, Berg Balance Scale, ...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1093/neuros/nyx602

    authors: Brandmeir NJ,Brandmeir CL,Carr D,Kuzma K,McInerney J

    更新日期:2018-12-01 00:00:00

  • Surgical Decompression of High-Grade Spinal Cord Compression from Hormone Refractory Metastatic Prostate Cancer.

    abstract:BACKGROUND:Spine and nonspine skeletal metastases occur in more than 80% of patients with prostate cancer. OBJECTIVE:To examine the characteristics of the patient population undergoing surgery for the treatment of prostate cancer metastatic to the spine. METHODS:A retrospective chart review was performed on all patie...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyx292

    authors: Chohan MO,Kahn S,Cederquist G,Reiner AS,Schwab J,Laufer I,Bilsky M

    更新日期:2018-05-01 00:00:00

  • Clinical evaluation of a depth electroencephalography electrode.

    abstract::Stereo depth electroencephalography (EEG) is of proven benefit in lateralizing and localizing seizure origin in select cases of epilepsy. There are potential hazards and technical considerations inherent with depth EEG, however, that have limited the general applicability of this technique. A new depth EEG electrode w...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198305000-00015

    authors: Maxwell RE,Gates JR,Fiol ME,Johnson MJ,Yap JC,Leppik IE,Gumnit RJ

    更新日期:1983-05-01 00:00:00

  • Injuries involving the transverse atlantal ligament: classification and treatment guidelines based upon experience with 39 injuries.

    abstract::Comprehensive anatomic and clinical analyses of 39 patients with injuries involving the transverse atlantal ligament or its osseous insertions were performed to assess the morphology of the injured ligaments and the patients' capacity to heal. Injuries of the upper cervical spine were screened with plain radiographs, ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199601000-00012

    authors: Dickman CA,Greene KA,Sonntag VK

    更新日期:1996-01-01 00:00:00

  • Cranial surgery in ancient Peru.

    abstract::Trephination is the oldest known surgical technique. Peru has been recognized as a major source of ancient trephined skulls, many of which date back 2300 years. This presentation reviews from a neurosurgical perspective many of the archaeological studies performed on these skulls. Comparative osteology has shown that ...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1227/00006123-198810000-00001

    authors: Rifkinson-Mann S

    更新日期:1988-10-01 00:00:00

  • cerebellar oligodendroglioma in a child.

    abstract::Oligodendrogliomas occur primarily in the cerebral hemispheres of adults. A rare case of an oligodendroglioma in the cerebellum of a child is presented. The tendency for oligodendroglioma to metastasize through the cerebrospinal fluid (CSF) is reviewed and emphasized. A recommendation for CSF cytology and possible spi...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198005000-00010

    authors: Holladay FP,Fruin AH

    更新日期:1980-05-01 00:00:00

  • Brain vascularization by transplanted omentum: a possible treatment of cerebral ischemia.

    abstract::The authors report their experience with experimental brain vascularization with the use of transplanted omentum majus. The possibility of treating cerebral ischemia with this method is discussed. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197711000-00006

    authors: Yonekawa Y,Yaşargil MG

    更新日期:1977-11-01 00:00:00

  • A new ventriculoperitoneal shunt with a telemetric intracranial pressure sensor: clinical experience in 94 patients with hydrocephalus.

    abstract:OBJECTIVE:We have developed a telemetric intracranial pressure sensor (OSAKA telesensor; Nagano Keiki Seisakusyo Co. Ltd., Tokyo, Japan) and investigated the clinical usefulness of new ventriculoperitoneal shunting with an OSAKA telesensor, an on-off valve, and a programmable valve. METHODS:The OSAKA telesensor was ap...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199705000-00009

    authors: Miyake H,Ohta T,Kajimoto Y,Matsukawa M

    更新日期:1997-05-01 00:00:00